Patents by Inventor Holtzman

Holtzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220408677
    Abstract: Novel maize varieties that produce kernels with high levels of carotene and an aerial root mucilage, including the maize variety designated GenetecOne, and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprising crossing maize variety GenetecOne with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into GenetecOne through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided.
    Type: Application
    Filed: June 29, 2021
    Publication date: December 29, 2022
    Inventor: Jon Evan Holtzman
  • Publication number: 20220411485
    Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.
    Type: Application
    Filed: August 24, 2021
    Publication date: December 29, 2022
    Inventors: David Holtzman, Hong Jiang, Fan Liao, Thu Nga Bien-Ly, Mark S. Dennis, Jing Guo, Adam P. Silverman, Ryan J. Watts, Yin Zhang
  • Publication number: 20220403567
    Abstract: A volumetric weaving approach employs a vertical aspect of woven warp and weft fibers to generate volumetric structures through formation of tie-downs. Tie downs define warp and weft fibers that take a vertical path or component extending perpendicular to a weave plane. Independently controlled heddles provide selective warp fibers control, and a two-dimensional creel that dispenses the warp fibers at differing feed rates allows manipulation of the fibers into three dimensional structures or portions. As a shuttle draws the weft fiber, different layers are raised and lowered to lend a vertical axis to the resulting volumetric structure. Interconnections between the portions include the use of the tie downs to connect multiple portions to define 3-dimensional panels of a finished article such as a shoe. A single pass defining all the interconnected portions of the shoe generates the fully formed shoe without subsequent cutting and seaming of different textile panels.
    Type: Application
    Filed: May 31, 2022
    Publication date: December 22, 2022
    Inventors: Claire E. Harvey, Emily K. Holtzman, Brooks W. Hagan
  • Publication number: 20220405273
    Abstract: Described are computer-based methods and apparatuses, including computer program products, comprising the steps of, or structure for, storing a plurality of expert profiles in a database, each of the plurality of expert profiles comprising information associated with a person having knowledge in a particular category, subject or topic; receiving search criteria over a network from a query source; selecting at least one of the plurality of expert profiles comprising information that satisfy the search criteria; and transmitting expert profile data for each of the selected expert profiles to the remote search engine, the expert profile data comprising data that defines a displayable representation of a corresponding expert profile, the expert profile data further comprising data that facilitates a client-initiated, real-time communication session over the network with a person associated with the corresponding expert profile.
    Type: Application
    Filed: June 6, 2022
    Publication date: December 22, 2022
    Applicant: LIVEPERSON, INC.
    Inventors: Matan Barak, Julius Schorzman, Nir Holtzman Ninio, Uri Goldstein
  • Patent number: 11533105
    Abstract: A method is provided for calibrating a terminal device connected to a transmission line containing an impairment. The method includes steps of obtaining a sequence of frequency domain samples for a digital signal transmitted to the terminal device, determining a reflection coefficient from the obtained frequency domain sequence and a reflection signal arising from the impairment, converting the sequence of frequency domain samples and the frequency domain reflection signal into the time domain to generate a complex time domain sample sequence having a real I time component and an imaginary Q time component, correcting the time domain sample sequence into a corrected time sequence having a phase value of the Q component corresponding to a phase value of the I component, calculating a correcting spin coefficient from the corrected time sequence, and calibrating the terminal device with the correcting spin coefficient to mitigate a rotation of the reflection coefficient.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: December 20, 2022
    Assignee: Cable Television Laboratories, Inc.
    Inventors: Thomas Holtzman Williams, Lin Cheng
  • Patent number: 11527856
    Abstract: A charger extension device has a housing having a top side, a left side, a bottom side, a right side, a rear side, and a front side, an USB port on the front side of the housing, and a port on the rear side of the housing. Another charger extension device has a housing having a top side, a left side, a bottom side, a right side, a rear side, and a front side, an USB port on the front side of the housing, a port on the rear side of the housing, and a cable retention assembly on the rear side of the housing.
    Type: Grant
    Filed: August 1, 2021
    Date of Patent: December 13, 2022
    Inventor: John Holtzman
  • Publication number: 20220390362
    Abstract: A method comprising: receiving, as input, a plurality of spectral data samples, wherein each of the spectral data samples represents spectral reflectance from a plant; at a training stage, training a machine learning model on a training set comprising: (i) the spectral data samples, and (ii) labels associated with stomatal conductance in each of the plants; and at an inference stage, applying the machine learning model to a target spectral data sample associated with a target plant, to predict a stomatal conductance value for the target plant.
