Patents by Inventor Hao Yin

Hao Yin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9322040
    Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: April 26, 2016
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju
  • Patent number: 9315472
    Abstract: The present invention provides novel 1,3,5-triazinane-2,4,6-trione derivatives, such as compounds of any one of Formulae (I) and (II), and salts thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an siRNA, mRNA, or plasmid DNA). The present invention also provides methods and kits using the compositions for delivering an agent to a subject (e.g., to the liver, spleen, or lung of the subject) or cell and for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, liver diseases, and lung diseases.
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: April 19, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Yizhou Dong, Akinleye C. Alabi, Hao Yin, Joseph R. Dorkin, Delai Chen, Robert S. Langer, Daniel Griffith Anderson, Ahmed A. Eltoukhy
  • Publication number: 20160068495
    Abstract: The present invention provides a compound of Formula (I) and a salt thereof, wherein, m is an integer of 2 to 7, and R is independently at least one selected from the group consisting of hydrogen and C1-C20 alkyl. The compound promotes apoptosis in cancer cell and inhibits its growth. The present invention also provides a pharmaceutical composition which comprises the compound of Formula (I), a salt thereof and a pharmaceutically acceptable carrier. The present invention further provides a method for production of the pharmaceutical composition used for treating cancer.
    Type: Application
    Filed: January 14, 2015
    Publication date: March 10, 2016
    Applicant: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Jui-I Chao, Su-Pei Wang, Chinpiao Chen, Kai-Hao Yin, Jinn-Moon Yang, Ya-Hui Wu
  • Patent number: 9200301
    Abstract: The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: December 1, 2015
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Lijuan Long, Xinpeng Tian, Jie Li, Xiongming Luo, Zhenxiong Qi, Tuan Yin, Hao Yin, Jian Yang
  • Publication number: 20150158809
    Abstract: Methods of preparing carbamate prodrugs of amine-containing drugs are provided. Carbonates useful in the synthesis of the carbamate prodrugs are also provided.
    Type: Application
    Filed: February 25, 2014
    Publication date: June 11, 2015
    Applicant: XENOPORT, INC.
    Inventors: Huan Wang, Peng Liu, Qunying Dai, Hao Yin, Stephen P. Raillard
  • Publication number: 20150142443
    Abstract: The present disclosure relates to a syntax parsing apparatus based on syntax preprocessing and a method thereof. In specific, the present disclosure parses syntaxes that can be parsed by rules and patterns without ambiguity by syntax parsing preprocessing, draws all possible syntax parsing results by applying syntax rules based on a result of syntax parsing preprocessing in which ambiguity is partially resolved, and resolves structural ambiguity by applying a statistic syntax parsing model learned from a syntax tree attachment learning corpus so as to reduce ambiguity in rule-based syntax parsing and to resolve ambiguity by a statistics-based scheme so that parsing correctness and processing efficiency in a syntax parsing method can be enhanced.
    Type: Application
    Filed: August 30, 2013
    Publication date: May 21, 2015
    Inventors: Young Sook Hwang, Chang Hao Yin
  • Publication number: 20140329884
    Abstract: The present invention provides novel 1,3,5-triazinane-2,4,6-trione derivatives, such as compounds of any one of Formulae (I) and (II), and salts thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an siRNA, mRNA, or plasmid DNA). The present invention also provides methods and kits using the compositions for delivering an agent to a subject (e.g., to the liver, spleen, or lung of the subject) or cell and for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, liver diseases, and lung diseases.
    Type: Application
    Filed: May 1, 2014
    Publication date: November 6, 2014
    Inventors: Yizhou Dong, Akinleye C. Alabi, Hao Yin, Joseph R. Dorkin, Delai Chen, Robert S. Langer, Daniel Griffith Anderson, Ahmed A. Eltoukhy
  • Publication number: 20140303955
    Abstract: The present disclosure relates to an apparatus and a method for recognizing an idiomatic expression using phrase alignment of a bilingual parallel corpus, and more particularly, to an apparatus and a method for recognizing an idiomatic expression using phrase alignment of a parallel corpus which extract a candidate idiomatic expression using phrase alignment information of a bilingual parallel corpus and measure an idiomatic expression index for every extracted candidate idiomatic expression to recognize the candidate idiomatic expression as an idiomatic expression to resolve errors in measuring a translational entropy of a word and extracting a representative translated word of the word and improve the accuracy of the idiomatic expression recognition.
