Patents by Inventor Henri Sebag

Henri Sebag has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5198470
    Abstract: The invention relates to a lipid compound of formula (I): ##STR1## where R.sub.1 denotes a C.sub.11 to C.sub.21 alkyl or alkenyl radical and R.sub.2 denotes a linear or branched C.sub.8 to C.sub.30 hydrocarbon radical, saturated or bearing one or more ethylenically unsaturated bonds, and also to a process for preparing it and to compositions for cosmetic use or pharmaceutical use for skin conditions containing this compound.
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: March 30, 1993
    Assignee: L'Oreal
    Inventors: Alexandre Zysman, Guy Vanlerberghe, Henri Sebag
  • Patent number: 5182407
    Abstract: The present invention relates to the compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, denote a methyl or ethyl radical;R.sub.3 denotes a methyl, ethyl or hydroxyethyl radical;A denotes a ##STR2## radical or ##STR3## R denotes H or CH.sub.3 ; X denotes Cl.sup.-, BR.sup.-, I.sup.-, CH.sub.3 OSO.sub.3.sup.-, CH.sub.3 SO.sub.3.sup.-, ##STR4## p and q, which are identical or different, denote integers such that 1.ltoreq.p.ltoreq.15, 0.ltoreq.q.ltoreq.13 and 2.ltoreq.p+q.ltoreq.20;n denotes an integer equal to 2 or 3;m denotes 0 or 1, and m+q.noteq.0;as well as the salts from neutralization by bases, their preparation process and their utilization as an additive in compositions for treatment of keratinous materials.
    Type: Grant
    Filed: July 17, 1991
    Date of Patent: January 26, 1993
    Assignee: L'Oreal
    Inventor: Henri Sebag
  • Patent number: 5164488
    Abstract: The invention relates to compounds of formula: ##STR1## in which m, n, p and q are equal to 0 or 1, p being different from q and the sum m+n+p+q being equal to 2, A denotes a nonionic chain arrangement chosen from the groups:C.sub.2 H.sub.4 O.sub.r and/orC.sub.3 H.sub.5 (OH)O.sub.s,in which r denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 20,s denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 10,u is equal to 0 or 1, with the restriction that when u=0, s and r are also zero,R denotes(i) a linear or branched hydrocarbon radical which has 1 to 32 carbon atoms and can contain one or more oxygen atoms in the chain or bear one or more OH groups or(ii) a (C.sub.8 -C.sub.18 alkyl)phenyl radical.These compounds can be used for preparing stable chemical compounds, for conveying active substances or for forming vesicles.
    Type: Grant
    Filed: February 13, 1991
    Date of Patent: November 17, 1992
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Alexandre Zysman, Henri Sebag
  • Patent number: 5149860
    Abstract: The invention relates to a lipid compound of formula (I): ##STR1## where R.sub.1 denotes a C.sub.11 to C.sub.21 alkyl or alkenyl radical and R.sub.2 denotes a linear or branched C.sub.8 to C.sub.30 hydrocarbon radical, saturated or bearing one or more ethylenically unsaturated bonds, and also to a process for preparing it and to compositions for cosmetic use of pharmaceutical use for skin conditions containing this compound.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: September 22, 1992
    Assignee: L'Oreal
    Inventors: Alexandre Zysman, Guy Vanlerberghe, Henri Sebag
  • Patent number: 5141929
    Abstract: Ethers and/or esters of D-desosamine having the formula ##STR1## whereinn represents 0 or 1; R and R', each independently, represent linear or branched alkyl having 1-30 carbon atoms, alkenyl having 5-21 carbon atoms, cycloalkyl having 4-10 carbon atoms, cycloalkylalkyl having 5-11 carbon atoms or phenyl or arylalkyl optionally substituted; or R can represent hydrogen when n=1 and R' can represent hydrogen when n=0, the number of carbon atoms of R, R' or R+R' being equal to 9 to 33 inclusive; or R represents the aglyconic part of erythralosamine and R' represents linear or branched alkyl having 9-30 carbon atoms or alkenyl having 11-21 carbon atoms; and the .alpha. and .beta. anomers, their mixture and their salts.These compounds are usefully employed as anti-bacteria and anti-fungus agents in pharmaceutical and cosmetic compositions.
