Abstract: The present invention provides a process for producing biologically active recombinant yeast protein disulfide isomerase, which includes the steps of: a) deleting, substituting, or adding one or more bases in a region encoding an endoplasmic reticulum retention signal in a gene encoding protein disulfide isomerase of yeast to modify the gene so as not to encode part or all of the endoplasmic reticulum retention signal; b) incorporating the modified gene into an expression vector; c) transforming host cells with the expression vector; and d) culturing the host cells transformed with the expression vector in a culture medium kept at a nearly neutral pH, thereby causing protein disulfide isomerase to be secreted in an active state outside the host cells. According to the process of the invention, recombinant yeast protein disulfide isomerase can be secreted in a large amount in a biologically active state into a culture medium, and can be collected by a simple purification method.

Abstract: The diagnosis method of deterioration of electric power cable is that which diagnoses the deterioration accurately without a especial effort to reduce the harmonics in an electric power source equipment for test. Loss current component, which is obtained by rejecting the capacitive component of frequency f1 contained in the total current flowing in the insulation of the electric power cable, when superimposing a first voltage V1 of frequency f1 and a second voltage V2 of frequency f2 (V1≧V2) to an electric power cable, is measured. Further the current components and the frequency components contained in the current is investigated. The deterioration diagnosis is implemented by frequency components excepting the frequency f1, f2 and the their harmonic.

Abstract: The present invention is directed to a process for preparing an exo-methylenepenam compound wherein a cephem compound is reduced with a metal having a standard oxidation-reduction potential of up to −0.3 (V/SCE) in an amount of at least one mole per mole of the cephem compound and with a metal compound having a higher standard oxidation reduction potential than the metal and in an amount of 0.

Abstract: A short arc lamp with a reflection surface integrated in one piece, and in which, even when the lamp is being operated over a long time, neither a reduction of the reflection factor nor breakage of the lamp main part occurs is achieved.

Abstract: A carrier and a polishing apparatus are designed to improve the mass producibility of wafers while using a retainer ring formed by a soft material. A rubber sheet 4 is bonded to the bottom surface of a carrier body 2 of the carrier 1 to define a pressure chamber R, a retainer ring 13 formed by a soft material such as EG is bonded to the bottom surface of the sheet 4. A margin block 40 is provided projecting out from the bottom side of the sheet 4, and the thickness of the retainer ring 13 is set to be substantially equal to the sum of the thickness L1 of the margin block 40 and the thickness L2 of the wafer W.

Abstract: A card dispensing device has a mechanism for preventing double feeding of cards. The double feed preventing mechanism can be card attitude correction rollers, which adjoin the leading edges of the cards within the card dispensing unit and thickness screws to regulate the vertical dimension of the card feed route. The double feed preventing mechanism can be a plate having a leading edge extending into the card feed route to regulate the vertical dimension of the card feed route.

Abstract: A card-dispensing device has a mechanism for forcibly modifying the attitude of the slide during the forward run of the slide from a horizontal attitude in which the slide is pushing a card forward to an attitude which is inclined through a fixed angle, and then forcibly returned to its initial horizontal attitude during the backward run.

Abstract: An LED array composed of a plurality of LEDs is disposed on either side of a signal interconnection board, while metal plates are disposed on the other side of the signal interconnection board as positive and negative power source lines for driving the LEDs, respectively, and a capacitor is provided between the positive metal plate for power supply and the negative metal plate for power supply. As a result, the LED array in which an output light is not lowered in power, no variations in light output arises in every LEDs, and all the LEDs can be turned on simultaneously is provided.

Abstract: It is an object of the invention to provide a LED array, in which faults of all the diodes can be instantaneously detected, even when an optical printer is operating, and various kinds of faults of the LEDs can be discriminated. In the LED array comprising plural LEDs arranged along a lone, each LED is provided with a comparator, which compares a terminal voltage of the LED with a variable reference voltage. The kind of fault of the LED can be discriminated on the basis of a relation between the reference voltage applied to the comparator and an output voltage thereof.

Abstract: A carrier comprising a disk-shaped body portion having fluid circulation holes, a ring-shaped diaphragm portion expanding outward from the outer peripheral surface of the body portion and having pliability, a ring-shaped edge portion projecting at least downward from an outer edge portion of the diaphragm portion and having an inner diameter of at least an outer diameter of a work piece, a pliable sheet having an outer peripheral portion affixed air tightly to a bottom end portion of said edge portion, the back surface of the sheet defining a single pressure chamber communicating with the fluid circulation holes, and a ring-shaped member surrounding the work piece affixed to the bottom surface of the sheet.

Abstract: The present invention provides a process for preparing an exo-methylenepenam compound represented by the general formula (5) characterized in that a &bgr;-lactam halide compound represented by the general formula (2) is subjected to an electroreduction process to obtain the exo-methylenepenam compound.

