Abstract: The present invention relates to compounds of formula (I), wherein R1, R2, R3 and R4 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A method for calculating state of health of battery, performed by a processing control circuit, includes: charging a battery under test to an upper voltage with a first constant current through a charging circuit and an electrical measuring circuit, discharging the battery under test to a lower voltage with a second constant current through the charging circuit and the electrical measuring circuit, obtaining an accumulated discharge capacity from the upper voltage to the lower voltage through the electrical measuring circuit, and calculating a state of health of the battery under test at least according to the accumulated discharge capacity and a design capacity.

Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: The present invention relates to compounds of formula (I), wherein R1 to R6, m and n are I a described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A display may have a stretchable portion with hermetically sealed rigid pixel islands. A flexible interconnect region may be interposed between the hermetically sealed rigid pixel islands. The hermetically sealed rigid pixel islands may include organic light-emitting diode (OLED) pixels. A conductive cutting structure may have an undercut that causes a discontinuity in a conductive OLED layer to mitigate lateral leakage. The conductive cutting structure may also be electrically connected to a cathode for the OLED pixels and provide a cathode voltage to the cathode. First and second inorganic passivation layers may be formed over the OLED pixels. Multiple discrete portions of an organic inkjet printed layer may be interposed between the first and second inorganic passivation layers.

Abstract: One aspect of this disclosure is a power amplifier module that includes a power amplifier, a semiconductor resistor, a tantalum nitride terminated through wafer via, and a conductive layer electrically connected to the power amplifier. The semiconductor resistor can include a resistive layer that includes a same material as a layer of a bipolar transistor of the power amplifier. A portion of the conductive layer can be in the tantalum nitride terminated through wafer via. The conductive layer and the power amplifier can be on opposing sides of a semiconductor substrate. Other embodiments of the module are provided along with related methods and components thereof.

Abstract: A method of manufacturing a microelectronic package with an integrally formed electromagnetic interference (“EMI”) shield and/or antenna is disclosed. The method comprises patterning a conductive structure to comprise a base, a plurality of interconnection elements, and a die attach area sized to receive a microelectronic element; bonding ends of the plurality of interconnection elements to a carrier; encapsulating the plurality of interconnection elements, and the microelectronic element with an encapsulant; removing the carrier to expose free ends of the plurality of interconnection elements; patterning the exposed outer surface of the conductive structure overlying the microelectronic element to form a portion of the EMI shield structure and/or an antenna. The portion of the EMI shield structure and/or antenna can be patterned to extend continuously from one or more of the plurality of interconnection elements.

Abstract: A microelectronic device may include a substrate, a first chip on the substrate, and a second chip on the substrate. A plurality of pillars may be located between the first chip and the second chip, wherein a first end of each pillar of the plurality of pillars is adjacent to the substrate. A spacing among the plurality of pillars is at least equal to a distance sufficient to block electromagnetic interference (EMI) and/or radio frequency interference (RFI) between the first chip and the second chip. The microelectronic device may also include a cover over at least the first chip, the second chip, and the plurality of pillars, wherein a second end of each pillar of the plurality of pillars is at least adjacent to a trench defined within the cover. The trench may include a conductive material therein.

Abstract: A control circuit for controlling a power module is provided. The power module drives a processing circuit. The control circuit includes a first resistor, a second resistor, a trigger circuit, and a switch circuit. The first resistor is coupled between a first reference voltage and a setting input terminal. The second resistor is coupled between a second reference voltage and the setting input terminal. The trigger circuit provides a switching signal in response to an operating signal. The switch circuit transmits a control signal to the setting input terminal in response to a first voltage level, and stops transmitting the control signal in response to a second voltage level. The power module executes one of a first power supply mode and a second power supply mode in response to a voltage value. When the control signal is not received, the power module executes a third power supply mode.

