Patents by Inventor Hao Hong

Hao Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12012335
    Abstract: 3D bundle-shaped multi-walled carbon nanotubes and preparation method, includes the following steps: uniformly mixing bi-component alloy catalyst and transition metal in an inert gas environment in order to obtain a three-component nano-intermetallic alloy catalyst; disposing the intermetallic catalyst on the substrate; allowing hydrogen to flow through the substrate, and heating the substrate to a first temperature, and using the hydrogen to undergo a reduction of the intermetallic catalyst at the first temperature; applying a protective gas and a carbon source gas, heating the substrate to a second temperature, undergoing a reaction at the second temperature to generate the 3D bundle-shaped multi-walled carbon nanotubes, and collecting the 3D bundle-shaped multi-walled carbon nanotubes after annealing; wherein the second temperature is greater than or equal to the first temperature; a working electrode includes conductive drain material, a conductive bonding gent and a plurality of 3D bundle-shaped multi-wa
    Type: Grant
    Filed: October 18, 2021
    Date of Patent: June 18, 2024
    Assignee: KUN SHAN UNIVERSITY
    Inventors: Hao-Lin Hsu, Jean-Hong Chen
  • Publication number: 20240191008
    Abstract: Provided is an amination method for a polystyrene-type resin, and a method for immobilizing an enzyme using an aminated polystyrene-type resin. The amination method includes: in a solvent, a catalyst is used to catalyze a polystyrene-type resin and an enamine salt to perform a Friedel-Crafts alkylation reaction, to obtain an aminated polystyrene-type resin, herein the catalyst is a Lewis acid catalyst. By means of the Friedel-Crafts alkylation reaction, the enamine salt is grafted onto the polystyrene-type resin, and the polystyrene-type resin is aminated. The conditions of the Friedel-Crafts alkylation reaction are easy to control, the post-treatment process is simple, and it is only necessary to remove the catalyst and the unreacted enamine salt by washing. Therefore, the above amination method in the present application has few steps and is simple and easy to implement. Meanwhile, the amination method further avoids the use of a noble metal catalyst, thereby reducing production cost.
    Type: Application
    Filed: May 10, 2021
    Publication date: June 13, 2024
    Inventors: Hao HONG, Yi XIAO, Na ZHANG, Han LIN, Long PAN, Williams VYASA, Liteng MA, Yuxia CUI, Yanyan GAO
  • Patent number: 12009949
    Abstract: A signal receiver includes a first transistor, a second transistor, a load circuit, an amplifying circuit and a load circuit. The first transistor has a first end receiving a power voltage, and a control end receive a first input signal. The second transistor has a first end receiving the power voltage, and a control end receiving a second input signal, wherein the first input signal and the second input signal are differential signals and transit between a first voltage and a reference ground voltage, the first voltage is larger than the power voltage. The load circuit is coupled to the first transistor and the second transistor. The amplifying circuit generates an output signal according a first signal on the second end of the first transistor and a second signal on the second end of the second transistor.
    Type: Grant
    Filed: October 14, 2021
    Date of Patent: June 11, 2024
    Assignee: Novatek Microelectronics Corp.
    Inventors: Hao-Che Hsu, Chin-Tung Chan, Ying-Cheng Lin, Ren-Hong Luo
  • Patent number: 12005142
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one liposome and a therapeutic agent for treating depression or anxiety, with a therapeutic agent to lipid ratio equal to or higher than about 0.15. The pharmaceutical composition improves the pharmacokinetic profile and sustains the release of the therapeutic agent. Also provided is the method for treating depression or anxiety using the pharmaceutical composition disclosed herein.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: June 11, 2024
    Inventors: Keelung Hong, Yi-Yu Lin, Hao-Wen Kao
  • Publication number: 20240182942
    Abstract: The preparation method for a polypeptide includes the steps of constructing an engineering strain for fusion-expressing a polypeptide gene with a Sumo tag, and inducing the engineering strain for the soluble expression of a polypeptide, obtaining a crude protein containing a polypeptide precursor from the engineering strain by purification, cleaving the crude protein containing the polypeptide precursor by a Ulp1 protease to remove the Sumo tag, and purifying a cleavage product of the Ulp1 protease by a method of acetonitrile combined with heating precipitation or a method of precipitation with hexafluoro isopropanol to obtain the polypeptide.
