Patents by Inventor Hiroshi Kawabata
Hiroshi Kawabata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9061991Abstract: It is an object of the present invention to provide a novel method for producing (1R,2S)/(1S,2R)-1-amino-1-alkoxycarbonyl-2-vinylcyclopropane which is useful as a synthetic intermediate of therapeutic agents for hepatitis C and a synthetic intermediate thereof. According to the present invention, when a trans-2-butene derivative having a leaving group at each of the 1- and 4-positions is reacted with a malonic ester in the presence of a base, a specific amount of an alkali metal alkoxide or an alkali metal hydride is used as the base, and further a specific amount of a malonic ester is used to produce a cyclopropane diester, and further, chiral or achiral 1-amino-1-alkoxy-carbonyl-2-vinylcyclopropane and a salt thereof are synthesized using the cyclopropane diester.Type: GrantFiled: February 16, 2011Date of Patent: June 23, 2015Assignee: API CORPORATIONInventors: Yuuki Asuma, Tatsuya Suzuki, Jun Takehara, Tsugihiko Hidaka, Kuniko Asada, Ryoma Miyake, Yasumasa Dekishima, Hiroshi Kawabata
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Patent number: 9029107Abstract: It is an object of the present invention to provide a novel hydrolase, which is used when dialkyl 2-vinylcyclopropane-1,1-dicarboxylate is hydrolyzed with an enzyme, so as to efficiently obtain (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid that is useful as an intermediate for synthesizing therapeutic agents for hepatitis C. According to the present invention, there is provided a hydrolase protein, which consists of the amino acid sequence shown in any one of SEQ ID NOS. 2 to 5 and which has activity of catalyzing, at higher selectivity than the protein consisting of the amino acid sequence shown in SEQ ID NO. 1, a reaction of producing (1S,2S)-1-ethoxycarbonyl-2-vinylcyclopropanecarboxylic acid from diethyl 2-vinylcyclopropane-1,1-dicarboxylate.Type: GrantFiled: August 31, 2011Date of Patent: May 12, 2015Assignee: API CorporationInventors: Hiroshi Kawabata, Ryoma Miyake, Kuniko Asada, Ryouhei Katou
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Publication number: 20140127762Abstract: The present invention aims to provide an industrial method practically suitable for producing optically active ?-substituted prolines from an acyclic ketone compound by a small number of steps under mild conditions. The present invention relates to a production method of an optically active ?-substituted proline (4) and/or an optically active ?-substituted prolinamide (5), including (a) reacting an acyclic ketone compound (1) with at least one selected from ammonia, an ammonium salt, primary amine and a salt of primary amine, and a cyanating agent to give a cyclic nitrogen-containing compound (2), (b) hydrating the cyclic nitrogen-containing compound (2) to give an ?-substituted prolinamide (3), and (c) resolving the ?-substituted prolinamide (3) by one or more of (d) enzymatical hydrolysis, (e) resolution by diastereomeric salt formation, and (f) separation by column chromatography.Type: ApplicationFiled: March 29, 2012Publication date: May 8, 2014Inventors: Hisatoshi Uehara, Ryoma Miyake, Keisuke Bando, Hiroshi Kawabata, Tomoko Maeda
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Publication number: 20130184420Abstract: To provide a monomer composition containing an unsaturated polyalkylene glycol ether-based monomer and having excellent stability. Provided is a monomer composition containing an unsaturated polyalkylene glycol ether-based monomer represented by the following chemical formula (1): YO(R1O)nR2??(1) [in the formula, Y represents an alkenyl group having 2 to 7 carbon atoms; R1O represents one or two or more types of oxyalkylene groups having 2 to 18 carbon atoms; n represents an average addition mole number of oxyalkylene groups and is a number of 5 to 500; and R2 represents a hydrogen atom or a hydrocarbon group having 1 to 30 carbon atoms], an organic acid, and water, and having a pH of 4 to 13.Type: ApplicationFiled: September 22, 2011Publication date: July 18, 2013Applicant: NIPPON SHOKUBAI CO., LTD.Inventor: Hiroshi Kawabata
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Publication number: 20130130338Abstract: It is an object of the present invention to provide a novel hydrolase, which is used when dialkyl 2-vinylcyclopropane-1,1-dicarboxylate is hydrolyzed with an enzyme, so as to efficiently obtain (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid that is useful as an intermediate for synthesizing therapeutic agents for hepatitis C. According to the present invention, there is provided a hydrolase protein, which consists of the amino acid sequence shown in any one of SEQ ID NOS. 2 to 5 and which has activity of catalyzing, at higher selectivity than the protein consisting of the amino acid sequence shown in SEQ ID NO. 1, a reaction of producing (1S,2S)-1-ethoxycarbonyl-2-vinylcyclopropanecarboxylic acid from diethyl 2-vinylcyclopropane-1,1-dicarboxylate.Type: ApplicationFiled: August 31, 2011Publication date: May 23, 2013Applicant: API CORPORATIONInventors: Hiroshi Kawabata, Ryoma Miyake, Kuniko Asada, Ryouhei Katou
