Patents by Inventor Hiroki Sasaki
Hiroki Sasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230195019Abstract: An image forming apparatus includes a stacking portion including a lifting portion, a feeding member feeding a sheet stacked on the lifting portion to a conveyance passage, a position detector detecting movement of the sheet stacked on to a feedable position to the conveyance passage, a driver including a motor and performing the lifting operation of the lifting portion, a rotation detector detecting rotation of the motor, and a controller. The controller determines a factor that the position detector does not detect the movement of the sheet stacked on the lifting portion to the feedable position within a predetermined time based on a detection result of the rotation detector while controlling the driver to lift up the lifting portion.Type: ApplicationFiled: December 13, 2022Publication date: June 22, 2023Inventors: HIROKI SASAKI, YOSHITERU KAIDA
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Publication number: 20230106422Abstract: A solid-state imaging element includes a pixel and an image processing unit. The pixel has a common transistor, a charge accumulation unit, and a power supply. The common transistor has a first terminal and a second terminal. The common transistor maintains a voltage of the first terminal at a predetermined voltage with a voltage applied from the power supply and outputs a voltage corresponding to a change in a voltage of the charge accumulation unit from the second terminal, based on a condition that an element voltage is a ground voltage. The common transistor outputs a voltage corresponding to a change in a voltage of the charge accumulation unit from the first terminal, based on the element voltage is higher than the ground voltage. The image processing unit generates a luminance image according to a change in the voltage output from the second terminal of the common transistor.Type: ApplicationFiled: September 28, 2022Publication date: April 6, 2023Inventor: HIROKI SASAKI
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Publication number: 20220087987Abstract: The present invention provides a method for treating SWI/SNF complex-deficient cancers comprising a glutathione (GSH) metabolic pathway inhibitor, a pharmaceutical composition comprising a glutathione (GSH) metabolic pathway inhibitor for therapy in SWI/SNF complex-deficient cancers, and a glutathione (GSH) metabolic pathway inhibitor for use in treating SWI/SNF complex-deficient cancers. The present invention also provides a method for detecting and/or selecting a susceptible patient to a glutathione (GSH) metabolic pathway inhibitor.Type: ApplicationFiled: December 16, 2019Publication date: March 24, 2022Applicants: National Cancer Center, ONO PHARMACEUTICAL CO., LTD.Inventors: Hideaki OGIWARA, Takashi KOHNO, Hiroki SASAKI
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Publication number: 20210399034Abstract: A camera module is configured to capture an optical image of a target area and includes a lens member, an imager, a light transmitting member, and a seat. The lens member is configured to receive light from the target area. The imager has a curved portion convex in a direction away from the lens member and is configured to capture the optical image formed on the curved portion. The light transmitting member optically couples the lens member and the imager. The seat has a supporting portion that supports an outer rim of the imager and a fluid space defined inside the supporting portion. A heat dissipation fluid undergoes convection in the fluid space. The curved portion is interposed between the light transmitting member and the seat having the supporting portion and the fluid space.Type: ApplicationFiled: June 16, 2021Publication date: December 23, 2021Inventors: Kouji SATOU, Hiroki SASAKI, Shotaro MIYAWAKI, Akira WADA, Satoru WAKIYAMA, Kazuhiro AOYAMA
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Publication number: 20210292853Abstract: The purpose is to reveal a polynucleotide that is a novel causal gene of pancreatic cancer and thereby provide a method for detecting the polynucleotide or a polypeptide encoded thereby to select a subject positive for the polynucleotide or polypeptide and a method expected to be useful for to identify patients suitable for therapies and a primer set therefor and a kit for detection. In the method, a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP6 gene or a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP26 gene, or a fusion protein encoded thereby is detected. The primer set comprises a sense primer designed for a part encoding CLDN18 and an antisense primer designed for a part encoding ARHGAP6 or a part encoding ARHGAP26.Type: ApplicationFiled: June 2, 2021Publication date: September 23, 2021Applicants: Astellas Pharma Inc., National Cancer CenterInventor: Hiroki SASAKI
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Patent number: 11053553Abstract: The purpose is to reveal a polynucleotide that is a novel causal gene of pancreatic cancer and thereby provide a method for detecting the polynucleotide or a polypeptide encoded thereby to select a subject positive for the polynucleotide or polypeptide and a method expected to be useful for to identify patients suitable for therapies and a primer set therefor and a kit for detection. In the method, a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP6 gene or a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP26 gene, or a fusion protein encoded thereby is detected. The primer set comprises a sense primer designed for a part encoding CLDN18 and an antisense primer designed for a part encoding ARHGAP6 or a part encoding ARHGAP26.Type: GrantFiled: August 9, 2017Date of Patent: July 6, 2021Assignees: Astellas Pharma Inc., National Cancer CenterInventor: Hiroki Sasaki
