Abstract: An example electro-optical modulator includes an electrode conversion portion and an optical modulation portion. The electrode conversion portion includes a first input electrode and a second input electrode, where the first input electrode is configured to receive a first modulation signal, and the second input electrode is configured to receive a second modulation signal. The optical modulation portion includes a first modulation electrode, a second modulation electrode, a third modulation electrode, a first modulation arm, and a second modulation arm. The first modulation arm is between the first modulation electrode and the second modulation electrode, and the second modulation arm is between the first modulation electrode and the third modulation electrode. The first modulation electrode is coupled to the first input electrode, and the second modulation electrode and the third modulation electrode are separately coupled to the second input electrode.

Abstract: The present disclosure relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof. The present disclosure further relates to methods of inhibiting viral replication including contacting one or more cells that have been infected with a virus with an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the virus comprises a flavivirus. Also disclosed is a method of treating and/or preventing a flavivirus infection and/or a condition resulting from a flavivirus infection including administering an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof under conditions effective to treat and/or prevent a flavivirus infection and/or a condition resulting from a flavivirus infection.

Abstract: An array substrate and a reflective display substrate are disclosed. The array substrate includes a base, and a plurality of data lines and a plurality of sub-pixels that are disposed on the base. The sub-pixel includes a reflective pixel electrode and a TFT. An orthographic projection of the pixel electrode in each sub-pixel on the base is overlapped with orthographic projections of a first electrode, a first data line and a second data line.

Abstract: The present disclosure relates to a Prp8 intein splicing inhibitor. The present disclosure further relates to a method of treating and/or preventing a fungal infection, said method comprising administering a Prp8 intein splicing inhibitor under conditions effective to treat and/or prevent a fungal infection. Also disclosed is a method of inhibiting Prp8 intein expression or activity in a cell or tissue, said method comprising administering a compound under conditions effective to inhibit Prp8 intein expression or activity in a cell or tissue. Further disclosed are methods for screening for compounds that inhibit Prp8 intein splicing comprising an assay and a kit for predicting the likelihood of Prp8 inhibition.

Abstract: An array substrate and a reflective display substrate are disclosed. The array substrate includes a base, and a plurality of data lines and a plurality of sub-pixels that are disposed on the base. The sub-pixel includes a reflective pixel electrode and a TFT. An orthographic projection of the pixel electrode in each sub-pixel on the base is overlapped with orthographic projections of a first electrode, a first data line and a second data line.

Abstract: Provided is a method of inhibiting viral replication, including contacting one or more cells that has been infected or contacted with a flavivirus with an effective amount of niclosamide, temoporfin, nitazoxanide, tizoxanide, erythrosin B, methylene blue. Contacting one or more cells that have been infected with a flavivirus may include administering the compound to a mammal, a human, or other subject. The flavivirus may be Dengue virus serotype 1, Dengue virus serotype 2, Dengue virus serotype 3, Dengue virus serotype 4, yellow fever virus, West Nile virus, Zika virus, Japanese encephalitis virus, tick-born encephalitis virus, Powassan virus, St. Louis encephalitis virus, or other flavivirus.

Abstract: A target detection method and apparatus are provided. A first image of a target scenario collected by an image sensor is analyzed to obtain one or more first 2D detection boxes of the target scenario, and a three-dimensional point cloud of the target scenario collected by a laser sensor is analyzed to obtain one or more second 2D detection boxes of the target scenario in one or more views (for example, a BEV and/or a PV). Then, comprehensive analysis is performed on a matching degree and confidence of the one or more first 2D detection boxes, and a matching degree and confidence of the one or more second 2D detection boxes, to obtain a 2D detection box of a target. Finally, a 3D model of the target is obtained based on a three-dimensional point corresponding to the 2D detection box of the target.

Abstract: A display panel includes a driving circuit and a signal line. The signal line includes at least two main signal sub-lines each including a first end and a second end, the first ends of the at least two main signal sub-lines are electrically coupled to each other, and the second ends thereof are electrically coupled to each other. N main signal sub-lines in the at least two main signal sub-lines are directly electrically coupled to the driving circuit. Each of the N main signal sub-lines is a direct-coupled main signal sub-line, and a main signal sub-line in the at least two main signal sub-lines other than the direct-coupled main signal sub-lines is an indirect-coupled main signal sub-line which is not directly electrically coupled to the driving circuit but electrically coupled to the driving circuit via the direct-coupled main signal sub-line, where N is a positive integer.

Abstract: A display substrate is provided, including: a base (1); and a plurality of pixel units (10) located on the base (1) and arranged in an array, where the display substrate further includes a plurality of data lines (25), and for each of the plurality of data lines (25), the data line (25) extends along a column direction and is located between adjacent first pixel unit (10A) and second pixel unit (10B) in a row direction, the data line (25) is arranged in a different layer from a first pixel electrode (40A) of the first pixel unit (10A) and a second pixel electrode (40B) of the second pixel unit (10B), and the data line (25) includes a first branch line (252) and a second branch line (253) that are connected in parallel and extend in the column direction; an orthographic projection of the first branch line (252) on the base (1) at least partially overlaps with an orthographic projection of the first pixel electrode (40A) on the base (1); an orthographic projection of the second branch line (253) on the base (1)

Abstract: Provided is a method of inhibiting viral replication, including contacting one or more cells that has been infected or contacted with a flavivirus with an effective amount of niclosamide, temoporfin, nitazoxanide, tizoxanide, erythrosin B, methylene blue. Contacting one or more cells that have been infected with a flavivirus may include administering the compound to a mammal, a human, or other subject. The flavivirus may be Dengue virus serotype 1, Dengue virus serotype 2, Dengue virus serotype 3, Dengue virus serotype 4, yellow fever virus, West Nile virus, Zika virus, Japanese encephalitis virus, tick-born encephalitis virus, Powassan virus, St. Louis encephalitis virus, or other flavivirus.