    Type: Application
    Filed: May 31, 2021
    Publication date: June 6, 2024
    Applicant: ASYMCHEM LABORATORIES (TIANJIN) CO., LTD.
    Inventors: Hao HONG, Gage JAMES, Yi XIAO, Na ZHANG, Xuecheng JIAO, Junqi ZHAO, Lei WANG, Xiangyu MENG, Mujiao ZHANG
  • Publication number: 20240184578
    Abstract: Methods and embodiments of a high-performance parallel multi-literal matching algorithm called NeoHarry. A chunk of data comprising a character string comprising n bytes is sampled for a byte stream, and data in the sampled chunk are pre-shifted to create shifted copies of data at multiple sampled locations. A mask table is generated having column vectors containing match indicia identifying potential character matches. A look up of the mask table at multiple sampled locations using the pre-shifted data is performed for a target literal character pattern. The mask table lookup results are combined to generate match candidates and exact match verification is performed to identify any generated match candidates that match the target literal character pattern. NeoHarry uses a column-vector-based shift-or model and implements a cross-domain shift algorithm under which character patterns spanning two domains are identified.
    Type: Application
    Filed: February 13, 2024
    Publication date: June 6, 2024
    Inventors: Hao CHANG, Geoffrey LANGDALE, Xiang WANG, Yang HONG, Wenjun ZHU, Kun QIU, Xusheng LU
  • Publication number: 20240182884
    Abstract: The application provides an enzyme immobilization carrier and a preparation method thereof, an immobilized enzyme and a preparation method thereof. The above enzyme immobilization carrier is obtained by an amino modification or a cyanuric chloride modification of super-crosslinked polyvinyl alcohol. The use of the enzyme immobilization carrier provided by the application may effectively improve the stability and reusability of the immobilized enzyme. Moreover, due to the use of the form of enzyme covalent linkage, compared with an embedding method, the preparation method is no need for chemical reagent immersion and the like, it is beneficial to maintain the own activity of the enzyme, and promote the immobilized enzyme to have the better activity while the stability and reusability are kept.
    Type: Application
    Filed: April 12, 2021
    Publication date: June 6, 2024
    Inventors: Hao HONG, Yi XIAO, Na ZHANG, Han LIN, Pong PAN, Williams VYASA, Liteng MA, Yuxia CUI, Yanyan GAO
  • Patent number: 11993552
    Abstract: The present disclosure discloses a method and a device for continuously synthesizing cyclopropane compounds. The method includes the following steps: continuously performing a synthetic reaction of a diazomethane precursor in a first reactor, the reaction product of the first reactor flowing into a separator for stratification, the organic phase obtained by stratification overflowing into a second reactor, continuously consuming the diazomethane precursor in a second reactor to prepare diazomethane and performing an electron-rich monoolefin cyclopropanation reaction in situ so as to obtain the cyclopropane compound.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: May 28, 2024
    Assignee: ASYMCHEM LABORATORIES (TIANJIN) CO., LTD.
    Inventors: Hao Hong, Jiangping Lu, Xichun Feng, Xingfang Sun, Feng Zhang
  • Patent number: 11994011
    Abstract: The present invention discloses a permanent packer and an extended gas lift method using the permanent packer, the method comprising: S1. imbedding the extended gas lift embedded pipe when setting the permanent packer, wherein the extended gas lift embedded pipe has an upper end being closed and a lower end being open, is provided therein with a one-way valve through which the fluid can pass from top to bottom; S2. lowering a breaking device from the production casing when in the extended gas lift, to break the upper end of the extended gas lift embedded pipe such that the upper and lower ends of the extended gas lift embedded pipe are communicated; and S3. injecting gas into the production casing, lifting the accumulated liquid in the bottom hole to the ground surface, to complete the extended gas lift.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: May 28, 2024
    Assignees: PetroChina Company Limited, Sichuan Shengnuo Oil. and Gas Engineering Technology Service Co. Ltd
    Inventors: Weilin Wang, Huiyun Ma, Changqing Ye, Hao Tan, Hanbing Tang, Daogang Cai, Xueqiang Wang, Yukui Hong, Fengjing Sun, Wei Zhou, Ting Zhang, Zonghao Dong, Yan Huang, Yun Miao
  • Publication number: 20240162308
    Abstract: The present disclosure provides a semiconductor structure with having a source/drain feature with a central cavity, and a source/drain contact feature formed in central cavity of the source/drain region, wherein the source/drain contact feature is nearly wrapped around by the source/drain region. The source/drain contact feature may extend to a lower most of a plurality semiconductor layers.
