Patents by Inventor Hiroki Koike

Hiroki Koike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8234941
    Abstract: A specimen analyzing apparatus comprising: a detector for detecting component information regarding a component in a specimen contained in each of analyzing containers, the analyzing containers comprising first and second analyzing containers; an analyzing part for analyzing the component information detected by the detector; a transporting device for transporting specimen containers each containing a specimen, the specimen containers comprising first and second specimen containers; an operation mode selector for selecting one of a first operation mode and a second operation mode; a first supplying device for supplying the specimen of a first amount; a second supplying device for supplying the specimen of a second amount grater than the first amount; and a supply controller for controlling the first and second supplying devices in accordance with an operation mode selected by the operation mode selector, is disclosed. A specimen analyzing method is also disclosed.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: August 7, 2012
    Assignee: Sysmex Corporation
    Inventors: Kazuya Fukuda, Hiroki Koike, Hironori Katsumi, Takashi Yamato, Masayuki Ikeda, Tsuyoshi Fukuzaki, Daisuke Nakano, Masanori Imazu, Nobuhiro Kitagawa
  • Patent number: 8169813
    Abstract: A method for evaluating an SRAM memory cell in which the time required for designing the SRAM memory cell can be shortened by evaluating static noise margin in a shortened time. A recording medium which records an evaluation program is also provided. The coordinate conversion which rotates the coordinate axis by 45 degrees is applied to the input/output characteristic data of a first inverter of the SRAM memory cell, and the first proximity curve function is specified by fitting the input/output characteristic data of the first inverter to the proximity curve. The coordinate conversion which rotates the coordinate axis by 45 degrees is applied to the input/output characteristic data of a second inverter of the SRAM memory cell, and the second proximity curve function is specified by fitting the input/output characteristic data of the second inverter to the proximity curve.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: May 1, 2012
    Assignee: Kyushu Institute of Technology
    Inventors: Kazuyuki Nakamura, Hiroki Koike
  • Publication number: 20120057667
    Abstract: [Solving Means] A resonance calculation program is configured to calculate an effective cross section including Step S4 of setting a calculation point in the gray range in the resonance region; Step S5 of calculating a neutron flux set at the calculation point and corresponding to a macroscopic cross section based on Method of Characteristics; Step S6 of fitting a fitting equation to the calculated macroscopic cross section and the calculated neutron flux, and calculating first and second rational coefficients; Step S7 of calculating a background cross section based on the first rational coefficient; Step S8 of interpolating the effective cross section, with the background cross section used as an argument; Step S9 of calculating the neutron flux based on the background cross section; and Step S10 of calculating the effective cross section based on the effective cross section, the neutron flux, and the second rational coefficient obtained at the coefficient calculation step.
    Type: Application
    Filed: December 22, 2010
    Publication date: March 8, 2012
    Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventors: Hiroki Koike, Kazuya Yamaji, Daisuke Sato, Shinobu Tsubota, Hideki Matsumoto
  • Patent number: 8084476
    Abstract: This invention provides a compound of the formula (I): wherein X represents a carbon atom or the like: Y represents imino, or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 independently represents a hydrogen atom or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: December 27, 2011
    Assignee: Raqualia Pharma Inc.
    Inventors: Hiroki Koike, Kana Kon-i, Yukari Matsumoto, Kazunari Nakao, Yoshiyuki Okumura, Tatsuya Yamagishi
  • Patent number: 7955556
    Abstract: An analyzer capable of operating in a normal processing mode performing sequential analysis of a plurality of specimens and in an interrupting mode performing analysis of an urgent specimen that comprising a suction unit for suctioning an urgent specimen, an analysis unit for analyzing an urgent specimen suctioned by the suction unit, an urgent specimen container holder for holding an urgent specimen container containing an urgent specimen, and a moving mechanism for moving the urgent specimen container holder between a placement position at which an urgent specimen container is placed in the holder, and a suction position at which an urgent specimen is suctioned from an urgent specimen container, wherein the moving mechanism comprises a movement force supplying mechanism for supplying a force to move the urgent specimen container holder from the suction position to the placement position is disclosed.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: June 7, 2011
    Assignee: Sysmex Corporation
    Inventors: Hiroki Koike, Masayuki Ikeda
  • Publication number: 20110123397
    Abstract: A sample processing apparatus, including: a sample processing unit for obtaining a sample from a sample container positioned at a sample obtaining position and performing a predetermined process of the sample; a transport unit for transporting a sample rack holding the sample container via the sample obtaining position; and a transport controller for performing a stop process to stop the transport operation of the sample rack by the transport unit when a transport suspension event has occurred during the transport operation of the sample rack, and for controlling the transport unit to restart the transport operation of the sample rack from a stop position at which the sample rack has been stopped by the stop process.