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Publication number: 20130096339Abstract: It is an object of the present invention to provide a novel method for producing (1R,2S)/(1S,2R)-1-amino-1-alkoxycarbonyl-2-vinylcyclopropane which is useful as a synthetic intermediate of therapeutic agents for hepatitis C and a synthetic intermediate thereof. According to the present invention, when a trans-2-butene derivative having a leaving group at each of the 1- and 4-positions is reacted with a malonic ester in the presence of a base, a specific amount of an alkali metal alkoxide or an alkali metal hydride is used as the base, and further a specific amount of a malonic ester is used to produce a cyclopropane diester, and further, chiral or achiral 1-amino-1-alkoxy-carbonyl-2-vinylcyclopropane and a salt thereof are synthesized using the cyclopropane diester.Type: ApplicationFiled: February 16, 2011Publication date: April 18, 2013Applicant: API CORPORATIONInventors: Yuuki Asuma, Tatsuya Suzuki, Jun Takehara, Tsugihiko Hidaka, Kuniko Asada, Ryoma Miyake, Yasumasa Dekishima, Hiroshi Kawabata
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Patent number: 8374647Abstract: A mobile terminal is provided which is capable of managing contact-less card function content, while acquiring and deleting the contact-less card function content with ease. The mobile terminal according to the present invention has a terminal operating system (OS) that executes various functions of the mobile terminal, a Felica application manager (FAM), a Felica device driver that drives a Felica OS according to control of the FAM, and a Felica chip that stores Felica content. The FAM operates a Java applications manager that manages Java applications having the network computing function, API to start a browser, that executes API, and other applications such as a the browser, a menu and a Felica viewer.Type: GrantFiled: September 1, 2005Date of Patent: February 12, 2013Assignee: NTT Docomo, Inc.Inventors: Tomohiro Ando, Hiroshi Kawabata, Satoshi Washio
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Patent number: 8297386Abstract: A work vehicle including: a body frame; an engine supported by the body frame through an elastic body; a belt transmission mechanism connected to an output shaft of the engine in a power transmissive manner; and a power takeoff (PTO) mechanism connected to the belt transmission mechanism in a power transmissive manner to take out power from the engine. A PTO support bracket configured to support the PTO mechanism is attached to the engine.Type: GrantFiled: March 5, 2009Date of Patent: October 30, 2012Assignee: Kubota CorporationInventors: Masashi Osuga, Shoko Koda, Hironobu Nishihara, Takashi Kuramoto, Satoshi Ogata, Hiroshi Kawabata
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Patent number: 8281391Abstract: Mobile unit 16 which can activate Java-AP software receives SDF (Security Descriptive File) 204 from administering server unit 18 which a trustworthy organization (a communication provider which administers mobile packet communication network 15) administers, and obtains ADF 205 from IP server unit 13 by using URL contained in the SDF, and obtains Jar file 206 from IP server unit 13 by using ADF 205, and installs in itself Java-AP containing these files. Java-AP, which is achieved by activating the installed Java-AP software, operates within the range of authorization expressed by policy information contained in SDF 204.Type: GrantFiled: February 27, 2009Date of Patent: October 2, 2012Assignee: NTT DoCoMo, Inc.Inventors: Kazuhiro Yamada, Nobuyuki Watanabe, Masayuki Tsuda, Dai Kamiya, Mao Asai, Fumiaki Miura, Satoshi Washio, Atsuki Tomioka, Hiroshi Kawabata, Takashi Kondo
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Patent number: 8166291Abstract: Management server 16 may obtain application programs from content server 20 in response to requests of mobile terminal 11. Management server 16 may transmit the obtained application programs to mobile terminal 11 with information concerning reliabilities of the application programs. After mobile terminal 11 receives the application programs from management server 16, mobile terminal 11 manages operations of the application programs. Operations of the application programs are coordinated with operations of other programs using the information concerning the reliabilities corresponding to the application programs. Management of the coordinated operations of the application programs avoids problems concerning information security, where valuable information may be distributed unexpectedly because of operations of low reliable application programs. As a result, convenience of users of mobile terminals 11 can be improved without deteriorating the information security of mobile terminals 11.Type: GrantFiled: May 8, 2008Date of Patent: April 24, 2012Assignee: NTT DoCoMo, Inc.Inventors: Takeshi Natsuno, Masaaki Yamamoto, Satoshi Washio, Hiroshi Kawabata
