Abstract: The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof.

Abstract: A wireless communication clock synchronized with a peer electronic device in the network is established at the first electronic device. Interruption signals are generated by the first electronic device synchronously with the peer accordingly. A clock value of a processor of the first electronic device at generating a last interruption signal is recorded by the first electronic device. A synchronization request including the clock value recorded is sent to the peer, to trigger adjusting, by the peer according to a difference between the clock value recorded by the first electronic device and a clock value recorded by the peer, a clock of a processor of the peer electronic device to be synchronized with a clock of the processor of the first electronic device. The clock value recorded by the peer electronic device is the clock value of the processor of the peer electronic device at generating a last interruption signal.

Abstract: Provided are a calibration method, device and storage medium of radiotherapy equipment. The calibration method of the radiotherapy equipment adopts an imaging body disposed within a preset distance range of an isocenter of radiotherapy equipment to perform error calibration on the radiotherapy equipment, and includes: imaging the imaging body through an imaging system to obtain an actual image of the imaging body; determining an image deviation between the actual image and a theoretical image of the imaging body, wherein the theoretical image is determined in advance based on a theoretical position of the imaging system and a spatial position of the imaging body in a rack; and determining a system error of imaging system based on the image deviation. Thus, the imaging system is calibrated without moving a treatment couch. The calibration accuracy of imaging system is not influenced by movement precision of treatment couch. The calibration accuracy is improved.

Abstract: A method for determining a CT system parameter: controlling a mould body to move between an X-ray source and a detection surface of a detector, and acquiring X-ray projections of the mould body during movement on the detection surface, wherein the mould body has a first plane and a second plane perpendicular to each other, and the first plane and the second plane are always perpendicular to the detection surface during the movement of the mould body; determining a first straight line and a second straight line according to the acquired X-ray projections; and determining an intersection point of the first straight line and the second straight line as a pedal coordinate of a focus of the X-ray source on the detection surface, a CT coordinate system parameter including the coordinates of the foot of the perpendicular.

Abstract: A method for tracking and irradiating a target using a radiotherapy apparatus, a device and a radiotherapy apparatus are provided. The radiotherapy apparatus includes a first ray source, a second ray source, and at least one detector. The method includes: moving the first ray source to a first location to emit a ray beam; receiving the ray beam emitted from the first ray source at the first location and generating first image data of a target according to the received ray beam, by the detector; and adjusting the second ray source according to the first image data to make the second ray source move to the first location and an emitted ray beam pass through the target, wherein a time taken for the second ray source to move to the first location is a positive integer multiple of a preset respiratory period of a patient.

Abstract: The present invention relates to a radiotherapy apparatus and a method for determining target positions using a radiotherapy apparatus, so as to accurately detect the motion of the tumor position.

Abstract: Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.

Abstract: Ultraspecific, programmable nucleic acid sensors capable of detecting and preferentially amplifying target DNA molecules comprising a particular SNP or mutation are provided. In some cases, the ultraspecific programmable nucleic acid sensors are useful for detecting SNP-containing DNA molecules indicative of cancer such as cell-free DNA circulating in the blood or indicative of organ transplant rejection Also provided are methods for construction of such ultraspecific nucleic acid sensors and methods for preferential amplification of target DNA molecules containing a mutation of interest, as well as testing systems for early cancer screening and routine monitoring of circulating cancer DNA using liquid biological samples such as serum, plasma, or saliva.

Abstract: The present disclosure relates to systems and methods for heat transfer and cooling in PET. The system may include a gantry including a gantry forming a detection tunnel; a detector mounted to the gantry, and positioned in a circumference of the detection tunnel; a heat transfer device thermally coupled with the detector and configured to transfer heat generated by the detector; and a cooling device thermally coupled to the heat transfer device, and configured to cool the heat transfer device.

Abstract: A method, a device and a storage medium for cleaning a memory are provided. The method includes that: a preset level corresponding to a detected hang state is determined; a cleaning mode corresponding to the preset level is determined; and an application program running in a memory is cleaned according to the cleaning mode.

Abstract: A dosage verification method for a radiotherapy device includes: acquiring reference optical field information about radioactive rays, wherein the reference optical field information includes the dosage distribution of a reference optical field; acquiring actual optical field information about the radioactive rays; comparing and analyzing the acquired actual optical field information about the radioactive rays and the acquired reference optical field information; and determining whether the actual optical field information is in a range of pre-set optical field information, wherein the pre-set optical field information is optical field information determined according to the reference optical field information.

