Abstract: A magnetic resonance (MR) surgery system facilitates surgery with a focussed ultrasound transducer that selectively destroys tissue in a region within a subject. The focussed energy transducer dissipates energy at a focal point within the region of tissue to be destroyed. A non-magnetic positioning device having a vertical dimension small enough to fit easily within the bore of an MR magnet moves an energy transducer in a limited vertical space. The positioning device employs a plurality of hydraulic positioners and an inclined plane to position the ultrasound focal point under the control of an operator. An MR imaging system employing a temperature sensitive pulse sequence creates an image of the tissue and the region being heated to allow the operator to adjust the position of the ultrasonic transducer so as to direct ultrasonic energy to the appropriate location.

Abstract: A magnetic resonance surgery system facilitates performance of surgery with a focussed ultrasound transducer that selectively destroys tissue in a region within a subject. The focussed ultrasound transducer dissipates ultrasonic energy at a focal point within the region of tissue to be destroyed. A number of hydraulic positioners position the focal point under the control of a surgeon. A magnetic resonance imaging system employing a temperature sensitive pulse sequence creates an image of the tissue and the region being heated to allow the surgeon to adjust the position of the ultrasonic transducer so as to direct ultrasonic energy to the appropriate location.

Abstract: A method for providing a volumetrically-rendered projection image using reverse ray casting, uses the steps of: acquiring, from an object volume of interest, a set of data sampled from each volume element (voxel) therein responsive to a selected characteristic of that object volume; storing the data for each object voxel in a corresponding data volume element; scanning sequentially through each data voxel within the data volume corresponding to the object volume of interest; projecting each scanned data voxel to an image plane, at a solid angle determined from the solid angle at which the object volume is viewed; storing a value for each image plane pixel, responsive to a selected criteria, from the values of all projected data voxel values impingent upon that image plane pixel; and then scaling the dimensions of each image plane pixel responsive to the dimensions of the corresponding object volume shape, and the involved projection solid angle, to correct for anisotropy.

Abstract: A three dimensional image of a human brain or other body structure is constructed using a single flow sensitive data array and a flow insensitive data array to generate the contrasts necessary to differentiate among stationary tissues and also between stationary tissues and flowing blood. A plurality of data points from this combined image data are identified to tissue types and used to segregate the remaining data by using a nearest neighbor process in which each data value takes the tissue type of its nearest neighbor data point.

Abstract: An NMR system performs in vivo localized NMR spectroscopy. A two-dimensional selective RF excitation pulse is used to localize to a cylindrical region of interest, and either phase encoding or slice selective inversion is used to localize to a disk in the cylindrical region of interest. The two-dimensional selective RF excitation is performed in a series of pulse sequences rather than a single pulse sequence, and the resulting series of acquired NMR signals are summed together to substantially cancel signal conributions from outside the cylindrical region of interest.

Abstract: In order to display the surfaces of internal structures within a solid body from non-intrusively acquired data sets, it is useful to segment the data sets into the internal structures of interest before searching for the surfaces of such structures. To accomplish this, a data segmentation system uses a plurality of sample data points to construct a statistical probability distribution for a plurality of internal structures. Using these probability distributions, each data point is labeled with the most likely structure identification. Searching the thus-segmented data points for surfaces is considerably faster than is possible with the entire data set and produces surface renditions with fewer anomalies and errors. If the solid body is a human head, and nuclear magnetic resonance (NMR) is used to obtain two data sets corresponding to the two NMR echoes, then the probability distribution is bivariate and the two echoes can be plotted against each other to assist in identifying tissue clusters.

Abstract: In a method and apparatus for detecting and displaying arbitrary interior surfaces of a three-dimensional body from a regular array of values of at least one physical property in the interior of the body, the physical property measurements are made with systems such as computerized tomographic x-ray imaging, or magnetic resonance imaging. A recursive algorithm starts with a seed voxel in the surface of interest and continues to all adjacent voxels having a common face which is penetrated by the surface of interest. The common surface penetrations are derived from a look-up table which lists the adjacent voxels having a common penetrated face for each voxel index. The voxel index, in turn, is the string of binary digits representing the voxel vertices whose vertex values exceed the surface value of the surface of interest.

