Patents by Inventor Herwig Buchholz

Herwig Buchholz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060246149
    Abstract: The present invention relates to antimicrobial pigments, obtainable by agitating a suspension comprising one or more inorganic pigments and an antimicrobial compound, especially silver oxide, and their use in various applications, such as cosmetics, inks, lacquers or plastics.
    Type: Application
    Filed: March 24, 2004
    Publication date: November 2, 2006
    Inventors: Herwig Buchholz, Valerie Bicard-Benhamou, Markus Brunner, Jerzy Meduski
  • Patent number: 7128900
    Abstract: The invention relates to a preparation having light-protection properties comprising at least one compound of the formula I where R1 and R2 are selected from H and OR11, where each OR11, independently of the others, is OH, a straight-chain or branched C1- to C20-alkoxy group, a straight-chain or branched C3- to C20-alkenyloxy group, a straight-chain or branched C1- to C20-hydroxyalkoxy group, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or a C3- to C10-cycloalkoxy group and/or C3- to C12-cyclo-alkenyloxy group, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, and/or a mono- and/or oligoglycosyl radical, with the proviso that at least one radical from R1 and R2 is OR11, and R3 is a radical OR11, and R4 to R7 and R10 may be identical or different and are, independently of one another, radicals which are substantially inert with respect to the UV properties.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: October 31, 2006
    Assignee: Merck Patent GmbH
    Inventors: Herwig Buchholz, Christophe Carola, Sophie Perruchon
  • Publication number: 20060210500
    Abstract: The present invention relates to formulations for topical applications comprising pigments obtainable by agitating a suspension comprising one or more inorganic pigments and silver oxide, in order to reduce undesirable side effects caused by microorganisms.
    Type: Application
    Filed: March 24, 2004
    Publication date: September 21, 2006
    Applicant: MERCK PATENT GMBH
    Inventors: Valerie Bicard-Benhamou, Herwig Buchholz, Markus Brunner
  • Publication number: 20060188591
    Abstract: The present invention relates to an plant extract from Bauhinia species with hypoglycemic activity, which is characterized in being obtained from a Bauhinia species and to a method for producing the extract and the use of the extract in the treatment of diabetes type 2.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 24, 2006
    Inventors: Herwig Buchholz, Corinna Wirth, Valerie Bicard-Benhamou, Deoclecio Carmo, Didier Mesangeau
  • Patent number: 7041652
    Abstract: The present invention relates to novel compositions containing ascorbic acid with an increased bioavailability of this vitamin. These compositions are useful as food supplements possessing preventive properties against damages of human organs, including skin, tissues and cells due to oxidative stress or damages.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: May 9, 2006
    Assignee: Merck Patent GmbH
    Inventors: Herwig Buchholz, Jerzy Meduski
  • Patent number: 7014865
    Abstract: The present invention relates to novel compositions containing a combination of the plant St. John's Wort (Hypericum perforatum L.), its extracts of active ingredients and derivatives of dihydro- and tetrahydrofolic acid. This natural formulation is useful for the treatment and prevention of depression with a better effect than the ingredient compounds alone.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: March 21, 2006
    Assignee: Merck Patent GmbH
    Inventors: Herwig Buchholz, Angela Dudda, Jerzy Meduski
  • Patent number: 7009062
    Abstract: The invention relates to a process for the preparation of flavone derivatives in which a 2-hydroxyacetophenone compound is metallated using a lithium compound at low temperatures and subsequently reacted with a keto compound, and where the ratio of the molar equivalents of lithium compound to the 2-hydroxyacetophenone compound functional groups to be metallated is from 1 to 1.2. The resultant ?-diketone compound is subsequently cyclized with warming in an acidic medium.
    Type: Grant
    Filed: January 12, 2002
    Date of Patent: March 7, 2006
    Assignee: Merck Patent GmbH
    Inventors: Herwig Buchholz, Sophie Perruchon
  • Publication number: 20060045856
    Abstract: The invention relates to a cosmetic or dermatological composition containing at least one precursor of a substance whose active form is sought for its cosmetic activity. One of the applications of the invention relates to compositions capable of rapidly imparting to the skin a color similar to that obtained on prolonged exposure to ultraviolet, solar or artificial radiation, while at the same time avoiding the drawbacks of such an exposure (erythema, burning, loss of elasticity, appearance of wrinkles, premature ageing of the skin, and the like).
    Type: Application
    Filed: September 1, 2004
    Publication date: March 2, 2006
    Inventors: Teresa Mujica, Christophe Carola, Sylvia Huber, Herwig Buchholz
  • Publication number: 20060039937
    Abstract: The invention relates to a composition having antioxidant properties comprising at least one compound of the formula I or a cosmetically, dermatologically or pharmacologically tolerated salt or derivative thereof where R1 to R4 can be identical or different and are selected from H C6-28-alkylcarboxylic acid radicals C6-28-alkenylcarboxylic acid radicals radicals of the formula II where R5-R8, independently of one another, are H, hydroxyl or C1-6-alkoxy, with the proviso that at least one of the radicals R1 to R4 is a radical of the formula II.
