Patents by Inventor Henri Sebag

Henri Sebag has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5001156
    Abstract: Lipophilic quaternary ammonium salicylate, characterized in that it corresponds to the formula: ##STR1## in which: (i) R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, denote an alkyl or alkylcycloalkyl radical, optionally substituted or interrupted;(ii) R.sub.3 and/or R.sub.4 denote(s) a group:R.sub.8 [OC.sub.2 H.sub.3 R.sub.7 ].sub.n [OCH.sub.2 CHOH--CH.sub.2 ].sub.pin which 0.ltoreq.n.ltoreq.4 and p denotes 0 or 1; R.sub.8 denotes H or an alkyl, alkenyl, alkylcycloalkyl or alkylaryl radical;(iii) R.sub.4 denotes an alkylphenyl radical;(iv), (v) R.sub.1 and R.sub.2 can form a saturated or unsaturated aromatic or non-aromatic heterocycle;(vi) R.sub.1, R.sub.2 and R.sub.3 form polycyclic derivatives with the nitrogen atoms; R.sub.5 denotes a group corresponding to the formula: ##STR2## in which n is an integer varying between 0 and 10.
    Type: Grant
    Filed: December 1, 1987
    Date of Patent: March 19, 1991
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag, Michel Hocquaux, Bernard Jacquet, Jean P. Laugier
  • Patent number: 4971789
    Abstract: Mixture of ionic polyethers of formula: ##STR1## where R denotes C.sub.1 -C.sub.20 alkyl or alkenyl or C.sub.6 14 C.sub.20 aryl or aralkyl;z=1 or 2; y=3-20; T=0 or S; u=0 or 1; m=3-11;n=0-11;n.noteq.0 when u=1 and m+n.gtoreq.4; B=OH or A; A is an ionic group --COOM; --(CH.sub.2).sub.u --S--(W)COOH (with W=--CH.sub.2 --, --CH.sub.2 --CH.sub.2 -- or --CH(CH.sub.3)-- and u'=u); --CH.sub.2 --O--S).sub.3 M, (M being an alkali metal or an ammonium ion optionally substituted by methyl, ethyl, hydroxyethyl, hydroxypropyol, methylhydroxypropyl or methyldihydroxypropyl); ##STR2## (where R.sub.1, R.sub.2 and R.sub.3 denotes methyl, ethyl, hydroxyethyl or dihydroxypropyl, R.sub.1 and R.sub.2 being capable of forming with N an amino or ammonio heterocyclic ring, HV is an inorganic or organic acid and Q- is an anion); ##STR3## HV (with R.sub.4 =methyl or ethyl and x=2 or 3) ##STR4## with the provision that when T=0 and u=0, A denotes only (b); and process for preparing them.
    Type: Grant
    Filed: December 5, 1984
    Date of Patent: November 20, 1990
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 4963535
    Abstract: Cosmetic compositions for cleaning hair, the skin or for removing make-up from the face or from the eyes, containing (a) a foaming surface-active agent, (b) an aqueous, hydroalcoholic or oily carrier and (c) a nonfoaming, nonionic product, poorly soluble in water, of general formula (I):R--O--[C.sub.2 H.sub.3 --CH.sub.2 R.sub.1 --O].sub.p [C.sub.2 H.sub.3 O--CH.sub.2 OH].sub.n H (I)in which R denotes a C.sub.8 -C.sub.20 alkyl radical, R.sub.1 denotes a C.sub.7 -C.sub.17 alkyl radical or an alkoxy radical containing from 8 to 20 carbon atoms, R+R.sub.1 containing from 21 to 31 carbon atoms and preferably from 23 to 27, p denotes the exact value of 1 or a statistical mean value of between 1 and 2, and n denotes a statistical mean value of between 2 and 10 and preferably between 2.5 and 7.The presence of the component (c) improves the compatibility of the foaming surface-active agents (a) with the skin and the mucosa.
    Type: Grant
    Filed: February 2, 1988
    Date of Patent: October 16, 1990
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4960772
    Abstract: A pharmaceutical and cosmetic composition for topical application comprises in a physiologically acceptable medium a combination of benzoyl peroxide and a quaternary ammonium salt selected from a quaternary ammonium alkyl sulfate of sulfonate, an aryl sulfonate and an alkyl aryl sulfonate.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: October 2, 1990
    Assignee: L'Oreal
    Inventors: Henri Sebag, Irina Beck
  • Patent number: 4946670
    Abstract: Mixture of compounds of general formula: ##STR1## in which R denotes a saturated C.sub.10 -C.sub.12 hydrocarbon radical, or mixture of such radicals, and n has a mean statistical value from 2 to 15, and preferably from 3 to 12.These products are very well tolerated by the skin and the mucosa, and are advantageously used in cosmetic or pharmaceutical compositions.