Abstract: A 4-tetrahydropyridylpyrimidine compound represented by formula (I): wherein Ar represents a phenyl group substituted with 1 to 3 substituents selected from a halogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, and a trifluoromethyl group, a phenyl group, a thienyl group or a furanyl group; R1 represents a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, an amino group or an amino group substituted with 1 or 2 alkyl groups having 1 to 5 carbon atoms; R2 represents an alkyl group having 1 to 5 carbon atoms, a cycloalkylalkyl group having 4 to 7 carbon atoms, an alkenyl group having 2 to 5 carbon atoms or an alkynyl group having 2 to 5 carbon atoms; and X1, X2, and X3, which may be the same or different, each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, an alkylthio group having 1 to 5 carbon atoms, an amino group or an amino group substituted with 1 or

Abstract: An optical write head operable in high speeds is provided with better printing results. The optical write head is arranged by an LED array constructed of a plurality of LEDs arrayed in a line form, one shift register used to store thereinto pixel data for a front half portion of this LED array, and the other shift register used to store thereinto pixel data for a rear half portion of this LED array. The optical write head is further arranged by registers for latching parallel pixel data outputted from these shift registers, and a driving circuit for simultaneously driving the LEDs employed in the LED array in response to patterns of the pixel data outputted from the registers when a control signal is inputted.

Abstract: A process for preparing an allenyl .beta.-lactam compound represented by the formula (4), characterized by reacting the hydroxyl group of a .beta.-lactam compound represented by the formula (1) with a reactive functional group derivative of sulfonic acid represented by the formula (2) to convert the compound of the formula (1) to a .beta.-lactam compound represented by the formula (3), thereafter reacting the resulting .beta.-lactam compound with a basic anion exchange resin of the type having a tertiary organic base fixed to the resin and isolating the resulting allenyl .beta.

Abstract: A card-dispensing device has a mechanism for forcibly modifying the attitude of the slide during the forward run of the slide from a horizontal attitude in which the slide is pushing a card forward to an attitude which is inclined through a fixed angle, and then forcibly returned to its initial horizontal attitude during the backward run.

Abstract: The present invention provides a process for preparing an exo-methylenepenam compound represented by the general formula (5) characterized in that a .beta.-lactam halide compound represented by the general formula (2) is reduced with a metal having a standard oxidation-reduction potential of up to -0.3 (V/SCE) in an amount of at least one mole per mole of the halide compound and with a metal compound having a higher standard oxidation-reduction potential than the metal in an amount of 0.0001 to 10 moles per mole of the halide compound, or is subjected to an electroreduction process to obtain the exo-methylenepenam compound.

Abstract: A magnetic head for recording information on a recording disk which has a head body that has a sliding sole which contacts the recording disk. The head body is supported by a three-piece leaf spring which has one end connected to a support and the other end connected to the head body. The support member includes a stopper which engages the end of the second portion of the leaf spring so as to control the position of the head body.

Abstract: A carrier and CMP apparatus which improve the uniformity of polishing in a wafer or other workpiece and increase the margin of the amount of wear of the retainer ring to improve the operating rate of the CMP apparatus. A carrier 1 is constituted by a housing 10, a carrier base 11, a retainer ring 12, a sheet supporter 13, a hard sheet 18, and a soft backing sheet 19. The sheet supporter 13 is formed by a supporter body portion 14 having an air opening 14a communicating with an air outlet/inlet 11b of the carrier base 11, a flexible diaphragm 15, and an edge ring 16. Therefore, a wafer W is uniformly pressed by the air pressure in the pressure chamber R and fluctuation in the force pressing against the outer peripheral rim of the wafer W caused by the wear of the retainer ring 12 is countered by the diaphragm 15.

Abstract: A process for preparing a .beta.-lactam halide compound represented by the formula (2) characterized by halogenating the allenyl group of an allenyl .beta.-lactam compound represented by the formula (1) with a cupric halide and a metal halide to obtain the .beta.-lactam halide compound ##STR1## wherein R.sup.1 is a hydrogen atom or amino or protected amino, R.sup.2 is a hydrogen atom, halogen atom, lower alkoxyl, lower acyl, or lower alkyl having a hydroxyl group or protected hydroxyl group as a substituent, R.sup.3 is a hydrogen atom or carboxylic acid protecting group, and R.sup.4 is a hydrocarbon group which may have a substituent, or the group --S--S(O)n-Ar, n being 0 to 2, Ar being aryl which may have a substituent ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same as defined above, X and Y are each halogen atom.

Abstract: The present invention provides a process for preparing an allenyl .beta.-lactam compound represented by the formula (II) or a process for preparing a 3-halocephem compound of the formula (III) by altering the reaction conditions with use of a .beta.-lactam halide compound represented by the formula (I) serving as the starting material ##STR1## wherein R.sub.1 is a hydrogen atom, amino or protected amino, R.sub.2 is aryl which may have a substituent, n is 0 to 2, R.sub.3 is a hydrogen atom or carboxylic acid protective group, X is a halogen atom, and Y is a halogen atom or a leaving group ##STR2## wherein R.sub.1, R.sub.2, n and R.sub.3 are as defined above ##STR3## wherein R.sub.1, R.sub.3 and X are as defined above.