Patents by Inventor Herbert Merz

Herbert Merz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-[(Methoxymethyl-furyl)-methyl]-morphinans or -6,7-benzomorphans and salts thereof
    Patent number: 3981874
    Abstract: Compound of the formula ##SPC1##WhereinR.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 3 carbon atoms,R.sub.3 is hydrogen or methyl,R.sub.4 is ##SPC2##R.sub.5 is hydrogen, methyl or acetyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics.
    Type: Grant
    Filed: October 15, 1974
    Date of Patent: September 21, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Merz, Adolf Langbein, Gerhard Walther, Klaus Stockhaus
  • Pharmaceutical compositions containing an N-(furyl- or thienyl-methyl)-desoxy-normorphine or norcodeine and method of use
    Patent number: 3975368
    Abstract: Pharmaceutical compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR is hydrogen, methyl or acetyl,R' is hydrogen or methyl, andX is oxygen or sulfur,Or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as opiate antagonists, analgesics and antitussives.
    Type: Grant
    Filed: October 8, 1975
    Date of Patent: August 17, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerhard Walther, Herbert Merz, Adolf Langbein, Klaus Stockhaus
  • N-(1-(.omega.-phenyl-alkyl)-piperidyl-4)-N-(.alpha.-pyridyl)-carboxylic acid amides and salts thereof
    Patent number: 3933832
    Abstract: Compounds of the formula ##SPC1##WhereinR is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, andn is an integer from 2 to 4, inclusive,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as non-narcotic analgesics.
    Type: Grant
    Filed: August 14, 1974
    Date of Patent: January 20, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus
  • Pharmaceutical compositions containing a carboxylic acyl derivative of digoxin and method of use
    Patent number: 3932626
    Abstract: Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula ##SPC1##Wherein R.sub.1 is alkyl of 2 to 12 carbon atoms, halo-(alkyl of 1 to 4 carbon atoms), aryl-(alkyl of 1 to 4 carbon atoms), cycloalkyl-(alkyl of 1 to 4 carbon atoms) or cycloalkyl of 3 to 8 carbon atoms; and a method of using the same as cardiotonics.
    Type: Grant
    Filed: January 16, 1974
    Date of Patent: January 13, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Walter Losel, Herbert Merz, Wolfgang Hoefke, Werner Traunecker
  • 2-Heteroaryl-methyl)-5,9.beta.-dialkyl-6,7-benzomorphans and salts thereof
    Patent number: 3931194
    Abstract: Compounds of the formula ##SPC1##Wherein R is hydrogen, methyl or acetyl,R.sub.1 and R.sub.2, which may be identical to or different from each other, are each alkyl of 1 to 3 carbon atoms,R.sub.3 is hydrogen or methyl, andY is oxygen or sulfur,And non-toxic, pharmacologically acceptable acid addition salts thereof; these compounds as well as the salts are useful as analgesics and antitussives, and opiate antagonists.
    Type: Grant
    Filed: June 5, 1973
    Date of Patent: January 6, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Merz, Adolf Langbein, Klaus Stockhaus, Helmut Wick
  • N-(heteroaryl-methyl)-7.alpha.-acyl-6,14-(endoetheno or endoethano)-tetrahydro-nororipavines or-thebaines and salts thereof
    Patent number: 3931187
    Abstract: Compounds of the formula ##SPC1##WhereinR is hydrogen, methyl or acetyl,R.sub.1 is methyl, phenyl, or hydrogen,Z is --CH=CH-- or --CH.sub.2 --CH.sub.2 --,Y is oxygen or sulfur, andR.sub.3 is hydrogen or methyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics and antitussives.
    Type: Grant
    Filed: June 13, 1973
    Date of Patent: January 6, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Klaus Stockhaus
  • N-(heteroaryl-methyl)-6,14-(endoethano or endoetheno)-7.alpha.-hydroxyalkyl-tetrahydro-nororipavines or-northebaines and salts thereof
    Patent number: 3931189
    Abstract: Compounds of the formula ##SPC1##WhereinR.sub.1 is hydrogen, methyl or acetyl,R.sub.2 is hydrogen or methyl,R.sub.3 is hydrogen, methyl, n-propyl, phenethyl or phenyl,R.sub.4 is hydrogen or methyl,Z is --CH=CH-- or --CH.sub.2 --CH.sub.2 --, andY is oxygen or sulfur,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics and antitussives.
    Type: Grant
    Filed: June 13, 1973
    Date of Patent: January 6, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Adolf Langbein, Herbert Merz, Gerhard Walther, Kalus Stockhaus