    Type: Application
    Filed: October 29, 2004
    Publication date: February 23, 2006
    Inventors: Teresa Mujica-Fernaudd, Christophe Carola, Marcus Brunner, Sylvia Huber, Herwig Buchholz
  • Patent number: 6903134
    Abstract: The invention relates to a cosmetic or pharmaceutical formulation comprising at least one compound of formula (I). The cosmetics or pharmaceutical products are particularly suitable for the care of the skin in protecting against oxidative stress and ageing phenomena.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: June 7, 2005
    Assignee: Merck Patent GmbH
    Inventors: Frank Pflücker, Herwig Buchholz, Ralf Rosskopf, Joachim Bünger
  • Publication number: 20050043398
    Abstract: The invention relates to the use of chrome-4-one derivatives of the formula I where R1 and R2 may be identical or different and are selected from H, —C(?O)—R7, —C(?O)—OR7, alkyl groups, alkenyl groups, hydroxyalkyl groups and/or cycloalkyl groups and/or cycloalkenyl groups, R3 is H or alkyl groups, R4 is H or OR8, R5 and R6 are selected from —H, —OH, alkyl groups, alkenyl groups and hydroxyalkyl groups, and R7 is H, alkyl groups, a polyhydroxyl compound, such as, preferably, an ascorbic acid radical or glycosidic radicals, and R8 is H or alkyl groups, where at least two of the substituents R1, R2 and R4—R6 are different from H or at least one substituent from R1 and R2 is —C(?O)—R7 or —C(?O)—OR7, for the care, preservation or improvement of the general state of the skin or hair.
    Type: Application
    Filed: August 18, 2004
    Publication date: February 24, 2005
    Inventors: Christophe Carola, Herwig Buchholz, Sylvia Huber, Ralf Rosskopf
  • Publication number: 20050019426
    Abstract: The present invention relates to a composition comprising an aqueous or hydroalcoholic extract of bauhinia and to the use of an aqueous or hydroalcoholic extract of bauhinia for the preparation of a composition for the care, preservation or improvement of the general state of the skin or hair, for the prophylaxis or prevention of human skin or human hair ageing processes and for the prophylaxis and/or treatment of diseases associated with skin ageing.
    Type: Application
    Filed: June 28, 2004
    Publication date: January 27, 2005
    Inventors: Corinna Wirth, Herwig Buchholz
  • Publication number: 20040220182
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: April 28, 2004
    Publication date: November 4, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Wilfried Rautenberg, Christian Sirrenberg
  • Patent number: 6812215
    Abstract: Compositions and pharmaceutical compositions are described which comprise: a component A comprising one or more flavonol glycosides, a component B comprising one or more tetrahydrofolic acid compounds, a component C comprising one or more calcium supplements, and a component D comprising one or more magnesium supplements. Methods of using such compositions and pharmaceutical compositions to treat and/or prevent osteoporosis and/or an inflammatory joint disease are also described.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: November 2, 2004
    Assignee: Merck Patent Gesellschaft mit beschränkter Haftung
    Inventors: Herwig Buchholz, Jerzy Meduski
  • Publication number: 20040202624
    Abstract: The invention relates to compounds of the formula I 1
    Type: Application
    Filed: April 28, 2004
    Publication date: October 14, 2004
    Inventors: Frank Pfluecker, Joachim Buenger, Hans-Juergen Driller, Herwig Buchholz, Ralf Rosskopf
  • Publication number: 20040176440
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: December 2, 2003
    Publication date: September 9, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Publication number: 20040170714
    Abstract: The present invention relates to an plant extract from Bauhinia species with hypoglycaemic activity, which is characterized in being obtained from a Bauhinia species and to a method for producing the extract and the use of the extract in the treatment of diabetes type 2.
    Type: Application
    Filed: January 27, 2004
    Publication date: September 2, 2004
    Inventors: Herwig Buchholz, Corinna Wirth, Valerie Bicard-Benhamou, Deoclecio Carmo, Didier Mesangeau
  • Publication number: 20040138464
    Abstract: Novel compounds of the formula I 1
    Type: Application
    Filed: December 2, 2003
    Publication date: July 15, 2004
    Inventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
  • Publication number: 20040091433
    Abstract: The invention relates to a preparation having light-protection properties comprising at least one compound of the formula I 1
    Type: Application
    Filed: July 18, 2003
    Publication date: May 13, 2004
    Applicant: Merck Patent GmbH
    Inventors: Herwig Buchholz, Christophe Carola, Sophie Perruchon
  • Publication number: 20040067894
    Abstract: The invention relates to a preparation having antioxidant properties, comprising at least one compound of the formula I 1
    Type: Application
    Filed: September 23, 2003
    Publication date: April 8, 2004
    Applicant: Merck Patent GmbH
    Inventors: Christophe Carola, Sophie Perruchon, Herwig Buchholz