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Patent number: 8140846Abstract: Management server 16 may obtain application programs from content server 20 in response to requests of mobile terminal 11. Management server 16 may transmit the obtained application programs to mobile terminal 11 with information concerning reliabilities of the application programs. After mobile terminal 11 receives the application programs from management server 16, mobile terminal 11 manages operations of the application programs. Operations of the application programs are coordinated with operations of other programs using the information concerning the reliabilities corresponding to the application programs. Management of the coordinated operations of the application programs avoids problems concerning information security, where valuable information may be distributed unexpectedly because of operations of low reliable application programs. As a result, convenience of users of mobile terminals 11 can be improved without deteriorating the information security of mobile terminals 11.Type: GrantFiled: May 8, 2008Date of Patent: March 20, 2012Assignee: NTT DoCoMo, Inc.Inventors: Takeshi Natsuno, Masaaki Yamamoto, Satoshi Washio, Hiroshi Kawabata
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Patent number: 8056306Abstract: A rear discharge mower comprising: a first shaft; a first blade that is rotated in unison with the first shaft; a second shaft that is configured to be rotated in a direction opposite from a rotational direction of the first shaft; a second blade that is rotated in unison with the second shaft, wherein a grass-clippings discharge path is formed through which grass clippings are discharged in a rearward direction from the area between the first shaft and second shaft; an enclosing casing that supports the blade shafts; and a power train that is accommodated in the enclosing casing and that transmits power to the first and second blade shafts.Type: GrantFiled: August 20, 2009Date of Patent: November 15, 2011Assignee: Kubota CorporationInventors: Kenji Nishihara, Takashi Kuramoto, Masashi Osuga, Takashi Shibata, Satoshi Ogata, Hironobu Nishihara, Hiroshi Kawabata
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Patent number: 8051631Abstract: A rear discharge mower comprising: a first shaft; a first blade that is rotated in unison with the first shaft; a second shaft that is configured to be rotated in a direction opposite from a rotational direction of the first shaft; a second blade that is rotated in unison with the second shaft, wherein a grass-clippings discharge path is formed through which grass clippings are discharged in a rearward direction from the area between the first shaft and second shaft; an enclosing casing that supports the blade shafts; and a power train that is accommodated in the enclosing casing and that transmits power to the first and second blade shafts.Type: GrantFiled: March 19, 2008Date of Patent: November 8, 2011Assignee: Kubota CorporationInventors: Kenji Nishihara, Takashi Kuramoto, Masashi Osuga, Takashi Shibata, Satoshi Ogata, Hironobu Nishihara, Hiroshi Kawabata
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Patent number: 8015616Abstract: Mobile unit 16 which can activate Java-AP software receives SDF (Security Descriptive File) 204 from administering server unit 18 which a trustworthy organization (a communication provider which administers mobile packet communication network 15) administers, and obtains ADF 205 from IP server unit 13 by using URL contained in the SDF, and obtains Jar file 206 from IP server unit 13 by using ADF 205, and installs in itself Java-AP containing these files. Java-AP, which is achieved by activating the installed Java-AP software, operates within the range of authorization expressed by policy information contained in SDF 204.Type: GrantFiled: February 27, 2009Date of Patent: September 6, 2011Assignee: NTT DoCoMo, Inc.Inventors: Kazuhiro Yamada, Nobuyuki Watanabe, Masayuki Tsuda, Dai Kamiya, Mao Asai, Fumiaki Miura, Satoshi Washio, Atsuki Tomioka, Hiroshi Kawabata, Takashi Kondo
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Patent number: 8010095Abstract: Management server 16 may obtain application programs from content server 20 in response to requests of mobile terminal 11. Management server 16 may transmit the obtained application programs to mobile terminal 11 with information concerning reliabilities of the application programs. After mobile terminal 11 receives the application programs from management server 16, mobile terminal 11 manages operations of the application programs. Operations of the application programs are coordinated with operations of other programs using the information concerning the reliabilities corresponding to the application programs. Management of the coordinated operations of the application programs avoids problems concerning information security, where valuable information may be distributed unexpectedly because of operations of low reliable application programs. As a result, convenience of users of mobile terminals 11 can be improved without deteriorating the information security of mobile terminals 11.Type: GrantFiled: May 8, 2008Date of Patent: August 30, 2011Assignee: NTT DoCoMo, Inc.Inventors: Takeshi Natsuno, Masaaki Yamamoto, Satoshi Washio, Hiroshi Kawabata
