Abstract: A fuel cell stack arrangement includes a fuel cells arranged between a first and a second end plate. At least one of the end plates is designed as a channel end plate with at least one channel. The channel has a stack opening, which is opened in the direction of the stack, and a second opening. The stack opening and the second opening are connected to each other via a channel section and are arranged at a distance to each other in a top view looking down on the channel end plate.

Abstract: A cobalt coincidence radioactivity detector is used to separate radioactive concrete dust from uncontaminated dust resulting from dismantling a nuclear power plant. A suction air stream carries the dust through a vacuum line to a cyclone segregator. The dust falls into a smaller first container from the segregator, and the detector detects radioactivity in the filled first container. The dust is transferred from the first container to a second container if the detected radioactivity exceeds a predetermined threshold. The dust is transferred from the first container to a third container if the detected radioactivity does not exceed the predetermined threshold. A filter collects the dust carried past the segregator by the suction air stream. If the radioactivity detected in the dust that collects on the filter exceeds the predetermined threshold, the dust in the first container is transferred to the second container before the first container is allowed to fill.

Abstract: A fuel cell stack is formed from a plurality of stacked fuel cell units and at least one stack end element. The stacked fuel cell units being surrounded by a housing. A frame element is situated on the at least one stack end element and the housing on the end-face side. At least one seal is situated at least between the stack end element and the housing in the area of the frame element.

Abstract: A fuel cell stack includes a plurality of stacked fuel cell units and at least one stack end element that are clamped a clamping device. The clamped fuel cell units are surrounded by a housing. A circumferential seal, in particular a lip seal, which has recesses for accommodating the clamping device is situated between the housing and the at least one stack end element. The clamping device is electrically insulated at least in the area of the recesses.

Abstract: In a first aspect, the present invention relates to a method of determining assembly, homogeneity and/or thermodynamic stability of biological macromolecular complexes. In particular, the method allows determining maximum stability of said complexes based on fluorescence changes at an appropriate wavelength as a function of temperature whereby said fluorescence changes reflect the status of assembly, homogeneity and/or thermodynamic stability of the biological macromolecular complexes. Said method is based on identifying two state and multistate unfolding fluorescence curves as a function of temperature by fitting said curves according to a multistate unfolding model. In addition, a computer program and a computer program storage medium as well as an apparatus and a system is provided for determining the assembly, homogeneity and/or thermodynamic stability of biological macromolecular complexes.

Abstract: The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof of as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases.

Abstract: A compound of formal (I) is described: wherein R1 and R2 are as defined in the text and wherein the compounds are intended for use in treating medical conditions characterized by an imbalance in dopamine receptor activity.

Abstract: A device used to provide hot exhaust gases for driving a turbine. The device includes a burner, the combustion zone of which is directly mounted on or integrated into the gas inlet (turbine housing) of the turbine. The burner is supplied with at least one combustible gas or gas mixture. The combustion zone includes a porous material with a large specific surface area.

Abstract: A method is provided for the treatment of sleep apnea and other conditions wherein an effective amount of crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride of formula (I): optionally comprising water up to 6%, and having an X-ray diffractogram that comprises characteristic peaks (2?) at 11.2°, 19.9°, 20.7° and 34.1°±0.2° is administered to a patient in need thereof.

Abstract: A method is provided for the treatment of sleep apnea and other conditions wherein an effective amount of crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride of formula (I): optionally comprising water up to 6%, and having an X-ray diffractogram that comprises characteristic peaks (2?) at 11.2°, 19.9°, 20.7° and 34.1°±0.2° is administered to a patient in need thereof.

Abstract: A piezoelectric actuator for flowing-around media, with a piezo element arranged between two end caps. The piezo element is surrounded by a ring-shaped sheathing connected to the end caps. The sheathing consists, at least in portions, of a composite material with at least two layers, at least one layer consisting of a metallic material and at least one layer consisting of a polymer.

Abstract: The invention relates to new crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride, the respective manufacture and methods of use, and compositions containing such a compound.

Abstract: Use of a compound of formula (A), wherein: W is a residue which imparts antagonistic and/or agonistic activity at histamine H3-receptors when attached to an imidazole ring in 4(5) position; R1 and R2 may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined for preparing medicaments acting as antagonists and/or agonists at the H3-receptors of histamine.

Abstract: A method for manufacturing a lightweight valve is provided. The lightweight valve includes a valve stem, a hollow valve cone and a valve disk closing the valve cone, the valve stem being provided with a hollow space at an end facing the valve disk, the valve disk also having a force transmission element extending through the hollow valve cone into the stem hollow space. The method includes producing a first one-piece component forming the valve disk with the force transmission element by casting, forming and/or a powder metallurgy method, producing a second component forming the valve stem and the valve cone and joining the first and second components together and connecting them by a material, non-positive and/or positive connection.

Abstract: Use of a compound of formula (A), wherein: W is a residue which imparts antagonistic and/or agonistic activity at histamine H3-receptors when attached to an imidazole ring in 4(5) position; R1 and R2 may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined for preparing medicaments acting as antagonists and/or agonists at the H3-receptors of histamine.

Abstract: A lightweight valve (1), in particular for internal combustion engines, and a method for manufacturing the lightweight valve (1) are provided. The valve comprises a valve stem (3), a hollow valve cone (7) and a valve disk (13), the valve cone (7) and the valve disk (13) together forming a hollow space. The valve disk (13) is provided with a gripping receiver (23) for the valve stem (3).

Abstract: A compound of formal (I) is described: wherein R1 and R2 are as defined in the text and wherein the compounds are intended for use in treating medical conditions characterized by an imbalance in dopamine receptor activity.

Abstract: A lightweight valve (1), in particular for internal combustion engines, is provided, with a valve stem (3), with a hollow valve cone (5) and with a valve disk (7) closing the valve cone hollow space on one side, a valve cone support being provided in the hollow space. The valve cone support is provided at a distance from the valve disk (7).

Abstract: A piezoelectric actuator for flowing-around media, with a piezo element arranged between two end caps. The piezo element is surrounded by a ring-shaped sheathing connected to the end caps. The sheathing consists, at least in portions, of a composite material with at least two layers, at least one layer consisting of a metallic material and at least one layer consisting of a polymer.

Abstract: A multipart composite valve for an internal combustion engine, in which a valve shaft (2) and a valve plate (4) are embodied separately while being joined together in an overlapping area (6). The invention is characterized in that at least some parts of the valve shaft (2) are provided with an intermediate layer (8) in the overlapping area (6). Said intermediate layer (8) forms an integral joint with both the valve shaft (2) and the valve plate (4) in the form of a chemical bond, the valve plate (4) being cast onto the valve shaft (2).