Abstract: An apparatus for pre-loading a mechanical constant-resistance single prop includes a rhombic stretchable bracket, a screw rod, a first cylindrical sleeve ring, and a second cylindrical sleeve ring. The screw rod is connected to two opposite apex corners of the rhombic stretchable bracket. A tail end of the screw rod is fixedly connected to one apex corner of the rhombic stretchable bracket. An end head of the screw rod passes through another apex corner of the rhombic stretchable bracket. The remaining two opposite apex corners of the rhombic stretchable bracket are respectively fixedly connected to edges of the first cylindrical sleeve ring and the second cylindrical sleeve ring through connecting rods. The screw rod is threadedly connected to the apex corner of the rhombic stretchable bracket through which the screw rod passes. A method for pre-loading a mechanical constant-resistance single prop is also provided.

Abstract: In certain embodiments, the present invention provides a DNA nanostructure nanorobot comprising: a single stranded DNA scaffold strand of about 5,000 to 10,000 bases in length; a plurality of staple strands of DNA, wherein each staple strands are about 20 to 40 bases in length, wherein each staple strand has a unique sequence and is hybridized to a specific position on the DNA scaffold strand, wherein the plurality of staple strands hybridized to the DNA scaffold form a sheet having a top surface and a bottom surface; and one or more fastener strands of DNA, wherein the one or more fastener strands of DNA is capable of fastening the sheet into an origami structure.

Abstract: The present disclosure relates to systems and methods for heat transfer and cooling in PET. The system may include a gantry including a gantry forming a detection tunnel; a detector mounted to the gantry, and positioned in a circumference of the detection tunnel; a heat transfer device thermally coupled with the detector and configured to transfer heat generated by the detector; and a cooling device thermally coupled to the heat transfer device, and configured to cool the heat transfer device.

Abstract: The present disclosure falls into the field of medical apparatus, and discloses a radiation therapy apparatus and a beam imaging method, wherein the radiation therapy apparatus includes: a treatment head including multiple radiation sources distributed on one side of a target region, radiation beams emitted by the multiple radiation sources intersecting in the target region, and a lesion being located within the target region; a beam detector used for receiving a radiation beams passing through the lesion and emitted by the radiation sources to acquire projection data of each radiation beam passing through the lesion, and generating a slice image of the lesion according to the acquired projection data; and a processor used for constructing an image of the lesion in the target region based on the slice image generated by the beam detector.

Abstract: A time-to-digital converter includes N stages of converting circuits, where N2, and N is an integer. Each stage of the converting circuit includes a first delayer and an arbiter; an output end of the first delayer in each stage of the converting circuit outputs a delayed signal of the stage of the converting circuit; and the arbiter in each stage of the converting circuit receives a sampling clock and the delayed signal of the stage of the converting circuit, and compares the sampling clock with the delayed signal to obtain an output signal of the stage of the converting circuit. The first delayer in each stage of the converting circuit includes at least one first delay cell circuit with a first time unit. The first delayer in any stage of the converting circuit includes a less number of first delay cell circuits than the first delayer in a next stage of the converting circuit.

Abstract: Disclosed is a method for designing supporting parameters of a transition support for a mixed mining face of filling and fully-mechanized mining.

Abstract: Novel compositions and methods for engineering wireframe architectures and scaffolds of increasing complexity by creating gridiron-like DNA structures (FIG. 1). A series of four-arm junctions are used as vertices within a network of double-helical DNA fragments. Deliberate distortion of the junctions from their most relaxed conformations ensures that a scaffold strand can traverse through individual vertices in multiple directions. DNA gridirons, ranging from two-dimensional arrays with reconfigurability to multilayer and three-dimensional structures and curved objects, can be assembled according the methods presented herein.

Abstract: Provided are a method for tracking tumor location and a radiotherapy apparatus, relating to the field of medical equipment technology. The method is applied to a radiotherapy apparatus comprising a first detector and at least one radiation source, and comprises emitting, from the radiation source, ray beams having a predetermined intensity, the ray beams being partially scattered after passing through a body lesion; receiving, by the first detector, a portion of scattered ray beams to acquire scattering data of the lesion; determining a relative location relationship between the lesion and a target region according to the acquired scattering data; and adjusting at least one of the ray beam intensity, lesion location and target region location according to the determined relative location relationship, such that the lesion receives irradiation of the ray beams having an adjusted predetermined intensity at the target region location.

Abstract: Methods and devices are disclosed for delaying screen-on notification broadcasting. In one embodiment, a method for delaying screen-on notification broadcasting in a device comprises: detecting a display screen wakeup event for a display screen of the device, when the display screen wakeup event is detected and a current interface is a lock screen interface, intercepting a screen-on notification information broadcasted by an operating system of the device to applications running on the device, and when switching of the display screen from the lock screen interface into an unlocked interface after unlocking by a user is detected, sending the intercepted notification information to the applications.