Abstract: A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.

Abstract: An adhesive compound can include an uncured epoxy film having a curing temperature between about 80° C. and about 300° C. The uncured epoxy film can include a cresol novolac resin and a bisphenol A epoxy resin. The uncured epoxy film can have a thickness between about 0.1 mil and about 5 mil.

Abstract: Disclosed herein are systems and methods that relate to use of ultramicroelectrodes (UME) in measurement of ion concentration in presence of one or more organic compound(s).

Abstract: Provided herein are anode assembly, conductive contact strips, electrochemical cells containing the anode assembly and the conductive contact strips, and methods to use and manufacture the same, where the anode assembly includes a plurality of V-shaped, U-shaped, or Z-shaped elements positioned outside the anode shell and in electrical contact with the anode.

Abstract: Device testing using radio-frequency identification (RFID) is described herein. The testing uses one or more RFID readers that interrogate an RFID tag on a mobile device and, in response to the interrogation, receive data from the RFID tag. The one or more RFID readers, in response to receipt of the data from the RFID tag, transmit a command to execute a test program on the mobile device. The results of the test program are then provided by the mobile device.

Abstract: Methods, systems, and computer readable and executable medium embodiments for managing virtual machine pool demand are described herein. One method for managing virtual machine pool demand includes determining a demand for a number of virtual machines in a pool using data received, identifying the demand for the number of virtual machines in the pool is outside a threshold number, and sending a request for an additional virtual machine to a user to manage demand of the pool.

Abstract: In embodiments of RFID-based device wireless updates, a RFID reader interrogates a RFID tag of a device, and receives a response that indicates device software is not a latest version. The RFID reader communicates wireless network connection information and a file location of a device software update to the RFID tag of the device, and RFID tag memory maintains the file location and the wireless network connection information that is associated with a wireless network. The RFID reader communicates a power-up command to the RFID tag to initiate enabling an interrupt line to power the device on. A bootloader application executing on the device determines that the device software update is available. The bootloader application then obtains the wireless network connection information and configures the device for communication via the wireless network. The bootloader application also obtains the file location and downloads the device software update via the wireless network.

Abstract: Disclosed are systems biology-based methods for repositioning known pharmaceutical compounds to new indications, through the identification of network-based signatures. In particular, the invention provides new and useful methods for selecting drugs or combinations of drugs (and preferably previously-approved drugs) for use in new therapeutic indications. Also disclosed are methods for identifying anti-breast tumor initiating cell (TIC)-based therapeutics from within populations of target compounds. In illustrative embodiments, the invention provides methods and computer programs for the repositioning of FDA-approved pharmaceutical compounds to new indications using network-based signature analysis coupled with conventional in vitro and in vivo testing of identified drug candidates. The invention also allows identification of drugs or drug combinations for treating unmet medical needs including, for example, “orphan” diseases.

Abstract: A method includes providing a plurality of identification tags each associated with one of a plurality of physical locations. First identification data is read from a selected one of the plurality of identification tags designated as a home location on a device. Second identification data is read from at least a subset of the plurality of identification tags other than the selected one on the device. Directions to the home location are provided on a display of the device based on the first identification data and the second identification data.

Abstract: A method includes reading transaction initiation data from an identification tag associated with a selected physical location on a device. Transaction data associated with the selected physical location is communicated using a communication link operated by the device. Transaction completion data is received using the communication link. The transaction completion data is stored on the identification tag.

Abstract: Device testing using radio-frequency identification (RFID) is described herein. The testing uses one or more RFID readers that interrogate an RFID tag on a mobile device and, in response to the interrogation, receive data from the RFID tag. The one or more RFID readers, in response to receipt of the data from the RFID tag, transmit a command to execute a test program on the mobile device. The results of the test program are then provided by the mobile device.

Abstract: Disclosed herein are methods and systems that relate to an on-line monitoring of a process/system by controlling rate of oxidation of metal ions at an anode in an anode electrolyte of an electrochemical process and controlling rate of reduction of the metal ions in a catalysis process to achieve steady state.

