Abstract: Erroneous detection of a failure in spite of the absence of failure on the route on account of a communication delay is to be prevented. A node device detects a failure on the route to a remote node device is detected by a failure to receive a packet from the remote node device after the elapse of a determined detection time. The node device sets “remote system transmission interval×detection multiplier” to be a first detecting time on the basis of a packet transmission interval determined by negotiation with the remote node device. It also sets the sum of “remote system actual transmission interval ×detection multiplier” and “tolerable delay time” to be a second detecting time. The first detecting time and the second detecting time are compared, and what is longer is determined as the detecting time to be applied to actual operation.

Abstract: An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.

Abstract: Embodiments in accordance with the present invention relate to detecting a micro-relief that exists on surfaces of a magnetic disk. A phase or frequency of a read signal obtained when data written to a minute projection or a minute concavity on a recording surface of a magnetic disk is read out, differs from that of a read signal obtained when data written to a flat recording surface is read out. The phase progresses in the minute projection, whereas the phase is delayed in the minute concavity. A micro-relief is detected by measuring a deviation value of this frequency, and then defect registration is performed. Embodiments in accordance with the present invention are configured to detect a minute projection whose level does not cause TA. Embodiments in accordance with the present invention may also be configured to provide a highly reliable magnetic disk drive by controlling the flying height in response to a state of a minute projection and that of a minute concavity.

Abstract: The specification relates to a method for producing a chimeric non-human animal, which comprises preparing a microcell containing a foreign chromosome(s) or a fragment(s) thereof and transferring the foreign chromosome(s) or fragment(s) thereof into a pluripotent cell by fusion with the microcell; a chimeric non-human animal which can be produced by the above method and its progeny; tissues and cells derived therefrom; and a method for using the same. Further, a pluripotent cell containing a foreign chromosome(s) or a fragment(s) thereof, a method for producing the same, and a method for using the same are also provided. Moreover, a pluripotent cell in which at least two endogenous genes are disrupted, and a method for producing the same by homologous recombination are provided.

Abstract: Embodiments of the invention provide a magnetic disk drive capable of reducing an area used for a preamble of each data sector to increase the storage capacity. The magnetic disk drive adopts a data-surface servo system. In one embodiment, main preambles are written on a magnetic disk at a frequency of a data clock. Each of data sectors is written with a write clock that is synchronized with a signal obtained by reading the main preamble. The data sectors include sub preambles respectively. When the data sector which has been written in this manner is read, a read clock is synchronized by use of a signal obtained by reading the main preamble, and a signal obtained by reading the sub preamble included in a data sector to be read. The bit length of the sub preamble is shorter than that of the conventional preamble that is used to independently achieve the synchronization.

Abstract: Embodiments of the invention provide a magnetic disk drive and its control method capable of effectively using the unrecordable area which is caused due to the composite magnetic head's gap between the read head and the write head. In one embodiment, a disk drive comprises a composite magnetic head structured in such a manner that during write the write head WH reaches each servo area earlier than the read head RH, and a read write control unit to control the write and read done by the composite magnetic head. On the disk, common servo data SP to be used both during read and during write, write servo data SW to be used during write and read servo data SR to be used during read are recorded in this order in each servo area. During write, the read write control unit starts the write head recording data at the timing when reading write servo data SW from the servo area is completed.

Abstract: To provide an antibody against FGF23 and a pharmaceutical composition such as a preventive or therapeutic agent which can prevent or treat by suppressing an action of FGF23 by using the antibody. An antibody or its functional fragment against human FGF23 produced by hybridoma C10 (Accession No. FERM BP-10772).

Abstract: An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

Abstract: An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

Abstract: An image processing apparatus is connected to a specific network for processing an image according to image information input to the image processing apparatus. The image processing apparatus includes an apparatus information storage unit for storing apparatus information of other apparatus connected to the network; an inquiry unit for inquiring an operational state of the other apparatus according to the apparatus information stored in the apparatus information storage unit; a determining unit for determining the operational state of the other apparatus according to an inquiry result of the inquiry unit; and a switching control unit for switching an operational state of the image processing apparatus between an active state and a power save state according to a number of apparatus that the determining unit determines as being in the active state.

Abstract: According to one embodiment, an information reproducing device comprises a file creation module creating an application file, a decision module deciding whether a reading of the application is completed at a specified playback end time of the video object, a comparator module comparing in size between non-played back portion of the video object and the stored application file, a playback continuing module playing back the non-played back portion when it is smaller in size, and a readout module reading the stored application file when it is smaller in size.

