Patents by Inventor Herwig Buchholz

Herwig Buchholz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080182879
    Abstract: Novel compounds of the formula I in which R, X and n are as defined herein, are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Application
    Filed: April 1, 2008
    Publication date: July 31, 2008
    Inventors: Teresa MUJICA-FERNAUD, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Publication number: 20080171004
    Abstract: The present invention relates to the use of compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, for the development of UV-A or UV-B protection during use, to corresponding novel compounds and compositions, and to corresponding processes for the preparation of compounds and compositions.
    Type: Application
    Filed: March 21, 2006
    Publication date: July 17, 2008
    Inventors: Thomas Rudolph, Herwig Buchholz
  • Publication number: 20080152603
    Abstract: The present invention relates to the use of compounds of the formula (I), with radicals defined in the description, as antioxidants, to corresponding novel compounds and compositions, and to corresponding processes for the preparation of compounds and compositions.
    Type: Application
    Filed: March 21, 2006
    Publication date: June 26, 2008
    Inventors: Thomas Rudolph, Herwig Buchholz
  • Publication number: 20080146589
    Abstract: Novel compounds of the formula I in which R1, R2, R3 and Het are as defined herein, which are inhibitors of tyrosine kinases and/or Raf kinases and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Application
    Filed: January 23, 2008
    Publication date: June 19, 2008
    Inventors: Teresa MUJICA-FERNAUD, Herwig Buchholz, Wilfried Rautenberg, Christian Sirrenberg
  • Patent number: 7378421
    Abstract: Novel compounds of the formula I in which R1, R2, R3 and Het are as defined herein, which are inhibitors of tyrosine kinases and/or Raf kinases and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: May 27, 2008
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Wilfried Rautenberg, Christian Sirrenberg
  • Publication number: 20080112905
    Abstract: The invention relates to complexes of certain flavonoid derivatives, of the formula (1), where R1 and R2 are selected from H and OR11, where OR11 stands, independently of one another, for OH, straight-chain or branched C1- to C20-alkoxy groups, straight-chain or branched C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may in each case also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, with the proviso that at least one radical from R1 and R2 stands for OR11, and R3 to R10 may be identical or different and stand, independently of one another, for radicals which are substantially inert with respect to the UV properties, to compositions which comprise such complexes, to corres
    Type: Application
    Filed: November 3, 2005
    Publication date: May 15, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Christophe Carola, Anne Toullec, Herwig Buchholz
  • Patent number: 7354945
    Abstract: Novel compounds of the formula I in which R, X and n are as defined herein, are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: April 8, 2008
    Assignee: Merck Patent GmbH
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Patent number: 7345090
    Abstract: The invention relates to compounds of the formula I where R1, R2, R3, R4 and R5 have the meanings given in claim 1. The compound is suitable in particular for use in skin care compositions. They protect, firstly, against harmful oxidation reactions and, secondly, also act as UV filters.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: March 18, 2008
    Assignee: Merck Patent Gesellschaft mit Beschraenkter Haftung
    Inventors: Frank Pfluecker, Joachim Buenger, Hans-Juergen Driller, Herwig Buchholz, Ralf Rosskopf
  • Publication number: 20080045478
    Abstract: The invention relates to complexes of specific flavonoid derivatives, to preparations containing derivatives of this type, to corresponding methods for producing said derivatives or preparations containing the latter and to the use of the latter, in particular for the care, preservation or improvement of the general condition of the skin or hair.
    Type: Application
    Filed: July 12, 2005
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Herwig Buchholz, Ralf Rosskopf, Christophe Carola
  • Publication number: 20080044364
    Abstract: The invention relates to compounds of the formula I where R1 to R10 may be identical or different and are selected from H, OR11, straight-chain or branched C1- to C20-alkyl groups or hydroxyalkyl groups, straight-chain or branched C3- to C20-alkenyl groups and/or C3- to C12-cycloalkenyl groups, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, where all OR11, independently of one another, stand for OH, C1- to C20-alkoxy groups, C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, CD stands for a cyclodextrin molecule, o stands for the number 1 and p stands for a number from the range 0.5 to 50, with the proviso that at least 2 radicals from R1 to R7 stand for OH and that at least 1 pair of adjacent —OH groups is present in the molecule.
    Type: Application
    Filed: November 4, 2005
    Publication date: February 21, 2008
    Inventors: Christophe Carola, Anne Toullec, Herwig Buchholz
  • Publication number: 20080044502
    Abstract: The present invention relates to a composition comprising an aqueous or hydroalcoholic extract of bauhinia and to the use of an aqueous or hydroalcoholic extract of bauhinia for the preparation of a composition for the care, preservation or improvement of the general state of the skin or hair, for the prophylaxis or prevention of human skin or human hair ageing processes and for the prophylaxis and/or treatment of diseases associated with skin ageing.
    Type: Application
    Filed: July 18, 2007
    Publication date: February 21, 2008
    Inventors: Corinna WIRTH, Herwig Buchholz
  • Publication number: 20080038213
    Abstract: The invention relates to compounds of the formula (I) or (II), to compositions which comprise such compounds, to corresponding processes for the preparation of the compounds or the compositions comprising same, and to the use thereof as light-protection filters.
