Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salt thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: A thermal protection circuit to protect an electronic device from over-heat comprises a temperature sensor, a hysteresis comparator and a switch circuit. The temperature sensor senses internal temperature of the electronic device and output an internal temperature signal with voltage. The hysteresis comparator outputs a power-off signal when the voltage of the internal temperature signal is lower than a low voltage threshold representing an a determined temperature, or outputs a power-on signal when the voltage of the internal temperature signal is higher than a high voltage threshold representing a restarting temperature. The switch circuit stops transmitting power signals to the electronic device in response to the power-off signal, or continues to transmit the power signals to the electronic device in response to the power-on signal.

Abstract: Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

Abstract: A broadband filter filtering noise over a first conductive wire, a second conductive wire, and a third conductive wire includes a differential-mode filtering circuit connected to both the first conductive wire and the second conductive wire and a common-mode filtering circuit connected to both the first conductive wire and the second conductive wire. The differential-mode filtering circuit includes two inductors and two capacitors for filtering differential-mode noise of different frequencies. The common-mode filtering circuit includes two inductors and six capacitors filtering common-mode noise of different frequencies.

Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are amide compounds of formula (I): wherein Ar1, Q, Y and R3-R6 of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and the pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are novel aromatic compounds of the formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.

Abstract: Disclosed compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: The digitally programmable delay circuit to correct timing skew between data and clock is developed. The digitally programmable delay circuit may be built by cascading delay cells. The delay circuit uses delay cells comprising simple digital elements such as inverters and tri-state inverters to eliminate the intrinsic delay and achieves linearity and monotinicity. The delay cell may be used as a building module which is repeatedly used in a serial fashion. The delay range is fully programmable from the delay of one delay cell to infinity if the chip area is available. The delay range can be scaled by adding more delay cells.

Abstract: The present invention is a method and apparatus for implementing a source synchronous interface in a platform using a Generic Source Synchronous Interface (GSSI) infrastructure. The GSSI infrastructure includes the GSSI bit slices and clock management system. The GSSI bit slice includes balanced cells and bit delay elements, and may be placed either within or close to IO buffers. The GSSI clock management system includes strategically placed frame delay elements with automatic on-chip calibration and control to satisfy various clock-data phase relationships. The GSSI methodology shows how different SSIs may be constructed by combining the common GSSI architecture with unique metal layer configurations. The GSSI architecture solves a critical challenge for platform-based design such as RapidChip™ and the like. The GSSI approach introduces a completely new way to implement various SSIs based on a common minimally diffused GSSI bit slice and clock management infrastructure.

Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.