Patents by Inventor Harold Walder

Harold Walder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9023249
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: May 5, 2015
    Assignees: Immunolight, LLC, Duke University
    Inventors: Zakaryae Fathi, James Clayton, Harold Walder, Frederic A. Bourke, Jr., Ian Stanton, Jennifer Ayres, Joshua T. Stecher, Michael Therien, Eric Toone, Dave Gooden, Mark Dewhirst, Joseph A. Herbert, Diane Fels, Katherine S. Hansen
  • Publication number: 20140323946
    Abstract: A system and method for light stimulation within a medium. The system has a reduced-voltage x-ray source configured to generate x-rays from a peak applied cathode voltage at or below 105 kVp, and a plurality of energy-emitting particles in the medium which, upon radiation from the x-ray source, radiate at a first lower energy than the x-ray source to interact with at least one photoactivatable agent in the medium. The method introduces the plurality of energy-emitting particles into the medium, radiates the energy-emitting particles in the medium with x-rays generated from a peak applied cathode voltage at or below 105 kVp; and emits a lower energy than the x-ray source to interact with the medium or with at least one photoactivatable agent in the medium.
    Type: Application
    Filed: July 9, 2012
    Publication date: October 30, 2014
    Applicants: DUKE UNIVERSITY, IMMUNOLIGHT, LLC
    Inventors: Frederic A. Bourke, JR., Harold Walder, Zakaryae Fathi, Michael J. Therien, Mark W. Dewhirst, Ian N. Stanton, Jennifer Ann Ayres, Diane Renee Fels, Joseph A. Herbert
  • Publication number: 20140272030
    Abstract: A method and a system for producing a change in a medium. The method places in a vicinity of the medium an energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The energy modulation agent has a normal predominant emission of radiation in a first wavelength range outside of a second wavelength range (WR2) known to produce the change, but under exposure to the applied initiation energy produces the change. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: IMMUNOLIGHT, LLC.
    Inventors: Frederic Avery Bourke, JR., Zakaryae Fathi, Harold Walder, Wayne F. Beyer, JR.
  • Publication number: 20140243934
    Abstract: Products, compositions, systems, and methods for modifying a target structure. The methods may be performed in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength ?1, to generate a second wavelength ?2 of radiation having a higher energy than the first wavelength ?1. The methods may further be performed by application of an initiation energy to activate a photoactivatable agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 28, 2014
    Applicants: DUKE UNIVERSITY, IMMUNOLIGHT, LLC
    Inventors: Tuan VO-DINH, Jonathan P. Scaffidi, Venkata Gopal Reddy Chada, Benoit Lauly, Yan Zhang, Molly K. Gregas, Ian Nicholas Stanton, Joshua T. Stecher, Michael J. Therien, Frederic A. Bourke, JR., Harold Walder, Zak Fathi, Jennifer A. Ayres, Zhenyuan Zhang, Joseph H. Simmons, Stephen John Norton
  • Publication number: 20120089180
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Application
    Filed: May 6, 2011
    Publication date: April 12, 2012
    Applicants: Duke University, Immunolight, LLC
    Inventors: Zakaryae Fathi, James Clayton, Harold Walder, Frederic A. Bourke, JR., Ian Stanton, Jennifer Ayres, Joshua T. Stecher, Michael Therien, Eric Toone, Dave Gooden, Mark Dewhirst, Joseph A. Herbert, Diane Fels, Katherine S. Hansen
  • Publication number: 20120064134
    Abstract: A light emitting composition including first color emitters and second color emitters. The first color emitters are configured to emit, upon exposure to an energy source, visible light at a target color in response to absorption of energy across a first band of wavelengths. The second color emitters are configured to emit, upon exposure to the energy source, visible light at the target color in response to absorption of energy across a second band of wavelengths. The light intensity observable at the target color is enhanced relative to reflected white light without emission from the first and second color emitters. The light emitting composition can be a part of a paint, an ink, a fabric, a thread, a road sign, a highway marking, an automobile, a boat, a plane, a reflector, a building product, a concrete product, an epoxy product, a jewelry product, colored contact lens, a candle product, a rubber product, a plastic product, or other colored surface.
    Type: Application
    Filed: August 5, 2011
    Publication date: March 15, 2012
    Applicant: Immunolight, LLC
    Inventors: Frederic J. Bourke, JR., Harold Walder
  • Publication number: 20110021970
    Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength ?1, to generate a second wavelength ?2 of radiation having a higher energy than the first wavelength ?1.
    Type: Application
    Filed: April 21, 2010
    Publication date: January 27, 2011
    Applicants: Duke University, Immunolight, LLC
    Inventors: Tuan VO-DINH, Jonathan P. SCAFFIDI, Venkata Gopal Reddy CHADA, Benoit LAULY, Yan ZHANG, Molly K. GREGAS, Ian N. STANTON, Joshua T. STECHER, Michael J. THERIEN, Frederic A. BOURKE, JR., Harold WALDER, Zak FATHI, Jennifer A. AYRES, Zhenyuan ZHANG, Joseph H. SIMMONS, Stephen John NORTON
  • Publication number: 20100016783
    Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.
    Type: Application
    Filed: April 3, 2009
    Publication date: January 21, 2010
    Applicants: Duke University, Immunolight, LLC
    Inventors: Frederic J. BOURKE, JR., Tuan Vo-Dinh, Harold Walder