Abstract: Example methods and systems provide a workplace assistant application that can detect electronic content associated with a remote user and access multiple communication channels connected to a workplace assistant client application. The system can submit the electronic content to one or more predictive models to provide a context for the electronic content. The context is based at least in part on information from multiple channels. The system can generate, using the predictive model(s), an action item based at least in part on the context of the electronic content as well as display or store the action item using the workplace assistant client application. An action item, as examples, can be a “to do” item, a meeting agenda, a reminder, a meeting, a task, or some combination of one or more of these.

Abstract: An Enhanced Lift Assist Device is described. The device allows a user to lift and manipulate large, heavy or bulky items by applying force to the item as opposed to traditional control methods such as buttons. This force based system provides ease of movement of the item, making it appear much lighter than it actually is. The Enhanced Lift Assist Device also includes an adjustable base that allows for change of orientation of the device that may include leveling or self-leveling functionality, allowing the device to be operated in non-traditional environments that require leveling or operational adjustments for proper functioning.

Abstract: Provided herein are methods for the treatment of bladder cancer.

Abstract: A platform assembly for a lift device includes a floor structure, a rail coupled to the floor structure and extending upward from the floor structure, a control panel coupled to the rail, a barrier having a first end coupled to the rail and a second end opposite the first end, and a sensor. The first end of the barrier is configured to detach from the rail in response to a trip force being applied to the barrier. The sensor is configured to provide a trip indication in response to the first end of the barrier being detached from the rail.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: A work platform for a personnel lift includes a floor structure, a safety rail coupled with the floor structure and defining a personnel work area, and a control panel area. A protection envelope surrounds the control panel area and enhances protection for an operator from an obstruction or structure that may constitute a crushing hazard. In one arrangement, the protection envelope includes protection bars on either side of the control panel area extending above the safety rail relative to the floor structure. In another arrangement, the protection envelope includes a platform barrier that is configured to trip upon an application of a predetermined force.

Abstract: A pressure-driven solar photovoltaic panel automatic tracking device includes a photovoltaic panel, a rotating shaft, a rotating wheel, a transmission component, a first counterweight, a second counterweight, a bellow tube, and a gas supply mechanism; the photovoltaic panel is fixed to the rotating shaft, the rotating wheel is fixed to the rotating shaft, the rotating wheel is provided with the transmission component, and both ends of the transmission component are respectively connected to the first counterweight and the second counterweight; the first counterweight is connected to the bellow tube, and the bellow tube is connected to the gas supply mechanism; and the bellow tube is expanded and contracted by controlling the gas supply mechanism, so that the first counterweight moves in the vertical direction, thereby driving the rotating wheel to rotate, so as to realize the automatic tracking of the sunlight by the photovoltaic panel.

Abstract: An analysis method and an electronic apparatus for breast image are provided. The method includes the following steps. One or more breast ultrasound images are obtained. The breast ultrasound images are used for forming a three-dimensional (3D) breast model. A volume of interest (VOI) in the breast ultrasound image is obtained by applying a detection model on the 3D breast model. The VOI is compared with a tissue segmentation result. The VOI is determined as a false positive according to a compared result between the VOI and the tissue segmentation result. The compared result includes that the VOI is located at a glandular tissue based on the tissue segmentation result. In response to the VOI being located in the glandular tissue of the tissue segmentation result, the VOI is compared with the lactiferous duct in the 3D breast model.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: A tubular heat exchanger includes an upper tube plate box, a lower tube plate box, a plurality of heat exchange tubes, and a pressure bolt. Each heat exchange tube includes an inlet end and an outlet end opposite to the inlet end, the inlet end passes through the upper tube plate box, the outlet end passes through the lower tube plate box, the first sealing rubber is filled in a gap between the plurality of heat exchange tubes and the upper tube plate box, and the second sealing rubber is filled in a gap between the plurality of the heat exchange tubes and lower tube plate box. The pressure bolt is located between the upper tube plate box and the lower tube plate box. The present application also relates to a packaging method of the tubular heat exchanger.

Abstract: A tubular heat exchanger includes an upper tube plate box, a lower tube plate box, a plurality of heat exchange tubes, and a pressure bolt. Each heat exchange tube includes an inlet end and an outlet end opposite to the inlet end, the inlet end passes through the upper tube plate box, the outlet end passes through the lower tube plate box, the first sealing rubber is filled in a gap between the plurality of heat exchange tubes and the upper tube plate box, and the second sealing rubber is filled in a gap between the plurality of the heat exchange tubes and lower tube plate box. The pressure bolt is located between the upper tube plate box and the lower tube plate box. The present application also relates to a packaging method of the tubular heat exchanger.

Abstract: An Enhanced Lift Assist Device is described. The device allows a user to lift and manipulate large, heavy or bulky items by applying force to the item as opposed to traditional control methods such as buttons. This force based system provides ease of movement of the item, making it appear much lighter than it actually is. The Enhanced Lift Assist Device also includes an adjustable base that allows for change of orientation of the device that may include leveling or self-leveling functionality, allowing the device to be operated in non-traditional environments that require leveling or operational adjustments for proper functioning.

Abstract: A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-y1)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.

Abstract: A pressure-driven solar photovoltaic panel automatic tracking device includes a photovoltaic panel, a rotating shaft, a rotating wheel, a transmission component, a first counterweight, a second counterweight, a bellow tube, and a gas supply mechanism; the photovoltaic panel is fixed to the rotating shaft, the rotating wheel is fixed to the rotating shaft, the rotating wheel is provided with the transmission component, and both ends of the transmission component are respectively connected to the first counterweight and the second counterweight; the first counterweight is connected to the bellow tube, and the bellow tube is connected to the gas supply mechanism; and the bellow tube is expanded and contracted by controlling he gas supply mechanism, so that the first counterweight moves in the vertical direction, thereby driving the rotating wheel to rotate, so as to realize the automatic tracking of the sunlight by the photovoltaic panel.

Abstract: A tubular heat exchanger includes an upper tube plate box, a lower tube plate box, a plurality of heat exchange tubes, and a pressure bolt. Each heat exchange tube includes an inlet end and an outlet end opposite to the inlet end, the inlet end passes through the upper tube plate box, the outlet end passes through the lower tube plate box, the first sealing rubber is filled in a gap between the plurality of heat exchange tubes and the upper tube plate box, and the second sealing rubber is filled in a gap between the plurality of the heat exchange tubes and lower tube plate box. The pressure bolt is located between the upper tube plate box and the lower tube plate box. The present application also relates to a packaging method of the tubular heat exchanger.

Abstract: Provided herein are compounds useful for the treatment of cancer.

Abstract: An analysis method and an electronic apparatus for breast image are provided. The method includes the following steps. One or more breast ultrasound images are obtained. The breast ultrasound images are used for forming a three-dimensional (3D) breast model. A volume of interest (VOI) in the breast ultrasound image is obtained by applying a detection model on the 3D breast model. The VOI is compared with a tissue segmentation result. The VOI is determined as a false positive according to a compared result between the VOI and the tissue segmentation result. The compared result includes that the VOI is located at a glandular tissue based on the tissue segmentation result. In response to the VOI being located in the glandular tissue of the tissue segmentation result, the VOI is compared with the lactiferous duct in the 3D breast model.

Abstract: Provided herein are methods for the treatment of bladder cancer.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.