Patents by Inventor Hiroaki Matsuyama
Hiroaki Matsuyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150343030Abstract: The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/100 ml and not more than 150 mg/100 ml, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.Type: ApplicationFiled: July 31, 2012Publication date: December 3, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
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Publication number: 20150297690Abstract: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and lactoperoxidase and/or lactoperoxidase hydrolysate, in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.3 to 20.Type: ApplicationFiled: July 31, 2012Publication date: October 22, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko OHMACHI, Hiroaki MATSUYAMA, Yoshikazu MORITA, Yuko ISHIDA, Takayuki NARA, Ken KATO, Atsushi SERIZAWA
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Publication number: 20150258184Abstract: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.Type: ApplicationFiled: July 31, 2012Publication date: September 17, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa
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Publication number: 20150230485Abstract: The invention relates to a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.006 to 1.7.Type: ApplicationFiled: July 31, 2012Publication date: August 20, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
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Publication number: 20150230486Abstract: The invention relates to a cheese includes angiogenin and/or angiogenin hydrolysate in an amount of 6.5 mg/100 g to 160 mg/100 g, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.02 to 1.6.Type: ApplicationFiled: July 31, 2012Publication date: August 20, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
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Publication number: 20150224178Abstract: The invention relates to a powdered milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 1.4 to 24 mg/15 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.35 to 10.Type: ApplicationFiled: July 31, 2012Publication date: August 13, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
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Publication number: 20150182557Abstract: The invention relates to provide a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.Type: ApplicationFiled: July 31, 2012Publication date: July 2, 2015Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
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Patent number: 8821853Abstract: An anti-fatty liver agent containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient is provided. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage or food containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient. Methods of treating fatty liver in a subject by administering a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri are also provided.Type: GrantFiled: January 8, 2014Date of Patent: September 2, 2014Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Hiroshi Kawakami, Hiroaki Matsuyama, Masao Sato, Katsumi Imaizumi
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Publication number: 20140140972Abstract: An anti-fatty liver agent containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient is provided. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage or food containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient. Methods of treating fatty liver in a subject by administering a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri are also provided.Type: ApplicationFiled: January 8, 2014Publication date: May 22, 2014Applicant: MEGMILK SNOW BRAND Co., Ltd.Inventors: Hiroshi KAWAKAMI, Hiroaki MATSUYAMA, Masao SATO, Katsumi IMAIZUMI
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Patent number: 8647619Abstract: It is intended to provide an osteogenesis promoter capable of promoting osteogenesis by promoting the differentiation of osteoblasts, and foods, drinks, drugs or feeds for promoting osteogenesis. Namely, an osteogenesis promoter capable of promoting osteogenesis by promoting the differentiation of osteoblasts which comprises, as the active ingredient, lactoperoxidase and/or a digestion product obtained by digesting lactoperoxidase with a protease such as trypsin; and foods, drinks, drugs or feeds for promoting osteogenesis containing lactoperoxidase and/or its digestion product.Type: GrantFiled: October 5, 2009Date of Patent: February 11, 2014Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Mutsumi Motouri, Hiroaki Matsuyama, Yoshikazu Morita, Atsushi Serizawa, Hiroshi Kawakami
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Patent number: 8642318Abstract: Disclosed is an anti-fatty liver agent comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage/food comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient.Type: GrantFiled: July 24, 2007Date of Patent: February 4, 2014Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Hiroshi Kawakami, Hiroaki Matsuyama, Masao Sato, Katsumi Imaizumi
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Patent number: 8580740Abstract: A milk protein fraction having following properties (1) to (4) is excellent in bone resorption inhibitory effect, and is useful for preventing or treating bone diseases: (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein having a molecular weight of 12,000 to 16,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 18 to 20 wt % in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.7 to 0.9; and (4) the milk protein fraction has a bone resorption inhibitory effect.Type: GrantFiled: October 28, 2008Date of Patent: November 12, 2013Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Atsushi Serizawa, Yoshikazu Morita, Daisuke Uetsuji, Aiko Ono, Hiroaki Matsuyama, Satoshi Higurashi
