Abstract: A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of a mucosal adjuvant. The mucosal vaccine comprises a composite of a nanogel comprising a hydrophilic polysaccharide having a cationic functional group and a hydrophobic cholesterol added thereto as a side chain and a vaccine antigen. The vaccine is administered via a mucosal route.

Abstract: A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of a mucosal adjuvant. The mucosal vaccine comprises a composite of a nanogel comprising a hydrophilic polysaccharide having a cationic functional group and a hydrophobic cholesterol added thereto as a side chain and a vaccine antigen. The vaccine is administered via a mucosal route.

Abstract: A magnetic disk device includes: a recording medium provided with a plurality of write tracks; a magnetic write head including a magnetic pole, side shields, and a leading shield, a distance from the magnetic pole to each of the side shields being maintained to be uniform with a gap layer therebetween, and a distance from the magnetic pole to the leading shield being maintained to be uniform with a gap layer therebetween; and a control section rotating the recording medium, and allowing magnetic information to be recorded on the recording medium while allowing the magnetic write head to travel in a direction from an inner write track toward an outer write track or in a direction from the outer write track toward the inner write track, across write tracks in the recording medium. With such a configuration, format efficiency may be improved, and a width of an erase band on a magnetic disk may be minimized.

Abstract: In exemplary embodiments, first and second parameters are obtained for each of different temperatures of the magnetic recording layer. The absolute value of the first parameter for each magnetic grain has a minimum value when the temperature of each magnetic grain reaches a predetermined temperature that increases as the Curie temperature increases, and decreases as the Curie temperature decreases. The second parameter is related to the standard deviation of the coercivity distribution of the magnetic grains divided by the coercivity of the magnetic recording layer. The method calculates a value where the absolute measurement value of the first parameter has a minimum value and the temperature of the magnetic recording layer at which the standard deviation of the coercivity distribution of the magnetic grains divided by the coercivity of the magnetic recording layer has a maximum value.

Abstract: A measurement method of a magnetic field gradient of a recording magnetic field generated by a magnetic head in a recording medium includes a step of locally heating the recording medium in a nonmagnetic field state where a magnetic field is not applied to the recording medium at all and measuring a temperature gradient of the recording medium in the nonmagnetic field state, a step of locally heating the recording medium in a recording magnetic field application state where the recording magnetic field is applied to the recording medium and measuring a temperature gradient of the recording medium in the recording magnetic field application state, and a step of calculating a magnetic field gradient of the recording magnetic field based on the temperature gradient of the recording medium in the nonmagnetic field state and the temperature gradient of the recording medium in the recording magnetic field application state.

Abstract: A magnetic head slider includes a near-field light generator, an incorporated heater is activated to thermally-expand the magnetic head slider so that a first protrusion is generated on the air bearing surface, and a second protrusion protruding from the first protrusion is generated by a thermal expansion of the near-field light generator. A standard signal is written to a recording medium with a predetermined magnetization. A relation between a residual magnetization of the standard signal and a power of the heater is obtained by lowering the magnetization of the standard signal by heating the recording medium with the near-field light while light output of laser light is maintained to be constant and the power of the heater is varied. Further, a relation between the first spacing and the residual magnetization is obtained.

Abstract: A magnetic head slider includes a near-field light generator, an incorporated heater is activated to thermally-expand the magnetic head slider so that a first protrusion is generated on the air bearing surface, and a second protrusion protruding from the first protrusion is generated by a thermal expansion of the near-field light generator. A standard signal is written to a recording medium with a predetermined magnetization. A relation between a residual magnetization of the standard signal and a power of the heater is obtained by lowering the magnetization of the standard signal by heating the recording medium with the near-field light while light output of laser light is maintained to be constant and the power of the heater is varied. Further, a relation between the first spacing and the residual magnetization is obtained.

