Abstract: Disclosed are a method and apparatus for safety control of radio frequency operation, and a radio frequency host. The method includes: when connecting ends of a plurality of radio frequency circuits connect an operated object to a radio frequency host, acquiring detection values of the plurality of radio frequency circuits; determining whether change amounts of the detection values reach a preset value range; when a number of target radio frequency circuits reaching the preset value range is not less than a preset number, selecting the preset number of target radio frequency circuits from the target radio frequency circuits according to a preset selection rule as radio frequency input circuits, and inputting radio frequency energy into the radio frequency input circuits; when the number of target radio frequency circuits reaching the preset value range is less than the preset number, not inputting radio frequency energy into any radio frequency circuit.

Abstract: A multi-path perfusion control method and apparatus for injection pump, an injection pump and a storage medium, wherein the method includes: controlling the injection pump to open at least one perfusion channel when an ablation task is triggered, so as to execute a perfusion operation through an opened perfusion channel according to a preset initial flow rate; acquiring temperatures of a plurality of positions of an ablation object in real time by a plurality of temperature acquisition apparatuses; and controlling the injection pump to open or close some or all of the perfusion channels and/or adjust flow rates of some or all of the perfusion channels according to a real-time change in the temperatures of the plurality of positions. Operation delay or operation errors caused by manual determination can be reduced, and the timeliness, accuracy and pertinence of liquid perfusion during executing the ablation task can also be improved.

Abstract: Disclosed are an ablation operation prompting method, an electronic device, and a computer-readable storage medium. The method includes: acquiring an image of an ablation site and displaying the image on a screen when an ablation task is triggered; acquiring position data of a currently-being-ablated target ablation point, marking the target ablation point in the image according to the position data; acquiring the elapsed ablation time and the temperature of the target ablation point in real time, and determining the ablation status of the target ablation point according to the elapsed ablation time and the temperature; and generating a schematic real-time dynamic change diagram of the target ablation point according to the ablation status, and displaying the schematic diagram on the screen, to indicate the real-time ablation status change of the target ablation point.

Abstract: A perfusion control method, apparatus and system for syringe pump, and a computer-readable storage medium, wherein the method includes: when an ablation task is triggered, controlling the syringe pump to execute a perfusion operation on an ablation object, and acquiring an impedance value and/or a temperature value of the ablation object in real time; analyzing the acquired impedance value and/or temperature value to obtain real-time change information of the impedance value and/or temperature value; and adjusting a perfusion amount of the syringe pump dynamically according to the real-time change information obtained from the analysis. By means of the perfusion control method, apparatus and system for syringe pump, and the computer-readable storage medium, dynamic adjustment of the perfusion amount of the syringe pump can be achieved, thereby improving the timeliness and accuracy of liquid perfusion during the process of executing an ablation task.

Abstract: A method and an apparatus for dynamically adjusting a radio frequency parameter, and a radio frequency host are provided. The method includes: determining an operation stage of a radio frequency operation and acquiring a radio frequency data standard range and limit range corresponding to an operation object of the radio frequency operation at the operation stage; detecting radio frequency data of the operation object in real time; controlling the radio frequency data to be within the radio frequency data standard range by controlling an injection volume of a syringe pump to the operation object when the radio frequency data detected in real time exceeds the radio frequency data standard range but does not exceed the radio frequency data limit range and lasts for a preset duration; and stopping outputting radio frequency energy when the radio frequency data detected in real time exceeds the radio frequency data limit range.

Abstract: Disclosed are a protection method for radio frequency operation abnormality, a radio frequency host, and a radio frequency operation system. The protection method for radio frequency operation abnormality includes: detecting preset kinds of detection data of a radio frequency operation in real time when detecting that a radio frequency host continuously outputs radio frequency energy; determining whether detected preset kinds of detection data meets a preset abnormal state; and when the preset abnormal state is met, controlling a radio frequency generating apparatus to stop outputting radio frequency energy and controlling an emergency stop apparatus to cut off a radio frequency energy output path of the radio frequency host. By means of dual protection for operation abnormality, safety of radio frequency operation is improved.

Abstract: Embodiments of the present disclosure disclose a radio-frequency ablation catheter and a radio-frequency ablation system. The radio-frequency ablation catheter includes a needle tube portion and a handle portion. A sleeve of the handle portion is sleeved on a booster of the handle portion. A puncture tube of the needle tube portion is fixed to an end of the sleeve. An electrode tube and a signal conduit of the needle tube portion are disposed within the puncture tube in a penetrating fashion. A plurality of sub-needles are disposed on the electrode tube and a plurality of supports are disposed on the signal conduit. The plurality of supports correspond to the plurality of sub-needles respectively. A plurality of temperature sensors are disposed at ends of the plurality of supports.

Abstract: The present disclosure relates generally to immunoglobulin-related compositions such as antibodies or antigen binding fragments thereof that can bind to and neutralize the activity of A33 protein. The antibodies of the present technology are useful in methods for detecting and treating an A33-positive cancer in a subject in need thereof.