    Type: Application
    Filed: February 9, 2023
    Publication date: May 16, 2024
    Inventors: Pin Chun SHEN, Che Chia CHANG, Li-Ying WU, Jen-Hsiang LU, Wen-Chiang HONG, Chun-Wing YEUNG, Ta-Chun LIN, Chun-Sheng LIANG, Shih-Hsun CHANG, Chih-Hao CHANG, Yi-Hsien CHEN
  • Publication number: 20240162310
    Abstract: Semiconductor structures and methods for manufacturing the same are provided. The semiconductor structure includes a gate structure formed over a substrate, and a first source/drain (S/D) structure formed adjacent to the gate structure. The semiconductor structure includes a first contact structure formed over a first side of the first S/D structure, and a portion of the first contact structure is lower than a top surface of the first S/D structure. The semiconductor structure includes a second contact structure formed over a second side of the first S/D structure, and the second contact structure is in direct contact with the first contact structure.
    Type: Application
    Filed: March 8, 2023
    Publication date: May 16, 2024
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Ta-Chun LIN, Wen-Chiang HONG, Chih-Hao CHANG
  • Publication number: 20240152864
    Abstract: An inventory planning system and an inventory planning method for short expiration goods are provided. The inventory planning system includes: a demand forecast model configured to provide a future sales prediction of the at least one short expiration goods according to an expiration period information, a promotion information and a historical sales information of at least one short expiration goods; a promotion forecast model configured to provide a future promotions sales of the at least one short expiration goods according to the expiration period information, the promotion information and the historical sales information of the at least one short expiration goods; and an inventory planning model configured to provide a purchase quantity recommendation of the at least one short expiration goods according to a current stock, the future sales prediction and the future promotions sales of the at least one short expiration goods.
    Type: Application
    Filed: December 16, 2022
    Publication date: May 9, 2024
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Sian-Hong HUANG, Hao-Chun CHUANG
  • Publication number: 20240135976
    Abstract: A memory includes a memory array and a single-ended sense amplifier circuit. The memory array includes wordlines, bitlines, and memory cells. The bitlines include a first bitline, routed on a first metal layer but not a second metal layer, and a second bitline, routed on the first metal layer and the second metal layer. Each of the memory cells is coupled to one of the wordlines. The memory cells include a first group of memory cells, coupled to the first bitline, and a second group of memory cells, coupled to the second bitline, where the first group of memory cells and the second group of memory cells are located at a same column. The single-ended sense amplifier circuit performs a read operation upon a target memory cell through single-ended sensing when a selected wordline is enabled.
    Type: Application
    Filed: September 20, 2023
    Publication date: April 25, 2024
    Applicant: MEDIATEK INC.
    Inventor: Chi-Hao Hong
  • Publication number: 20240124853
    Abstract: Provided are transaminase mutants and uses thereof. The transaminase mutant is obtained by one or more amino acid mutations occurring in SEQ ID NO: 2 or is a mutant with a conserved amino acid mutation obtained by taking the sequence SEQ ID NO: 1 of a wild-type CvTA transaminase as a reference. Compared with wild-type transaminases, the catalytic activity of the mutant is improved to different degrees, so that the production efficiency of chiral amine compound synthesis may be improved.
    Type: Application
    Filed: July 6, 2021
    Publication date: April 18, 2024
    Inventors: Hao Hong, Gage James, Yi Xiao, Na Zhang, Xuecheng Jiao, Yulei Ma, Huiyan Mou, Zujian Wang, Kaihua Sun, Xiang Li, Tong Zhao, Shan Cao
  • Patent number: 11961884
    Abstract: The present disclosure describes a semiconductor device with a fill structure. The semiconductor structure includes first and second fin structures on a substrate, an isolation region on the substrate and between the first and second fin structures, a first gate structure disposed on the first fin structure and the isolation region, a second gate structure disposed on the second fin structure and the isolation region, and the fill structure on the isolation region and between the first and second gate structures. The fill structure includes a dielectric structure between the first and second gate structures and an air gap enclosed by the dielectric structure. The air gap is below top surfaces of the first and second fin structures.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 16, 2024
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Hsiu-Yung Lin, Yen Chuang, Min-Hao Hong
  • Publication number: 20240115972
    Abstract: Provided are a continuous post-treatment method and device for a penem compound. The method includes the following steps: S1, performing continuous extraction on a reaction crude product of a penem compound, to obtain an extraction heavy phase and an extraction light phase; S2, performing continuous solid-liquid separation on the extraction heavy phase, to obtain a liquid phase separation product; S3, performing continuous pH adjustment on the liquid phase separation product until a pH value thereof is 6.1-6.3, to obtain pH-adjusted solution; and S4, performing continuous crystallization treatment on the pH-adjusted solution by a first crystallization solvent, to obtain a penem compound product. The use of the method for the post-treatment of the reaction crude product of the penem compound has the advantages of high treatment speed and high efficiency, and stable material properties and a low deterioration rate during the treatment, and has better control over the yield and purity of a target product.