    Type: Application
    Filed: May 25, 2011
    Publication date: October 9, 2014
    Applicant: SK PLANET CO., LTD.
    Inventors: Sang-Bum Kim, Chang Hao Yin, Young Sook Hwang, Hae Chang Rim, Hyoung Gyu Lee
  • Publication number: 20140243544
    Abstract: Methods of preparing carbamate prodrugs of amine-containing drugs are provided. Carbonates useful in the synthesis of the carbamate prodrugs are also provided.
    Type: Application
    Filed: February 25, 2014
    Publication date: August 28, 2014
    Applicant: XENOPORT, INC.
    Inventors: Huan Wang, Peng Liu, Qunying Dai, Hao Yin, Stephen P. Raillard
  • Patent number: 8818792
    Abstract: An apparatus and a method for constructing a verb phrase translation pattern using a bilingual parallel corpus. Each of the apparatus or method recognizes a predicate and an argument using a syntax analysis result and a word alignment result of a source sentence from a plurality of bilingual parallel corpus, extracts a translation pattern candidate and an occurrence frequency using the recognized predicate and argument, and then generates a basic verb phrase translation pattern by verifying the translation pattern candidate, and generalizes the generated basic verb phrase translation pattern to generate a general verb phrase pattern so as to be applied to various language pairs and minimize an error in the verb phrase translation pattern and determine an appropriate generalization level using a co-occurrence frequency of a predicate and an argument of the verb phrase translation pattern and a translation probability of the predicate.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: August 26, 2014
    Assignee: SK Planet Co., Ltd.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Hae Chang Rim, Joo Young Lee
  • Patent number: 8759523
    Abstract: The present invention relates to a process comprising the step of dehydrating a compound of Formula (I): with a suitable dehydrating reagent to form a compound of Formula (II): wherein R1-R7 are as defined herein. Compounds of Formula (II) have shown promise as intermediates to compounds useful for treating bacterial infections.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: June 24, 2014
    Assignee: Glaxo Group Limited
    Inventors: Joseph Sisko, Douglas Mans, Hao Yin
  • Publication number: 20140154929
    Abstract: The present application relates to an electrical connector, the electrical connector is formed with a receiving space having an opening opened upwardly, the electrical connector comprises an insulative body, a plurality of terminals and a metal shell. The terminals are fixed to the insulative body. The metal shell is mounted to the insulative body. The metal shell comprises a resilient piece, the resilient piece protrudedly extends toward the receiving space, a distal end of the resilient piece comprises a first tab and a second tab, the first tab and the second tab extend downwardly respectively, the first tab is offset toward inside of the receiving space relative to the second tab, and an end edge of the second tab is lower than an end edge of the first tab.
    Type: Application
    Filed: May 29, 2013
    Publication date: June 5, 2014
    Inventors: Hao YIN, Chun-Guang Li
  • Publication number: 20140140881
    Abstract: The present invention relates to a method 931 for producing a solid element, which comprises the thermoelectrically active material beta-Zn4Sb3. The method utilizes that is possible to directly synthesize and press pellets of Zn4Sb3 starting from powders of Zn and Sb, by mixing 930 powders of Zn and Sb so as to obtain a mixed powder comprising elemental zinc and elemental antimony, placing 932 the mixed powder in a container and simultaneously applying 936 a pulsed current, such as to heat up the powders, and applying 938 a pressure such as to compact the powder mix. The gist of the invention might be seen as exploiting the basic insight, that the cumbersome and time- and energy consuming steps of synthesis and pressing of Zn and Sb, so as to achieve a solid element comprising Zn4Sb3, can be combined into a single step where the synthesis and pressing is effected simultaneously.
