Patents by Inventor Hao Yan

Hao Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMAGING SYSTEM, IMAGING METHOD AND RADIOTHERAPY SYSTEM
    Publication number: 20220087632
    Abstract: Embodiments of the present disclosure provide an imaging system, an imaging method, and a radiotherapy system. The imaging system is used for imaging a patient, including: a X-ray tube and a flat-panel detector, the X-ray tube is arranged opposite to the flat-panel detector, the X-ray tube emits X-rays, the flat-panel detector detects the X-rays to generate image data, and a geometric center of the flat-panel detector has an offset relative to an orthographic projection of a focal of the X-ray tube on the flat-panel detector. In the embodiments of the present disclosure, an imaging accuracy obtained based on the image data is better, and an effect of image guidance in tumor treatment is improved.
    Type: Application
    Filed: September 23, 2021
    Publication date: March 24, 2022
    Inventors: Hao YAN, Jinsheng LI, Fangzheng CHEN, Daliang LI
  • RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES
    Publication number: 20220056450
    Abstract: Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory).
    Type: Application
    Filed: November 5, 2021
    Publication date: February 24, 2022
    Inventors: Hao YAN, Yung CHANG, Xiaowei LIU, Fei ZHANG, Xiaodong QI
  • RNA nanostructures and methods of making and using RNA nanostructures
    Patent number: 11254941
    Abstract: Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory).
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: February 22, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Hao Yan, Yung Chang, Xiaowei Liu, Fei Zhang, Xiaodong Qi
  • RNA-nanostructured double robots and methods of use thereof
    Patent number: 11242533
    Abstract: Described herein are immuno-stimulatory RNA nanostructures (which comprises a single-stranded RNA (ssRNA) molecule, wherein the ssRNA molecule forms at least one paranemic cohesion crossover), as well as compositions and methods of use thereof.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: February 8, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Yung Chang, Hao Yan, Xiaodong Qi, Fei Zhang
  • Target tracking and irradiation method and device using radiotherapy apparatus and radiotherapy apparatus
    Patent number: 11241589
    Abstract: A method for tracking and irradiating a target using a radiotherapy apparatus, a device and a radiotherapy apparatus are provided. The radiotherapy apparatus includes a first ray source, a second ray source, and at least one detector. The method includes: moving the first ray source to a first location to emit a ray beam; receiving the ray beam emitted from the first ray source at the first location and generating first image data of a target according to the received ray beam, by the detector; and adjusting the second ray source according to the first image data to make the second ray source move to the first location and an emitted ray beam pass through the target, wherein a time taken for the second ray source to move to the first location is a positive integer multiple of a preset respiratory period of a patient.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: February 8, 2022
    Assignee: OUR NEW MEDICAL TECHNOLOGIES
    Inventors: Jiuliang Li, Hao Yan, Jinsheng Li
  • METHOD, APPARATUS AND SYSTEM FOR DIAGNOSING STATUS OF RADIOTHERAPY EQUIPMENT AND STORAGE MEDIUM
    Publication number: 20220037006
    Abstract: A method for diagnosing status of radiotherapy equipment includes: acquiring real-time detection data in an operating process of radiotherapy equipment; and processing the real-time detection data by using a status diagnosis model, and generating and outputting real-time status diagnosis data, wherein the real-time status diagnosis data includes at least one of real-time fault diagnosis data and real-time aging diagnosis data.
    Type: Application
    Filed: September 14, 2018
    Publication date: February 3, 2022
    Inventors: Peng ZAN, Hao YAN
  • METHOD AND APPARATUS FOR PERFORMING IMAGE GUIDANCE, MEDICAL EQUIPMENT, AND COMPUTER-READABLE STORAGE MEDIUM
    Publication number: 20220020164
    Abstract: Provided is a method for performing image guidance, including: acquiring a 3D magnetic resonance (MR) image of a target individual, wherein at least one region range of an object of interest is marked in the 3D MR image; acquiring a reference 3D image of the target individual, wherein the reference 3D image is a 3D-reconstructed computed tomography (CT) image; performing a 3D-3D registration on the 3D MR image and the reference 3D image, so as to mark each region range of the object of interest in the reference 3D image; and performing image guidance on the basis that the reference 3D image is adopted to characterize an initial position state.
