Abstract: This invention discloses a medicinal composition includes a non-coding RNA molecule and an antibody targeting a tumor antigen for preventing and/or treating cancer. This invention uses the synergistic combination of a non-coding RNA molecule or its functional variant or homologue, and an antibody targeting a tumor antigen to prevent and/or treat cancer, thereby providing a novel and effective method in preventing and/or treating various cancers.

Abstract: A memory device includes: a first conductor extending in parallel with a first axis; a first selector material comprising a first portion that extends along a first sidewall of the first conductor; a second selector material comprising a first portion that extends along the first sidewall of the first conductor; a first variable resistive material comprising a portion that extends along the first sidewall of the first conductor; and a second conductor extending in parallel with a second axis substantially perpendicular to the first axis, wherein the first portion of the first selector material, the first portion of the second selector material, and the portion of the first variable resistive material are arranged along a first direction in parallel with a third axis substantially perpendicular to the first axis and second axis.

Abstract: A bearing cage assembly comprises multi-group rollers (2), each group has multiple rollers, and each roller is a barrel roller, multiple rollers are stacked together to form a group of rollers, and the end surfaces of each two adjacent rollers contact with each other. Multiple groups of pockets (11) are formed in the cage, and each group of pockets has multiple pockets. The pockets in any group are distributed along the circumference direction of the said cage, and a group of rollers is disposed in each pocket. Multi-group rollers can roll in circumferential direction of the cage. During the rolling process, a great number of contact points are distributed on the raceways, thus the load capacity of the bearing is improved, the friction resistance is low, suitable for the fields where high speed operation is necessary. A planar thrust bearing, a radial bearing and a conical radial-thrust bearing are provided.

Abstract: The present invention provides a composition comprising dendritic cells loaded with hHsp60sp, which dendritic cells are from a subject and have been fixed with paraformaldehyde (PFA). The subject may suffer from an autoimmune disease. Also provided are a method for preparing the composition; recombinant human cells comprising a heterologous gene encoding a fusion protein of HLA-E and hHsp60sp or B7sp, and expressing the fusion protein on the surface of the cells; a method for determining a percentage of maximum inhibition of testing the function of the HLA-E restricted CD8+ Treg cells from a subject, determining whether HLA-E restricted CD8+ Treg cells freshly isolated from a subject are defective, or determining whether defective HLA-E restricted CD8+ Treg cells from a subject are correctable; and a method for correcting defective HLA-E restricted CD8+ Treg cells, treating type 1 diabetes (T1D), or treating multiple sclerosis (MS).

Abstract: An apparatus to facilitate supporting vector multiply add with double accumulator access in a graphics environment is disclosed. The apparatus includes a processor comprising processing resources, the processing resources comprising multiplier circuitry to: receive operands for a matrix multiplication operation, wherein the operands comprising two source matrices to be multiplied as part of the matrix multiplication operation; and issue a multiply and add vector (MADV) instruction for the multiplication operation utilizing a double accumulator access output, wherein the MADV instruction to multiply two vectors of the two source matrices in a single floating point (FP) pipeline of the processor.

Abstract: Methods and systems are provided for cooling hot spots on a body coil assembly of an MRI system. In one embodiment, an airflow guide of a body coil assembly of an MRI system comprises a first surface that forms an air passage when the airflow guide is positioned on the body coil assembly, the air passage enclosed by the first surface and a second, outer surface of an RF coil of the body coil assembly, the airflow guide configured to channel cool air generated by a fan to the second, outer surface of the RF coil. The airflow guide may be arranged circumferentially around a portion of the RF coil at one or more ends of the RF coil. The airflow guide may be manufactured as a plurality of airflow guide segments that are glued together.

Abstract: The present disclosure relates to systems for the expression of antibodies or antigen binding fragments in a subject, as well as methods of treatments of diseases therewith.

Abstract: A nutation reducer includes: a case, two pairs of nutation gear pairs, each pair being disposed in the case and composed of a nutation gear and non-nutation gear in engagement, and the non-nutation gear being fixed in the case or integrated formed in the case; an output shaft, rotationally disposed in the case; two annular spring films, each nutation gear of the gear pair is connected to the output shaft through one annular spring film; a nutation generating mechanism disposed in the case, two nutation gear pairs being respectively disposed on both sides of the nutation generating mechanism. Power-split arrangement is applied in this application, symmetric layout of the nutation gear pairs is adopted. In this way, the working efficiency of the reducer is obviously improved, meanwhile the volume and weight of the reducer, and the heat generated in working process are reduced, and power density is improved.

Abstract: A near eye display system is provided. The near eye display system includes: a frame; a first near eye display mounted on the frame and configured to form a first image directly projected on a first retina of a first eye of a user; a second near eye display mounted on the frame and configured to form a second image directly projected on a second retina of a second eye of the user; and a processing unit located at the frame and configured to generate a display control signal to drive the first near eye display and the second near eye display.

Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Abstract: A display device and method of manufacturing thereof is provided. The display device includes: a substrate; a plurality of control transistors disposed in the substrate; a multi-layer interconnect (MLI) structure on the substrate; and a luminous device layer disposed on the MLI structure. The luminous device layer includes a plurality of sub-pixels corresponding to the plurality of control transistors, respectively. The MLI structure includes a plurality of routing features and at least one light blocking feature, and the plurality of routing features electrically connect each of the plurality of control transistors to the corresponding sub-pixel, and the at least one light blocking feature is operable to block stray light generated by the luminous device layer.

Abstract: Method and apparatus for deriving a motion vector at a video decoder. A block-based motion vector may be produced at the video decoder by utilizing motion estimation among available pixels relative to blocks in one or more reference frames. The available pixels could be, for example, spatially neighboring blocks in the sequential scan coding order of a current frame, blocks in a previously decoded frame, or blocks in a downsampled frame in a lower pyramid when layered coding has been used.

Abstract: The present disclosure discloses ?-carrageenase mutant OUC-CglA-DPQQ, which has an amino acid sequence as set forth in SEQ ID NO. 1 and an encoding gene as set forth in SEQ ID NO. 2. The ?-carrageenase mutant OUC-CglA-DPQQ is applied to degradation of carrageenan/preparation of ?-carrageenan oligosaccharides with high polymerization degree. The present disclosure further discloses a method for degrading carrageenan/preparing ?-carrageenan oligosaccharides with high polymerization degree by using the ?-carrageenase mutant OUC-CglA-DPQQ. The ?-carrageenase mutant OUC-CglA-DPQQ of the present disclosure can act on low viscosity carrageenan, and the polymerization degree of final product ?-carrageenan oligosaccharides is 10-20. The ?-carrageenase mutant of the present disclosure is excellent in enzymatic properties and specificity, and has important industrial application value and economic value in the preparation of ?-carrageenan oligosaccharides via an enzyme method.

Abstract: Disclosed are a biomarkers composition related to diagnosis and prognosis of immunoglobulin A nephropathy (IgAN) and application thereof, belonging to the field of biomedicine. The biomarkers composition includes at least one of cytokines of FCAR, MBL and MMP-9. It is found after screening and analysis that FCAR, MBL and MMP-9 are associated with the diagnosis of IgAN, especially with severe IgAN. With protein microarray, patients of mild IgAN and severe IgAN, and healthy people are distinguished with high specificity and sensitivity according to the present disclosure.

Abstract: A near eye display system is provided. The near eye display system includes: a frame comprising a main body and two temple arms; at least one near eye sensor mounted on the main body and configured to measure user eye parameters; a first near eye display mounted on the main body and configured to form a first image projected on a first retina of a first eye; a second near eye display mounted on the main body and configured to form a second image projected on a second retina of a second eye; and a processing unit located at least at one of the two temple arms and configured to generate a display control signal based at least on the user eye parameters, wherein the display control signal drives the first near eye display and the second near eye display.

Abstract: A bakuchiol derivative, a pharmaceutically acceptable salt thereof, and a preparation method and use of the same. The bakuchiol derivative has a structure shown in formula (I): The above series of amphiphilic antibacterial compounds based on bakuchiol have comparatively excellent antibacterial activities and can overcome the generation of drug resistance of bacteria in drug resistance research simulated in a laboratory.

Abstract: The present disclosure provides a semiconductor device. The semiconductor device includes: a substrate, having a first side and a second side opposite to the first side, wherein the substrate includes a plurality of trenches at the second side; a device layer, disposed on the first side of the substrate; an interconnect layer, disposed on the device layer; a luminous layer, disposed on the interconnect layer; and a capping layer, conformally disposed on the second side of the bended substrate. The semiconductor device is convexly curved.

Abstract: Methods and systems are provided for cooling hot spots on a body coil assembly of an MRI system. In one embodiment, an airflow guide of a body coil assembly of an MRI system comprises a first surface that forms an air passage when the airflow guide is positioned on the body coil assembly, the air passage enclosed by the first surface and a second, outer surface of an RF coil of the body coil assembly, the airflow guide configured to channel cool air generated by a fan to the second, outer surface of the RF coil. The airflow guide may be arranged circumferentially around a portion of the RF coil at one or more ends of the RF coil. The airflow guide may be manufactured as a plurality of airflow guide segments that are glued together.

Abstract: Embodiments described herein provide a system of concurrent compute queues that enable the scheduling of a large number of compute contexts simultaneously on graphics processor hardware. One embodiment provides an apparatus comprising a system interface and a general-purpose graphics processor coupled with the system interface. The general-purpose graphics processor comprises a plurality of graphics processor hardware resources configured to be partitioned into a plurality of isolated partitions, each of the plurality of isolated partitions including a first command streamer, a second command streamer, and circuitry configured to schedule general-purpose graphics compute workloads submitted to a first plurality of command queues associated with the first command streamer and a second plurality of command queues associated with the second command streamer.