    Type: Application
    Filed: July 27, 2005
    Publication date: February 14, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Christophe Carola, Frank Pfluecker, Herwig Buchholz, Hansjurgen Driller, Hans Neunhoeffer, Evgeniy Blyumin
  • Publication number: 20080027133
    Abstract: The invention relates to the use of chromen-4-one derivatives of the formula I where R1 and R2 may be identical or different and are selected from H, —C(?O)—R7, —C(?O)—OR7, alkyl groups, alkenyl groups, hydroxyalkyl groups and/or cycloalkyl groups and/or cycloalkenyl groups, R3 is H or alkyl groups, R4 is H or OR8, R5 and R6 are selected from —H, —OH, alkyl groups, alkenyl groups and hydroxyalkyl groups, and R7 is H, alkyl groups, a polyhydroxyl compound, such as, preferably, an ascorbic acid radical or glycosidic radicals, and R8 is H or alkyl groups, where at least two of the substituents R1, R2 and R4-R6 are different from H or at least one substituent from R1 and R2 is —C(?O)—R7 or —C(?O)—OR7, for the care, preservation or improvement of the general state of the skin or hair.
    Type: Application
    Filed: October 9, 2007
    Publication date: January 31, 2008
    Inventors: Christophe Carola, Herwig Buchholz, Sylvia Huber, Ralf Rosskopf
  • Patent number: 7307100
    Abstract: Novel compounds of the formula I in which R, X, n and m are as defined herein are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: December 11, 2007
    Assignee: Merck Patent GmbH
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Publication number: 20070275244
    Abstract: Disclosed are particles containing substrates and an anion-binding layer, containing one or more anion-forming organic active compounds or active compound/colorant mixtures; processes for preparing said particles and to methods of use thereof in cosmetics, pharmaceuticals, formulations, paints, coatings, plastics, films, in security printing, in security features in documents or identity papers, for coloring seed, for coloring foods or in medicament coatings and for the preparation of pigment compositions and dry preparations.
    Type: Application
    Filed: May 24, 2007
    Publication date: November 29, 2007
    Inventors: Carsten Handrosch, Thomas Rudolph, Herwig Buchholz, Soheila Anzali
  • Publication number: 20070191305
    Abstract: The invention relates to complexes of certain chromone derivatives, to compositions which comprise such derivatives, to corresponding processes for the preparation of the chromone derivatives or of compositions comprising same, and to the use thereof, in particular for the care, maintenance or improvement of the general state of the skin or hair.
    Type: Application
    Filed: March 7, 2005
    Publication date: August 16, 2007
    Inventors: Christophe Carola, Ralf Rosskopf, Herwig Buchholz
  • Publication number: 20070155695
    Abstract: The invention relates to complexes of certain flavonoid derivatives, of the formula I compositions which comprise such derivatives, corresponding processes for the preparation of the flavonoid derivatives or of compositions comprising same, and the use thereof, in particular for the care, preservation or improvement of the general state of the skin or hair. Formula (1), in which Z1 to Z4 and Z6 to Z10 each, independently of one another, denote H, OH, CH3COO, alkoxy, hydroxyalkoxy, mono- or oligoglycoside radicals and where the alkoxy and hydroxyalkoxy groups may be branched and unbranched and can have 1 to 18 C atoms. Formula (II) denotes, Z5 is a mono- or the oligoglycoside radical, where bonded to this glycoside radical, in each case via an —O— group, is at least one radical selected from certain benzo molecule.
    Type: Application
    Filed: December 27, 2004
    Publication date: July 5, 2007
    Inventors: Corinna Wirth, Ralf Rosskopf, Herwig Buchholz
  • Publication number: 20070134172
    Abstract: The invention relates to a novel flavonoid derivative, to an extract comprising the flavonoid derivative, to the cosmetic and pharmaceutical use thereof, to preparations comprising the flavonoid derivative or extract, and to a process for the preparation of the flavonoid derivative or extract.
    Type: Application
    Filed: November 5, 2004
    Publication date: June 14, 2007
    Inventors: Herwig Buchholz, Corinna Wirth, Christophe Carola, Rosane Alves Fontes
  • Publication number: 20070079754
    Abstract: The present invention relates to the use of self-tanning substances for application to the human skin, with application taking place at elevated temperature, to corresponding methods of application to the human skin and to a cosmetic formulation which is suitable for said purpose.
    Type: Application
    Filed: November 17, 2004
    Publication date: April 12, 2007
    Inventors: Sabine Hitzel, Hansjurgen Driller, Herwig Buchholz, Silke Hornung, Francois Marchio, Frank Pflucker, Ralf Rosskopf
  • Publication number: 20060292093
    Abstract: The invention relates to compounds that are selected from the compounds of formulas (Ia)-(Ic) and to their production and use in cosmetic and dermatological products.
    Type: Application
    Filed: July 19, 2004
    Publication date: December 28, 2006
    Inventors: Christophe Carola, Herwig Buchholz