Abstract: A method includes collecting operational data from a system, segregating the data into a first component comprising one or more service quality anomalies and a second component comprising one or more network-based events, correlating the first component and the second component to determine whether the one or more network-based events have an impact on service quality, and prioritizing a resolution of the network-based events that have an impact on service quality.

Abstract: Systems and methods for managing and/or exchanging aviation records are provided. One example aspect is directed to a method that includes receiving, at one or more processors, an aviation record in a first format from a first computing system. The method includes performing, at the one more processors, a quality assurance procedure on the aviation record in the first format based on historical data. The method includes determining, at the one or more processors, whether the aviation record in the first format is valid based on the quality assurance procedure. The method includes selectively translating, at the one or more processors, the aviation record into a standardized format based on whether the aviation record in the first format is valid. The method includes storing, at the one or more processors, the aviation record in the standardized format if the aviation record in the first format is valid.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to coordinate node level adaptations. An example apparatus includes an adaptation support determiner to determine if an adaptation in an adaptation message is supported by a first device, an extractor to, in response to the determination that the adaptation in the adaptation message is supported by the first device, calculate a start-time for the first device based on (a) a transit duration of the adaptation message, (b) an execution duration of the adaptation in the adaptation message, and (c) a timestamp of when the second device sent the adaptation message, and an initiate a timer value for the first device and the second device, the timer value being a function of the start-time. The example apparatus further includes an installer to, in response to the timer value satisfying a threshold, execute the adaptation to reduce disruptions in the CPS.

Abstract: Disclosed are systems and methods for conducting an open conversation user interface and more particularly, to a channel-agnostic user interface experience which can utilize automated background intelligence to simplify the exchange between a software system or member service representative (MSR) and a member, and avoids the need for web-based free form inputs.

Abstract: Inorganic infrared attenuation agent blends have been developed to improve the thermal insulation properties of polymeric foams such as polystyrene low density foams. The inorganic infrared attenuation agent blends can include two or more metal oxides such as silicon dioxide, manganese (IV) oxide, iron (III) oxide, magnesium oxide, bismuth (III) oxide, cobalt oxide, zirconium (IV) oxide, molybdenum (III) oxide, titanium oxide, and calcium oxide. In some preferred embodiments, the inorganic infrared attenuation agent blends can include four or more of these metal oxides.

Abstract: The invention provides compositions, methods and treatment regimens for treating cancer comprising periodic subcutaneous administration of the fusion protein of SEQ ID NO:1 to a cancer patient resulting in enhanced activation of CD8+ T-cells with minimal effects on regulatory T cell (Treg) expansion and providing enhanced anti-tumor efficacy while also mitigating T cell inactivation/exhaustion.

Abstract: A capsule to store and deliver lyophilized reagents is described. The lyophilized reagent capsule is configured to store a lyophilized reagent for at least five days, and is further configured to deliver a lyophilized reagent to a biological sample. The capsule includes a top, a bottom, and a lyophilized reagent. A method for delivering the lyophilized reagent via the capsule and without the use of pipettes to deliver the lyophilized reagents is described. The capsule may be part of a lyophilized reagent capsule kit.

Abstract: A valve leaflet connecting device includes: a base; and first and second followers extending from the base. A first arm extends from the first follower in a direction away from the second follower and away from the base to define an acute angle between the first follower and first arm for capturing a first leaflet there between.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: A method includes detecting, with a sensor, a gaze of an occupant of a vehicle. The gaze is directed to at least one vehicle displays. The method also includes determining, with a controller circuit in communication with the sensor, whether one or more features presented on the at vehicle displays are partially obstructed from a view of the occupant. When the one or more features presented on vehicle displays are partially obstructed from the view of the occupant, the controller circuit adjusts a presentation of at least one partially obstructed features to be viewable by the occupant.

Abstract: A glass laminate for an architectural element has a glass substrate coupled to the architectural element and defines a primary surface facing away from the architectural element. A phase-separable glass cladding is coupled to the primary surface. The cladding has an interconnected matrix with a first phase composition and a second phase that has a second phase composition different than the first phase composition. The second phase is distributed throughout the interconnected matrix. A copper phase is distributed within the interconnected matrix. The glass cladding has an antimicrobial log kill rate greater than about 4 as measured by an EPA Copper Test Protocol.

Abstract: Various methods and systems are provided for a flexible, lightweight, low-cost radio frequency (RF) coil array of a magnetic resonance imaging (MRI) system. In one example, a posterior RF coil assembly for a MRI system includes an RF coil array including a plurality of RF coils and a deformable material housing the plurality of RF coils, each RF coil comprising a loop portion of distributed capacitance wire conductors and a coupling electronics unit coupled to each of the plurality of RF coils.

Abstract: Disclosed herein are methods and compositions related to single chain antibody fragments which specifically bind sialyl-Tn epitope of tumor-associated glycoprotein 72 (TAG-72).

Abstract: An accelerator system is implemented on an expansion card comprising a printed circuit board having (a) one or more graphics processing units (GPUs), (b) two or more associated memory banks (logically or physically partitioned), (c) a specialized controller, and (d) a local bus providing signal coupling compatible with the PCI industry standards. The controller handles most of the primitive operations to set up and control GPU computation. Thus, the computer's central processing unit (CPU) can be dedicated to other tasks. In this case a few controls (simulation start and stop signals from the CPU and the simulation completion signal back to CPU), GPU programs and input/output data are exchanged between CPU and the expansion card. Moreover, since on every time step of the simulation the results from the previous time step are used but not changed, the results are preferably transferred back to CPU in parallel with the computation.