Abstract: Even when all of usable sessions are in use, a communication can be established for a new session and the interrupted session is automatically restored. Information on degrees of importance of communication sessions and information of restoration requirement are set in advance and stored in a session importance table in association with identifier (URI) of communication initiating terminals and identifier of destinations of communication. When a connection request for a session having a high degree of importance such as an emergency session is received, the session having the lowest degree of importance is selected and interrupted. Information of the interrupted session such as the communication initiator identifier and the communication destination identifier is stored in a session restoration table.

Abstract: The present invention relates to a human artificial chromosome which is genetically transmissible to the next generation with high efficiency and the method for using the same. More specifically, the present invention relates to: a human artificial chromosome in which an about 3.5 Mb to about 1 Mb region containing an antibody ? light chain gene derived from human chromosome 22 is bound to a chromosome fragment which is transmissible to a progeny through a germ line of a non-human animal, said chromosome fragment is derived from another human chromosome; a non-human animal carrying the human artificial chromosome and an offspring thereof; a method for producing the non-human animal; a method for producing a human antibody using the non-human animal or an offspring thereof; and a human antibody-producing mouse carrying the human artificial chromosome.

Abstract: The present invention relates to a method for producing a modified foreign chromosome(s) or a fragment(s) thereof, which comprises the steps of: (a) preparing a microcell comprising a foreign chromosome(s) or a fragment(s) thereof, and transferring said foreign chromosome(s) or a fragment(s) into a cell with high homologous recombination efficiency through its fusion with said microcell; (b) in said cell with high homologous recombination efficiency, inserting a targeting vector by homologous recombination into a desired site of said foreign chromosome(s) or a fragment(s) thereof, and/or a desired site of a chromosome(s) derived from said cell with high homologous recombination efficiency, thereby marking said desired site; and (c) in said cell with high homologous recombination efficiency, causing deletion and/or translocation to occur at the marked site of said foreign chromosome(s) or a fragment(s) thereof.

Abstract: The present invention relates to a human artificial chromosome which is genetically transmissible to the next generation with high efficiency and the method for using the same. More specifically, the present invention relates to: a human artificial chromosome in which an about 3.5 Mb to about 1 Mb region containing an antibody ? light chain gene derived from human chromosome 22 is bound to a chromosome fragment which is transmissible to a progeny through a germ line of a non-human animal, said chromosome fragment is derived from another human chromosome; a non-human animal carrying the human artificial chromosome and an offspring thereof; a method for producing the non-human animal; a method for producing a human antibody using the nonhuman animal or an offspring thereof; and a human antibody-producing mouse carrying the human artificial chromosome.

Abstract: According to one embodiment, an information reproducing apparatus includes a memory, a decoder, an intermediate memory which is disposed between the memory and the decoder and which temporarily stores, in succession, the data that are supplied from the memory and then outputs the data to the decoder, switching circuit for switching an output of the memory to one of the decoder and the intermediate memory, memory management circuit for managing arrangement information of the data that are stored in the memory, determination circuit for determining whether the data that are stored in the memory are arranged in physically discontinuous memory areas of the memory, and switching control circuit for switching, in a case where the determination circuit determines that the data are arranged in the physically divided memory areas, the switching circuit in a manner to input the data output from the memory to the decoder via the intermediate memory.

Abstract: A camera having a lens barrel housed therein includes a reflection optical member for reflecting a light beam incident along a first optical axis (O1) from a subject so as to reflect the light beam toward a second optical axis (O2) intersecting the first optical axis; a light-quantity adjusting member for adjusting the quantity of incident light from the subject; and a drive source for displacing the light-quantity adjusting member, in which by displacing the light-quantity adjusting member, the quantity of the incident light from the subject can be adjusted, and the light-quantity adjusting member is displaced in a direction substantially perpendicular to an optical axial plane inclusive of the first optical axis and the second optical axis so as to adjust the light-quantity.

Abstract: A failure detection protocol is applied so that failure detection requests for the same aggregated link can be processed even when the failure detection requests differ among routing protocols. The failure detection protocol is executed for each of the physical links that form an aggregated link, and a notification is sent to a higher-level application (for example, a routing protocol), which is a requesting source of a communication line failure monitoring request, with a discrimination between a case in which the communication of the aggregated link in its entirety fails and a case in which some physical links of the aggregated link fail.

Abstract: The present invention provides an electrocasting method by which the shape of the surface opposite to the surface to be electrodeposited on the mold can be controlled. A molded metal article is electrocast by forming an insulating layer on the side wall faces of a cavity and the outer wall face of a conductive mold in which the cavity is formed, placing the mold in an electrolysis tank and applying voltage, electrodepositing metal on the bottom face of the cavity, and growing the metal layer in the cavity so as to leave a space having a height of at least one-third the width of the cavity.