Abstract: Examples described herein relate to a graphics processing unit (GPU) coupled to the memory device, the GPU configured to: execute an instruction thread; determine if a dual directional signal barrier is associated with the instruction thread; and based on clearance of the dual directional signal barrier for a particular signal barrier identifier and a mode of operation, indicate a clearance of the dual directional signal barrier for the mode of operation, wherein the dual directional signal barrier is to provide a single barrier to gate activity of one or more producers based on activity of one or more consumers or gate activity of one or more consumers based on activity of one or more producers.

Abstract: Provided herein are novel compounds, for example, compounds having a Formula (I), or a pharmaceutically acceptable N salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting TYK2, and/or function of IL-12, IL-23 and/or INF-alpha, and/or in treating various associated diseases or disorders.

Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.

Abstract: The embodiment of the present disclosure provides a recovery device for oil spilling on water, a control method thereof, and a recovery vessel. The recovery device includes a casing, a control center, a variable pressure airbag, an oil detector, an isolation layer, a water suction pump, and a drain pipe. The casing is of a hollow structure, the hollow structure is used to accommodate an oil-water mixture and used as a temporary oil collection tank, the upper part of the casing is provided with an oil-water mixture inlet, the bottom of the casing is provided with a drain port, and the side wall of the casting is provided with an oil suction port. The variable pressure airbag is arranged outside the casing, and the variable pressure airbag is configured to adjust buoyancy of the recovery device. The water suction pump is configured to pump out water in the casing and discharge water to a water environment outside the casing through the drain pipe.

Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: The embodiments of the present disclosure provide a detachable anti-vibration sealing protection device for a pipe flange. The protection device includes a casing, wherein left and right end surfaces of the casing have through holes for the pipeline to pass through, and the casing has an accommodation cavity for placing the flange; a first shock absorption assembly for radial shock absorption of the flange; and a second shock absorption assembly which is installed in a one-to-one correspondence with the flange and is configured for axial shock absorption of the corresponding flange. The first shock absorption assembly and the second shock absorption assembly are installed in the accommodation cavity.

Abstract: An apparatus to facilitate hardware enhancements for double precision systolic support is disclosed. The apparatus includes matrix acceleration hardware having double-precision (DP) matrix multiplication circuitry including a multiplier circuits to multiply pairs of input source operands in a DP floating-point format; adders to receive multiplier outputs from the multiplier circuits and accumulate the multiplier outputs in a high precision intermediate format; an accumulator circuit to accumulate adder outputs from the adders with at least one of a third global source operand on a first pass of the DP matrix multiplication circuitry or an intermediate result from the first pass on a second pass of the DP matrix multiplication circuitry, wherein the accumulator circuit to generate an accumulator output in the high precision intermediate format; and a down conversion and rounding circuit to down convert and round an output of the second pass as final result in the DP floating-point format.

Abstract: The present invention provides a composition comprising dendritic cells loaded with hHsp60sp, which dendritic cells are from a subject and have been fixed with paraformaldehyde (PFA). The subject may suffer from an autoimmune disease. Also provided are a method for preparing the composition; recombinant human cells comprising a heterologous gene encoding a fusion protein of HLA-E and hHsp60sp or B7sp, and expressing the fusion protein on the surface of the cells; a method for determining a percentage of maximum inhibition of testing the function of the HLA-E restricted CD8+ Treg cells from a subject, determining whether HLA-E restricted CD8+ Treg cells freshly isolated from a subject are defective, or determining whether defective HLA-E restricted CD8+ Treg cells from a subject are correctable; and a method for correcting defective HLA-E restricted CD8+ Treg cells, treating type 1 diabetes (T1D), or treating multiple sclerosis (MS).

Abstract: This invention discloses a medicinal composition includes a non-coding RNA molecule and an antibody targeting a tumor antigen for preventing and/or treating cancer. This invention uses the synergistic combination of a non-coding RNA molecule or its functional variant or homologue, and an antibody targeting a tumor antigen to prevent and/or treat cancer, thereby providing a novel and effective method in preventing and/or treating various cancers.

Abstract: A memory device includes: a first conductor extending in parallel with a first axis; a first selector material comprising a first portion that extends along a first sidewall of the first conductor; a second selector material comprising a first portion that extends along the first sidewall of the first conductor; a first variable resistive material comprising a portion that extends along the first sidewall of the first conductor; and a second conductor extending in parallel with a second axis substantially perpendicular to the first axis, wherein the first portion of the first selector material, the first portion of the second selector material, and the portion of the first variable resistive material are arranged along a first direction in parallel with a third axis substantially perpendicular to the first axis and second axis.

