Abstract: A fresh water generator utilizing air (100) comprises a main body bracket (114), a water making system, a water purifying system and a water distributing device (126). Both sides and the rear side of the main body bracket (114) are provided with panels, on which ventilating grilles (116, 132, 134) are provided for sucking and exhausting air. The water making system is arranged inside the main body bracket (114) and particularly comprises a condenser/evaporator unit (118), an exhaust fan (140) and a water collecting tank (120), wherein the water collecting tank (120) is arranged on the main body bracket (114) and positioned at the lower end of the condenser/evaporator unit (118), and the exhaust fan (140) is arranged between the condenser/evaporator unit (118) and the ventilating grates (116, 132, 134). The water purifying system is arranged inside the main body bracket (114) and particularly comprises a pump (122) and a filtration device (192).

Abstract: Disclosed is a system and technique for validating a user for a single sign on without exposing secure information about the user to any part of the system except the connection server and the identity provider. In the technique, instead of relying directly on a SAML assertion, the technique uses an artifact representing the assertion and wraps the artifact in an access token. The access token is able to carry the artifact through one or more gateways on its way to a connection server without revealing any security information. Upon the access token being verified by either the gateway or the connection server, the artifact can be extracted from the access token and verification of the user for the single sign on can proceed between only the connection server and the identity provider.

Abstract: A toy building block set includes a socket block piece and at least one of first and second plug block pieces. The socket block piece has a socket wall body and at least one engaging hole of a regular polygonal shape. Each of the first and second plug block pieces has a plug body and at least one polygonal insert plug configured to be inserted into and in frictional engagement with the engaging hole with a first frictional force to permit rotation of the plug block piece relative to the socket block piece by a forcible torque and to keep a predetermined angle of the plug block piece relative to the socket block piece when the forcible torque is removed. The plug body is partially inserted into and in frictional engagement with the engaging hole with a second frictional force larger than the first frictional force.

Abstract: The present invention provides super-hydrophobic fabrics and a preparation method thereof, and belong to the field of textiles. The super-hydrophobic fabrics are obtained by finishing Pickering emulsion formed by amphiphilic particles stabilizing low-surface-energy substances in water. Via a one-step finishing method using Pickering emulsion technology, facile preparation of durable super-hydrophobic fabrics is realized. The static contact angle between the finished fabric surfaces and water droplets is greater than 150 degrees, and the water droplets can roll off easily; and after being subjected to 30 times of standard washing tests, the finished fabrics still maintains excellent water repellency. In addition, the Pickering emulsion preparation and finishing process of the present invention are environmentally friendly, pollution-free, facile to operate and widely applicable.

Abstract: An LED tube lamp comprises a lamp tube, a first circuit board disposed in the lamp tube having a plurality of light sources mounted thereon, and two lamp caps respectively disposed at both ends of the lamp tube and having a power supply disposed in the lamp caps. The power supply has a second circuit board with a first surface and a second surface opposite and parallel to each other. The lamp cap comprises a side wall, an end wall, and a slot with a first rib. There is a coupling structure protruded on the first rib with respect to the first surface of the second circuit board.

Abstract: The present invention discloses an outdoor gas heater, comprising an outer cover, an outer cover side baffle, a gas injection pipe, a ceramic burner, a body box, a control box connecting support frame, a control box sealing plate, a control box, a wall-mounted bracket and a long open a flame connecting pipe. Four ceramic burners are fixed side by side in the body box, a gas injection pipe is fixed on the lower side of the body box, and a gas injection pipe is sealingly connected to the four ceramic burners; the outer open end of the body box is locked to the outer cover, and the side of the body box opposite to the outer opening thereof is locked to the control box connecting support frame. The control box connecting support frame is a U-shaped structure, and side wall of which is locked on both sides of the control box, and the outer side opening of the control box is locked to the control box sealing plate; the side of the control box opposite to the outer opening is locked to the wall-mounted bracket.

Abstract: The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein. The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-positive cancer in a subject in need thereof.

Abstract: Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2-related cancers.

Abstract: This application provides a latency-based transmission path control method, an apparatus, and a system. Device latencies of network node devices on an active transmission path, device latencies of network node devices on a standby transmission path, latencies of links between the network node devices on the active transmission path, and latencies of links between the network node devices on the active transmission path are obtained, and calculation is performed based on the respective device latencies and link latencies to obtain an active transmission path latency and a standby transmission path latency. Then, based on a latency-based switching mechanism, when the active transmission path latency is greater than a switching threshold and the standby transmission path latency is less than the switching threshold, an active-to-standby path switching command is generated.