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Patent number: 10969390Abstract: A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c): (a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject; (b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and (c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).Type: GrantFiled: September 24, 2015Date of Patent: April 6, 2021Assignees: NATIONAL CANCER CENTER, KYOTO UNIVERSITY, OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiroki Sasaki, Kazuhiko Aoyagi, Manabu Muto, Hiroo Takahashi
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Patent number: 10903228Abstract: A semiconductor storage device includes a semiconductor substrate and a plurality of first wiring layers stacked above the semiconductor substrate in a first direction orthogonal to the semiconductor substrate, and extending in a second direction intersecting the first direction and parallel to the semiconductor substrate. The device further includes a first memory pillar including a semiconductor layer and a first insulation layer extending in the first direction, the first insulation layer provided between the plurality of first wiring layers and the semiconductor layer so as to contact the semiconductor layer, and charge storage layers provided respectively between the plurality of first wiring layers and the first insulation layer. One or more of the charge storage layers is in contact with the first insulation layer. A plurality of second insulation layers is provided between each of the plurality of first wiring layers and each of the charge storage layers.Type: GrantFiled: August 27, 2018Date of Patent: January 26, 2021Assignee: TOSHIBA MEMORY CORPORATIONInventors: Hiroki Sasaki, Atsushi Murakoshi, Ryuji Ohba
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Publication number: 20200385779Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an OCLN gene and a part of an ARHGAP26 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding OCLN and an antisense primer designed from a section encoding ARHGAP26.Type: ApplicationFiled: March 13, 2020Publication date: December 10, 2020Inventors: Hiroki Sasaki, Hitoshi Ichikawa, Makoto Asaumi, Kazuhisa Tsunoyama
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Patent number: 10818688Abstract: A storage device includes: a plurality of electrode films stacked in a first direction, and extending in a second direction intersecting the first direction; a first semiconductor film provided adjacent to the plurality of electrode films, and extending in the first direction; a first charge holding film provided between one electrode film among the plurality of electrode films, and the semiconductor film, and including any one of a metal, a metal compound, and a high dielectric material; and a second semiconductor film located between the first semiconductor film and the charge holding film, and extending in the first direction along the first semiconductor film. The second semiconductor film is electrically insulated from the plurality of electrode films, the first charge holding film, and the first semiconductor film.Type: GrantFiled: September 6, 2018Date of Patent: October 27, 2020Assignee: TOSHIBA MEMORY CORPORATIONInventors: Atsushi Murakoshi, Hiroki Sasaki
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Publication number: 20200299782Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an RP2 gene and a part of an ARHGAP6 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding RP2 and an antisense primer designed from a section encoding ARHGAP6.Type: ApplicationFiled: March 13, 2020Publication date: September 24, 2020Inventors: Hiroki Sasaki, Hitoshi Ichikawa
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Patent number: 10619216Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an RP2 gene and a part of an ARHGAP6 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding RP2 and an antisense primer designed from a section encoding ARHGAP6.Type: GrantFiled: August 23, 2016Date of Patent: April 14, 2020Assignees: Astellas Pharma Inc., National Cancer CenterInventors: Hiroki Sasaki, Hitoshi Ichikawa
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Patent number: 10619184Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an OCLN gene and a part of an ARHGAP26 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding OCLN and an antisense primer designed from a section encoding ARHGAP26.Type: GrantFiled: August 23, 2016Date of Patent: April 14, 2020Assignees: Astellas Pharma Inc., National Cancer CenterInventors: Hiroki Sasaki, Hitoshi Ichikawa, Makoto Asaumi, Kazuhisa Tsunoyama
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Publication number: 20190273092Abstract: A semiconductor storage device includes a semiconductor substrate and a plurality of first wiring layers stacked above the semiconductor substrate in a first direction orthogonal to the semiconductor substrate, and extending in a second direction intersecting the first direction and parallel to the semiconductor substrate. The device further includes a first memory pillar including a semiconductor layer and a first insulation layer extending in the first direction, the first insulation layer provided between the plurality of first wiring layers and the semiconductor layer so as to contact the semiconductor layer, and charge storage layers provided respectively between the plurality of first wiring layers and the first insulation layer. One or more of the charge storage layers is in contact with the first insulation layer. A plurality of second insulation layers is provided between each of the plurality of first wiring layers and each of the charge storage layers.Type: ApplicationFiled: August 27, 2018Publication date: September 5, 2019Applicant: TOSHIBA MEMORY CORPORATIONInventors: Hiroki SASAKI, Atsushi MURAKOSHI, Ryuji OHBA