    Type: Grant
    Filed: August 2, 1988
    Date of Patent: August 7, 1990
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4940573
    Abstract: Cationic surface-active products of the formula: ##STR1## in which R.sub.1 =C.sub.4 -C.sub.20 aliphatic radical, R.sub.2 =C.sub.4 -C.sub.20 alkyl, alkoxymethyl or alkenyloxy radical, p=1-2.5, n=2-20 and G denotes an amine or amine oxide group, and their salts are disclosed for use principally in cosmetics.
    Type: Grant
    Filed: December 9, 1988
    Date of Patent: July 10, 1990
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4940575
    Abstract: 4-Hydroxyisoxazole derivatives corresponding to the formula: ##STR1## wherein: R represents a linear or branched alkyl or hydroxyalkyl radical with 1 to 23 carbon atoms, a linear or branched alkenyl radical with 2 to 23 carbon atoms, a phenyl radical, or a benzyl radical, andR.sub.1 represents OR.sub.2, --NHR.sub.3, or --NH--NHR.sub.4,R.sub.2 represents a hydrogen atom or an alkyl radical with 1 to 24 carbon atoms,R.sub.3 represents a hydrogen atom, an alkyl radical with 1 to 20 carbon atoms, or a ##STR2## radical, where n is 2 to 3 and r' and r" are identical or different, representing a hydrogen atom or a lower alkyl radical or forming a heterocycle when taken together such as morpholine, piperidine, or piperazine,R.sub.4 represents a hydrogen atom or a benzyl radical,and the salts of the formula (I) compounds.These derivatives are applicable to therapeutic and cosmetic fields, in particular to counteract the harmful effects of the sun.
    Type: Grant
    Filed: June 26, 1989
    Date of Patent: July 10, 1990
    Assignee: Societe Anonyme dite:L'Oreal
    Inventors: Alexandre Zysman, Henri Sebag
  • Patent number: 4885402
    Abstract: Process for preparing polyglycerolated nonionic surfactants from (poly)hydroxylated organic compounds, by condensing glycerol monochlorohydrin with the said (poly)hydroxylated compound in the presence of a strong base, at a temperature below 150.degree. C. and in the presence of an aromatic solvent, removing the water formed by distillation as it forms.This process makes it possible to condense a relatively large quantity of glycerol monochlorohydrin in a single step, while limiting the formation of polyglycerols, and to obtain a good quality surfactant which is usable in cosmetic compositions.
    Type: Grant
    Filed: June 3, 1988
    Date of Patent: December 5, 1989
    Assignee: L'Oreal
    Inventor: Henri Sebag
  • Patent number: 4880620
    Abstract: Perfluorinated surface-active block or random oligomers of the formula ##STR1## where R denotes a C.sub.2 -C.sub.18 -hydrocarbon or-hydroflurocarbon radical,Y denotes a C.sub.6 -C.sub.13 -fluorocarbon or-hydrofluorocarbon radical which can contain a chain oxygen atom,Z denotes a group which confers solubility in water andp and q denote integers or decimal numbers from 0.5 to 30 are provided. They are suitable for use in cosmetic compositions for the treatment of hair. They slow down the flow of sebum and the rate at which hair becomes greasy again.
    Type: Grant
    Filed: August 2, 1988
    Date of Patent: November 14, 1989
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 4879107
    Abstract: Foaming cosmetic compositions for cleansing the hair or the skin, containing, in proportions from 0.5 to 95%, a surfactant oligomer of formula (I): ##STR1## in which: R denotes a C.sub.10 -C.sub.18 hydrocarbon radical;R.sub.1 and R.sub.2, which may be identical or different, denote H or CH.sub.3 ;n denotes an average statistical value from 10 to 35;m denotes zero or an average statistical value .ltoreq.5;m/n preferably being .ltoreq.0.25M denotes H, Na, K or an ammonium group.These compositions are characterized by good foaming power, good compatibility with the skin and the ocular mucosae and a suitable detergent power.
