Abstract: A server system communicating with a personal digital assistant (PDA), and a communication method thereof. In a system including a server system for generating and storing files to be distributed to a plurality of users, a data transceiver connected to the server system, and the PDA connected to the data transceiver, for transmitting and receiving the data of the server system, the server system includes: a data portion for storing all files; a selector for selecting files to be downloaded to the PDA from among the files provided by the data portion, according to the command of a user; a file storage portion for storing the files selected by the selector; and a controller for classifying the files selected by the selector according to users, storing the files by user in different directories of the file storage portion, and when a user wishes, downloading only files stored in the user directory of the file storage portion to the user's PDA.

Abstract: Methods are described whereby vertebrate skin, hair, wool or fur may be lightened, or darkened, in color by administration of a substance, e.g., peptide, antibody, antibody fragment or DNA sequence encoding a peptide, that modulates the protein kinase C-beta-mediated activation of tyrosinase, the rate-limiting enzyme in melanogenesis.