Abstract: An electronic device comprises a processing circuit, which is configured to determine a base-station-side first beam transmitting direction of a base station for a direct link of a user equipment and a base-station-side second beam transmitting direction of the base station for a reflection link of a large intelligent surface (LIS). On the basis of the base-station-side first beam transmitting direction and the base-station-side second beam transmitting direction, the processing circuit determines a first scanning range of the LIS for a reflected beam of a reflection link of the user equipment and a second scanning range of the LIS for a received beam of the user equipment. Additionally, the processing circuit executes control to perform beam training on the reflection link between the LIS and the user equipment on the basis of the first scanning range and the second scanning range.

Abstract: A method of manufacturing a microelectronic package with an integrally formed electromagnetic interference (“EMI”) shield and/or antenna is disclosed. The method comprises patterning a conductive structure to comprise a base, a plurality of interconnection elements, and a die attach area sized to receive a microelectronic element; bonding ends of the plurality of interconnection elements to a carrier; encapsulating the plurality of interconnection elements, and the microelectronic element with an encapsulant; removing the carrier to expose free ends of the plurality of interconnection elements; patterning the exposed outer surface of the conductive structure overlying the microelectronic element to form a portion of the EMI shield structure and/or an antenna. The portion of the EMI shield structure and/or antenna can be patterned to extend continuously from one or more of the plurality of interconnection elements.

Abstract: A microelectronic device may include a substrate, a first chip on the substrate, and a second chip on the substrate. A plurality of pillars may be located between the first chip and the second chip, wherein a first end of each pillar of the plurality of pillars is adjacent to the substrate. A spacing among the plurality of pillars is at least equal to a distance sufficient to block electromagnetic interference (EMI) and/or radio frequency interference (RFI) between the first chip and the second chip. The microelectronic device may also include a cover over at least the first chip, the second chip, and the plurality of pillars, wherein a second end of each pillar of the plurality of pillars is at least adjacent to a trench defined within the cover. The trench may include a conductive material therein.

Abstract: The present invention provides flavone derivatives having the general formula (I) which are useful for the treatment of Hepatitis B Virus infection (HBV). The compounds act as cccDNA (covalently closed circular DMA) inhibitors.

Abstract: The present invention provides compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.

Abstract: The present disclosure relates to the field of preparation of compound semiconductor nanomaterials, and in particular to a method for in-situ modification of mercury quantum dots in a traditional thermal injection process. It is characterized in that, in the traditional thermal injection process for synthesis of HgTe quantum dots, after a certain reaction time, a low boiling point polar solvent that is incompatible with a reaction solvent is rapidly injected, so that an interfacial separation of two liquid phases occurs in a mixed reaction, and then a selective crystal oriented surface modification is conducted on surfaces of mercury quantum dots.

Abstract: A puncture instrument kit includes a puncture rod, mesh, and sheath. The puncture rod consists of a puncture head, puncture rod body, and handle. One end of the puncture rod body is connected to the handle and the other end is integrated with the puncture head. The puncture head is arc-shaped with an end gradually tapering to form a tip. The tip of the puncture head is circumferentially designed with a groove for fixing a thread during surgery. The puncture head is smoothly connected with the puncture rod body, and the line between the tip of the puncture head and puncture rod body is at an obtuse angle of 130-140° relative to the puncture rod body. The sheath is sleeved on the puncture rod with the rod tip exposed. The mesh and sheath are designed as separate or integrated, and the tip of the puncture rod is provided with a shape-matching detachable silicone protective sleeve.

Abstract: A method for calculating state of health of battery, performed by a processing control circuit, includes: charging a battery under test to an upper voltage with a first constant current through a charging circuit and an electrical measuring circuit, discharging the battery under test to a lower voltage with a second constant current through the charging circuit and the electrical measuring circuit, obtaining an accumulated discharge capacity from the upper voltage to the lower voltage through the electrical measuring circuit, and calculating a state of health of the battery under test at least according to the accumulated discharge capacity and a design capacity.

Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.