Abstract: In this method, an oligonucleotide is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R1, Y, Base, Z, Ar, R2, R3 and n are each as defined in Claim 1]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3?-direction but also in the 5?-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

Abstract: An electric wire connection portion of a crimp terminal includes a core wire crimping portion crimped to a core wire at an end of an electric wire, a bottom of the core wire crimping portion includes a recess, formed by causing a part of a supported surface on an outer wall surface side to be recessed to an inner wall surface side and a protrusion protruding from the inner wall surface toward the core wire at the end of the electric wire by the recess of the recess, and ends of the recess and the protrusion on a side opposite to the sheath crimping portion side are inclined to the sheath crimping portion side as being directed from the outer wall surface side to the inner wall surface side.

Abstract: In this method, an oligonucleotide is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R1, Y, Base, Z, Ar, R2, R3 and n are each as defined in Claim 1]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method cars dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3?-direction but also in the 5?-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

Abstract: Technologies for indirectly calling vector functions include a compute device that includes a memory device to store source code and a compiler module. The compiler module is to identify a set of declarations of vector variants for scalar functions in the source code, generate a vector variant address map for each set of vector variants, generate an offset map for each scalar function, and identify, in the source code, an indirect call to the scalar functions, wherein the indirect call is to be vectorized. The compiler module is also to determine, based on a context of the indirect call, a vector variant to be called and store, in object code and in association with the indirect call, an offset into one of the vector variant address maps based on (i) the determined vector variant to be called and (ii) the offset map that corresponds to each scalar function.

Abstract: An electric wire connection portion includes a second core wire crimping portion) in which a pair of barrel pieces is wound around a core wire while widening a distance with respect to the bottom in a sandwiching direction of the core wire as being directed from a first core wire crimping portion side to the sheath crimping portion side. A boundary crimping area Tc arranged at a boundary part between a second core wire crimping portion and the sheath crimping portion includes a plurality of coupling crimping portions each of which connect two crimping portions among crimping portions having different angles with respect to a drawing direction of the electric wire from the crimp terminal between the second core wire crimping portion side and the sheath crimping portion side in at least an overlapping area.

Abstract: An electric wire connection portion of a crimp terminal includes a core wire crimping portion crimped to a core wire at an end of an electric wire, a bottom of the core wire crimping portion includes a recess, formed by causing a part of a supported surface on an outer wall surface side to be recessed to an inner wall surface side and a protrusion protruding from the inner wall surface toward the core wire at the end of the electric wire by the recess of the recess, and ends of the recess and the protrusion on a side opposite to the sheath crimping portion side are inclined to the sheath crimping portion side as being directed from the outer wall surface side to the inner wall surface side.

Abstract: According to a first aspect, efficient data transfer operations can be achieved by: decoding by a processor device, a single instruction specifying a transfer operation for a plurality of data elements between a first storage location and a second storage location; issuing the single instruction for execution by an execution unit in the processor; detecting an occurrence of an exception during execution of the single instruction; and in response to the exception, delivering pending traps or interrupts to an exception handler prior to delivering the exception.

Abstract: According to a first aspect, efficient data transfer operations can be achieved by: decoding by a processor device, a single instruction specifying a transfer operation for a plurality of data elements between a first storage location and a second storage location; issuing the single instruction for execution by an execution unit in the processor; detecting an occurrence of an exception during execution of the single instruction; and in response to the exception, delivering pending traps or interrupts to an exception handler prior to delivering the exception.

Abstract: In one example, a system for generating vector based selection control statements can include a processor to determine a vector cost of the selection control statement is below a scalar cost and determine the selection control statement is to be executed in a sorted order based on dependencies between branch instructions of the selection control statement. The processor can also determine a program ordering of labels of the selection control statement does not match a mathematical ordering of the labels and execute the selection control statement with a vector of values, wherein the selection control statement is to be executed based on a jump table and a sorted unique value technique, wherein the sorted unique value technique comprises selecting at least one of the plurality of branch instructions from the jump table.

Abstract: According to a first aspect, efficient data transfer operations can be achieved by: decoding by a processor device, a single instruction specifying a transfer operation for a plurality of data elements between a first storage location and a second storage location; issuing the single instruction for execution by an execution unit in the processor; detecting an occurrence of an exception during execution of the single instruction; and in response to the exception, delivering pending traps or interrupts to an exception handler prior to delivering the exception.

Abstract: According to a first aspect, efficient data transfer operations can be achieved by: decoding by a processor device, a single instruction specifying a transfer operation for a plurality of data elements between a first storage location and a second storage location; issuing the single instruction for execution by an execution unit in the processor; detecting an occurrence of an exception during execution of the single instruction; and in response to the exception, delivering pending traps or interrupts to an exception handler prior to delivering the exception.

