Abstract: The present invention aims to provide an agent for the prophylaxis or treatment of diabetes, which has a superior hypoglycemic action, and is associated with a fewer side effects such as body weight gain and the like. The present invention relates to an agent for the prophylaxis or treatment of diabetes comprising a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof, or a prodrug thereof.

Abstract: A compound represented by the formula wherein R1, R2, R3 and R6 are the same or different and each is a hydrogen atom or a substituent; one of R4 and R5 is a hydrogen atom and the other is a group represented by the formula: —C(?X)—R7 wherein X is N—O—R8 or N—NH—R9 wherein R8 and R9 are the same or different and each is a hydrogen atom or a group bonded via a carbon atom; and R7 is a hydrogen atom or a substituent, and the like and a salt thereof have a superior I?B kinase inhibitory activity, and useful as pharmaceutical agents such as agents for preventing or treating diabetes and the like.

Abstract: A separator having at least: a base material layer made of a microporous membrane of a polyolefin resin; and a functional resin layer which is made of a resin different from the polyolefin resin and has a porous interconnected structure in which many holes are mutually interconnected. A diameter of a narrowest portion of through-holes of said functional resin layer is larger than a diameter of a narrowest portion of through-holes of said base material layer.

Abstract: A nonaqueous electrolyte battery includes a cathode that is placed opposite an anode via a separator, an open circuit voltage in the full charge state is within a range of 4.25 to 6.00 V per a pair of the cathode and the anode, the separator includes a base material layer which includes a polyolefin resin material and a surface layer which is provided at least on the surface at the side of the cathode of the base material layer and includes at least one selected from the group including polyvinylidene fluoride, polytetrafluoroethylene, and polypropylene, and at least one selected from the group including aramid, polyimide, and ceramics is present on the outermost surface of the surface layer.

Abstract: A substance includes an oxide including at least one element selected from the group including cobalt Co, nickel Ni, manganese Mn, iron Fe, and copper Cu; and silicon Si chemically bonded to the surface of the oxide. Also, a battery includes a cathode, an anode, and an electrolyte, wherein the cathode includes an oxide including at least one selected from the group including cobalt Co, nickel Ni, manganese Mn, iron Fe, and copper Cu; and a substance including silicon Si chemically bonded to the surface of the oxide.

Abstract: The present invention provides a compound represented by the formula: wherein each symbol is as defined in the specification. Since the compound of the present invention has superior hypoglycemic action and superior hypolipidemic action, it is useful as an agent for the prophylaxis or treatment of diabetes, hyperlipidemia, impaired glucose tolerance and the like.

Abstract: A non-aqueous electrolyte secondary battery is provided and includes a battery element in which a positive electrode having a positive electrode active material layer provided on a positive electrode collector and a negative electrode having a negative electrode active material layer provided on a negative electrode collector are stacked via a separator, and an edge of the negative electrode is disposed so as to protrude along the planar direction relative to an edge of the positive electrode. A positive electrode terminal is connected to the positive electrode, and a negative electrode terminal is connected to the negative electrode. The negative electrode terminal has a contact piece intersecting with the continuous direction of the edge of the negative electrode and intersecting with the planar direction of the negative electrode. The contact piece comprehensively cleaves and contacts a plurality of the edges of the negative electrode.

Abstract: A separator which includes a covering layer in which a fine framework of polyolefin resin is coated with a glass layer and an exposed layer in which the polyolefin resin is exposed is provided. A battery is provided having a cathode and an anode, an electrolyte, and a separator where the separator has the covering layer in which the fine framework of polyolefin resin is coated with the glass layer and a method for manufacturing a separator including the step of coating a fine framework of polyolefin resin with the glass layer by applying a precursor containing viscous liquid product which contains only polysilazane compound or a mixture of viscous liquid product which contains only polysilazane compound with polycarbosilazane compound to the polyolefin resin and placing the precursor applied polyoleline resin in a water bath to dry.

Abstract: The present invention provides an agent for the prophylaxis or treatment of diabetes, which has a superior hypoglycemic action, and is associated with a fewer side effects such as body weight gain and the like. The present invention relates an agent for the prophylaxis or treatment of diabetes, which comprises a compound represented by wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof.

Abstract: A compound represented by the formula wherein R1, R2, R3 and R6 are the same or different and each is a hydrogen atom or a substituent; one of R4 and R5 is a hydrogen atom and the other is a group represented by the formula: —C(?X)—R7 wherein X is N—O—R8 or N—NH—R9 wherein R8 and R9 are the same or different and each is a hydrogen atom or a group bonded via a carbon atom; and R7 is a hydrogen atom or a substituent, and the like and a salt thereof have a superior I?B kinase inhibitory activity, and useful as pharmaceutical agents such as agents for preventing or treating diabetes and the like.