    Type: Application
    Filed: November 5, 2020
    Publication date: December 8, 2022
    Applicant: MIGAL APPLIED RESEARCH LTD.
    Inventors: Oded LIRAN, Lilach HOLTZMAN
  • Publication number: 20220354833
    Abstract: The invention relates to treatments for organ rejection, in particular to treatments for lung transplant associated bronchiolitis obliterans syndrome by administering a neutrophil elastase inhibitor, such as alvelestat. The invention also relates to treatments for graft versus host disease.
    Type: Application
    Filed: September 17, 2020
    Publication date: November 10, 2022
    Applicants: MEREO BIOPHARMA 4 LIMITED, DUKE UNIVERSITY, NATIONAL CANCER INSTITUTE
    Inventors: Jacqueline PARKIN, Anthony SUNG, Steven Z. PAVLETIC, Annie IM, Noa G. HOLTZMAN, Cody J. PEER
  • Patent number: 11482215
    Abstract: A method comprising detecting an activation of an intelligent assistant on an electronic device, waking up the intelligent assistant from a sleep mode in response to the activation, and determining an amount of vocabulary the intelligent assistant acts upon during a listening mode based on a type of the activation.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: October 25, 2022
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jeffrey C. Olson, Henry N. Holtzman, Jean-David Hsu, Jeffrey A. Morgan
  • Patent number: 11451020
    Abstract: Generating an assessment of the suitability of cables, ducts, tubes, pipes and/or other hollow-type of conduits to extraction of cores, conductors, insulation, etc. included therein while still buried in the ground or otherwise positioned out-of-sight so as to be unavailable for visual and/or physical inspection is contemplated. The assessment may be used to indicate a suitability of a cable buried in the ground of a hybrid fiber coaxial (HFC) cable plant to extraction of the type whereby a core of the cable may be extracted using hydraulics while still buried.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: September 20, 2022
    Assignee: Cable Television Laboratories, Inc.
    Inventors: Luis Alberto Campos, Thomas Holtzman Williams, Zhensheng Jia
  • Publication number: 20220284585
    Abstract: A computer-implemented method for tumor segmentation, the method comprises obtaining image data of a region of interest of a subject's body, wherein the region of interest corresponds to a tumor of the subject's body, generating two or more tumor segmentation predictions based on the image data, calculating a divergence between the two or more tumor segmentation predictions, and generating a visualization of tumor segmentation uncertainty based on the calculated divergence between the two or more tumor segmentation predictions.
    Type: Application
    Filed: March 1, 2022
    Publication date: September 8, 2022
    Applicant: Novocure GmbH
    Inventors: Michal HOLTZMAN GAZIT, Reuven Ruby SHAMIR
  • Patent number: 11428441
    Abstract: A geothermal heat mining system can operate within a single primary borehole in a geothermal reservoir. A primary fluid loop can include a cold working fluid line leading into the primary borehole and a hot working fluid line coming out of the primary borehole. A secondary fluid loop can be located down the primary borehole, where the secondary fluid loop is in thermal contact with the geothermal reservoir and is entirely subsurface. A downhole heat mining device can control a rate of heat transfer from the secondary fluid loop to the primary fluid loop by selectively controlling fluid flow through the primary fluid loop, the secondary fluid loop, or both.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: August 30, 2022
    Assignee: Strabo Engineering, LLC
    Inventor: Benjamin Holtzman
  • Publication number: 20220259495
    Abstract: The present invention relates to a method for synthesizing a semiconducting nanosized material.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 18, 2022
    Applicant: Merck Patent GmbH
    Inventors: Inbal DAVIDI, Amir HOLTZMAN, Alex IRZH, David MOCATTA, Elizaveta KOSSOY, Sanaa KHALIL, Denis GLOZMAN
  • Publication number: 20220248827
    Abstract: The present application relates to the design of a class of beauty products that facilitates personalized replenishment. The physical product is a new type of dispenser comprising a pump assembly and a sleeve or housing for containing a replaceable cartridge of a specific type of product, such as a foundation. The cartridge is an air-less cartridge that may be releasably secured to the dispenser or pump assembly such that a user may remove the cartridge from the dispenser or pump and replace the cartridge with another cartridge containing the same or a different product.
