Patents by Inventor Hiroshi Kawabata

Hiroshi Kawabata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10029731
    Abstract: A work vehicle includes a prime mover unit disposed in a front part of the vehicle body, a driving part located in a rear part of the vehicle body, a battery disposed between the prime mover unit and the driving part, a base frame disposed in a lower part of the vehicle body and a center pillar that extends upward from the base frame. The prime mover unit includes a radiator disposed immediately forward of the center pillar.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: July 24, 2018
    Assignee: Kubota Corporation
    Inventors: Koichiro Matsumoto, Shoichiro Nagaishi, Ryo Matsumoto, Hiroshi Kawabata, Hiroki Nagai, Masahiro Izumi, Masaki Takaoka, Tasuku Teraoka, Takashi Kumashiro
  • Patent number: 9969988
    Abstract: The present invention provides a pipecolic acid 4-hydroxylase protein exemplified by the following (A), (B), and (C), having activity to react with L-pipecolic acid in the presence of 2-oxoglutaric acid and iron(II) ions to produce trans-4-hydroxy-L-pipecolic acid, and a method for producing 4-hydroxy amino acid, which method comprises reacting the pipecolic acid 4-hydroxylase protein, cells containing the protein, a treated product of the cells, and/or a culture liquid obtained by culturing the cells, with ?-amino acid to produce 4-hydroxy amino acid: (A) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18; (B) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18 except that one or several amino acids are deleted, substituted, and/or added, and having pipecolic acid 4-hydroxylase activity; and (C) a polypeptide having an amino acid sequence that is not less than 80% identical to the amino acid sequence rep
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: May 15, 2018
    Assignee: API CORPORATION
    Inventors: Makoto Hibi, Jun Ogawa, Ryoma Miyake, Hiroshi Kawabata
  • Publication number: 20180086912
    Abstract: A monomer composition containing an unsaturated polyalkylene glycol ether-based monomer is provided having excellent stability. The monomer composition contains an unsaturated polyalkylene glycol ether-based monomer represented by the following chemical formula (1): YO(R1O)nR2 ??(1) [in the formula, Y represents an alkenyl group having 2 to 7 carbon atoms; R1O represents one or two or more types of oxyalkylene groups having 2 to 18 carbon atoms; n represents an average addition, mole number of oxyalkylene groups and is a number of 5 to 500; and R2 represents a hydrogen atom, or a hydrocarbon group having 1 to 30 carbon atoms], an organic acid, and water, and having a pH of 4 to 13.
    Type: Application
    Filed: November 10, 2017
    Publication date: March 29, 2018
    Inventor: Hiroshi KAWABATA
  • Patent number: 9914487
    Abstract: A work vehicle includes: a vehicle body frame; a prime mover part that is supported by the vehicle body frame; a bonnet that is configured to vertically swing between a closed position at which the prime mover part is covered, and an open position at which the prime mover part is open; and a support frame that supports a free end side of the bonnet located at the closed position. At least left and right guide-target parts of the bonnet or left and right guiding parts of the support frame have left and right inclined surfaces that serve as centering effective surfaces.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: March 13, 2018
    Assignee: Kubota Corporation
    Inventors: Koichiro Matsumoto, Nobuyuki Yamashita, Hiroshi Kawabata, Tomohisa Yamamoto, Masayuki Akita, Tasuku Teraoka, Yoshihisa Tonoya
  • Patent number: 9850378
    Abstract: A monomer composition containing an unsaturated polyalkylene glycol ether-based monomer is provided having excellent stability. The monomer composition contains an unsaturated polyalkylene glycol ether-based monomer represented by the following chemical formula (1): YO(R1O)nR2??(1) [in the formula, Y represents an alkenyl group having 2 to 7 carbon atoms; R1O represents one or two or more types of oxyalkylene groups having 2 to 18 carbon atoms; n represents an average addition mole number of oxyalkylene groups and is a number of 5 to 500; and R2 represents a hydrogen atom or a hydrocarbon group having 1 to 30 carbon atoms], an organic acid, and water, and having a pH of 4 to 13.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: December 26, 2017
    Assignee: Nippon Shokubai Co., Ltd.