Abstract: The embodiments of the present disclosure propose a shift register, a driving method thereof, a gate driving circuit and a display apparatus. The shift register comprises an input sub-circuit coupled to an input terminal and a pull-up node, and configured to charge the pull-up node under control of an input signal from the input terminal; an output sub-circuit coupled to a clock signal terminal, the pull-up node, and an output terminal, and configured to transmit a clock signal from the clock signal terminal to the output terminal under control of the pull-up node; and an output shaping sub-circuit coupled to the clock signal terminal, the output terminal, and a first voltage signal terminal, and configured to transmit a first voltage signal from the first voltage signal terminal to the output terminal under control of the clock signal.

Abstract: Provided is an array substrate including: a base substrate, a plurality of pixel units and a plurality of touch signal lines that are arranged on the base substrate. At least one pixel unit includes a plurality of sub-pixels. Two touch signal lines are arranged in the pixel unit, and the two touch signal lines are located on a side of a data line connected with one sub-pixel of the pixel unit.

Abstract: The present disclosure provides a shift register including: a pre-charge reset circuit and an output circuit, the pre-charge reset circuit is configured to write, in a pre-charge stage, an input signal in an active level state into the pull-up node in response to the control of a first control signal, and write, in a reset stage, an input signal in an inactive level state into the pull-up node in response to the control of a second control signal; the output circuit is configured to write, in an output stage, a clock signal in an active level state into a signal output terminal in response to the control of an electric signal in an active level state at the pull-up node, and write, in the reset stage, a clock signal in an inactive level state into the signal output terminal in response to the control of the second control signal.

Abstract: An array substrate and a reflective display substrate are disclosed. The array substrate includes a base, and a plurality of data lines and a plurality of sub-pixels that are disposed on the base. The sub-pixel includes a reflective pixel electrode and a TFT. An orthographic projection of the pixel electrode in each sub-pixel on the base is overlapped with orthographic projections of a first electrode, a first data line and a second data line.

Abstract: The present disclosure is related to a shift register circuit. The shift register circuit may include a shift output circuit and N driving output circuits. N is an integer larger than 1. Among the N driving output circuits, an i-th driving output circuit may be respectively coupled to an i-th driving clock signal terminal of N driving clock signal terminals, a pull-up node of the shift output circuit, and an i-th driving output terminal of N driving output terminals. The i-th driving output circuit may be configured to input an i-th driving clock signal from the i-th driving clock signal terminal to the i-th driving output terminal under a control of the pull-up node, wherein i is a positive integer not greater than N.

Abstract: Discloses are a display panel, a method of manufacturing the same and a display device. The display panel includes: a first substrate; a second substrate disposed opposite to the first substrate; and a reflective structure group disposed on the first substrate, the reflective structure group includes a plurality of reflective structures in one-to-one correspondence with visual fields of view, and a reflective surface of each reflective structure of the reflective structures faces the second substrate, and the reflective structure is configured to reflect light from the second substrate in a predetermined direction to a corresponding field of view.

Abstract: A pixel circuit includes a data written-in sub-circuit, a driving sub-circuit, a threshold compensation sub-circuit, a light-emitting element, a sensing sub-circuit and a first light-emission control sub-circuit. The driving sub-circuit is configured to control a driving current for driving the light-emitting element to emit light. The data written-in sub-circuit writes threshold compensation information into a second terminal of the driving sub-circuit at a compensation stage. The threshold compensation sub-circuit stores a data signal and adjusts a voltage at the second terminal of the driving sub-circuit in a coupled manner. The sensing sub-circuit writes a sensing voltage into a first terminal and the second terminal of the driving sub-circuit at a display process, senses aging information of the light-emitting element during an aging detection process and transmits the aging information to the aging detection device.

Abstract: A shift register unit, a driving method thereof, a gate drive circuit and a display device are provided. The shift register unit includes: an input circuit, an output circuit, a pull-down control circuit and a pull-down circuit; and the output circuit is connected to a first DC power supply terminal, a second clock signal terminal, a pull-up node, a first driving signal output terminal and a second driving signal output terminal respectively, and is configured to output a first power supply signal of the first DC power supply terminal to the first driving signal output terminal under control of the pull-up node.

Abstract: Embodiments of the present disclosure provide a touch display substrate, a method for manufacturing the same, a driving method thereof, and a display device thereof. The touch display substrate includes a substrate, a plurality of electrode blocks, independent of each other and arranged in an array, disposed on the substrate, and a switching device disposed between the adjacent electrode blocks. The electrode block is configured to receive a common voltage during a display period and receive a touch scan signal during a touch period. The switching device is configured to electrically connect the adjacent electrode blocks during the display period and electrically isolate the adjacent electrode blocks from each other during the touch period.