Abstract: A thermally-assisted magnetic recording method includes first and second steps. The first step applies heat to part of a hard disk medium and forms a moving high-temperature region in a magnetic recording layer of the hard disk medium. The high-temperature region is higher in temperature than a region therearound and has a temperature equal to or higher than the maximum coercivity vanishing temperature of a plurality of magnetic grains contained in the magnetic recording layer. At least one magnetic grain that is adjacent to the rear end of the high-temperature region in the direction of movement of the high-temperature region has a coercivity of a value other than 0. The second step applies a write magnetic field to the hard disk medium such that the write magnetic field applied to the at least one magnetic grain adjacent to the rear end of the high-temperature region is 3 kOe or smaller in magnitude.

Abstract: A magnetic disk device includes: a recording medium provided with a plurality of write tracks; a magnetic write head including a magnetic pole, side shields, and a leading shield, a distance from the magnetic pole to each of the side shields being maintained to be uniform with a gap layer therebetween, and a distance from the magnetic pole to the leading shield being maintained to be uniform with a gap layer therebetween; and a control section rotating the recording medium, and allowing magnetic information to be recorded on the recording medium while allowing the magnetic write head to travel in a direction from an inner write track toward an outer write track or in a direction from the outer write track toward the inner write track, across write tracks in the recording medium. With such a configuration, format efficiency may be improved, and a width of an erase band on a magnetic disk may be minimized.

Abstract: In a method of estimating the Curie temperature distribution of a plurality of magnetic grains contained in a magnetic recording layer, measurement values of first and second parameters are obtained for each of different temperatures of the magnetic recording layer which is used as the measurement subject. The first parameter has such a property that the absolute value of the first parameter for each magnetic grain takes on the minimum value when the temperature of each magnetic grain reaches a predetermined temperature, wherein the predetermined temperature varies according to the Curie temperature of each magnetic grain in such a manner as to increase as the Curie temperature increases, and to decrease as the Curie temperature decreases. The second parameter is related to the standard deviation of the coervicity distribution of the magnetic grains divided by the coervicity of the magnetic recording layer.

Abstract: A thermally-assisted magnetic recording method includes first and second steps. The first step applies heat to part of a hard disk medium and forms a moving high-temperature region in a magnetic recording layer of the hard disk medium. The high-temperature region is higher in temperature than a region therearound and has a temperature equal to or higher than the maximum coercivity vanishing temperature of a plurality of magnetic grains contained in the magnetic recording layer. At least one magnetic grain that is adjacent to the rear end of the high-temperature region in the direction of movement of the high-temperature region has a coercivity of a value other than 0. The second step applies a write magnetic field to the hard disk medium such that the write magnetic field applied to the at least one magnetic grain adjacent to the rear end of the high-temperature region is 3 kOe or smaller in magnitude.

Abstract: A thin film magnetic head includes a medium projection detection mechanism that detects a projection on the surface of a recording medium. The medium projection detection mechanism has a discharging electrode, a capacitor, and an input line and an output line that are connected to the discharging electrode. The discharging electrode is configured to receive a voltage applied through the input line, and the capacitor is configured to store electric charge by the applied voltage. The output line is connected to a projection detection processing system and is connected to the charging electrode and the projection detection processing system to detect the location of the projection that is a detection target by detecting voltage change that is caused by discharging between the discharging electrode and the projection when the projection is detected.

Abstract: A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of a mucosal adjuvant. The mucosal vaccine comprises a composite of a nanogel comprising a hydrophilic polysaccharide having a cationic functional group and a hydrophobic cholesterol added thereto as a side chain and a vaccine antigen. The vaccine is administered via a mucosal route.

Abstract: It is an object of the present invention to provide a method for investigating magnetic domains, the method capable of easily grasping behavior of the magnetic domains in a head manufacturing process, and further to provide a testing method of a magnetic head capable of evaluating whether the writing performance of the magnetic head is good or not. The method for investigating magnetic domains comprises supplying direct current (DC) to a coil of an electromagnetic transducer provided in a magnetic head for writing data onto a magnetic recording medium; measuring an inductance of the electromagnetic transducer at each current value while varying the current value of the direct current; and investigating behavior of magnetic domains in a magnetic core of the electromagnetic transducer based on a relationship between the current values and the inductances.