    Type: Application
    Filed: October 30, 2018
    Publication date: January 20, 2022
    Inventors: Zhongya WANG, Daliang LI, Hao YAN, Jiuliang LI
  • Method and apparatus of correcting collimator of radiotherapy equipment
    Patent number: 11227700
    Abstract: Embodiments of the present disclosure provide a method and an apparatus of correcting a collimator, which may correct a position of a collimator of a gamma knife apparatus. The method includes: separately obtaining a projection image of rays sequentially passing through collimation holes and an isocenter plane in the collimator in cases where the collimator moves to M positions; determining a target position with a highest degree of alignment of the collimator from the M positions according to obtained projection images of rays; recording position parameters corresponding to the target position, so as to control the collimator to move to the target position in a case where the a gamma knife apparatus is used for treatment.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: January 18, 2022
    Inventors: Jiuliang Li, Hao Yan, Jinsheng Li, Tianchang Gou, Chun Luo
  • Method for designing an impeller with a small hub-tip ratio and a rim-driven pump obtained by the method
    Patent number: 11215189
    Abstract: A method for designing an impeller with a small hub-tip ratio includes the following steps: S1: obtaining an outer diameter D of the impeller with the small hub-tip ratio; S2: determining the number of blades and an airfoil of the blade of the impeller with the small hub-tip ratio; S3: obtaining a blade solidity sy at a rim of the impeller with the small hub-tip ratio and a blade solidity sg at a hub of the impeller with the small hub-tip ratio; S4: dividing the blades of the impeller with the small hub-tip ratio into m cylindrical sections in an equidistant manner, marking the cylindrical sections as 1-1, 2-2, . . . , m-m in sequence from the hub to the rim, and obtaining an airfoil setting angle ?L of each of the cylindrical sections; and S5: performing a correction on the value of the airfoil setting angle ?L in S4.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: January 4, 2022
    Assignee: HEFEI UNIVERSITY OF TECHNOLOGY
    Inventors: Hao Yan, Qiang Li, Xiaozhen Su, Yu Zhang, Liang Chen, Liping Chai, Haixia Shi
  • METHOD OF FABRICATING DISPLAY PANEL, DISPLAY PANEL, AND DISPLAY APPARATUS
    Publication number: 20210408455
    Abstract: A method of fabricating a display panel is provided. The method includes providing a substrate including a plurality of light emitting elements; forming a first protective layer on a side of the substrate; treating the first protective layer to obtain a first adhesive portion, a second adhesive portion, and a third adhesive portion, the third adhesive portion having an adhesive strength smaller than an adhesive strength of the first adhesive portion, and smaller than an adhesive strength of the second adhesive portion; and removing the third adhesive portion from the substrate to form a bendable portion of the substrate. The bendable portion of the substrate spaces apart a first portion of the substrate from a second portion of the substrate.
    Type: Application
    Filed: June 26, 2019
    Publication date: December 30, 2021
    Applicants: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Fei Qi, Hao Yan, Zhiliang Jiang, Mingfang Wang, Yu Zhang
  • MASK FIXING APPARATUS, MASK COMPONENT AND RADIOTHERAPY DEVICE
    Publication number: 20210387021
    Abstract: A mask fixing apparatus, a mask component and a radiotherapy device are provided. The mask fixing apparatus includes: a frame, being configured to fix a mask, the frame being U-shaped having an inner boundary line and an outer boundary line, an opening of the frame fitting a neck of a patient, the inner boundary line of the frame being determined based on a periphery of a head of the patient, and the outer boundary line of the frame being determined based on a treatment cavity or an anti-collision cover in the treatment cavity; and a back-head support, being configured to support a back-head of the patient, and being connected with the frame to jointly carry the head of the patient, the inner surface of the back-head support fitting the back-head of the patient, and the outer surface of the back-head support being a curved surface having a preset curvature.
    Type: Application
    Filed: December 31, 2020
    Publication date: December 16, 2021
    Inventors: Hui LIU, Daliang LI, Hao YAN, Peng ZAN
  • METHOD FOR DESIGNING AN IMPELLER WITH A SMALL HUB-TIP RATIO AND A RIM-DRIVEN PUMP OBTAINED BY THE METHOD
    Publication number: 20210364005
    Abstract: A method for designing an impeller with a small hub-tip ratio includes the following steps: S1: obtaining an outer diameter D of the impeller with the small hub-tip ratio; S2: determining the number of blades and an airfoil of the blade of the impeller with the small hub-tip ratio; S3: obtaining a blade solidity sy at a rim of the impeller with the small hub-tip ratio and a blade solidity sg at a hub of the impeller with the small hub-tip ratio; S4: dividing the blades of the impeller with the small hub-tip ratio into m cylindrical sections in an equidistant manner, marking the cylindrical sections as 1-1, 2-2, . . . , m-m in sequence from the hub to the rim, and obtaining an airfoil setting angle ?L of each of the cylindrical sections; and S5: performing a correction on the value of the airfoil setting angle ?L in S4.
    Type: Application
    Filed: August 21, 2019
    Publication date: November 25, 2021
    Applicant: HEFEI UNIVERSITY OF TECHNOLOGY
    Inventors: Hao YAN, Qiang LI, Xiaozhen SU, Yu ZHANG, Liang CHEN, Liping CHAI, Haixia SHI
  • METHOD FOR RECOVERING ROOM-TYPE COAL PILLARS BY CEMENTED FILLING OF RESERVED ROADWAYS
    Publication number: 20210355826
    Abstract: Provided is a method for recovering room-type coal pillars by cemented filling of reserved roadways, which is especially suitable for safe and efficient recovery of left coal pillars in room-type mining faces in mining areas where the ecological system is fragile, such as in western China. In the method, by constructing reserved roadways in two adjacent rows of room-type goafs, excavating coal pillar roadways in room-type coal pillars, and finally interconnecting the reserved roadways with the coal pillar roadways to form a U-shaped working face, room-type left coal pillars are recovered. Thus, not only the workload of roadway excavation is reduced, but also the recovery ratio of the coal resources is maximized. The method provides a novel technical model for the recovery of room-type left coal pillars in mining areas, such as in western China.
