Abstract: The method for measuring the concentration of the measuring object uses a sensor chip comprising an optical waveguide layer and an antibody immobilized layer formed on the surface of the optical waveguide layer, which comprises immobilizing the measuring object and an enzyme-labeled antibody labeled with a labeling enzyme on the antibody immobilized layer of the sensor chip having an immobilized antibody, producing a color-developing and precipitating enzyme reaction product by allowing to react a coloring reagent with the labeling enzyme on the antibody immobilized layer to precipitate the enzyme reaction product on the antibody immobilized layer, allowing to totally reflect a light impinged on the sensor chip from the outside at an interface between the optical waveguide layer and the antibody immobilized layer, and observing to a physical value of the totally reflected light.

Abstract: An optical waveguide type iontophoresis sensor chip has a substrate having a first hinged plate and a second hinged plate, an optical waveguide plate connected to the first hinged plate and positioned over a first opening delineated in the first hinged plate, and a gel layer fixed on the second hinged plate and covering a second opening delineated in the second hinged plate and configured to contact with the optical waveguide plate through the first opening in case that the substrate is folded.

Abstract: The method for measuring the concentration of the measuring object uses a sensor chip comprising an optical waveguide layer and an antibody immobilized layer formed on the surface of the optical waveguide layer, which comprises immobilizing the measuring object and an enzyme-labeled antibody labeled with a labeling enzyme on the antibody immobilized layer of the sensor chip having an immobilized antibody, producing a color-developing and precipitating enzyme reaction product by allowing to react a coloring reagent with the labeling enzyme on the antibody immobilized layer to precipitate the enzyme reaction product on the antibody immobilized layer, allowing to totally reflect a light impinged on the sensor chip from the outside at an interface between the optical waveguide layer and the antibody immobilized layer, and observing to a physical value of the totally reflected light.

Abstract: An optical waveguide sensor for glucose measurement comprises a substrate, a first optical waveguide layer formed on a surface of the substrate, an entrance grating and an exit grating which are formed contacting with the first optical waveguide layer and being spaced from each other, a second optical waveguide layer located between the entrance grating and the exit grating while being in contact with the first optical waveguide layer, the second optical waveguide layer having a higher refractive index than that of the first optical waveguide layer, and a functioning layer containing an enzyme and a coloring reagent which is formed on the second optical waveguide layer.

Abstract: An optical waveguide type iontophoresis sensor chip has a substrate having a first hinged plate and a second hinged plate, an optical waveguide plate connected to the first hinged plate and positioned over a first opening delineated in the first hinged plate, and a gel layer fixed on the second hinged plate and covering a second opening delineated in the second hinged plate and configured to contact with the optical waveguide plate through the first opening in case that the substrate is folded.

Abstract: An optical biosensor has a total reflection plate so as to totally internally reflect and transmit an incident light, a first grating and a second grating disposed separately on the total reflection plate, and a sensing membrane that is containing an enzyme and a chromogenic reagent and is sandwiched by the first and second gratings on the total reflection plate.

Abstract: An optical waveguide sensor for glucose measurement comprises a substrate, a first optical waveguide layer formed on a surface of the substrate, an entrance grating and an exit grating which are formed contacting with the first optical waveguide layer and being spaced from each other, a second optical waveguide layer located between the entrance grating and the exit grating while being in contact with the first optical waveguide layer, the second optical waveguide layer having a higher refractive index than that of the first optical waveguide layer, and a functioning layer containing an enzyme and a coloring reagent which is formed on the second optical waveguide layer.

Abstract: An optical waveguide sensor for glucose measurement comprises a substrate, a first optical waveguide layer formed on a surface of the substrate, an entrance grating and an exit grating which are formed contacting with the first optical waveguide layer and being spaced from each other, a second optical waveguide layer located between the entrance grating and the exit grating while being in contact with the first optical waveguide layer, the second optical waveguide layer having a higher refractive index that that of the first optical waveguide layer, and a functioning layer containing an enzyme and a coloring reagent which is formed on the second optical waveguide layer.

Abstract: An antigen measuring device has an antibody chip. The antibody chip has a substrate. A pair of gratings are formed on the substrate. An antibody-fixed layer surrounded by a wall is formed between the gratings. A light emitting element emits a light beam toward the first grating. A light receiving element receives the light beam which propagates through the substrate under the antibody-fixed layer and is outputfrom the second grating.

Abstract: An ink jet head includes a nozzle plate having a nozzle hole and a film having at least one of a water repellent function and an oil repellent function formed on one plate face thereof. The film includes a metal oxide and fluorine based resin.

Abstract: An optical waveguide sensor for glucose measurement comprises a substrate, a first optical waveguide layer formed on a surface of the substrate, an entrance grating and an exit grating which are formed contacting with the first optical waveguide layer and being spaced from each other, a second optical waveguide layer located between the entrance grating and the exit grating while being in contact with the first optical waveguide layer, the second optical waveguide layer having a higher refractive index that that of the first optical waveguide layer, and a functioning layer containing an enzyme and a coloring reagent which is formed on the second optical waveguide layer.

Abstract: A method of manufacturing an ink jet head having a nozzle plate which has a nozzle hole and has a film having at least one of a water repellent function and an oil repellent function formed on one plate face thereof, the method comprises a step of providing the film on one plate face of the nozzle plate, and a step of etching the nozzle plate from the other plate face side, followed by removing the film adhered to the inner periphery face of the nozzle hole.