Abstract: Disclosed are techniques for implementing group legal placement on rows and grids for an electronic design. These techniques identify a group comprising a plurality of instances. A proxy is identified from the plurality of instances. The group is placed in a row region based in part or in whole upon a plurality of permissible characteristics for the proxy without considering permissible characteristics of one or more remaining instances in the group. A group legality may be performed to determine whether the group is placed in the row region in a group legal manner.

Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Abstract: Disclosed are techniques for implementing routing aware placement for an electronic design. These techniques identify a block having one or more first pins or interconnects to be inserted into a first layer corresponding to a first set of tracks and identify a second set of tracks on a second layer adjacent to the first layer. One or more candidate locations may be generated on the first layer for the block based in part or in whole upon the first set of tracks. The block may be inserted into a candidate location on the first layer based in part or in whole upon respective costs or routability of the one or more candidate locations with respect to the second set of tracks.

Abstract: The present invention comprises a precision cooking oven that utilizes laser sheets to cook food, thus creating homogeneously heated and uniformly seared food bodies and surfaces. Laser sheets move back and forth evenly injecting heat into items being cooked. All food cold or hot areas can be eliminated since intersecting laser lines can be completely projected on and accommodate an item's exterior surfaces. Items with non-uniform cross-sections and properties can be cooked uniformly by controlling the exact amount of energy projected into differing sections of the food. The oven is also capable of cooking autonomously. Since laser sheets can be precisely controlled, cooking results can be very predictable once the boundary conditions for a thermal analysis are determined. The oven can detect the properties of the items to be cooked and thereafter compute the needed time and power to achieve the desired results stipulated by an oven operator.

Abstract: Disclosed are techniques for implementing legal placement with contextual awareness for an electronic design. These techniques identify one or more hierarchies from one or more groups or one or more instances located at these one or more hierarchies in a layout or floorplan. A plurality of instances including the one or more identified instances may be promoted to an honorary top hierarchy. A layout operation may then be performed on the one or more identified instances based in part or in whole upon a boundary requirement and context information.

Abstract: A service description may be used in network virtualization in order to specify requirements of an application. In order to provide network virtualization for generic networking components, including legacy networking components, the service description is mapped to a logical network implementation and then subsequently mapped to a physical implementation.

Abstract: Compounds of formula (I) wherein X1, X2, W, R1 to R5, L and m have the meaning according to the claims, are glucosidase inhibitors, and can be employed, inter alia, for the treatment of Alzheimer's disease.

Abstract: The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).

Abstract: Disclosed are pyrazole compounds, and pharmaceutically acceptable compositions thereof. The compounds and the compositions can be used for positive allosteric modulators of follicle stimulating hormone receptor (FSHR).

Abstract: Novel benzamide derivatives of formula (I) wherein W1, W2, R1 to R10 and X have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.

Abstract: The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).

Abstract: The present invention relates to imidazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).

Abstract: The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).

Abstract: Novel benzamide derivatives of formula (I) wherein W1, W2, R1 to R7, R6, X and Y have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.

Abstract: Compounds of formula (I) wherein X1, X2, W, R1 to R5, L and m have the meaning according to the claims, are glucosidase inhibitors, and can be employed, inter alia, for the treatment of Alzheimer's disease.

Abstract: Compounds of formula (I) wherein X1, X2, W, R1 to R5, L and m have the meaning according to the claims, are glucosidase inhibitors, and can be employed, inter alia, for the treatment of Alzheimer's disease.

Abstract: Novel dihydropyrazole derivatives of formula (I) wherein L, R, R3, R4, R5, R6, R7, X1, X2, X3, X4, Y, m and n have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.

Abstract: Aspects of the present disclosure involve systems, methods, computer program products, and the like, for utilizing an access log of a proxy server device of a content delivery network (CDN) to detect and mitigate a denial of service (DOS) on a web or content server hosted by the CDN. Through an analysis of the content requests received at the proxy server listed in the access logs, one or more IP addresses may be identified as involved in a potential DOS attack or other suspicious behavior. Once identified, the suspicious activities of the one or more IP addresses may be tracked and aggregated over a particular period of time, with each detected suspicious request to the content server being counted. The count of suspicious requests to the content server may then be compared to one or more threshold values and a remediation action may occur when the thresholds are met or exceeded.

Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.

Abstract: Novel dihydropyrazole derivatives of formula (I) wherein L, R, R3, R4, R5, R6, R7, X1, X2, X3, X4, Y, m and n have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.