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Publication number: 20190259774Abstract: A storage device includes: a plurality of electrode films stacked in a first direction, and extending in a second direction intersecting the first direction; a first semiconductor film provided adjacent to the plurality of electrode films, and extending in the first direction; a first charge holding film provided between one electrode film among the plurality of electrode films, and the semiconductor film, and including any one of a metal, a metal compound, and a high dielectric material; and a second semiconductor film located between the first semiconductor film and the charge holding film, and extending in the first direction along the first semiconductor film. The second semiconductor film is electrically insulated from the plurality of electrode films, the first charge holding film, and the first semiconductor film.Type: ApplicationFiled: September 6, 2018Publication date: August 22, 2019Applicant: TOSHIBA MEMORY CORPORATIONInventors: Atsushi MURAKOSHI, Hiroki SASAKI
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Publication number: 20190218620Abstract: The purpose is to reveal a polynucleotide that is a novel causal gene of pancreatic cancer and thereby provide a method for detecting the polynucleotide or a polypeptide encoded thereby to select a subject positive for the polynucleotide or polypeptide and a method expected to be useful for to identify patients suitable for therapies and a primer set therefor and a kit for detection. In the method, a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP6 gene or a polynucleotide comprising a fusion point of a part of a CLDN18 gene and an ARHGAP26 gene, or a fusion protein encoded thereby is detected. The primer set comprises a sense primer designed for a part encoding CLDN18 and an antisense primer designed for a part encoding ARHGAP6 or a part encoding ARHGAP26.Type: ApplicationFiled: August 9, 2017Publication date: July 18, 2019Applicants: Astellas Pharma Inc., National Cancer CenterInventor: Hiroki SASAKI
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Patent number: 10113907Abstract: Provided are an ultraviolet-sensing sheet, an ultraviolet-sensing set, and an ultraviolet-sensing method, in which color gradation properties which are suitable for detecting an ultraviolet dose are obtained and in which the coloring of an ultraviolet-sensing layer caused by the effect of light other than ultraviolet light is prevented. An ultraviolet-sensing sheet 1 includes: a filter layer 10 that selectively allows transmission of light having a specific wavelength; and an ultraviolet-sensing layer 20 that includes a capsule including a color-forming dye and a photooxidant. It is preferable that the filter layer 10 has a maximum value of the transmittance in a wavelength range of 300 nm or longer and shorter than 380 nm.Type: GrantFiled: January 23, 2017Date of Patent: October 30, 2018Assignee: FUJIFILM CorporationInventors: Masahiro Hatta, Takayuki Matsumoto, Hiroki Sasaki
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Publication number: 20180251850Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an RP2 gene and a part of an ARHGAP6 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding RP2 and an antisense primer designed from a section encoding ARHGAP6.Type: ApplicationFiled: August 23, 2016Publication date: September 6, 2018Inventors: Hiroki Sasaki, Hitoshi Ichikawa
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Publication number: 20180237862Abstract: The object of the invention is to elucidate a new causative gene of cancer, polynucleotide, and thereby provide a method for detecting the polynucleotide or a polypeptide that is encoded by the polynucleotide, as well as a primer set or a detection kit for such detection. The detection method detects a fusion gene of a part of an OCLN gene and a part of an ARHGAP26 gene, or a fusion protein encoded by such gene. The primer set includes a sense primer designed from a section encoding OCLN and an antisense primer designed from a section encoding ARHGAP26.Type: ApplicationFiled: August 23, 2016Publication date: August 23, 2018Inventors: Hiroki Sasaki, Hitoshi Ichikawa, Makoto Asaumi, Kazuhisa Tsunoyama
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Publication number: 20180208787Abstract: Provided are an aqueous pigment dispersion that includes an azo pigment represented by Formula (1) as described in the specification, and/or a tautomer thereof, the azo pigment showing characteristic X-ray diffraction peaks at least at Bragg's angles (2?±0.2°) of 4.8°, 7.2°, 9.7°, 20.0°, 17.3°, 26.0°, and 26.7° in CuK? characteristic X-ray diffraction; a first dispersant; a second dispersant; and water, the aqueous pigment dispersion being obtained via the following Step b. Step b: a step of dispersing an azo pigment represented by Formula (1) and/or a tautomer thereof, a first dispersant, and a second dispersant in water and thereby obtaining an aqueous pigment dispersion.Type: ApplicationFiled: March 22, 2018Publication date: July 26, 2018Applicant: FUJIFILM CorporationInventors: Keiichi TATEISHI, Hiroki SASAKI, Yoshiaki NAGATA