    Type: Grant
    Filed: December 6, 1989
    Date of Patent: August 25, 1992
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Michel Phillippe, Henri Sebag
  • Patent number: 5137923
    Abstract: Lipophilic quaternary ammonium salicylate, characterized in that it corresponds to the formula: ##STR1## in which: (i) R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, denote an alkyl or alkylcycloalkyl radical, optionally substituted or interrupted;(ii) R.sub.3 and/or R.sub.4 denote(s) a group:R.sub.8 --OC.sub.2 H.sub.3 R.sub.7 ].sub.n [OCH.sub.2 CHOH--CH.sub.2 ].sub.pin which: 0.ltoreq.n.ltoreq.4 and p denotes 0 or 1; R.sub.8 denotes H or an alkyl, alkenyl, alkylcycloalkyl or alkylaryl radical;(iii) R.sub.4 denotes an alkylphenyl radical;(iv), (v) R.sub.1 and R.sub.2 can form a saturated or unsaturated aromatic or non-aromatic heterocycle;(vi) R.sub.1, R.sub.2 and R.sub.3 form polycyclic derivatives with the nitrogen atoms; R.sub.5 denotes a group corresponding to the formula: ##STR2## in which n is an integer varying between 0 and 10.
    Type: Grant
    Filed: June 21, 1990
    Date of Patent: August 11, 1992
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag, Michel Hocquaux, Bernard Jacquet, Jean P. Laugier
  • Patent number: 5124081
    Abstract: Amphiphilic lipid compound having the formula: ##STR1## in which: R.sub.1 denotes a C.sub.7 -C.sub.21 alkyl or alkenyl radical,R.sub.2 denotes a saturated or unsaturated C.sub.7 -C.sub.31 hydrocarbon radical,COA denotes a group chosen from the following groups:a) COOM, M being H, Na, K, NH.sub.4 or a substituted ammonium ion derived from an amine,b) ##STR2## B being a radical derived from mono- or polyhydroxylated primary or secondary amines and R denoting a hydrogen atom or a methyl, ethyl or hydroxyethyl radical,c) ##STR3## Q denoting a substituted aminoalkyl or ammonioalkyl radical and R having the meaning indicated for b), andd) COOZ, Z representing the residue of a C.sub.3 -C.sub.7 polyol, and a process for its preparation.Cosmetic or dermopharmaceutical composition comprising the said compound and especially an aqueous dispersion of liposomes.
    Type: Grant
    Filed: June 24, 1986
    Date of Patent: June 23, 1992
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Alexandre Zysman, Henri Sebag
  • Patent number: 5112601
    Abstract: The alkyl esters of N-carboalkyloxy-11-aminoundecanoic acids have the following general formula: ##STR1## wherein R is linear or branched C.sub.7-30 alkyl, linear or branched C.sub.4-22 alkenyl or a radical of formula: ##STR2## wherein n is 0 to 5R" is H or linear or branched C.sub.1-9 alkyl, andR' is linear C.sub.10-18 alkyl.These esters, and esters wherein R is additionally hydrogen or C.sub.1-6, have an application as thickening agents in organic media particularly in the cosmetic field.
    Type: Grant
    Filed: May 17, 1990
    Date of Patent: May 12, 1992
    Assignee: L'Oreal
    Inventors: Henri Sebag, Didier Semeria
  • Patent number: 5096713
    Abstract: Retinoic esters of L-cladinose have the formula ##STR1## wherein the ##STR2## radical is (all trans) retinoyl, (13 cis) retinoyl or etretinoyl, and R.sub.2 represents linear or branched alkyl having 1-24 carbon atoms; and the .alpha. and .beta. anomers and their mixtures.These esters are usefully employed in human and veterinary medicines and in cosmetic compositions.
    Type: Grant
    Filed: March 15, 1990
    Date of Patent: March 17, 1992
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5091522
    Abstract: Retinoic esters of D-desosamine have the formula ##STR1## wherein the ##STR2## radical is (all trans) retinoyl, (13 cis) retinoyl or etretinoyl, and R.sub.2 represents linear or branched alkyl having 1-24 carbon atoms; and the .alpha. and .beta. anomers, their mixtures and their salts.These esters are usefully employed in human and veterinary medicines and in cosmetic compositions.