    Type: Application
    Filed: November 15, 2021
    Publication date: August 11, 2022
    Applicant: IM Pro Makeup NY LP
    Inventors: Oran Holtzman, Maayan Gianella
  • Publication number: 20220253929
    Abstract: The field of the invention relates to systems and methods for creating on-line transactional statements, and more particularly to creating electronic transactional statements that can responsively and dynamically fit any display window size. In an embodiment, a responsive transactional statement generation system having one or more processors and a non-transitory computer-readable medium containing program instructions that cause said one or more processors to receive data files each includes data representing one or more transactional statements, parse the received data files using one or more predetermined schemas to create restructured electronic transactional statements, save the restructured electronic transactional statements and display the restructured electronic transactional statements responsively at a user device.
    Type: Application
    Filed: February 24, 2022
    Publication date: August 11, 2022
    Inventors: Paul A. Holtzman, Darren M. Holtzman, Todd J. Holtzman, Marcos Jurgensen, Edwin G. Gil, Michael A. Tarr, Wade A. Hought, Olga Lavtar, Julian Renteria, Flavio A. dos Santos, Michael W. Armstrong, Stacey Taylor
  • Patent number: 11407771
    Abstract: Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: August 9, 2022
    Assignee: Washington University
    Inventors: Michael J. Holtzman, Arthur G. Romero, Benjamin J. Gerovac, Zhenfu Han, Shamus P. Keeler, Kangyun Wu
  • Publication number: 20220239537
    Abstract: A method for transmitting a digital frame by an optical network unit in a digital communications network includes steps of arranging received data into a series of symbols, installing a primary cyclic prefix immediately preceding the series of symbols in time, and inserting individual ones of a plurality of secondary cyclic prefixes between each adjacent pair of symbols in the series of symbols. A length of each secondary cyclic prefix corresponds to a first duration shorter than an amount of time needed to turn on a laser of the optical network unit. The method further includes a step of providing to the optical network unit the digital frame. The digital frame includes the primary cyclic prefix, the plurality of secondary cyclic prefixes, and the series of symbols. The method further includes a step of modulating the provided digital frame by a laser of the optical network unit.
    Type: Application
    Filed: April 11, 2022
    Publication date: July 28, 2022
    Inventors: Douglas D. Jones, Luis Alberto Campos, Thomas Holtzman Williams
  • Publication number: 20220235612
    Abstract: A spallation drill head can include a drill head body having a primary face substantially oriented facing in a primary drilling direction along a longitudinal axis of the drill head body. A liquid inlet can be on the drill head body. The liquid inlet can be connected or connectable to a liquid supply line. An internal liquid connection can be oriented within the drill head body and fluidly connected to the liquid inlet. A plurality of liquid jets can be oriented on the primary face of the drill head. The liquid jets can be fed by the liquid inlet through the internal liquid connection. A mass flow controller can be associated with the liquid jets to control delivery of liquid by the liquid jet, and flowrates to at least two of the liquid jets can be independently controllable.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 28, 2022
    Inventor: Benjamin Holtzman
  • Publication number: 20220218358
    Abstract: An embolization microcatheter for delivery of embolization beads to a target area, the microcatheter including a proximal end and a distal end, the distal end terminating in an end opening sized and shaped to allow delivery of a suspension of embolization beads, and a filter section located between in proximity to the distal end opening; the filter section including a large plurality of openings distributed circumferentially around a wall thereof, the filter section configured to allow outflow of the suspension fluid while preventing outflow of the embolization beads.
    Type: Application
    Filed: May 27, 2020
    Publication date: July 14, 2022
    Inventors: Tom DAGAN, Nir HOLTZMAN, Yuval ZIPORY, Osnat HARBATER, Eran MILLER
  • Patent number: 11386106
    Abstract: Described are computer-based methods and apparatuses, including computer program products, comprising the steps of, or structure for, storing a plurality of expert profiles in a database, each of the plurality of expert profiles comprising information associated with a person having knowledge in a particular category, subject or topic; receiving search criteria over a network from a query source; selecting at least one of the plurality of expert profiles comprising information that satisfy the search criteria; and transmitting expert profile data for each of the selected expert profiles to the remote search engine, the expert profile data comprising data that defines a displayable representation of a corresponding expert profile, the expert profile data further comprising data that facilitates a client-initiated, real-time communication session over the network with a person associated with the corresponding expert profile.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: July 12, 2022
    Assignee: LIVEPERSON, INC.
    Inventors: Matan Barak, Julius Schorzman, Nir Holtzman Ninio, Uri Goldstein