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Patent number: 8547510Abstract: A liquid crystal display panel for displaying an image by controlling an orientation direction of a liquid crystal mixture with respect to each pixel, includes a first common electrode which is formed on a first substrate; a second common electrode which is formed on a second substrate and includes a predetermined opening; and a pixel electrode which is formed on the second substrate, wherein the first substrate faces the second substrate so that the liquid crystal mixture with positive dielectric anisotropy is sandwiched between the first common electrode and the second common electrode, and wherein the orientation direction of the liquid crystal mixture changes mainly in a face parallel to the substrate according to an electric field generated from electric potential of the first common electrode, the second common electrode, and the pixel electrode.Type: GrantFiled: August 18, 2008Date of Patent: October 1, 2013Assignee: NLT Technologies, Ltd.Inventors: Hiroaki Matsuyama, Takahiko Watanabe
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Publication number: 20130225497Abstract: A skin collagen production-promoting agent includes a milk protein fraction having following properties (a) to (c) as an active ingredient: (a) being derived from milk, (b) containing proteins having a molecular weight determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of 6000 to 150,000 daltons, and (c) containing 12 to 14 wt % of basic amino acids with respect to the constituent amino acid composition, and having a basic amino acid/acidic amino acid ratio of 0.5 to 0.7.Type: ApplicationFiled: September 29, 2011Publication date: August 29, 2013Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Ken Kato, Aiko Ono, Hiroshi Ueno, Noriko Ueda, Hiroaki Matsuyama
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Publication number: 20130225501Abstract: Skin quality is improved by orally administering a cystatin and/or a degraded product of cystatin in an amount of 10 ?g/day or more per adult, or applying a composition that includes a cystatin and/or a degraded product of cystatin in an amount of 0.001 to 2 wt % based on a total amount of the composition.Type: ApplicationFiled: September 29, 2011Publication date: August 29, 2013Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Ken Kato, Aiko Ono, Hiroshi Ueno, Noriko Ueda, Hiroaki Matsuyama
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Patent number: 8420599Abstract: Disclosed is a bone-reinforcing agent which comprises a milk protein fraction having the following properties (1) to (4): (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein component having a molecular weight of 6,000 to 150,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 12 to 14 wt % in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.5 to 0.7; and (4) the milk protein fraction has an activity of accelerating the calcification in an osteoblast.Type: GrantFiled: October 28, 2008Date of Patent: April 16, 2013Assignee: MegMilk Snow Brand Co., Ltd.Inventors: Atsushi Serizawa, Yoshikazu Morita, Daisuke Uetsuji, Aiko Ono, Hiroaki Matsuyama, Satoshi Higurashi
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Patent number: 8207131Abstract: The present invention relates to a peptide that is derived from a milk protein and has an antioxidative effect, an antioxidant that includes the peptide as an active ingredient, and an antioxidative food, drink, or feed that includes the peptide. The present invention also relates to a peptide that is derived from a milk protein and has an adiponectin production promotion effect, an adiponectin production promoter that includes the peptide as an active ingredient, and an adiponectin production promotion food, drink, or feed that includes the peptide. The present invention further relates to a blood adiponectin level increase promotion and/or decrease inhibition agent that includes a component contained in cheese as an active ingredient, and a blood adiponectin level increase promotion and/or decrease inhibition food or drink that includes a component contained in cheese.Type: GrantFiled: April 25, 2007Date of Patent: June 26, 2012Assignee: Megmilk Snow Brand Co., Ltd.Inventors: Yukiko Kunieda, Satoshi Higurashi, Mutsumi Motouri, Hiroaki Matsuyama, Atsushi Serizawa, Hiroshi Kawakami
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Publication number: 20120094915Abstract: To provide anti-mental fatigue drugs as well as foods, beverages, and fodders that can be taken daily and effective for relieving mental stress and inducing relaxation by intake. An anti-mental fatigue drug containing iron-binding lactoferrin as an active ingredient and foods, beverages, and fodders containing the drug.Type: ApplicationFiled: April 8, 2010Publication date: April 19, 2012Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Ran Emilie Yoshise, Hiroaki Matsuyama, Yukio Kadooka
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Publication number: 20120077780Abstract: The present disclosure relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a fat accumulation inhibitor for a fat cell which includes a milk-derived phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of inhibiting a visceral fat accumulation in a subject, which includes administering the visceral fat accumulation inhibitor which includes a sphingosine-containing phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which includes administering an agent which includes a sphingosine-containing phospholipid as an active ingredient to the blood. The present disclosure also relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a milk-derived phospholipid to a subject.Type: ApplicationFiled: September 22, 2011Publication date: March 29, 2012Inventors: Reo Tanaka, Tomoyuki Isogai, Yuko Haruta, Susumu Miura, Ken Kato, Toshimitsu Yoshioka, Hiroshi Kawakami, Satoshi Higurashi, Hiroaki Matsuyama
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Publication number: 20120009165Abstract: Disclosed is an agent for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, or a food, beverage or animal feed for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, which comprises a culture or cell of a lactic acid bacterium belonging to the genus Lactobacillus, particularly Lactobacillus gasseri or Lactobacillus helveticus as an active ingredient. Also disclosed is a visceral fat accumulation inhibitor or a food or beverage for inhibiting the accumulation of a visceral fat, which comprises a culture or cell of Lactobacillus helveticus as an active ingredient.Type: ApplicationFiled: September 19, 2011Publication date: January 12, 2012Applicant: MEGMILK SNOW BRAND CO., LTD.Inventors: Hiroshi KAWAKAMI, Satoshi HIGURASHI, Hiroaki MATSUYAMA