Abstract: A substantially continuous image, recording motion of a portion of a sample, is provided by first NMR exciting, through use of a rotating-gradient (.rho.) pulse signal, a relatively narrow cylindrical region, typically with diameter less than 1 inch, of magnetization intersecting the sample to be imaged and then acquiring the NMR response signal thus excited, in the presence of a readout gradient oriented along the length of the cylindrical excitation beam and establishing position thereon. A Fourier transformation of the acquired data allows display of a real-time record of the profile of the sample along the axis of the cylindrical probe beam. The cylinder-beam axis can be oriented in an arbitrary direction by proper mixing of the excitation and readout gradient fields; use of three orthogonal gradients in a Cartesian coordinate system is presently preferred.

Abstract: Arbitrary interior surfaces of a three-dimensional body are displayed from a regular array of values of at least one physical property in the interior of the body. The physical property measurements may be made with systems such as computerized tomographic x-ray, or magnetic resonance imaging. Highly parallel circuits and a highly parallel architecture permit generation of surface views in real time, i.e., sufficiently fast to support ongoing procedures such as surgical operations. These parallel circuits, realizable on large scale integrated circuit chips, perform surface normal calculations, linear interpolations and signal comparisons in simultaneously operating circuit paths which are asynchronously enabled when input data appear.

Abstract: A method and apparatus for displaying arbitrary cross-sectional views of a three-dimensional body from a regular array of values of at least one physical property in the interior of the body includes making physical property measurements with such systems as computerized tomographic x-ray systems, or magnetic resonance imaging systems. Cut planes are defined by the user as displacement from, and rotations from, an arbitrary coordinate origin in the data space. An initial plane of pixel positions of arbitrary density is displaced and rotated to correspond to the cut plane. The values for the physical property at the pixel positions are interpolated from the surrounding measurements of actual values. Cross-sectional images are thereby supplied interactively in real time to support, for example, ongoing surgical procedures.

Abstract: A method for simultaneously obtaining a three-dimensional nuclear magnetic resonance (NMR) angiographic image of moving spins associated with fluid flow in a region of a living organism sample, and a three-dimensional NMR image of stationary tissue in the same sample region, by immersing the sample in a main static magnetic field; nutating, in an excitation subsequence of each of a plurality of NMR sequences, the nuclear spins and the generating a flow-encoding magnetic field gradient selected to cause a resulting NMR response echo signal from the spin of a moving nucleus to be different from the NMR response echo signal from the spin of a substantially stationary nucleus.

Abstract: A count is kept of the number of surfaces traversed, in a variety of three-dimensional imaging systems which are particularly advantageous for use in medical applications based upon data generated by magnetic resonance imaging systems and computerized axial tomographic imaging systems. The system is particularly advantageous in a surgical workstation for planning a wide variety of operative procedures. Surfaces may be selected and displayed simultaneously so as to provide the viewer with a significantly improved knowledge of the relationship of various internal body structures.

Abstract: A metod for providing a three-dimensional nuclear magnetic resonance (NMR) flow-contrast angiograph of fluid flowing substantially only in a predetermined direction, with suppression of stationary material surrounding the fluid, uses the steps of: acquiring a first set of image data from NMR responses generated from a volume-to-be-imaged by a three-dimensional volume imaging sequence preceded by a saturation portion saturing nuclear spins in a volume adjacent to, and in the direction from which the desired flow will enter, the volume-to-be-imaged; acquiring a second set of image data from other NMR responses generated by the same volume imaging sequence, but devoid of any preceding saturating portion; and subtracting one of the first and second data sets from the other to generate a difference data set from which a final image is displayed. Advantageously, a 3DET volume imaging sequence is used, with bipolar flow-compensation used along both axes of flow encodation.