    Type: Application
    Filed: September 20, 2018
    Publication date: November 18, 2021
    Inventors: Nan Zhou, Meng Li, Hao Yan, Jixiong Zhang, Hengfeng Liu
  • Structure assisted directed evolution of multivalent aptamers
    Patent number: 11168320
    Abstract: Provided herein are methods and systems for structure-assisted evolution of multivalent aptamers using a single stranded DNA or single-stranded RNA nanostructure as a structural support. Also provided herein are methods for constructing ssDNA or ssRNA nanostructures as structural supports suitable for structure-assisted evolution of multivalent aptamers.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: November 9, 2021
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventor: Hao Yan
  • PROTECTIVE FILM FOR SUBSTRATE, MANUFACTURING METHOD THEREOF, SUBSTRATE AND MANUFACTURING METHOD OF DISPLAY PANEL
    Publication number: 20210341650
    Abstract: The present disclosure provides a protective film for a substrate, a manufacturing method thereof, a substrate and a manufacturing method of a display panel. The substrate includes a plurality of panel regions correspondingly forming a plurality of display panels. Each of the panel regions has a first region corresponding to a bending region of the display panels. The protective film includes a entire film layer and a hollow portion, the size of the entire film layer matches the size of the substrate, and the hollow portion is for exposing the first region in each of the panel regions when the protective film is attached to the substrate.
    Type: Application
    Filed: September 7, 2018
    Publication date: November 4, 2021
    Inventors: Yu ZHANG, Hao YAN, Haitao YI, Zhenghong WANG, Zhiliang JIANG
  • FLEXIBLE DISPLAY PANEL
    Publication number: 20210331441
    Abstract: The present disclosure relates to a flexible display panel. The flexible display panel includes a flexible substrate and a protective film located on the flexible substrate. The protective film includes a plurality of grooves spaced apart from each other. The plurality of grooves includes at least one row of grooves. Positions of the grooves correspond to regions of the flexible substrate where display units are not formed.
    Type: Application
    Filed: March 13, 2019
    Publication date: October 28, 2021
    Inventors: Hao YAN, Yu ZHANG
  • DNA ORIGAMI NANOSTRUCTURES FOR TREATMENT OF ACUTE KIDNEY INJURY
    Publication number: 20210322453
    Abstract: Disclosed herein are methods of treating acute kidney injury. The method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M13 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.
    Type: Application
    Filed: April 23, 2021
    Publication date: October 21, 2021
    Inventors: Hao YAN, Dawei JIANG, Zhilei GE, Hyung-Jun IM, Christopher ENGLAND, Peng HUANG, Chunhai FAN, Weibo CAI
  • Dosage verification method for radiotherapy device, and radiotherapy device
    Patent number: 11147988
    Abstract: A dosage verification method for a radiotherapy device includes: acquiring reference optical field information about radioactive rays, wherein the reference optical field information includes the dosage distribution of a reference optical field; acquiring actual optical field information about the radioactive rays; comparing and analyzing the acquired actual optical field information about the radioactive rays and the acquired reference optical field information; and determining whether the actual optical field information is in a range of pre-set optical field information, wherein the pre-set optical field information is optical field information determined according to the reference optical field information.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: October 19, 2021
    Inventors: Jinsheng Li, Haifeng Liu, Hao Yan
  • METHOD AND APPARATUS FOR ADJUSTING POSITION, STORAGE MEDIUM, AND RADIOTHERAPY SYSTEM
    Publication number: 20210316159
    Abstract: A method for adjusting a position, including: acquiring a real-time position of a positioning marker preset at an affected part; acquiring a reference position of the positioning marker; and outputting position adjustment information, by means of a display and/or a voice, based on the real-time position and the reference position. The position adjustment information is configured to prompt a patient to adjust his/her position.
    Type: Application
    Filed: August 7, 2018
    Publication date: October 14, 2021
    Inventors: Hao YAN, Tianchang GOU, Jiuliang LI, Jinsheng LI
  • Radiation therapy apparatus and beam imaging method
    Patent number: 11135450
    Abstract: The present disclosure falls into the field of medical apparatus, and discloses a radiation therapy apparatus and a beam imaging method, wherein the radiation therapy apparatus includes: a treatment head including multiple radiation sources distributed on one side of a target region, radiation beams emitted by the multiple radiation sources intersecting in the target region, and a lesion being located within the target region; a beam detector used for receiving a radiation beams passing through the lesion and emitted by the radiation sources to acquire projection data of each radiation beam passing through the lesion, and generating a slice image of the lesion according to the acquired projection data; and a processor used for constructing an image of the lesion in the target region based on the slice image generated by the beam detector.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: October 5, 2021
    Inventors: Hao Yan, Jinsheng Li