Abstract: An artificial intelligence assisted medical diagnosis method for a sepsis is proposed. A database reading step is performed to read a sepsis database and at least one database to be tested of a storing unit. The sepsis database includes a plurality of sepsis data, and the at least one database to be tested includes a plurality of data to be tested. A data table creating step is performed to create a sepsis data table according to the sepsis data, and create a data table to be tested according to the data to be tested. A model training step is performed to train the sepsis data table according to a K-fold cross-validation and a machine learning algorithm to generate a sepsis diagnosis model. A sepsis predicting step is performed to input the data table to be tested into the sepsis diagnosis model to calculate a sepsis prediction result.

Abstract: A radio-frequency ablation catheter comprises a handle having a proximal end and a distal end, an outer tube assembly having a proximal end and a distal end, and an inner tube assembly having a proximal end and a distal end; the proximal end of the outer tube assembly is connected to the distal end of the handle; the proximal end of the inner tube assembly is connected to the distal end of the handle; the inner tube assembly can be driven by the handle to rotate relative to the outer tube assembly; the inner tube assembly comprises a branch electrode assembly, and the branch electrode assembly comprises a plurality of branch electrodes distributed at intervals in the circumferential direction. The branch electrode assembly of the radio-frequency ablation catheter and the radio-frequency ablation system can rotate relative to the outer tube assembly to avoid blood vessels.

Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.

Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program. The program receives, from a client device, a request for information associated with a category. In response to the request, the program further accesses a storage to retrieve a first value associated with the category. The program also determines a set of values associated with the category based on a plurality of transactions. The program further determines an optimization level value associated with the category. The program also determines a second value associated with the category based on the first value, the set of values, and the optimization level value. The program further provides, by an application operating on the device, a graphical user interface (GUI) to the client device, the GUI comprising the second value.

Abstract: A circuit board structure includes a rigid circuit board, a flexible circuit board, a plurality of conductive bumps, and a plurality of spacers. The rigid and flexible circuit boards are stacked one above the other. The conductive bumps are formed between the rigid and flexible circuit boards. The spacers are formed between the rigid and flexible circuit boards and spaced apart from the conductive bumps.

Abstract: A flow cell includes a flow cell body. The flow cell body includes a frame and a fluid chamber defined in the flow cell body. The fluid chamber includes a reaction region allowing a fluid flow. A liquid inlet, a liquid outlet, and two exhaust holes connected to the fluid chamber are in the frame. Fluid into the liquid inlet flows through the reaction region in the fluid chamber and flows out through the liquid outlet. The exhaust holes discharge gas generated in the fluid chamber during the fluid flow. A flow cell with integral sealing rings and a biochemical substance reaction device are also disclosed.

Abstract: Disclose are a radio-frequency ablation catheter and a radio-frequency ablation system. The radio-frequency ablation catheter includes a needle tube portion and a handle portion. A sleeve of the handle portion is mounted around a booster of the handle portion. A puncture tube of the needle tube portion is fixed to an end of the sleeve. An electrode tube and a signal conduit of the needle tube portion are disposed passing through the puncture tube. A plurality of needles are provided on the electrode tube and a plurality of supports are provided on the signal conduit. The plurality of supports correspond to the plurality of needles respectively. A plurality of temperature sensors are provided at ends of the plurality of supports.

Abstract: Disclosed are a detection mechanism, a radio-frequency ablation catheter, and a radio-frequency ablation system. The radio-frequency ablation catheter includes a handle portion, a needle tube portion, a central electrode, and a detection mechanism. The needle tube portion includes a first tube and a second tube, the handle portion includes a cylinder sleeve and a sliding button, the central electrode includes an electrode body, an electrode wire, and an electrode connector, and the detection mechanism includes a fixing base, a pulling string, a connecting base, and multiple detection electrodes arranged in a claw-shaped configuration. A distal end of the pulling string is fixed to the fixing base, and a proximal end of the pulling string is fixed to the sliding button; and the detection electrodes are fixed to the fixing base, and slidably provided in the connecting base.

Abstract: A lung denervation method comprises advancing a catheter along the airway; deploying an open loop in contact with the epithelium; simultaneously delivering radio frequency energy from a plurality of discrete spaced-apart locations along the loop to target regions according to a set of ablation parameters sufficient to heat and interrupt nerve functionality; and forming a liquid film between the loop and the epithelium for minimizing collateral damage. The method serves to destroy motor axons of the peripheral bronchial nerve, blocks parasympathetic transmission in the pulmonary and reduces acetylcholine release, reducing airway smooth muscle tension and mucus production. Related systems are described.

Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 ?m thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.

Abstract: The present invention provides super-hydrophobic fabrics and a preparation method thereof, and belong to the field of textiles. The super-hydrophobic fabrics are obtained by finishing Pickering emulsion formed by amphiphilic particles stabilizing low-surface-energy substances in water. Via a one-step finishing method using Pickering emulsion technology, facile preparation of durable super-hydrophobic fabrics is realized. The static contact angle between the finished fabric surfaces and water droplets is greater than 150 degrees, and the water droplets can roll off easily; and after being subjected to 30 times of standard washing tests, the finished fabrics still maintains excellent water repellency. In addition, the Pickering emulsion preparation and finishing process of the present invention are environmentally friendly, pollution-free, facile to operate and widely applicable.

Abstract: A lung tumor ablation method includes deploying a plurality of sensors in the tumor margin and monitoring ablation progress based on information from the sensors. An ablation electrode is inserted into a central region of the tumor and the site is irrigated. Power and irrigation flowrate are controlled to optimize ablation based on information from the sensors. Related apparatus and systems are described.