Abstract: The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. Also the present invention relates to the use of hetero-oligomeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. Further, the invention relates to the constitutive of cell lines that stably or transiently co-express a combination of T1R1 and T1R3; or T1R2 and T1R3; under constitutive or inducible conditions.

Abstract: The present invention discloses a polyvinyl chloride floor with high stain resistance and easy cleaning functions. The polyvinyl chloride floor includes a polyvinyl chloride floor layer and a stain-resistant surface layer, wherein the stain-resistant surface layer is formed by co-extruding an outer protective layer, a functional layer and an adhesive layer; the outer protective layer is a fluorine-containing polymer; the functional layer is formed by mixing the fluorine-containing polymer, a hot melt adhesive and functional aids; the adhesive layer is formed by mixing the fluorine-containing polymer and the hot melt adhesive; and the stain-resistant surface layer is in hot-melt adhesion connection with the polyvinyl chloride floor layer through the adhesive layer. The present invention has advantages of green environmental protection, high wear resistance, water resistance, moisture resistance, bacterial resistance, stain resistance and difficulty in leaving traces.

Abstract: A method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described.

Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.

Abstract: The present invention discloses an L-type amylase variant and use thereof. The ?-amylase variant is obtained by deleting the first N-terminal amino acid residue V from the ?-amylase of B. licheniformis and replacing it with three other amino acid residues DGL. The ?-amylase variant provided by the present invention has high catalytic activity under the acidic conditions of pH 5.0-5.8 and a high temperature of 100° C. or above. The acid resistance and thermal stability of these ?-amylase variants are suitable for starch liquefaction.

Abstract: Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.

Abstract: An LED tube lamp having: a lamp tube, which includes a light transmissive portion, a reinforcing portion and an end cap; and an LED light assembly, which includes an LED light source and an LED light strip. The light transmissive portion is fixedly connected to the reinforcing portion. The reinforcing portion includes a platform and a bracing structure. The bracing structure is fixedly connected to the platform and holds the platform in place. The LED light source is thermally and electrically connected to the LED light strip, which is in turn thermally connected to the reinforcing portion. The end cap is attached to an end of the lamp tube. An outer surface of the lamp tube reveals a combination of metallic outer surface and nonmetallic outer surface.

Abstract: The invention involves an LED tube lamp, which comprises a lamp tube, which includes a light transmissive portion, a reinforcing portion and an end cap. The LED tube lamp further includes an LED light assembly, which includes an LED light source and an LED light strip. The light transmissive portion is fixedly connected to the reinforcing portion. The LED light strip abuts against the reinforcing portion, which holds the LED light assembly in place. The LED light source is thermally and electrically connected to the LED light strip, which is in turn thermally connected to the reinforcing portion. The end cap is attached to an end of the lamp tube. A ratio of a cross-sectional area of the reinforcing portion to a cross-sectional area of the lamp tube is from 1:3 to 1:30.

Abstract: A LED filament comprises a frame, a metal electrode, a fasten member, a second fasten member, at least one LED chip. The frame is a bottomless frame and the metal electrode is disposed on one side of the frame. The first fasten member is formed on the frame and the second fasten member formed on the metal electrode. The metal electrode having the second fasten member is placed on the first fasten member of the frame, thereby fastening the metal electrode on the frame; wherein one of the first fasten member and the second fasten member is a protrusion while the other one is a hole. The at least one LED chip disposed inside the frame and electrically connecting to the metal electrode.

Abstract: Newly identified mammalian taste-cell-specific G protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for identifying putative taste modulating compounds using such hetero-oligomeric complexes also described, as is a novel surface expression facilitating peptide useful for targeting integral plasma membrane proteins to the surface of a cell.

Abstract: The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric and chimeric taste receptors comprising T1R1/T1R3 and T1R2/T1R3 in assays to identify compounds that respectively respond to umami taste stimuli and sweet taste stimuli. Further, the invention relates to the constitutive of cell lines that stably or transiently co-express a combination of T1R1 and T1R3; or T1R2 and T1R3; under constitutive or inducible conditions. The use of these cells lines in cell-based assays to identify umami and sweet taste modulatory compounds is also provided, particularly high throughput screening assays that detect receptor activity by use of fluorometric imaging.