Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: A control valve of a multi-supercharger system is provided. The control valve includes a first spool rotatably fitted in a valve body and a second spool fitted in the valve body to be coaxially rotatable together with the first spool. A disk member is installed in the valve body to partition a first chamber, in which the first spool is disposed, and a second chamber, in which the second spool is disposed, from each other. A portion of the disk member includes a communication sector, through which the first chamber and the second chamber communicate with each other. A first inlet and a first outlet are disposed in the valve body and a second inlet and a second outlet are disposed in the valve body. A first valve aperture is formed in the first spool for allowing the first spool to communicate with the communication sector.

Abstract: A column control circuit may include a column control signal generation circuit and a column access block signal generation circuit. The column control signal generation circuit is configured to activate an input/output strobe signal when a column access block signal is deactivated. The column control signal generation circuit is configured to deactivate the input/output strobe signal when the column access block signal is activated. The column access block signal generation circuit is configured to activate the column access block signal when gap-less read commands may be inputted. The column access block signal generation circuit may deactivate the column access block signal during a period corresponding to an N-th read command among the gap-less read commands. N is an integer that is no less than 2.

Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Abstract: A transistor heat dissipation module is adapted for at least one transistor. The transistor heat dissipation module includes a heat dissipation member and an elastic member. The heat dissipation member includes a first wall and a second wall opposite to each other and a first connecting member connected to the first wall and the second wall. An accommodating space is formed between the first wall and the second wall. The transistor is disposed in the accommodating space. The elastic member is disposed in the accommodating space and is located between the at least one transistor and the first wall to press the at least one transistor against the second wall. An assembly method of a transistor heat dissipation module is further provided.

Abstract: An exhaust manifold may include first to fourth exhaust pipes respectively connected to first to fourth cylinders which is sequentially disposed in an engine, the exhaust manifold may include a first exhaust manifold including the second exhaust pipe connected to the second cylinder and the third exhaust pipe connected to the third cylinder; a second exhaust manifold including the first exhaust pipe connected to the first cylinder, the fourth exhaust pipe connected to the fourth cylinder and the first exhaust pipe, and a recirculation valve apparatus mounted in the first exhaust pipe; wherein the second exhaust pipe and the third exhaust pipe are directly connected to a converter housing for mounting a catalytic converter in which purifies exhaust gas, and wherein the fourth exhaust pipe is connected to the first exhaust pipe at upstream of the recirculation valve, and the first exhaust pipe is directly connected to the converter housing.

Abstract: A column control circuit may include a column control signal generation circuit and a column access block signal generation circuit. The column control signal generation circuit is configured to activate an input/output strobe signal when a column access block signal is deactivated. The column control signal generation circuit is configured to deactivate the input/output strobe signal when the column access block signal is activated. The column access block signal generation circuit is configured to activate the column access block signal when gap-less read commands may be inputted. The column access block signal generation circuit may deactivate the column access block signal during a period corresponding to an N-th read command among the gap-less read commands. N is an integer that is no less than 2.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Abstract: An engine may include an engine including combustion chambers, an intake line connected to the plurality of combustion chambers and through which outside air supplied to the combustion chamber flows, an intake manifold connected to an intake side of the combustion chamber, an exhaust manifold connected to an exhaust side of the combustion chamber, an exhaust line connected to the exhaust manifold, a turbocharger including a compressor mounted in the intake line, and a turbine rotating in association with the compressor and connected to the exhaust manifold and the exhaust line, a wastegate passage bypassing the turbine from the exhaust manifold, an electric supercharger connected to the compressor of the turbocharger by the intake line, a power device electrically-connected to the electric supercharger and configured for supplying electric power to the electric supercharger or absorbing and storing electric power generated by the electric supercharger, and a controller for controlling the operation of the pow

Abstract: Disclosed herein are heteroduplex nucleic acid molecules, heteroduplex nucleic acid conjugates, and pharmaceutical compositions for modulating a protein expression. Also described herein include methods of treating a disease or indication which utilize a heteroduplex nucleic acid molecule, a heteroduplex nucleic acid conjugate, or a pharmaceutical composition that comprises a heteroduplex nucleic acid molecule.

Abstract: An engine system may include: an engine including cylinders that generate a driving torque by combusting fuel; a first intake manifold connected to an intake line through which flows intake air into some of the plurality of cylinders; a second intake manifold supplying the intake air to the other cylinders of the plurality of cylinders through the first intake manifold; a first exhaust manifold connected to some cylinders that are connected to the first intake manifold; a second exhaust manifold connected to some other cylinders that are connected to the second intake manifold; a recirculation line branched from the second exhaust manifold to be coupled to the second intake manifold; a recirculation inlet valve disposed at a point at which the recirculation line and the second exhaust manifold are joined; and a manifold connection valve disposed on an intake line between the first intake manifold and the second intake manifold.

Abstract: A column control circuit may include a column control signal generation circuit and a column access block signal generation circuit. The column control signal generation circuit is configured to activate an input/output strobe signal when a column access block signal is deactivated. The column control signal generation circuit is configured to deactivate the input/output strobe signal when the column access block signal is activated. The column access block signal generation circuit is configured to activate the column access block signal when gap-less read commands may be inputted. The column access block signal generation circuit may deactivate the column access block signal during a period corresponding to an N-th read command among the gap-less read commands. N is an integer that is no less than 2.

Abstract: A control valve of a multi-supercharger system is provided. The control valve includes a first spool rotatably fitted in a valve body and a second spool fitted in the valve body to be coaxially rotatable together with the first spool. A disk member is installed in the valve body to partition a first chamber, in which the first spool is disposed, and a second chamber, in which the second spool is disposed, from each other. A portion of the disk member includes a communication sector, through which the first chamber and the second chamber communicate with each other. A first inlet and a first outlet are disposed in the valve body and a second inlet and a second outlet are disposed in the valve body. A first valve aperture is formed in the first spool for allowing the first spool to communicate with the communication sector.

Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.

Abstract: An engine system may include: an engine including cylinders that generate a driving torque by combusting fuel; a first intake manifold connected to an intake line through which flows intake air into some of the plurality of cylinders; a second intake manifold supplying the intake air to the other cylinders of the plurality of cylinders through the first intake manifold; a first exhaust manifold connected to some cylinders that are connected to the first intake manifold; a second exhaust manifold connected to some other cylinders that are connected to the second intake manifold; a recirculation line branched from the second exhaust manifold to be coupled to the second intake manifold; a recirculation inlet valve disposed at a point at which the recirculation line and the second exhaust manifold are joined; and a manifold connection valve disposed on an intake line between the first intake manifold and the second intake manifold.