Abstract: Silent radio frequency identifier (RFID) state and restore back is described herein. An RFID tag enters a silent state by receiving a sleep command from an RFID reader. While the RFID tag is in the silent state, only an awake command will restore back normal operation of the RFID tag. Other received commands or interrogations from the RFID reader are ignored and responses are not transmitted to the RFID reader.

Abstract: A system and method of model predictive control executes a model predictive control (MPC) controller of a subject dynamic process (e.g., processing plant) in a configuration mode, identification mode and model adaptation mode. Users input and specify model structure information in the configuration mode, including constraints. Using the specified model structure information in the identification mode, the MPC controller generates linear dynamic models of the subject process. The generated linear dynamic models collectively form a working master model. In model adaptation mode, the MPC controller uses the specified model structure information in a manner that forces control actions based on the formed working master model to closely match real-world behavior of the subject dynamic process. The MPC controller coordinates execution in identification mode and in model adaptation mode to provide adaptive modeling and preserve structural information of the model during a model update.

Abstract: A post mounted lamp includes: a lamp post; one or more light emitting diode (LED) devices disposed proximate to the top of the lamp post; a power factor (PF) correction circuit disposed proximate to the bottom of the lamp post; wires disposed in the lamp post to deliver PF corrected electrical power from the PF correction circuit to the one or more LED devices; and circuitry disposed proximate to the top of the lamp post to operate the one or more LED devices using the PF corrected electrical power.

Abstract: In embodiments of hardware verification with RFID-stored build information, a mobile device includes hardware components and a radio-frequency identification (RFID) tag to store build information for hardware verification of the hardware components in the mobile device. A bootloader can interrogate the RFID tag to obtain the build information and compare the build information to current information of the hardware components in the mobile device. The bootloader can then determine whether the current information matches the build information. If the current information does not match the build information, then a message can be displayed on the mobile device indicating that unauthorized hardware is installed in the mobile device.

Abstract: A heat sink is arranged to dissipate heat generated by electronic circuitry, the heat sink comprising an array of spaced cooling elements. Further, an antenna is arranged to transmit and/or receive wireless electromagnetic signals at a carrier frequency, the signals communicating data to and/or from a wireless communications device. The signals are transmitted and/or received in the form of a beam having an axis in a target direction. To enhance the directionality of the beam: the array of spaced cooling elements in the heat sink is arranged to form an electromagnetic band gap (EBG) structure tuned to the carrier frequency used by the antenna; and the antenna is placed relative to the array of cooling elements such that the EBG structure suppresses the propagation of electromagnetic energy in the signals at the carrier frequency in one or more directions other than the target direction.

Abstract: There is described a portable electronic device capable of detecting false wake conditions, and a method thereof. The portable electronic device comprises a sensor circuit and a display. The sensor circuit detects double tap data associated with user input and motion data subsequent to the double tap data within a predetermined time period. The sensor circuit also determines whether the motion data corresponds to at least one criterion associated with non-user input. The display wakes from a sleep state in response to the sensor circuit determining that the motion data corresponds to the at least one criterion. For some embodiments, the sensor circuit includes a motion sensor to detect the motion data and a sensor hub to determine whether the motion data corresponds to the at least one criterion.

Abstract: The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.

Abstract: Embodiments of adjustment of a task execution plan at runtime by a task execution engine configured to receive a plan compilation task, the plan compilation task comprising a task execution plan, are provided. An aspect includes receiving a first plan compilation task by the task execution engine through a plan compilation interface. Another aspect includes modifying a task execution plan of the first plan compilation task in response to receiving a second plan compilation task by the task execution engine, the second plan compilation task comprising a task execution plan for modifying the task execution plan of the first plan compilation task. Yet another aspect includes reading a next task in the task execution plan of the first plan compilation task and initiating the next task by the task execution engine.