Patents by Inventor Hiroyuki Kawai

Hiroyuki Kawai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11028120
    Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: June 8, 2021
    Assignee: ORIC PHARMACEUTICALS, INC.
    Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai, Chien-Hung Yeh
  • Publication number: 20210130389
    Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.
    Type: Application
    Filed: October 29, 2020
    Publication date: May 6, 2021
    Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
  • Publication number: 20210130390
    Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.
    Type: Application
    Filed: December 8, 2020
    Publication date: May 6, 2021
    Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
  • Publication number: 20210122730
    Abstract: Described herein are glucocorticoid receptor modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer and hypercortisolism.
    Type: Application
    Filed: April 10, 2018
    Publication date: April 29, 2021
    Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Yosup REW, Daqing SUN, Qiuping YE, Haiying ZHOU, Hiroyuki KAWAI, Jared MOORE, Johnny PHAM, Kejia WU, Liusheng ZHU, Dennis YAMASHITA
  • Patent number: 10981513
    Abstract: A center console structure includes a columnar part erected on a vehicle interior floor surface between a driver seat and a passenger seat and extends upward to the vicinity of the cushion surfaces of the seats and an upper body that is disposed above the columnar part, extends in a front-rear direction, has an upper surface part forming a center console surface, and accommodates a shift operation mechanism, in which the upper body extends forward of the columnar part that is cantilevered and has an extension part that is bent and then rises forward and obliquely upward in the front part thereof, a surface part of the extension part close to a sitting occupant forms an outer surface continuous with the center console surface and a portion of the extension part close to the front of the vehicle is locked to a rear projecting part of an instrument panel.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: April 20, 2021
    Assignee: MAZDA MOTOR CORPORATION
    Inventors: Hiroyuki Kawai, Masanori Taguchi, Eiji Okada, Junko Karube, Yamato Matsuda, Yohichi Yanagi, Kazuki Hikawa, Junko Nakamura, Koji Miyamoto, Atsuo Iwabuchi, Hidehiko Soda, Ryoichi Hashimoto
  • Publication number: 20210111463
    Abstract: To provide a separator which has a combination of a preferable air permeability enabling high prevention of internal short circuit and a high retention rate of such an air permeability in an electrolytic solution, and has more improved uniformity of the air permeability. A separator comprising a porous sheet and cellulose nanofibers, wherein the porous sheet comprises a binder component having the SP value of 11 to 16 (cal/cm3)1/2, and the porous sheet has the cellulose nanofibers at the inside and on the surface thereof, and wherein the cellulose nanofibers are combined with the porous sheet by fusion of the binder component.
    Type: Application
    Filed: December 25, 2018
    Publication date: April 15, 2021
    Applicant: KURARAY CO., LTD.
    Inventors: Tomoki SAKAI, Hiroyuki KAWAI, Tomohiro HAYAKAWA, Toshimichi KUSUNOKI
  • Publication number: 20210047359
    Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 18, 2021
    Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai
  • Patent number: 10890190
    Abstract: A magnetic pump includes a front casing including: a shaft supporting body that supports a leading end of a supporting shaft; and a plurality of supporting legs that extends toward an inner wall of a suction port from the shaft supporting body, and that supports the shaft supporting body in the suction port. In the magnetic pump, a leading end of the shaft supporting body is positioned further toward the inlet side of the suction port than a connecting section between the inner wall of the suction port and the supporting leg.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: January 12, 2021
    Assignee: IWAKI CO., LTD.
    Inventors: Hiroyuki Kawai, Katsumi Kawaguchi, Toshinori Yanagihara
  • Publication number: 20200261836
    Abstract: Provided is a granular filtration media comprising a mixture of granular filtration media and less than 2.5% of nanofibers based on the dry weight, method of making the same and uses of the same for removing contaminants from water, including metals, heavy metals, synthetic or natural organic matters, colloidal or suspended particles to improve the chemical safety and purity of water for the purpose of water purification, specifically, one embodiment of the present invention disclosed is use of the granular filtration media to remove particulate lead from high pH water.
    Type: Application
    Filed: May 6, 2020
    Publication date: August 20, 2020
    Applicant: STRIX (USA), Inc.