Abstract: A thin film magnetic head includes a medium projection detection mechanism that detects a projection on the surface of a recording medium. The medium projection detection mechanism has a discharging electrode, a capacitor, and an input line and an output line that are connected to the discharging electrode. The discharging electrode is configured to receive a voltage applied through the input line, and the capacitor is configured to store electric charge by the applied voltage. The output line is connected to a projection detection processing system and is connected to the charging electrode and the projection detection processing system to detect the location of the projection that is a detection target by detecting voltage change that is caused by discharging between the discharging electrode and the projection when the projection is detected.

Abstract: A TMR effect element with sufficiently reduced element resistance and restricted popping noise is provided, which comprises a tunnel barrier layer formed primarily of a metal oxide including many electric charge sites. The electric charge sites density n and the mobility ? of electrons trapped due to the electric charge sites satisfy a relationship expressed by: 0<(ns1?1?ns2?1)?1·(?0??)·(n?)?1<0.2, where ns1 and ns2 are densities of tunnel electrons when an element resistance is a minimum and maximum respectively during reading signals and ?0 is the mobility of electrons when not trapped.

Abstract: The invention provides a thin-film magnetic head having a magneto-resistive effect device of the CPP (current perpendicular to plane) structure comprising a multilayer film in which a fixed magnetization layer, a nonmagnetic layer and a free layer are stacked together in order. The fixed magnetization layer, nonmagnetic layer and free layer extend away from an air bearing surface that is a plane in opposition to a medium, the length of the fixed magnetization layer in a depth direction normal to said air bearing surface is greater than the length of the free layer in the depth direction. A shunt layer for shunting the sense current is located at a farther distance in the depth direction than the free layer, and the shunt layer is separated from the free layer by a constant gap in the depth direction.

Abstract: The present invention has objectives of providing a low-cost, easy-to-handle individual isolation animal breeding unit and a system for using the same, significantly reducing costs of facilities and maintenance for animal experiments and saving on labor, and providing a new animal transportation form. For achieving the objectives, the present invention provides a system for maintaining an animal breeding environment, comprising A) an animal breeding unit capable of comprising an internal tray having a sufficient space for breeding an animal of interest, comprising an external tray capable of accommodating the internal tray, and capable of keeping a predetermined cleanliness degree; B) a method for providing the internal tray having the predetermined cleanliness degree; C) an internal tray exchange unit capable of accommodating the animal breeding unit and exchanging the internal tray while keeping the predetermined cleanliness degree; and D) a method for recovering the exchanged internal tray.

Abstract: A method of measuring a magnetic write width includes forming a data track on a discrete track medium by a write operation at a first frequency, performing write operations at a second frequency that is different from the first frequency, at both side positions along the formed data track, obtaining a track profile by scanning the data track in a track-width direction, using a magnetic field detection element, calculating an integrated profile of the obtained track profile, obtaining profile integrals by setting a distance from the data track to a position of the write operations at the second frequency to various values and by calculating the profile integrals for the respective values of the distance, and calculating a magnetic write width of the magnetic head and a magnetic write width of the discrete track medium from a relationship between the distance and the profile integrals.

Abstract: The head slider has a plurality of heaters each heating a corresponding region of the ABS, and a sensor detecting collision of the ABS with a projection on a surface of the magnetic disk. Currents supplied to the respective heaters are controlled and produce heats independently of one another. The heats produce projections on the corresponding regions of the ABS, respectively. The ABS with asperity can be planarized through appropriately controlling magnitude of the currents supplied to the heaters. Thus, the variation of a sensor output depending on asperity of the ABS is effectively reduced. Another head slider has a heater locally heating a corresponding region of the ABS. The heater has a structure where a central portion is away from the ABS compared with end portions, or a structure where calorific power of a central portion is smaller than that of each of end portions. Thus, overall projection shape becomes flat.