Patent number: RE28972
Abstract: 5-Aryl-1H-1,5-benzodiazepine-2,4-diones of a formula selected from the group consisting of ##SPC1##Wherein ##SPC2##-- A -- Xwherein R.sub.1 is allyl, methylallyl, dimethylallyl, chloroallyl, cyclohexyl, cycloalkylmethyl, cycloalkenylmethyl of 4 to 7 carbon atoms, phenyl, tolyl, xylyl, methoxyphenyl, dimethoxyphenyl, halophenyl, phenylalkyl of 7 to 8 carbon atoms, pyridyl or--A --Xwhere A is straight or branched alkylene of 1 to 4 carbon atoms, andX is hydroxyl, alkoxy, acyloxy, dialkylamino of 2 to 4 carbon atoms, or a 5- to 6-membered nitrogen-containing heterocyclic ring linked to A through a ring nitrogen atom,R.sub.2 is hydrogen or methyl,R.sub.3 is naphthyl, pyrimidyl, thienyl, pyridyl, methylpyridyl or halopyridyl,R.sub.4 is hydrogen, methyl, methoxy, trifluoromethyl, cyano, halogen, lower alkanoyl or (lower alkoxy of 1 to 2 carbon atoms)-carbonyl,R.sub.5 is hydrogen, methyl, ethyl, methoxy, trifluoromethyl, cyano, nitro, halogen, lower alkanoyl or lower alkoxy-carbonyl,R.sub.
Type:
Grant
Filed:
December 4, 1975
Date of Patent:
September 21, 1976
Assignee:
Boehringer Ingelheim GmbH
Inventors:
Karl-Heinz Weber, Herbert Merz, Karl Zeile, Rolf Giesemann, Peter Danneberg