    Type: Grant
    Filed: May 4, 1988
    Date of Patent: November 7, 1989
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag, Michele Lagoutte, Jean F. Grollier
  • Patent number: 4857525
    Abstract: Quaternary ammonium retinoate, characterized in that it corresponds to the formula: ##STR1## in which: X-- denotes either an all-trans-retinoate of formula (I): ##STR2## or a 13-cis= retinoate of formula: ##STR3## (i) R.sub.1, R.sub.2 and R.sub.3, which may be identical or different, denote a saturated C.sub.1 -C.sub.4 linear alkyl group capable of bearing one or more hydroxyl group(s) at the end of the chain or in the chain;R.sub.4 denotes a C.sub.12 -C.sub.18 linear alkenyl or alkyl group;(ii) R.sub.3 denotes a group: ##STR4## in which n equals 0 or 1, R.sub.5 denotes a hydrogen atom, a hydroxyl, a halogen atom, a C.sub.1 -C.sub.18 -hydroxyl alkyl or alkyl group or a C.sub.2 to C.sub.18 acyl group;R.sub.1, R.sub.2 and R.sub.4 having the same meanings as those under (i);(iii) R.sub.1 and R.sub.2 can form an aliphatic heterocycle optionally containing an oxygen atom, another nitrogen atom or a sulphur atom;R.sub.3 and R.sub.4 having the same meanings as those under (i) and (ii).
    Type: Grant
    Filed: May 5, 1988
    Date of Patent: August 15, 1989
    Assignee: L'Oreal
    Inventors: Michel Philippe, Henri Sebag, Didier S. Leger, Jean L. Leveque
  • Patent number: 4827003
    Abstract: The invention relates to compounds of formula: ##STR1## in which m, n, p and q are equal to 0 or 1, p being different from q and the sum m+n+p+q being equal to 2, A denotes a nonionic chain arrangement chosen from the groups:--C.sub.2 H.sub.4 O--.sub.rand/or--C.sub.3 H.sub.5 (OH)O--.sub.s,in whichr denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 20,s denotes a number which can assume all integral values between 0 and 5 or a statistical average value between 0 and 10,u is equal to 0 to 1, with the restriction that when u=0, s and r are also zero,R denotes(i) a linear or branched hydrocarbon radical which has 1 to 32 carbon atoms and can contain one or more oxygen atoms in the chain or bear one or more OH groups or(ii) a (C.sub.8 -C.sub.18 alkyl)phenyl radical.These compounds can be used for preparing stable chemical compounds, for conveying active substances or for forming vesicles.
    Type: Grant
    Filed: June 13, 1986
    Date of Patent: May 2, 1989
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Alexandre Zysman, Henri Sebag
  • Patent number: 4820820
    Abstract: Cationic surface-active products of the formula:R.sub.1 --O[C.sub.2 H.sub.3 (R.sub.2)O--].sub.p [C.sub.2 H.sub.3 (CH.sub.2 OH)O].sub.(n-1) CH.sub.2 --CHOH--CH.sub.2 --Gin which R.sub.1 =C.sub.4 -C.sub.20 aliphatic radical, R.sub.2 =C.sub.4 -C.sub.20 alkyl, alkoxymethyl or alkenyloxy radical, p=1-2.5, n=2-20 and G denotes an amine or amine oxide group, and their salts are disclosed for use principally in cosmetics.
    Type: Grant
    Filed: September 23, 1987
    Date of Patent: April 11, 1989
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4814166
    Abstract: Anionic oligomers of the general formula: ##STR1## in which T denotes the radical ##STR2## optionally in a mixture with the OH radical; u=0 or 1; p=1 or 2; M=H, Na, K, ammonium or a mono-, di- or tri-(alkyl or hydroxyalkyl)ammonium group, the alkyl part containing 1 to 4 carbon atoms; n=5-30; z=1-6; and R denotes an aliphatic, alicyclic, aryl, alkylaryl or aralkyl radical of valency z, which can contain 1 or more oxygen atoms, it being possible for the formula (I) to contain minor proportions of intermolecular or intra-molecular branches originating from a bis-epoxide.These oligomers are prepared by the addition of n mols of epihalogenohydrin, and optionally of a minor proportions of bis-epoxide, to 1 mol of compoundsR(OH).sub.z (II),in the presence of a Lewis acid, the polyhalogen compounds obtained then being converted into polythiocarboxylic compounds by reaction with a salt or an ester of thiloactic acid, thioglycolic acid or .alpha.-mercaptopropionic or .beta.