    Type: Application
    Filed: July 16, 2012
    Publication date: May 22, 2014
    Applicant: AARHUS UNIVERSITET
    Inventors: Bo Brummerstedt Iversen, Mogens Christensen, Hao Yin
  • Publication number: 20140012564
    Abstract: Disclosed all an apparatus and a method for constructing a verb phrase translation pattern using a bilingual parallel corpus which recognizes a predicate and an argument using a syntax analysis result and a word alignment result of a source sentence from a plurality of bilingual parallel corpus, extracts a translation pattern candidate and an occurrence frequency using the recognized predicate and argument, and then generates a basic verb phrase translation pattern by verifying the translation pattern candidate, and generalizes the generated basic verb phrase translation pattern to generate a general verb phrase pattern so as to be applied to various language pairs and minimize an error in the verb phrase translation pattern and determine an appropriate generalization level using a co-occurrence frequency of a predicate and an argument of the verb phrase translation pattern and a translation probability of the predicate.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 9, 2014
    Applicant: SK PLANET CO., LTD.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Hae Chang Rim, Joo Young Lee
  • Patent number: 8543376
    Abstract: Disclosed are a joint decoding apparatus and a joint decoding method that joins a tokenization process and a translation process. More particularly, the present disclosure can generate all available candidate tokens, reduce translation errors, and obtain an optimal translation result by jointly conducting a decoding by simultaneously conducting the tokenization process and the translation process for an input character sequence while decoding.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: September 24, 2013
    Assignee: SK Planet Co., Ltd
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Xinyan Xiao, Yang Liu, Qun Liu, Shouxun Lin
  • Publication number: 20130230890
    Abstract: The invention discloses a Pseudonocardia sp. and a method for preparing Deoxynyboquinone by utilizing the same. Pseudonocardia sp. SCSIO 01299 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011255 on Jul. 18, 2011. The Pseudonocardia sp. SCSIO 01299 can produce antibiotic Deoxynyboquinone, so that the Pseudonocardia sp. SCSIO 01299 can be utilized for preparing Deoxynyboquinone and a new way is provided for producing antibiotic Deoxynyboquinone with anti-tumor activity.
    Type: Application
    Filed: September 1, 2011
    Publication date: September 5, 2013
    Applicant: South China Sea Institute of Oceanology, Chinese Academy of Sciences
    Inventors: Si Zhang, Changsheng Zhang, Xinpeng Tian, Sumei Li, Wenjun Zhang, Haibo Zhang, Guangtao Zhang, Hao Yin, Jianhua Ju
  • Publication number: 20130226556
    Abstract: The present invention relates to statistical machine translation, and provides a machine translation device and a machine translation method that acquire a creation probability for a target language from a single corpus while extracting respective conversion probabilities by extracting syntax conversion knowledge and word translation knowledge from a parallel corpus, model a weighted translation model by allowing each of the conversion knowledge and each of the probabilities to learn using a translation model learning device, and generate a target sentence through decoding processes of a syntax converter and a word translator by applying the translation model to a source sentence input in real time, thereby resolving disadvantages of the existing phrase-based SMT and syntax-based SMT and combining advantages thereof.
    Type: Application
    Filed: July 20, 2011
    Publication date: August 29, 2013
    Applicant: SK Planet Co., Ltd.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Yeon Su Lee, Seong Wook Lee, Hae Chang Rim
  • Publication number: 20130158975
    Abstract: The present invention relates to the use of a plurality of dependency trees in tree-based statistical machine translation and proposes a dependency forest to effectively process the plurality of dependency trees. The present invention can improve a translation capability by generating a translation rule and a dependency language model by using the dependency forest and applying the generated translation rule and dependency language model when a source language text is converted to a target language text.
    Type: Application
    Filed: May 31, 2011
    Publication date: June 20, 2013
    Applicant: SK PLANET CO., LTD.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Shouxun Lin, Zhaopeng Tu, Yang Liu, Qun Liu, Chang Hao Yin
  • Publication number: 20130132064
    Abstract: Disclosed are a joint decoding apparatus and a joint decoding method that joins a tokenization process and a translation process. More particularly, the present disclosure can generate all available candidate tokens, reduce translation errors, and obtain an optimal translation result by jointly conducting a decoding by simultaneously conducting the tokenization process and the translation process for an input character sequence while decoding.
    Type: Application
    Filed: May 25, 2011
    Publication date: May 23, 2013
    Applicant: SK PLANET CO., LTD.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Xinyan Xiao, Yang Liu, Qun Liu, Shouxun Lin
  • Publication number: 20130117010
    Abstract: Disclosure relates to a statistical machine translation field, and more particularly to a method and a device for filtering a translation rule and generating a target word in a hierarchical phrase-based statistical machine translation. The method and device filters a translation rule using a relaxed-well-formed dependency structure and generates a target word by referring to a head word of a source word in a hierarchical phrase-based statistical machine translation. The disclosure improves a translation performance while reducing a number of translation rules, in comparison with a hierarchical phrase-based original translation rule table.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 9, 2013
    Applicant: SK PLANET CO., LTD.
    Inventors: Young Sook Hwang, Sang-Bum Kim, Chang Hao Yin, Zhiyang Wang, Qun Liu, Yajuan Lv