    Type: Application
    Filed: October 15, 2019
    Publication date: April 11, 2024
    Inventors: Hao HONG, Liang HONG, Jian TAO, Jinhai GUO, Xian CHENG, Yan ZHANG
  • Publication number: 20240120337
    Abstract: A semiconductor device structure includes a first dielectric wall, a plurality of first semiconductor layers vertically stacked and extending outwardly from a first side of the first dielectric wall, each first semiconductor layer has a first width, a plurality of second semiconductor layers vertically stacked and extending outwardly from a second side of the first dielectric wall, each second semiconductor layer has a second width, a plurality of third semiconductor layers disposed adjacent the second side of the first dielectric wall, each third semiconductor layer has a third width greater than the second width, a first gate electrode layer surrounding at least three surfaces of each of the first semiconductor layers, the first gate electrode layer having a first conductivity type, and a second gate electrode layer surrounding at least three surfaces of each of the second semiconductor layers, the second gate electrode layer having a second conductivity type opposite the first conductivity type.
    Type: Application
    Filed: January 15, 2023
    Publication date: April 11, 2024
    Inventors: Ta-Chun LIN, Chih-Hung HSIEH, Chun-Sheng LIANG, Wen-Chiang HONG, Chun-Wing YEUNG, Kuo-Hua PAN, Chih-Hao CHANG, Jhon Jhy LIAW
  • Publication number: 20240117395
    Abstract: Provided is a method for synthesizing a chiral amine compound. A transaminase is used to transaminate a ketone substrate under the action of an amino donor, to obtain the chiral amine compound; and the conserved amino acid sequence region of the transaminase at least includes a region 1 (MAGLWCVN) and a region 2 (YNTFFKT). With the transaminase with the specific conserved amino acid sequence region to synthesize a large sterically hindered chiral amine, the enzyme catalytic reaction volume is small, the synthesizing route is short, the product yield is high, a high-cost noble metal is not required for catalysis under the synthesizing conditions, three wastes are reduced, and the production cost is saved.
    Type: Application
    Filed: July 6, 2021
    Publication date: April 11, 2024
    Inventors: Hao Hong, Gage James, Yi Xiao, Na Zhang, Xuecheng Jiao, Yulei Ma, Huiyan Mou, Zujian Wang, Kaihua Sun, Ru Jia, Fang Liu, Wenjing Liu
  • Patent number: 11952575
    Abstract: A transaminase mutant and use hereof, the amino acid sequence of the transaminase mutant is an amino acid sequence in which the amino acid sequence as represented by SEQ ID NO: 1 is mutated, the mutated amino acid position being one or more selected from among F89, K193, P243, V234, I262, Q280, V379, R416, A417 and C418. The enzymatic activity and/or stability of the transaminase mutant is improved.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: April 9, 2024
    Assignee: ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD
    Inventors: Hao Hong, Gage James, Jiangping Lu, Xingfu Xu, Wenyan Yu, Xin Huang, Yulei Ma, Yibing Cheng
  • Patent number: 11944636
    Abstract: This invention discloses a medicinal composition includes a non-coding RNA molecule and an antibody targeting a tumor antigen for preventing and/or treating cancer. This invention uses the synergistic combination of a non-coding RNA molecule or its functional variant or homologue, and an antibody targeting a tumor antigen to prevent and/or treat cancer, thereby providing a novel and effective method in preventing and/or treating various cancers.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: April 2, 2024
    Assignee: Macau University of Science and Technology
    Inventors: Zhi-Hong Jiang, Lee-Fong Yau, Tian-Tian Tong, Hao Huang, Kua Hu, Elaine Lai-Han Leung