Patents by Inventor Hiroaki Matsuyama

Hiroaki Matsuyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150343030
    Abstract: The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/100 ml and not more than 150 mg/100 ml, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
    Type: Application
    Filed: July 31, 2012
    Publication date: December 3, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
  • Publication number: 20150297690
    Abstract: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and lactoperoxidase and/or lactoperoxidase hydrolysate, in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.3 to 20.
    Type: Application
    Filed: July 31, 2012
    Publication date: October 22, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko OHMACHI, Hiroaki MATSUYAMA, Yoshikazu MORITA, Yuko ISHIDA, Takayuki NARA, Ken KATO, Atsushi SERIZAWA
  • Publication number: 20150258184
    Abstract: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.
    Type: Application
    Filed: July 31, 2012
    Publication date: September 17, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa
  • Publication number: 20150230485
    Abstract: The invention relates to a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.006 to 1.7.
    Type: Application
    Filed: July 31, 2012
    Publication date: August 20, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
  • Publication number: 20150230486
    Abstract: The invention relates to a cheese includes angiogenin and/or angiogenin hydrolysate in an amount of 6.5 mg/100 g to 160 mg/100 g, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.02 to 1.6.
    Type: Application
    Filed: July 31, 2012
    Publication date: August 20, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
  • Publication number: 20150224178
    Abstract: The invention relates to a powdered milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 1.4 to 24 mg/15 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.35 to 10.
    Type: Application
    Filed: July 31, 2012
    Publication date: August 13, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
  • Publication number: 20150182557
    Abstract: The invention relates to provide a fermented milk product includes angiogenin and/or angiogenin hydrolysate in an amount of 0.9 mg/100 g to 150 mg/100 g, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
    Type: Application
    Filed: July 31, 2012
    Publication date: July 2, 2015
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Aiko Ohmachi, Hiroaki Matsuyama, Yoshikazu Morita, Yuko Ishida, Takayuki Nara, Ken Kato, Atsushi Serizawa, Hiroshi Ueno, Hiroshi Urazono
  • Patent number: 8821853
    Abstract: An anti-fatty liver agent containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient is provided. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage or food containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient. Methods of treating fatty liver in a subject by administering a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri are also provided.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: September 2, 2014
    Assignee: Megmilk Snow Brand Co., Ltd.
    Inventors: Hiroshi Kawakami, Hiroaki Matsuyama, Masao Sato, Katsumi Imaizumi
  • Publication number: 20140140972
    Abstract: An anti-fatty liver agent containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient is provided. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage or food containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient. Methods of treating fatty liver in a subject by administering a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri are also provided.
    Type: Application
    Filed: January 8, 2014
    Publication date: May 22, 2014
    Applicant: MEGMILK SNOW BRAND Co., Ltd.
    Inventors: Hiroshi KAWAKAMI, Hiroaki MATSUYAMA, Masao SATO, Katsumi IMAIZUMI
  • Patent number: 8647619
    Abstract: It is intended to provide an osteogenesis promoter capable of promoting osteogenesis by promoting the differentiation of osteoblasts, and foods, drinks, drugs or feeds for promoting osteogenesis. Namely, an osteogenesis promoter capable of promoting osteogenesis by promoting the differentiation of osteoblasts which comprises, as the active ingredient, lactoperoxidase and/or a digestion product obtained by digesting lactoperoxidase with a protease such as trypsin; and foods, drinks, drugs or feeds for promoting osteogenesis containing lactoperoxidase and/or its digestion product.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: February 11, 2014
    Assignee: Megmilk Snow Brand Co., Ltd.
    Inventors: Mutsumi Motouri, Hiroaki Matsuyama, Yoshikazu Morita, Atsushi Serizawa, Hiroshi Kawakami
  • Patent number: 8642318
    Abstract: Disclosed is an anti-fatty liver agent comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage/food comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient.
    Type: Grant
    Filed: July 24, 2007
    Date of Patent: February 4, 2014
    Assignee: Megmilk Snow Brand Co., Ltd.
    Inventors: Hiroshi Kawakami, Hiroaki Matsuyama, Masao Sato, Katsumi Imaizumi
  • Patent number: 8580740
    Abstract: A milk protein fraction having following properties (1) to (4) is excellent in bone resorption inhibitory effect, and is useful for preventing or treating bone diseases: (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein having a molecular weight of 12,000 to 16,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 18 to 20 wt % in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.7 to 0.9; and (4) the milk protein fraction has a bone resorption inhibitory effect.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: November 12, 2013
    Assignee: Megmilk Snow Brand Co., Ltd.
    Inventors: Atsushi Serizawa, Yoshikazu Morita, Daisuke Uetsuji, Aiko Ono, Hiroaki Matsuyama, Satoshi Higurashi
  • Patent number: 8547510
    Abstract: A liquid crystal display panel for displaying an image by controlling an orientation direction of a liquid crystal mixture with respect to each pixel, includes a first common electrode which is formed on a first substrate; a second common electrode which is formed on a second substrate and includes a predetermined opening; and a pixel electrode which is formed on the second substrate, wherein the first substrate faces the second substrate so that the liquid crystal mixture with positive dielectric anisotropy is sandwiched between the first common electrode and the second common electrode, and wherein the orientation direction of the liquid crystal mixture changes mainly in a face parallel to the substrate according to an electric field generated from electric potential of the first common electrode, the second common electrode, and the pixel electrode.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: October 1, 2013
    Assignee: NLT Technologies, Ltd.