Abstract: The invention provides a battery achieving excellent battery characteristics by using, as an anode active material, any of metal elements and metalloid elements each of which can form an alloy with a lithium, alloys of these elements, and compounds of these elements. Mesh projections as a frame structure are formed on the surface on the side facing an anode active material layer, of an anode collector. By the mesh projections, expansion and contraction in the plane direction of the anode active material layer is suppressed. Thus, pulverization, peeling, and the like of the anode active material layer caused by expansion and contraction thereof are prevented and the cycle characteristics are improved.

Abstract: There is provided a lithium/iron disulfide primary cell which includes a positive electrode using iron disulfide as a positive active material, a negative electrode using lithium as a negative active material, and an organic electrolytic solution, in which the organic electrolytic solution contains a transition metal cation.

Abstract: The present invention relates to a compound represented by the formula wherein R1 is an optionally substituted 5-membered heterocyclic group; X is a bond etc.; Q is a divalent hydrocarbon group having 1 to 20 carbon atoms; Y is a bond etc.; ring A is an aromatic ring optionally further having 1 to 3 substituents; Z is —(CH2)n—Z1— (n is an integer of 0 to 8 and Z1 is a bond etc.) and the like; ring B is a 5-membered heterocycle optionally further having 1 to 3 substituents; W is a divalent saturated hydrocarbon group having 1 to 20 carbon atoms; R2 is —OH etc., or a salt thereof. A pharmaceutical composition containing this compound is useful as a prophylactic or therapeutic agent of diseases such as diabetes mellitus and the like.

Abstract: To provide a novel oxyiminoalkanoic acid derivative which has excellent hypoglycemic and hypolipidemic actions and which is used for the prevention or treatment of diabetes mellitus, hyperlipemia, insulin insensitivity, insulin resistance and impaired glucose tolerance.

Abstract: An anode material capable of improving cycle characteristics, and a battery using the anode material are provided. A disk-shaped cathode contained in a package can and a disk-shaped anode contained in a package cup are laminated with a separator in between. The anode includes an alloy or a compound including iron in addition to at least either tin or silicon. The ratio of iron in the alloy or the compound is preferably about 15% by mass or less. Moreover, it is preferable that the alloy or the compound further includes chromium in an amount of less than 1500 ppm by mass.

Abstract: Crystals of (E)-4-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyloxyimino]-4-phenylbutyric acid (provided that crystals having a melting point of 126° C. to 127° C. are excluded), which have an excellent anti-diabetic action.

Abstract: A nonaqueous electrolyte battery has a spirally coiled electrode body (10) including a cathode (11) having a cathode active material and an anode (12) having an anode active material which are coiled through a separator (13) in a battery can (1). As the separator (13), is used a separator having a plurality of laminated microporous films made of polyolefine which have different film layer thickness and average pore size. Specially, the separator (13) has three or more layers of microporous films made of polyolefine laminated. Further, the outermost layer of the separator is made of porous polypropylene and at least one layer of inner layers is made of porous polyethylene. The total of the thickness of layers made of porous polyethylene is located within a range of 40% to 84% as thick as the thickness of the separator. Thus, the temperature of a battery can be controlled, a reliability is enhanced and a productivity and cyclic characteristics are improved.

Abstract: The present invention relates to a compound represented by the formula 1

Abstract: A method of manufacturing a negative material and a secondary battery in which a belt-shaped positive electrode and a belt-shaped negative electrode are wound together with a separator in between them to form a wound electrode body. The wound electrode battery is then inserted inside a battery can. Preferably, the negative electrode is produced with crushed silicon or a silicon compound in an oxygen partial pressure atmosphere within a value from higher than 10 Pa to lower than an oxygen partial pressure of air.

Abstract: The invention provides a battery achieving excellent battery characteristics by using, as an anode active material, any of metal elements and metalloid elements each of which can form an alloy with a lithium, alloys of these elements, and compounds of these elements. Mesh projections as a frame structure are formed on the surface on the side facing an anode active material layer, of an anode collector. By the mesh projections, expansion and contraction in the plane direction of the anode active material layer is suppressed. Thus, pulverization, peeling, and the like of the anode active material layer caused by expansion and contraction thereof are prevented and the cycle characteristics are improved.