Abstract: A dual pipeline architecture for a system for preprocessing image data gathered from such systems as magnetic resonance imaging and computer axial tomography scanners. In one simultaneously operable dual pipeline, normal vectors are computed for each voxel element in accordance with the dividing cubes vector generation system. In another pipeline, circuitry is provided for generating surface identification indicia which are associated with unit normal vectors produced by the former pipeline. Data are supplied to a graphics processor for the production of shaded two-dimensional images representative of three-dimensional surfaces from various view angles. The system is particularly useful in medical diagnostic applications and is particularly useful in planning surgical procedures.

Abstract: An apparatus and method for determining connected substructures within a body is disclosed. The system and method are particularly advantageous for use in medical diagnostic imaging applications. In particular, three dimensional regions exhibiting the same tissue type are similarly labeled. The system and method of the present invention is operable in any situation in which three dimensional signal patterns representing the value of one or more physical properties associated with the substructures within a body at regularly spaced grid locations within the body are presented. A subset of the original data may then be provided to a display processor, particularly one employing gradient normal shading for display of three dimensional images.

Abstract: An apparatus and method for determining connected substructures within a body is disclosed. The system and method are particularly advantageous for use in medical diagnostic imaging applications. In particular, three dimensional regions exhibiting the same tissue type are similarly labeled. Using the label information together with a seed location located in the substructure of interest, all similarly labeled connected data points are determined. The system and method of the present invention is operable in any situation in which three dimensional signal patterns representing the value of one or more physical properties associated with the substructures within a body at regularly grid locations within the body are presented. A subset of the original data is then provided to a display processor particularly one employing gradient normal shading for display of three dimensional images.

Abstract: A method and apparatus for displaying three dimensional surface images includes the utilization of a case table for rapid retrieval of surface approximation information. Eight cubically adjacent data points associated with a given voxel element are compared with a predetermined threshold value or range to generate an eight bit vector. This eight bit vector is employed to rapidly produce vector lists of approximating surfaces. A non-linear interpolation operation is performed so as to more closely approximate the desired surface and to provide more accurate representations of vectors normal to the desired surface. The accurate representation of these normal directions provides means for accurately representing shading information on a display screen. The method and apparatus of the present invention are particularly useful for the display of medical images both from X-ray generated data and from data generated from various other sources including magnetic resonance imaging and positron emission tomography.

Abstract: A system for displaying three dimensional surface structures employs the analysis of voxel elements defined by eight cubically adjacent grid locations which are associated with at least one physical property defined throughout a three dimensional body. The physical property measurements may be made with such systems as computerized tomographic x-ray systems, or magnetic resonance imaging devices. Surface structures are defined by a user selected threshhold value such as distinct values for skin and bone in medical diagnostic applications. Selected voxels are subdivided and means are provided for generating signal values associated with intermediate additional grid locations. Means are also provided for generating surface normal vectors associated with these grid locations.

Abstract: A method and apparatus for displaying three dimensional surface images includes the utilization of a case table for rapid retrieval of surface approximation information. Eight cubically adjacent data points associated with a given voxel element are compared with a predetermined threshold value or range to generate an eight bit vector. This eight bit vector is employed to rapidly produce vector lists of approximating surfaces. An interpolation operation is performed so as to more closely approximate the desired surface and to provide more accurate representations of vectors normal to the desired surface. The accurate representation of these normal directions provides means for accurately representing shading information on a display screen. The method and apparatus of the present invention are particularly useful for the display of medical images both, from x-ray generated data and from data generated from various other sources including magnetic resonance imaging and positron emission tomography.

Abstract: Dielectrically isolated, thin single crystal films of semiconductor material suitable for integrated circuit applications and preparation thereof by solid state zone recrystallization of a polycrystalline layer of the semiconductor material are disclosed.