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Patent number: 8001375Abstract: A mobile device (10) has a noncontact IC (11). Three storage areas are preliminarily formed in the noncontact IC (11). When the mobile device (10) receives an application from a content server (20), a storage area (1) is assigned as a data area dedicated to this application. After that, the mobile device (10) rejects access from any application other than the foregoing application to the storage area (1).Type: GrantFiled: June 6, 2005Date of Patent: August 16, 2011Assignee: NTT DoCoMo, Inc.Inventors: Yasunori Hattori, Hisashi Yoshinaga, Hiroshi Kawabata, Satoshi Washio
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Publication number: 20110065847Abstract: Provided is a production method for a polycarboxylic acid-based copolymer including a structural unit derived from an unsaturated polyalkylene glycol ether-based monomer and a structural unit derived from an unsaturated carboxylic acid-based monomer, by which the production cost of the copolymer is reduced and an unprecedentedly high-performance cement admixture can be provided. Also provided is a copolymer composition for a cement admixture, including a structural unit derived from an unsaturated polyalkylene glycol ether-based monomer and a structural unit derived from an unsaturated carboxylic acid-based monomer, with which an unprecedentedly high-performance cement admixture can be provided.Type: ApplicationFiled: May 8, 2009Publication date: March 17, 2011Applicant: Nippon Shokubai Co., Ltd.Inventors: Hiroshi Kawabata, Noboru Sakamoto
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Patent number: 7848780Abstract: In a communication terminal using UIM, when a message disabling use of a content is received not by a communication terminal containing the content to disabled, but by another communication terminal containing the same content, the content stored in a storage unit of the communication terminal which has received the message is not disabled. Mobile phone 100-1 using UIM stores a program in correlation with a telephone number stored in the UIM. When mobile phone 100-1 receives a management message to delete a program, mobile phone 100-1 interprets the content of the management message. Mobile phone 100-1 obtains a telephone number from the UIM, and deletes the content stored in correlation with the telephone number according to the management message interpreted.Type: GrantFiled: December 15, 2004Date of Patent: December 7, 2010Assignee: NTT DoCoMo, Inc.Inventors: Satoshi Washio, Hiroshi Kawabata, Tomoo Yamaguchi
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Patent number: 7802726Abstract: In a system according to the invention, a communication section of a mobile terminal detects a carrier from an external R/W, starts communication with the external R/W, and acquires content simplified data of contactless card function content from the external R/W. The acquired content simplified data is transferred to a control section using the contactless card function content and stored. Further, in this system, by connecting to a URL contained in the content simplified data, content body data of the contactless card function content corresponding to the content simplified data is downloaded and stored in the mobile terminal.Type: GrantFiled: November 7, 2005Date of Patent: September 28, 2010Assignee: NTT DoCoMo, Inc.Inventors: Tomohiro Ando, Naoki Yamane, Hiroshi Kawabata, Satoshi Washio
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Patent number: 7742756Abstract: Management server 16 may obtain application programs from content server 20 in response to requests of mobile terminal 11. Management server 16 may transmit the obtained application programs to mobile terminal 11 with information concerning reliabilities of the application programs. After mobile terminal 11 receives the application programs from management server 16, mobile terminal 11 manages operations of the application programs. Operations of the application programs are coordinated with operations of other programs using the information concerning the reliabilities corresponding to the application programs. Management of the coordinated operations of the application programs avoids problems concerning information security, where valuable information may be distributed unexpectedly because of operations of low reliable application programs. As a result, convenience of users of mobile terminals 11 can be improved without deteriorating the information security of mobile terminals 11.Type: GrantFiled: May 8, 2008Date of Patent: June 22, 2010Assignee: NTT DoCoMo, Inc.Inventors: Takeshi Natsuno, Masaaki Yamamoto, Satoshi Washio, Hiroshi Kawabata