Abstract: The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.

Abstract: The disclosure includes a platinum-based alloy catalyst and a preparation method thereof, a membrane electrode and a fuel cell. The method for preparing the platinum-based alloy catalyst comprises the following steps: (1) preparing nano-sized alloy particles of platinum and 3d transition metal; (2) carrying out acid treatment on the alloy particles prepared in step (1); and (3) annealing the alloy particles treated in step (2). The size of the platinum-based alloy particles is controlled, an atom number ratio of platinum to transition metal in the platinum-based alloy is controlled, and then etching and dissolution of acid is combined so that an atom number ratio of platinum to transition metal is further controlled, subsequently annealing is carried out at high temperature. The prepared platinum-based alloy catalyst improves the stability and durability of the platinum-based alloy catalyst, which supports the large-scale application of the platinum-based alloy catalyst in the fuel cell.

Abstract: Electrolytes and electrolyte additives for energy storage devices comprising silyl amine compounds or derivatives thereof are disclosed. The energy storage device comprises a first electrode and a second electrode, where one or both of the first electrode and the second electrode is a Si-based electrode, a separator between the first electrode and the second electrode, an electrolyte, and at least one electrolyte additive selected from silyl amine compounds or derivatives thereof.

Abstract: System and methods that provide a new paradigm for solving process system engineering (PSE) problems using embedded artificial intelligence (AI) techniques. The approach can facilitate process model building and deployment and benefits from emerging AI and machine learning (ML) technology. The systems and methods can define PSE problems with mathematical equations, first principles and domain knowledges, and physical and economical constraints. The systems and methods generate a dataset of recorded measurements for variables of the process, and reduce the dataset by cleansing bad quality data segments and measurements for uninformative process variables from the dataset. The dataset is then enriched by, for example, applying nonlinear transforms, engineering calculations, and statistical measurements.

Abstract: A method for replaying operations on a widget in a graphical user interface (GUI) includes acquiring, from an operation record, operation information related to the widget and a first unique identification (UID) of the widget. A widget having a second UID is determined, wherein the second UID is generated based on a call stack for creating the widget in the GUI. The second UID is the same as the first UID. It may be determined whether the widget on the GUI is operable. An operation is executed on the widget according to the operation information related to the widget.

Abstract: A method for replaying operations on a widget in a graphical user interface (GUI) includes acquiring, from an operation record, operation information related to the widget and a first unique identification (UID) of the widget. A widget having a second UID is determined, wherein the second UID is generated based on a call stack for creating the widget in the GUI. The second UID is the same as the first UID. It may be determined whether the widget on the GUI is operable. An operation is executed on the widget according to the operation information related to the widget.

Abstract: An electronic device is for identifying a LED driver which is a switched mode power supply. For example the LED driver is part of an LED luminaire. An interface (24) is adapted to be coupled to a high frequency power commutation component of the switched mode power supply, for sensing the high frequency power commutation of the switched mode power supply in driving the LED. A mapping is made between identifications of LED drivers which are switched mode power supply and characteristics of the high frequency power commutations in driving the LED of a respective switched mode power supply. Thus, a LED driver which uses a switched mode power supply can be identified corresponding to extracted characteristics of the high frequency power commutations in driving the LED. This identification can be used for energy monitoring and fault diagnosis purposes, for use in a universal low cost LED driver.

Abstract: Disclosed herein are ion exchange membranes, electrochemical systems, and methods that relate to various configurations of the ion exchange membranes and other components of the electrochemical cell.

Abstract: The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein. using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.

Abstract: A method for treating a sarcoma by administering a tyrosine kinase inhibitor and a biguanide compound. Also described is a method for treating a tumor of the Ewing Sarcoma family by obtaining a tumor sample; determining in the sample gene expression levels of ACTB, B2M, MLH1, PRKDC, XPC, APEX1, ERCC5, MMS19, or RAD23; and administering a tyrosine kinase inhibitor and a biguanide compound. Furthermore, a pharmaceutical composition for treating a Ewing family tumor is disclosed. The composition contains a tyrosine kinase inhibitor, a biguanide compound, and a pharmaceutically acceptable excipient.

Abstract: Computer-based methods and system perform root-cause analysis on an industrial process. A processor executes a hybrid first-principles and inferential model to generate KPIs for the industrial process using uploaded process data as variables. The processor selects a subset of the KPIs to represent an event occurring in the industrial process, and divides the selected data into time series. The system and methods select time intervals from the time series based on data variability and perform a cross-correlation between the loaded process variables and the selected time intervals, resulting in a cross-correlation score for each loaded process variable. Precursor candidates from the loaded process variables are selected based on the cross-correlation scores, and a strength of correlation score is obtained for each precursor candidate. The methods and system select root-cause variables from the selected precursor candidates based on the strength of correlation scores, and analyze the root-cause of the event.