    Type: Grant
    Filed: May 20, 1986
    Date of Patent: March 21, 1989
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 4788345
    Abstract: Mixture of compounds of general formula: ##STR1## in which R denotes a saturated C.sub.10 -C.sub.12 hydrocarbon radical, or mixture of such radicals, and n has a mean statistical value from 2 to 15, and preferably from 3 to 12.These products are very well tolerated by the skin and the mucosa, and are advantageously used in cosmetic or pharmaceutical compositions.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: November 29, 1988
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4787911
    Abstract: The invention provides surface-active random oligomers of the general formula:R.sub.1 --O--C.sub.2 H.sub.3 (Z)--O].sub.n H (I)in which R.sub.1 denotes a linear or branched, saturated or unsaturated aliphatic hydrocarbon radical or a cyclo-aliphatic, aromatic or alkylaromatic radical containing 1 to 30 carbon atoms, Z denotes a group A and/or at least one group corresponding to the formula (II)R.sub.2 --O--C.sub.2 H.sub.3 (A)--O].sub.m CH.sub.2 -- (II)in which R.sub.2 denotes a hydrocarbon radical having the meaning indicated for R.sub.1 and containing a number of carbon atoms from 8 to 30, n denotes an average statistical value from 1 to 20, m denotes an average statistical value from 0.5 to 10 and A denotes a group of hydrophilic character. These oligomers can be used in cosmetic or pharmaceutical compositions.
    Type: Grant
    Filed: December 17, 1986
    Date of Patent: November 29, 1988
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4778675
    Abstract: Perfluorinated surface-active block or random oligomers of the formula ##STR1## where R denotes a C.sub.2 -C.sub.18 -hydrocarbon or-hydrofluorocarbon radical,Y denotes a C.sub.6 -C.sub.13 -fluorocarbon or-hydrofluorocarbon radical which can contain a chain oxygen atom,Z denotes a group which confers solubility in water and p and q denote integers or decimal numbers from 0.5 to 30 are provided.They are suitable for use in cosmetic compositions for the treatment of hair. They slow down the flow of sebum and the rate at which hair becomes greasy again.
    Type: Grant
    Filed: February 25, 1986
    Date of Patent: October 18, 1988
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 4678665
    Abstract: Products of formula (I) ##STR1## in which R=C.sub.6-18 aromatic or alkylaromatic of valency z, R'=H, C.sub.1-16 alkyl or phenyl, A=CH.sub.2 or CH.sub.2 --O-- and, in the latter case, R'.noteq.H, x=1-8, y=1-20, z=1-3 and T denotes one or more anionic groups or a mixture of anionic groups and non-ionic groups are disclosed.These compounds are prepared by the reaction of a phenol R(OH).sub.z with an epoxide ##STR2## and an epihalogenohydrin ##STR3## in which X=Cl or Br, this being followed by replacement of X with one or more hydrophilic groupsThese compounds can be used as surface-active agents.
    Type: Grant
    Filed: August 2, 1984
    Date of Patent: July 7, 1987
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag
  • Patent number: 4677232
    Abstract: Process for the preparation of water-soluble or water-dispersible polyglycerolated nonionic surface-active agents.This process is characterized by the polyaddition of glycerol chlorohydrin and of a strong base, and preferably sodium or potassium hydroxide in an aqueous solution, to a (poly)hydroxylated compound.This process has the advantage of replacing glycidol, which is usually employed, by glycerol chlorohydrin, which is less costly, easier to store than glycidol, and also of avoiding the flash distillation of a flammable volatile solvent.
    Type: Grant
    Filed: December 13, 1985
    Date of Patent: June 30, 1987
    Assignee: L'Oreal
    Inventors: Henri Sebag, Guy Vanlerberghe
  • Patent number: 4668509
    Abstract: Polythioalkanecarboxylic products of formula: ##STR1## in which R.sub.1 =C.sub.6-30 aromatic or alkylaromatic radical; R.sub.2 =C.sub.4 -C.sub.18 alkyl; A=C.sub.1-3 alkylene; M=H, alkali metal or alkaline earth metal, an ammonium ion or a substituted ammonium ion; z=1-6; m=1-10; n=1-20; and u=zero or 1 are disclosed.A process of preparation comprising, in a first stage, reacting an alcohol or phenol of formula R.sub.1 (OH) .sub.z (II) with an epihalogenohydrin of formula ##STR2## in which X=Cl or Br, in the presence of a Lewis acid, to give the intermediates of the formula: ##STR3## and in a second stage, the two compounds of formulae R.sub.2 SH (V) and HS--A--COOH (VI), in which R.sub.2 and A have the meanings indicated above, are reacted simultaneously or successively with the compound of the formula (IV) is also disclosed.The compounds of the formula (I) are used in cosmetic compositions.
    Type: Grant
    Filed: August 2, 1984
    Date of Patent: May 26, 1987
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Henri Sebag