    Inventors: Yongjun Chen, Hiroyuki Kawai, Patricia Q. Bottari, Christopher R. Ashley, Andrew F. Mason
  • Patent number: 10668416
    Abstract: Provided is a granular filtration media comprising a mixture of granular filtration media and less than 5% of nanofibers based on the dry weight, method of making the same and uses of the same for removing contaminants from water, including metals, heavy metals, synthetic or natural organic matters, colloidal or suspended particles to improve the chemical safety and purity of water for the purpose of water purification, specifically, one embodiment of the present invention disclosed is use of the granular filtration media to remove particulate lead from high pH water.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: June 2, 2020
    Assignee: STRIX (USA), INC.
    Inventors: Yongjun Chen, Hiroyuki Kawai, Patricia Q. Bottari, Christopher R. Ashley, Andrew F. Mason
  • Patent number: 10533287
    Abstract: Provided is a dispersant for carbon fibers which allows uniform dispersion of relatively long carbon fibers, e.g., carbon fibers with a length of 12.5 mm or more, particularly 10.0-100.0 mm, more particularly 12.5-50.0 mm in an aqueous medium. A dispersant for carbon fibers used by combining: (A) a random copolymer of phenylglycidyl ether and ethylene oxide, or a random copolymer of phenylglycidyl ether, ethylene oxide and propylene oxide; and (B) a polyether-based polyurethane resin based on a bifunctional polyol and hexamethylene diisocyanate, the bifunctional polyol being polyethylene glycol and/or an ethylene oxide-propylene oxide random copolymer.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: January 14, 2020
    Assignee: KURARAY CO., LTD.
    Inventors: Tomohiro Hayakawa, Toshimichi Kusunoki, Hiroyuki Kawai, Hideo Kiyoyama
  • Publication number: 20190366936
    Abstract: A center console structure includes a columnar part erected on a vehicle interior floor surface between a driver seat and a passenger seat and extends upward to the vicinity of the cushion surfaces of the seats and an upper body that is disposed above the columnar part, extends in a front-rear direction, has an upper surface part forming a center console surface, and accommodates a shift operation mechanism, in which the upper body extends forward of the columnar part that is cantilevered and has an extension part that is bent and then rises forward and obliquely upward in the front part thereof, a surface part of the extension part close to a sitting occupant forms an outer surface continuous with the center console surface and a portion of the extension part close to the front of the vehicle is locked to a rear projecting part of an instrument panel.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 5, 2019
    Applicant: MAZDA MOTOR CORPORATION
    Inventors: Hiroyuki KAWAI, Masanori TAGUCHI, Eiji OKADA, Junko KARUBE, Yamato MATSUDA, Yohichi YANAGI, Kazuki HIKAWA, Junko NAKAMURA, Koji MIYAMOTO, Atsuo IWABUCHI, Hidehiko SODA, Ryoichi HASHIMOTO
  • Publication number: 20190366935
    Abstract: A center console structure includes a metal internal frame that supports a shift operation mechanism, and an outer sheath body made of resin that encloses the internal frame and forms a dressed surface. A front side part of the internal frame is slanted so that an upper member is positioned forward and obliquely upward of a base part member closer to the floor surface, and a storage part is formed in front of the base part member in which a bottom part extending in a vehicle front-rear direction to a position immediately below an instrument panel is provided. Both left and right side walls of the bottom part are surrounded by left and right fence parts formed by extending lower parts of left and right side wall parts of the outer sheath body forward, a rear part is surrounded by a front lower part of the outer sheath body.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 5, 2019
    Applicant: MAZDA MOTOR CORPORATION
    Inventors: Hiroyuki KAWAI, Masanori TAGUCHI, Eiji OKADA, Junko KARUBE, Yamato MATSUDA, Yohichi YANAGI, Kazuki HIKAWA, Junko NAKAMURA, Koji MIYAMOTO, Atsuo IWABUCHI, Hidehiko SODA, Ryoichi HASHIMOTO
  • Publication number: 20190360149
    Abstract: To provide a thermoplastic resin fiber to which a dispersant is attached, which can effectively disperse carbon fibers. A thermoplastic resin fiber to which a dispersant containing a random copolymer (A) of glycidyl ether and an alkylene oxide is attached in an amount of 0.1 to 20% by mass based on a total mass of thermoplastic resin fibers to which a dispersant is not attached.
    Type: Application
    Filed: December 26, 2017
    Publication date: November 28, 2019
    Applicant: KURARAY CO., LTD.