Abstract: The present teachings describe a printhead assembly. The printhead assembly includes a first plate and a second plate stacked together. The printhead assembly includes a first adhesive between the first plate and the second plate for bonding the plates together. The printhead assembly includes a second adhesive surrounding an outer edge of the first adhesive wherein the second adhesive has an oxygen migration rate lower than an oxygen migration rate of the first adhesive. An oxygen sensitive component is contained within the outer edge of the first adhesive.

Abstract: Embodiments are directed to systems that build and deploy inferential models for generating predictions of a plant process. The systems select input variables and an output variable for the plant process. The systems load continuous measurements for the selected input variables. For the selected output variable, the systems load measurements of type: continuous from the subject plant process, intermittent from an online analyzer, or intermittent from lab data. If continuous or analyzer measurements are loaded, the systems build a FIR model with a subspace ID technique using continuous output measurements. From intermittent analyzer measurements, the systems generate continuous output measurements using interpolation. If lab data is loaded, the systems build a hybrid FIR model with subspace ID and PLS techniques, using continuous measurements of a reference variable correlated to the selected output variable.

Abstract: The invention provides an antenna structure comprising a plurality of wire segments formed in a loop. Connecting units are provided between the wire segments, each of which is switchable between a conductive state and a reactive state. With the connecting units in the conductive state a loop antenna is formed with a first (longer) signal range and with the connecting units in the reactive state an antenna structure is formed with a second (shorter) signal range. Said reactive state is adapted to introduce a phase delay between the adjacent wire segments. This enables the same antenna to be used for long range signal communication and short range communication, for example for system configuration or commissioning. The antenna structure may be used with luminaires of a lighting system.

Abstract: The invention relates to medicines, and more particularly to an abortion medication and an administration thereof, where the abortion medication contains 40-60 mg/mL of a kidney bean lectin. The invention also provides another abortion medication, which contains 40-60 mg/mL of a kidney bean lectin, 40-50 mg/mL of an oligosaccharide and 6-9 mg/mL of NaCl. The two abortion medications provided herein are both capable of effectively terminating the pregnancy and are safe without toxic side effects. Moreover, these drugs can be reused several times. These abortion medications are administered intrauterinely, which enables the kidney bean lectin therein to show the best abortive effect, and the local administration of these drugs in the uterine cavity has relatively simple operation.

Abstract: Disclosed herein are ion exchange membranes, electrochemical systems, and methods that relate to various configurations of the ion exchange membranes and other components of the electrochemical cell.

Abstract: In embodiments of hardware verification with RFID-stored build information, a device includes hardware components and a wireless radio tag to store build information for hardware verification of the hardware components in the device. A bootloader can interrogate the wireless radio tag to obtain the build information and compare the build information to current information of the hardware components in the device. The bootloader can then determine whether the current information matches the build information. If the current information does not match the build information, then the build information for the hardware components can be stored in the wireless radio tag, and functionality of the hardware components in the device is limited.

Abstract: Described herein are FasL-engineered biomaterials, as well as methods of making and using such FasL-engineered biomaterials, such as for immunomodulation, such as for inducing immunosuppression and specific immune tolerance, such as for preventing or reducing the risks of rejection of cellular or tissue grafts and/or the treatment of autoimmune disorders such as Type I diabetes. In specific embodiments, the FasL-engineered biomaterials are biotinylated microgels bound to SA-FasL.

Abstract: A fast charge lithium ion battery capable of being charged or discharged with 80% capacity retention at C rate of at least 2C is provided in the present invention, which includes a fast charge graphite-based anode; a cathode; and a separator, wherein the anode includes an anode current collector and a fast charge graphite layer deposited on at least one surface of the anode current collector, the fast charge graphite having a lattice constant equals to or larger than 0.3374 nm, a D-band to G-band integrated area ratio (ID/IG) of 0.03 to 0.3, and a surface morphology of a plate-like crystal structure under a scanned electron microscope; the cathode includes a cathode current collector and one or more active materials deposited on at least one surface of the cathode current collector.

Abstract: Provided is a Na—Y molecular sieve and a method for preparing the Na—Y molecular sieve, an H—Y molecular sieve and a method for preparing the H—Y molecular sieve, a hydrocracking catalyst, and a hydrocracking method. The average grain diameter of the Na—Y molecular sieve is 2-5 ?m, and the sum of pore volumes of pores in 1-10 nm diameter accounts for 70-90% of the total pore volume of the Na—Y molecular sieve. The H—Y molecular sieve obtained from the large-grain Na—Y molecular sieve can be used as an acidic component in the hydrocracking catalyst. When the hydrocracking catalyst containing the H—Y molecular sieve is applied in the hydrocracking reaction of heavy oils that contain macromolecules, it can provide better cracking activity and product selectivity in the hydrocracking reaction.