    Inventor: Hiroshi Kawabata
  • Publication number: 20170305867
    Abstract: An object of the present invention is to provide a novel method capable of producing rosuvastatin calcium and intermediates therefor efficiently, inexpensively and with high purity. The present invention provides a method of efficiently producing rosuvastatin calcium and intermediates therefor having a high purity at an industrial scale, without using an extremely low temperature reaction or a special asymmetric catalyst.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 26, 2017
    Applicant: API CORPORATION
    Inventors: Naoyuki WATANABE, Tomoko MAEDA, Yasumasa DEKISHIMA, Hiroshi KAWABATA, Masaki NAGAHAMA, Kosuke ITO
  • Publication number: 20170246910
    Abstract: A pneumatic tire is provided in the tread portion 2 with a belt 7 comprising a radially outermost first belt ply 7A and a radially inner second belt ply 7B each composed of belt cords 7C, and a band 8 thereon comprising a band ply 8A compound of a band cord 8C. At least one of axially outer edge portions of the belt 7 is provided between the first belt ply 7A and the second belt ply 7B with a first reinforcing rubber layer 11 having a radially outer surface which is convexed radially outwardly and along which an axially outer edge portion 15 of the first belt ply 7A extends in a mountain shape so as to have an axially inner portion 15a extending axially outwardly and obliquely toward the band ply 8A and an axially outer portion 15b extending axially outwardly and obliquely away from the band ply 8A.
    Type: Application
    Filed: February 3, 2017
    Publication date: August 31, 2017
    Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventor: Hiroshi KAWABATA
  • Publication number: 20170181374
    Abstract: A mid-mount mower has a mower unit mounted under a vehicle body between front wheels and rear wheels. The mower includes a lift link mechanism having a front link and a rear link, an intermediate structure interconnecting one end of the front link and one end of the rear link via a pivot axis, a blade housing having an engaged portion engageable with an engaging potion of the intermediate structure and a guide face configured to guide the engaging portion ad the engaged portion to an engaging position so as to establish connection between the blade housing placed on a ground surface and the intermediate structure in association with a movement of the vehicle body in a front/rear direction.
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Inventors: Hiroyuki Tada, Akira Minoura, Takeshi Komorida, Azusa Furihata, Hiroshi Kawabata, Ryo Matsumoto
  • Publication number: 20170158242
    Abstract: A work vehicle includes a prime mover unit disposed in a front part of the vehicle body, a driving part located in a rear part of the vehicle body, a battery disposed between the prime mover unit and the driving part, a base frame disposed in a lower part of the vehicle body and a center pillar that extends upward from the base frame. The prime mover unit includes a radiator disposed immediately forward of the center pillar. The driving part includes a steering wheel disposed above the battery.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Koichiro Matsumoto, Shoichiro Nagaishi, Ryo Matsumoto, Hiroshi Kawabata, Hiroki Nagai, Masahiro Izumi, Masaki Takaoka, Tasuku Teraoka, Takashi Kumashiro
  • Publication number: 20170129543
    Abstract: A work vehicle includes: a vehicle body frame; a prime mover part that is supported by the vehicle body frame; a bonnet that is configured to vertically swing between a closed position at which the prime mover part is covered, and an open position at which the prime mover part is open; and a support frame that supports a free end side of the bonnet located at the closed position. At least left and right guide-target parts of the bonnet or left and right guiding parts of the support frame have left and right inclined surfaces that serve as centering effective surfaces.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 11, 2017
    Inventors: Koichiro Matsumoto, Nobuyuki Yamashita, Hiroshi Kawabata, Tomohisa Yamamoto, Masayuki Akita, Tasuku Teraoka, Yoshihisa Tonoya
  • Patent number: 9622406
    Abstract: A mid-mount mower has a mower unit mounted under a vehicle body between front wheels and rear wheels. The mower includes a lift link mechanism having a front link and a rear link, an intermediate structure interconnecting one end of the front link and one end of the rear link via a pivot axis, a blade housing having an engaged portion engageable with an engaging potion of the intermediate structure and a guide face configured to guide the engaging portion ad the engaged portion to an engaging position so as to establish connection between the blade housing placed on a ground surface and the intermediate structure in association with a movement of the vehicle body in a front/rear direction.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: April 18, 2017
    Assignee: Kubota Corporation
    Inventors: Hiroyuki Tada, Akira Minoura, Takeshi Komorida, Azusa Furihata, Hiroshi Kawabata, Ryo Matsumoto
  • Patent number: 9512452
    Abstract: The present invention aims to provide a method for efficiently producing hydroxy-L-lysine. The present invention provides a method for producing hydroxy-L-lysine, the method comprising allowing 2-oxoglutarate-dependent L-lysine hydroxylase, a cell containing 2-oxoglutarate-dependent L-lysine hydroxylase, a processed product of the cell, and/or a culture broth obtained by culturing the cell, to act on L-lysine to produce hydroxy-L-lysine represented by the following General Formula (I) (wherein each of R1, R2 and R3 represents a hydrogen atom or hydroxyl group, with the proviso that at least one of R1, R2 and R3 represents a hydroxyl group).