    Inventors: Tomoki SAKAI, Hiroyuki KAWAI, Tomohiro HAYAKAWA, Toshimichi KUSUNOKI
  • Patent number: 10461294
    Abstract: Provided are an alkaline battery separator suitably used for an alkaline battery, and an alkaline battery using the separator. The separator includes a nonwoven fabric including subject fibers; at least a part of the subject fibers containing a chelate forming fiber having a chelate formable functional group being capable of forming a chelate with a metal ion. The alkaline battery includes a positive electrode, a negative electrode, the above-described separator placed therebetween, and an electrolyte.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: October 29, 2019
    Assignee: KURARAY CO., LTD.
    Inventors: Tomohiro Hayakawa, Hiroyuki Kawai
  • Patent number: 10446820
    Abstract: An alkaline battery separator having alkali-resistant fibers, beaten cellulose fibers and a binder, wherein an overall freeness, in terms of CSF, is at least 700 ml and at most 765 ml; weight ratios of the alkali-resistant fibers and the beaten cellulose fibers are 28:72 to 72:28; the beaten cellulose fibers comprise mercerized natural wood fibers having a freeness, in terms of CSF, of at least 150 ml and less than 550 ml; and at least a portion of the alkali-resistant fibers is polyvinyl alcohol-based fibers.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: October 15, 2019
    Assignee: KURARAY CO., LTD.
    Inventors: Tomohiro Hayakawa, Toshimichi Kusunoki, Hiroyuki Kawai, Koichi Kambe
  • Publication number: 20180313037
    Abstract: Provided is a dispersant for carbon fibers which allows uniform dispersion of relatively long carbon fibers, e.g., carbon fibers with a length of 12.5 mm or more, particularly 10.0-100.0 mm, more particularly 12.5-50.0 mm in an aqueous medium. A dispersant for carbon fibers used by combining: (A) a random copolymer of phenylglycidyl ether and ethylene oxide, or a random copolymer of phenylglycidyl ether, ethylene oxide and propylene oxide; and (B) a polyether-based polyurethane resin based on a bifunctional polyol and hexamethylene diisocyanate, the bifunctional polyol being polyethylene glycol and/or an ethylene oxide-propylene oxide random copolymer.
    Type: Application
    Filed: September 27, 2016
    Publication date: November 1, 2018
    Applicant: KURARAY CO., LTD.
    Inventors: Tomohiro HAYAKAWA, Toshimichi KUSUNOKI, Hiroyuki KAWAI, Hideo KIYOYAMA
  • Patent number: 10106923
    Abstract: Provided is an extra-fine fiber sheet including an extra-fine fiber assembly including extra-fine fibers having an average fiber diameter of 500 nm or smaller. The extra-fine fiber sheet includes an extra-fine fiber assembly. The assembly includes a solvent-spinnable polymer (A) having a weight average molecular weight of 5,000 to 100,000 as a main component and a polymer (B) having a weight average molecular weight equal to or more than 10 times as large as that of the polymer (A) as an accessory component; and the assembly includes constituent fibers having an average fiber diameter of 10 to 500 nm. The polymer (A) may be a non-conductive polymer, and the polymer (B) may be a thickening polymer.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: October 23, 2018
    Assignee: KURARAY CO., LTD.
    Inventors: Takayoshi Hosoya, Tomohiro Hayakawa, Hiroyuki Kawai, Hideo Hayashi
  • Publication number: 20180269450
    Abstract: The present invention relates to an alkaline battery separator comprising alkali-resistant fibers, beaten cellulose fibers, and a binder, wherein 1) an overall freeness, in terms of CSF, is at least 700 ml, wherein 2) weight ratios of the alkali-resistant fibers and the beaten cellulose fibers are 28:72 to 72:28, and wherein 3) the beaten cellulose fibers comprise mercerized natural wood fibers having a freeness, in terms of CSF, of at least 150 ml and less than 550 ml.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 20, 2018
    Applicant: KURARAY CO., LTD.
    Inventors: Tomohiro HAYAKAWA, Toshimichi KUSUNOKI, Hiroyuki KAWAI, Koichi KAMBE
  • Patent number: 10020124
    Abstract: A separator for electric double layer capacitor comprising a fiber sheet containing 10% by mass (relative to 100% by mass of fiber sheet) of polyvinyl alcohol fibers (fibers A) having a hot water-dissolving temperature of lower than 100° C. and higher than 85° C., the separator having a density within a range of 0.25 to 0.7 g/cm3, and a thickness within a range of not less than 5 ?m and less than 40 ?m.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: July 10, 2018
    Assignee: KURARAY CO., LTD.
    Inventors: Tomohiro Hayakawa, Hiroyuki Kawai, Hideo Hayashi