Abstract: An electric wire with a terminal includes an electric wire, and a crimping terminal including an electric wire connection portion crimped by being wound around a core and a cover of the electric wire, a diameter expansion portion which contains a water stop member covering a tip end portion of the core and sealing a gap between the core and the electric wire connection portion is provided in an end portion of the electric wire connection portion on a tip end side of the core, and a sectional area of the diameter expansion portion is greater than a sectional area at a portion on the base end side of the core with respect to the diameter expansion portion.

Abstract: A method of manufacturing a crimping terminal includes a punching process of punching out a crimping terminal from a flat-plate-shaped metal base material, an attaching process of attaching a sheet-like water stop member to a wire connection portion being a portion in the crimping terminal that is to be crimped onto a wire, and a bending process of bending the wire connection portion to which the water stop member is attached. The wire connection portion may integrally cover a core wire and a covering of the wire by being crimped onto the wire.

Abstract: A wire harness manufacturing system includes a display unit, a wire cutting machine that draws an electric wire from a wire feed reel and cuts the electric wire to a predetermined length, a control unit that directs the display unit to display a wire laying image and wire work identification information for identifying a work regarding each electric wire, the wire laying image including a plurality of wire images showing the plurality of electric wire in the laid state and the wire work identification information being displayed in the vicinity of the corresponding wire image, and a memory unit that stores the wire laying image and work instruction information so as to correspond to the wire work identification information, the work instruction information including cut length of the electric wire. The control unit sends the cut length information to the wire cutting machine.

Abstract: An objective is to provide screening methods for substances having an activity of promoting maturation into hemocytes. It was revealed that in the maturation process of erythrocytes and platelets, RP S19 multimers are released to the outside of the cell and act on the C5a receptors of erythroblasts and megakaryocytes, thereby causing maturation of erythroblasts and megakaryocytes to erythrocytes and platelets. Based on such findings, the present invention provides methods of screening for substances having an activity of promoting maturation into hemocytes by targeting the RP S19 multimers and C5a receptors. The screening methods of the present invention can detect hemocyte maturation using an increase of the R4 RGS family as an indicator. Furthermore, the present invention provides agents for promoting hemocyte maturation, which comprise RP S19 multimers and a substance having an activity of promoting maturation into hemocytes as useful components.

Abstract: A terminal crimping device includes a terminal feeding device, a crimping device and an electric-wire holding mechanism that holds an electric wire with an end portion of the electric wire placed above an electric-wire connecting portion of a crimp terminal. The electric-wire holding mechanism includes an upper surface of a terminal cutting body, on which the electric wire is placed, and an electric-wire presser that is moved downward toward the upper surface and presses and thereby holds the electric wire placed on the upper surface. Between the electric-wire placing portion and a lower surface of the electric-wire presser, an electric-wire holding space is formed that inclines in the same direction to a declining direction in which the end portion of the electric wire is declined in association with downward move of the second die toward the first die, and that holds the electric wire in a thus inclined state.

Abstract: Methods to improve optimization of compilation are presented. In one embodiment, a method includes identifying one or more optimization speculations with respect to a code region and speculatively performing transformation on an intermediate representation of the code region in accordance with an optimization speculation. The method includes generating an advice message corresponding to the optimization speculation and displaying the advice message if the optimization speculation results in an improved compilation result.

Abstract: According to a first aspect, efficient data transfer operations can be achieved by: decoding by a processor device, a single instruction specifying a transfer operation for a plurality of data elements between a first storage location and a second storage location; issuing the single instruction for execution by an execution unit in the processor; detecting an occurrence of an exception during execution of the single instruction; and in response to the exception, delivering pending traps or interrupts to an exception handler prior to delivering the exception.

Abstract: A trim device includes a trim cylinder, a piston, a piston rod and a support member. The piston is slidable inside the trim cylinder, in the axial direction of the trim cylinder. The piston rod is connected with the piston and moves in the axial direction of the trim cylinder following the movement of the piston. The support member is slidable relative to the piston rod and arranged to support the piston rod so that the piston rod's axial center can become tilted with respect to the axial center of the cylinder.

Abstract: An objective is to provide screening methods for substances having an activity of promoting maturation into hemocytes. It was revealed that in the maturation process of erythrocytes and platelets, RP S19 multimers are released to the outside of the cell and act on the C5a receptors of erythroblasts and megakaryocytes, thereby causing maturation of erythroblasts and megakaryocytes to erythrocytes and platelets. Based on such findings, the present invention provides methods of screening for substances having an activity of promoting maturation into hemocytes by targeting the RP S19 multimers and C5a receptors. The screening methods of the present invention can detect hemocyte maturation using an increase of the R4 RGS family as an indicator. Furthermore, the present invention provides agents for promoting hemocyte maturation, which comprise RP S19 multimers and a substance having an activity of promoting maturation into hemocytes as useful components.