    Type: Application
    Filed: September 16, 2010
    Publication date: May 26, 2011
    Applicant: SYSMEX CORPORATION
    Inventors: Takashi YAMATO, Hiroshi Kurono, Hiroki Koike
  • Patent number: 7931862
    Abstract: A sample rack transport apparatus for transporting a sample rack holding a container containing a sample is provided with a rack transport mechanism for transporting sample racks, and a control unit for controlling the operation of the transport mechanism. The transport mechanism has actuators, and the samples rack is transported by the operation of these actuators. The control unit is accommodated in a control box. The transport mechanism and control box are supported in a case. The control box is provided below the transport mechanism, and is configured so as to be slidably transferred into and from the case.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: April 26, 2011
    Assignee: Sysmex Corporation
    Inventors: Akio Toyoda, Hiroki Koike, Yoichi Nakamura
  • Publication number: 20100290952
    Abstract: The present invention is to present a sample analyzer, including: a lamp member which includes a halogen lamp including an electrode and a filament connected to the electrode; a holding mechanism for holding the lamp member such that the filament of the halogen lamp is positioned above the electrode; a light receiver for receiving light irradiated from the halogen lamp through an analysis sample; and an analysis unit for analyzing a component contained in the analysis sample based on the light received by the light receiver.
    Type: Application
    Filed: May 6, 2010
    Publication date: November 18, 2010
    Applicant: SYSMEX CORPORATION
    Inventors: Hiroki Koike, Norimasa Yamamoto
  • Publication number: 20100166606
    Abstract: A transporting apparatus for transporting a sample rack capable of holding a plurality of sample containers comprising: a transporting path that has a width allowing placing of each of a first sample rack and a second sample rack having a length in longitudinal direction greater than that of the first sample rack, the transporting path extending in a transporting direction intersecting the longitudinal direction of the first sample rack or the second sample rack placed on the transporting path; and a transport mechanism configured for transporting each of the first sample rack and the second sample rack placed on the transporting path in the transporting direction, is disclosed. A sample analyzer is also disclosed.
    Type: Application
    Filed: December 24, 2009
    Publication date: July 1, 2010
    Applicant: Sysmex Corporation
    Inventors: Hiroki KOIKE, Akio TOYODA
  • Patent number: 7723321
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5, R6, R7 and R8 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: May 25, 2010
    Assignee: RaQualia Pharma Inc.
    Inventors: Takeshi Hanazawa, Hiroki Koike
  • Publication number: 20100124518
    Abstract: A transporting apparatus for transporting a specimen rack holding a specimen container containing a specimen, comprising: an engage unit capable of engaging with the specimen rack; and a moving mechanism for moving the engage unit in a transport direction of the specimen rack, the transport direction including a first direction and a second direction opposite to the first direction, wherein the engage unit comprises: a pair of engage members, capable of mutually approaching and separating relative to the transport direction, and engaging with the specimen rack gaplessly relative to the transport direction by the approaching operation or the separating operation; and a driver for driving the pair of engage members so as to perform the approaching operation and the separating operation. A specimen analyzing apparatus is also disclosed.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 20, 2010
    Applicant: SYSMEX CORPORATION
    Inventor: Hiroki KOIKE
  • Patent number: 7718809
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5 and R6, R7, R8 and R9 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: May 18, 2010
    Assignee: RaQualia Pharma Inc.
    Inventors: Hiroki Koike, Sachiko Sakakibara
  • Publication number: 20100107744
    Abstract: A specimen analyzing apparatus comprising: a detector for detecting component information regarding a component in a specimen contained in each of analyzing containers, the analyzing containers comprising first and second analyzing containers; an analyzing part for analyzing the component information detected by the detector; a transporting device for transporting specimen containers each containing a specimen, the specimen containers comprising first and second specimen containers; an operation mode selector for selecting one of a first operation mode and a second operation mode; a first supplying device for supplying the specimen of a first amount; a second supplying device for supplying the specimen of a second amount grater than the first amount; and a supply controller for controlling the first and second supplying devices in accordance with an operation mode selected by the operation mode selector, is disclosed. A specimen analyzing method is also disclosed.