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: December 6, 2016
    Assignee: API Corporation
    Inventors: Kuniki Kino, Ryotaro Hara, Ryoma Miyake, Hiroshi Kawabata
  • Publication number: 20160348081
    Abstract: The present invention provides a pipecolic acid 4-hydroxylase protein exemplified by the following (A), (B), and (C), having activity to react with L-pipecolic acid in the presence of 2-oxoglutaric acid and iron(II) ions to produce trans-4-hydroxy-L-pipecolic acid, and a method for producing 4-hydroxy amino acid, which method comprises reacting the pipecolic acid 4-hydroxylase protein, cells containing the protein, a treated product of the cells, and/or a culture liquid obtained by culturing the cells, with ?-amino acid to produce 4-hydroxy amino acid: (A) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18; (B) a polypeptide comprising the amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 12, 16, or 18 except that one or several amino acids are deleted, substituted, and/or added, and having pipecolic acid 4-hydroxylase activity; and (C) a polypeptide having an amino acid sequence that is not less than 80% identical to the amino acid sequence rep
    Type: Application
    Filed: January 27, 2015
    Publication date: December 1, 2016
    Applicant: API CORPORATION
    Inventors: Makoto HIBI, Jun OGAWA, Ryoma MIYAKE, Hiroshi KAWABATA
  • Publication number: 20160347718
    Abstract: An object of the present invention is to provide a novel method capable of producing rosuvastatin calcium and intermediates therefor efficiently, inexpensively and with high purity. The present invention provides a method of efficiently producing rosuvastatin calcium and intermediates therefor having a high purity at an industrial scale, without using an extremely low temperature reaction or a special asymmetric catalyst.
    Type: Application
    Filed: February 6, 2015
    Publication date: December 1, 2016
    Applicants: API CORPORATION, API CORPORATION
    Inventors: Naoyuki WATANABE, Yasumasa DEKISHIMA, Masaki NAGAHAMA, Tomoko MAEDA, Takashi OHTANI, Kosuke ITO, Hiroshi KAWABATA
  • Patent number: 9334509
    Abstract: It is an object of the present invention to provide a novel hydrolase, which is used when dialkyl 2-vinylcyclopropane-1,1-dicarboxylate is hydrolyzed with an enzyme, so as to efficiently obtain (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid that is useful as an intermediate for synthesizing therapeutic agents for hepatitis C. According to the present invention, there is provided a hydrolase protein, which consists of the amino acid sequence shown in any one of SEQ ID NOS. 2 to 5 and which has activity of catalyzing, at higher selectivity than the protein consisting of the amino acid sequence shown in SEQ ID NO. 1, a reaction of producing (1S,2S)-1-ethoxycarbonyl-2-vinylcyclopropanecarboxylic acid from diethyl 2-vinylcyclopropane-1,1 -dicarboxylate.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: May 10, 2016
    Assignee: API CORPORATION
    Inventors: Hiroshi Kawabata, Ryoma Miyake, Kuniko Asada, Ryouhei Katou
  • Publication number: 20160083341
    Abstract: According to the present invention, it becomes possible to perform a process for converting into an ?-substituted cysteine represented by general formula (1) or a salt thereof at low cost and on an industrial scale by employing a process that is routed through a compound represented by general formula (3) to a compound represented by general formula (6). Particularly, by employing a process that is routed through a compound represented by general formula (7-2), it becomes possible to detach a tert-butyl protection group in a simple manner and to produce the compound represented by general formula (1) with high purity. Furthermore, by employing a process that is routed through tert-butylthiomethanol or a process that is routed through a compound represented by general formula (9), it becomes possible to produce a compound represented by general formula (2) without generating bischloromethylether that is an oncogenic substance.