    Inventors: Hiroaki Matsuyama, Takahiko Watanabe
  • Publication number: 20130225497
    Abstract: A skin collagen production-promoting agent includes a milk protein fraction having following properties (a) to (c) as an active ingredient: (a) being derived from milk, (b) containing proteins having a molecular weight determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of 6000 to 150,000 daltons, and (c) containing 12 to 14 wt % of basic amino acids with respect to the constituent amino acid composition, and having a basic amino acid/acidic amino acid ratio of 0.5 to 0.7.
    Type: Application
    Filed: September 29, 2011
    Publication date: August 29, 2013
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Ken Kato, Aiko Ono, Hiroshi Ueno, Noriko Ueda, Hiroaki Matsuyama
  • Publication number: 20130225501
    Abstract: Skin quality is improved by orally administering a cystatin and/or a degraded product of cystatin in an amount of 10 ?g/day or more per adult, or applying a composition that includes a cystatin and/or a degraded product of cystatin in an amount of 0.001 to 2 wt % based on a total amount of the composition.
    Type: Application
    Filed: September 29, 2011
    Publication date: August 29, 2013
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Ken Kato, Aiko Ono, Hiroshi Ueno, Noriko Ueda, Hiroaki Matsuyama
  • Patent number: 8420599
    Abstract: Disclosed is a bone-reinforcing agent which comprises a milk protein fraction having the following properties (1) to (4): (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein component having a molecular weight of 6,000 to 150,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 12 to 14 wt % in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.5 to 0.7; and (4) the milk protein fraction has an activity of accelerating the calcification in an osteoblast.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: April 16, 2013
    Assignee: MegMilk Snow Brand Co., Ltd.
    Inventors: Atsushi Serizawa, Yoshikazu Morita, Daisuke Uetsuji, Aiko Ono, Hiroaki Matsuyama, Satoshi Higurashi
  • Patent number: 8207131
    Abstract: The present invention relates to a peptide that is derived from a milk protein and has an antioxidative effect, an antioxidant that includes the peptide as an active ingredient, and an antioxidative food, drink, or feed that includes the peptide. The present invention also relates to a peptide that is derived from a milk protein and has an adiponectin production promotion effect, an adiponectin production promoter that includes the peptide as an active ingredient, and an adiponectin production promotion food, drink, or feed that includes the peptide. The present invention further relates to a blood adiponectin level increase promotion and/or decrease inhibition agent that includes a component contained in cheese as an active ingredient, and a blood adiponectin level increase promotion and/or decrease inhibition food or drink that includes a component contained in cheese.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: June 26, 2012
    Assignee: Megmilk Snow Brand Co., Ltd.
    Inventors: Yukiko Kunieda, Satoshi Higurashi, Mutsumi Motouri, Hiroaki Matsuyama, Atsushi Serizawa, Hiroshi Kawakami
  • Publication number: 20120094915
    Abstract: To provide anti-mental fatigue drugs as well as foods, beverages, and fodders that can be taken daily and effective for relieving mental stress and inducing relaxation by intake. An anti-mental fatigue drug containing iron-binding lactoferrin as an active ingredient and foods, beverages, and fodders containing the drug.
    Type: Application
    Filed: April 8, 2010
    Publication date: April 19, 2012
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Ran Emilie Yoshise, Hiroaki Matsuyama, Yukio Kadooka
  • Publication number: 20120077780
    Abstract: The present disclosure relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a fat accumulation inhibitor for a fat cell which includes a milk-derived phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of inhibiting a visceral fat accumulation in a subject, which includes administering the visceral fat accumulation inhibitor which includes a sphingosine-containing phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which includes administering an agent which includes a sphingosine-containing phospholipid as an active ingredient to the blood. The present disclosure also relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a milk-derived phospholipid to a subject.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 29, 2012
    Inventors: Reo Tanaka, Tomoyuki Isogai, Yuko Haruta, Susumu Miura, Ken Kato, Toshimitsu Yoshioka, Hiroshi Kawakami, Satoshi Higurashi, Hiroaki Matsuyama
  • Publication number: 20120009165
    Abstract: Disclosed is an agent for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, or a food, beverage or animal feed for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, which comprises a culture or cell of a lactic acid bacterium belonging to the genus Lactobacillus, particularly Lactobacillus gasseri or Lactobacillus helveticus as an active ingredient. Also disclosed is a visceral fat accumulation inhibitor or a food or beverage for inhibiting the accumulation of a visceral fat, which comprises a culture or cell of Lactobacillus helveticus as an active ingredient.
    Type: Application
    Filed: September 19, 2011
    Publication date: January 12, 2012
    Applicant: MEGMILK SNOW BRAND CO., LTD.
    Inventors: Hiroshi KAWAKAMI, Satoshi HIGURASHI, Hiroaki MATSUYAMA