    Type: Application
    Filed: October 28, 2009
    Publication date: May 6, 2010
    Applicant: SYSMEX CORPORATION
    Inventors: Kazuya FUKUDA, Hiroki Koike, Hironori Katsumi, Takashi Yamato, Masayuki Ikeda, Tsuyoshi Fukuzaki, Daisuke Nakano, Masanori Imazu, Nobuhiro Kitagawa
  • Publication number: 20100048532
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, A and E are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the method of treatment and the use, comprising such compounds for the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), laryngopharyngeal reflux disease, peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zolli?ger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, cancer, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    Type: Application
    Filed: September 17, 2007
    Publication date: February 25, 2010
    Applicant: RaQualia Pharma Inc.
    Inventors: Hiroki Koike, Mikio Morita
  • Publication number: 20090163558
    Abstract: This invention provides a compound of the formula (I): wherein X represents a carbon atom or the like: Y represents imino, or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 independently represents a hydrogen atom or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.
    Type: Application
    Filed: February 10, 2009
    Publication date: June 25, 2009
    Applicant: RaQualia Pharma Inc.
    Inventors: Hiroki Koike, Kana Kon-i, Yukari Matsumoto, Kazunari Nakao, Yoshiyuki Okumura, Tatsuya Yamagishi
  • Patent number: 7534914
    Abstract: This invention provides a compound of the formula (I): wherein X represents a carbon atom or the like: Y represents imino, or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 independently represents a hydrogen atom or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.
    Type: Grant
    Filed: April 29, 2005
    Date of Patent: May 19, 2009
    Assignee: ReQualia Pharma Inc.
    Inventors: Hiroki Koike, Kana Kon-i, Yukari Matsumoto, Kazunari Nakao, Yoshiyuki Okumura, Tatsuya Yamagishi
  • Patent number: 7448487
    Abstract: A transporting apparatus is described, a representative one of which includes a transporting apparatus which transports at least one specimen container accommodated in a rack to a specimen supplying position for supplying a specimen processing apparatus, comprising: a transport mechanism configured to transport the at least one specimen container to the specimen supplying position by transporting the rack; and a detection unit for obtaining information specifying the position of the rack being transported by the transport mechanism.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: November 11, 2008
    Assignee: Sysmex Corporation
    Inventor: Hiroki Koike
  • Publication number: 20080214519
    Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5 and R6, R7, R8 and R9 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    Type: Application
    Filed: June 2, 2006
    Publication date: September 4, 2008
    Inventors: Hiroki Koike, Sachiko Sakakibara
  • Publication number: 20080207665
    Abstract: This invention provides the compounds of formula (I): or a pharmaceutically acceptable ester or salt thereof, wherein R1 and R2 independently represent hydrogen or the like; R3 represents aryl or the like; —X—Y— represents —CH2O— or the like, and n represents 0, 1 or 2. These compounds have ORL1-receptor antagonist activity; and therefore, are useful to treat diseases or conditions such as pain, various CNS diseases etc.
    Type: Application
    Filed: June 8, 2006
    Publication date: August 28, 2008
    Inventors: Yoshinobu Hashizume, Masako Hirota, Sachiko Mihara, Hiroshi Nakamura, Hiroki Koike, Yukari Matsumoto
  • Publication number: 20080200490
    Abstract: This invention provides the compounds of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 and R2 independently represent hydrogen or the like; R3 and R4 independently represents hydrogen or the like; R5 represents aryl or the like; —X—Y— represents —CH2O— or the like; and n represents 0, 1 or 2. These compounds have ORL1-receptor antagonist activity; and therefore, are useful to treat diseases or conditions such as pain, various CNS diseases etc.
    Type: Application
    Filed: June 9, 2006
    Publication date: August 21, 2008
    Inventors: Yoshinobu Hashizume, Masako Hirota, Sachiko Mihara, Hiroshi Nakamura, Hiroki Koike, Yukari Matsumoto