    Type: Application
    Filed: May 1, 2014
    Publication date: March 24, 2016
    Applicant: API Corporation
    Inventors: Yuuki Asuma, Hisatoshi Uehara, Tomoko Maeda, Yasuyo Saito, Ryoma Miyake, Hiroshi Kawabata
  • Publication number: 20150259715
    Abstract: The present invention aims to provide a method for efficiently producing hydroxy-L-lysine. The present invention provides a method for producing hydroxy-L-lysine, the method comprising allowing 2-oxoglutarate-dependent L-lysine hydroxylase, a cell containing 2-oxoglutarate-dependent L-lysine hydroxylase, a processed product of the cell, and/or a culture broth obtained by culturing the cell, to act on L-lysine to produce hydroxy-L-lysine represented by the following General Formula (I) (wherein each of R1, R2 and R3 represents a hydrogen atom or hydroxyl group, with the proviso that at least one of R1, R2 and R3 represents a hydroxyl group).
    Type: Application
    Filed: February 18, 2014
    Publication date: September 17, 2015
    Applicant: API Corporation
    Inventors: Kuniki Kino, Ryotaro Hara, Ryoma Miyake, Hiroshi Kawabata
  • Publication number: 20150252393
    Abstract: It is an object of the present invention to provide a novel hydrolase, which is used when dialkyl 2-vinylcyclopropane-1,1-dicarboxylate is hydrolyzed with an enzyme, so as to efficiently obtain (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid that is useful as an intermediate for synthesizing therapeutic agents for hepatitis C. According to the present invention, there is provided a hydrolase protein, which consists of the amino acid sequence shown in any one of SEQ ID NOS. 2 to 5 and which has activity of catalyzing, at higher selectivity than the protein consisting of the amino acid sequence shown in SEQ ID NO. 1, a reaction of producing (1S,2S)-1-ethoxycarbonyl-2-vinylcyclopropanecarboxylic acid from diethyl 2-vinylcyclopropane- 1,1 -dicarboxylate.
    Type: Application
    Filed: March 4, 2015
    Publication date: September 10, 2015
    Applicant: API CORPORATION
    Inventors: Hiroshi KAWABATA, Ryoma MIYAKE, Kuniko ASADA, Ryouhei KATOU
  • Patent number: 9079797
    Abstract: The present application relates to a production method for a polycarboxylic acid-based copolymer including a structural unit (I) derived from an unsaturated polyalkylene glycol ether-based monomer (a) and a structural unit (II) derived from an unsaturated carboxylic acid-based monomer (b), in which monomer components including the monomer (a) and the monomer (b) are polymerized using a peroxide and a reductant as polymerization initiators in combination while the pH during polymerization is controlled to 3 or less in the presence of a pH adjustor. The present application also relates to a polycarboxylic acid-based copolymer for a high-performance cement admixture including a structural unit (I) derived from an unsaturated polyalkylene glycol ether-based monomer (a) and a structural unit (II) derived from an unsaturated carboxylic acid-based monomer (b), and a nonpolymerizable organic sulfonic acid having a molecular weight of 300 or less and/or a salt thereof.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: July 14, 2015
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Hiroshi Kawabata, Noboru Sakamoto
  • Publication number: 20150181803
    Abstract: A mid-mount mower has a mower unit mounted under a vehicle body between front wheels and rear wheels. The mower includes a lift link mechanism having a front link and a rear link, an intermediate structure interconnecting one end of the front link and one end of the rear link via a pivot axis, a blade housing having an engaged portion engageable with an engaging potion of the intermediate structure and a guide face configured to guide the engaging portion ad the engaged portion to an engaging position so as to establish connection between the blade housing placed on a ground surface and the intermediate structure in association with a movement of the vehicle body in a front/rear direction.
    Type: Application
    Filed: September 18, 2014
    Publication date: July 2, 2015
    Inventors: Hiroyuki Tada, Akira Minoura, Takeshi Komorida, Azusa Furihata, Hiroshi Kawabata, Ryo Matsumoto