    Type: Grant
    Filed: March 15, 1990
    Date of Patent: February 25, 1992
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5071640
    Abstract: Non-ionic products of the formula:R--X--[C.sub.2 H.sub.3 (OCH.sub.2 CH.sub.2).sub.n(OH)--CH.sub.2 --Y--R'in which R and R' denote alkyl or alkenyl radicals having from 6 to 20 carbon atoms, the sum of the numbers of carbon atoms in R and R' being 24 to 32; X denotes an oxygen atom, a sulphur atom or a sulphoxide group; Y denotes a sulphur atom, a sulphoxide group or a methylene group (if Y denotes methylene, the sum of the numbers of carbon atoms in R and R' is 22 to 30); and n denotes an integer or decimal number from 1 to 40 are disclosed. These non-ionic compounds are suitable for use in pharmaceutical or cosmetic applications, in particular for the care of the skin or hair.
    Type: Grant
    Filed: February 6, 1989
    Date of Patent: December 10, 1991
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 5045533
    Abstract: All trans or 13-cis retinoic acid esters of macrolide and lincosamide antibiotics. These esters are useful in the therapeutic and cosmetic treatment of dermatosis and principally in the treatment of acne.
    Type: Grant
    Filed: August 24, 1988
    Date of Patent: September 3, 1991
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag, Didier Dupuis, Andre Rougier
  • Patent number: 5019567
    Abstract: A pharmaceutical or cosmetic composition for topical application comprises, in a physiologically acceptable support, the combination of benzoyl peroxide and at least one quaternary ammonium lipophilic salicylate having general formula (I): ##STR1## where: (i) R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may be identical or different, representing a substituted or interrupted alkyl or cycloalkyl radical;(ii) R.sub.3 and/or R.sub.4 represent(s) the group:R.sub.8 --OC.sub.2 H.sub.3 R.sub.7 ].sub.n [OCH.sub.2 CHOH--CH.sub.2 ].sub.pwhere O.ltoreq.n.ltoreq.4 and p is 0 or 1; R.sub.8 represents H or an alkyl, alkenyl, alkylcycloalkyl or alkylanyl radical;(iii) R.sub.4 represents an alkylenephenyl radical;(iv), (v): R.sub.1 and R.sub.2 may form an aromatic or nonaromatic saturated or unsaturated heterocycle;(vi) R.sub.1, R.sub.2 and R.sub.3 together with nitrogen, may form polycyclic derivatives; and R.sub.5 represents a group having the formula: ##STR2## where n may vary from 0 to 10.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: May 28, 1991
    Assignee: L'Oreal
    Inventors: Michel Philippe, Michel Hocquaux, Henri Sebag, Irina Beck, Jean P. Laugier
  • Patent number: 5008406
    Abstract: The invention relates to compounds of formula: ##STR1## in which m, n, p and q are equal to 0 or 1, p being different from q and the sum m+n+p+q being equal to 2, A denotes a nonionic chain arrangement chosen from the groups:--C.sub.2 H.sub.4 O--.sub.rand/or--C.sub.3 H.sub.5 (OH)O--.sub.s,in which r denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 20,s denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 10,u is equal to 0 or 1, with the restriction that when u=0, s and r are also zero,R denotes(i) a linear or branched hydrocarbon radical which has 1 to 32 carbon atoms and can contain one or more oxygen atoms in the chain or bear one or more OH groups or(ii) a (C.sub.8 -C.sub.18 alkyl)phenyl radical.These compounds can be used for preparing stable chemical compounds, for conveying active substances or for forming vesicles.
    Type: Grant
    Filed: April 20, 1989
    Date of Patent: April 16, 1991
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Alexandre Zysman, Henri Sebag
  • Patent number: 5004734
    Abstract: Diaromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: Societe Anonyme Dite: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5004733
    Abstract: Esters of the etretinic type or related to macrolides and lincosamides are employed in the treatment of acne and psoriasis.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: Societe Anonyme Dite: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5004730
    Abstract: Polycyclic aromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5004732
    Abstract: Polyaromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: Societe Anonyme Dite: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5004729
    Abstract: Aromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: Societe Anonyme Dite: L'Oreal
    Inventors: Michel Philippe, Henri Sebag
  • Patent number: 5004731
    Abstract: Unsaturated cycloaliphatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 2, 1991
    Assignee: Societe Anonyme Dite: L'Oreal
    Inventors: Michel Philippe, Henri Sebag