Abstract: A bearing cage assembly comprises multi-group rollers (2), each group has multiple rollers, and each roller is a barrel roller, multiple rollers are stacked together to form a group of rollers, and the end surfaces of each two adjacent rollers contact with each other. Multiple groups of pockets (11) are formed in the cage, and each group of pockets has multiple pockets. The pockets in any group are distributed along the circumference direction of the said cage, and a group of rollers is disposed in each pocket. Multi-group rollers can roll in circumferential direction of the cage. During the rolling process, a great number of contact points are distributed on the raceways, thus the load capacity of the bearing is improved, the friction resistance is low, suitable for the fields where high speed operation is necessary. A planar thrust bearing, a radial bearing and a conical radial-thrust bearing are provided.

Abstract: An apparatus to facilitate supporting vector multiply add with double accumulator access in a graphics environment is disclosed. The apparatus includes a processor comprising processing resources, the processing resources comprising multiplier circuitry to: receive operands for a matrix multiplication operation, wherein the operands comprising two source matrices to be multiplied as part of the matrix multiplication operation; and issue a multiply and add vector (MADV) instruction for the multiplication operation utilizing a double accumulator access output, wherein the MADV instruction to multiply two vectors of the two source matrices in a single floating point (FP) pipeline of the processor.

Abstract: Determination and provision of improved representations of program flow control are provided by a method that monitors execution of binary code of a program on a computer system. The monitoring includes monitoring manipulation(s) of call stack(s) maintained by the computer system for the execution of the binary code. The method, based on the monitoring, determines function call pattern(s) and branch pattern(s) exhibited by the execution of the binary code. The method identifies, from the binary code and using the determined function call pattern(s) and branch pattern(s), function calls and branches, relations between the function calls and branches, and function and variable names. The method also provides a representation of program flow control of the program using the identified function calls and branches, relations, and function and variable names.

Abstract: Determination and provision of improved representations of program flow control are provided by a method that monitors execution of binary code of a program on a computer system. The monitoring includes monitoring manipulation(s) of call stack(s) maintained by the computer system for the execution of the binary code. The method, based on the monitoring, determines function call pattern(s) and branch pattern(s) exhibited by the execution of the binary code. The method identifies, from the binary code and using the determined function call pattern(s) and branch pattern(s), function calls and branches, relations between the function calls and branches, and function and variable names. The method also provides a representation of program flow control of the program using the identified function calls and branches, relations, and function and variable names.

Abstract: Methods and systems are provided for cooling hot spots on a body coil assembly of an MRI system. In one embodiment, an airflow guide of a body coil assembly of an MRI system comprises a first surface that forms an air passage when the airflow guide is positioned on the body coil assembly, the air passage enclosed by the first surface and a second, outer surface of an RF coil of the body coil assembly, the airflow guide configured to channel cool air generated by a fan to the second, outer surface of the RF coil. The airflow guide may be arranged circumferentially around a portion of the RF coil at one or more ends of the RF coil. The airflow guide may be manufactured as a plurality of airflow guide segments that are glued together.

Abstract: The present disclosure relates to systems for the expression of antibodies or antigen binding fragments in a subject, as well as methods of treatments of diseases therewith.

Abstract: A nutation reducer includes: a case, two pairs of nutation gear pairs, each pair being disposed in the case and composed of a nutation gear and non-nutation gear in engagement, and the non-nutation gear being fixed in the case or integrated formed in the case; an output shaft, rotationally disposed in the case; two annular spring films, each nutation gear of the gear pair is connected to the output shaft through one annular spring film; a nutation generating mechanism disposed in the case, two nutation gear pairs being respectively disposed on both sides of the nutation generating mechanism. Power-split arrangement is applied in this application, symmetric layout of the nutation gear pairs is adopted. In this way, the working efficiency of the reducer is obviously improved, meanwhile the volume and weight of the reducer, and the heat generated in working process are reduced, and power density is improved.

Abstract: A near eye display system is provided. The near eye display system includes: a frame; a first near eye display mounted on the frame and configured to form a first image directly projected on a first retina of a first eye of a user; a second near eye display mounted on the frame and configured to form a second image directly projected on a second retina of a second eye of the user; and a processing unit located at the frame and configured to generate a display control signal to drive the first near eye display and the second near eye display.

Abstract: A computer-implemented method, computer program product and computer system are provided. A processor receives an indication of sensitive data in one or more files. A processor updates at least one bit in the virtual address space for the one or more files indicated to have sensitive data. A processor, in response to a program accessing the one or more files, evaluates a respective virtual address for the one or more files. A processor, in response to the at least one bit in the respective virtual address for the one or more files, marks intermediate data generated by the program as sensitive data.

Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.