Abstract: A spherical joint includes a body portion and a blocking portion. The body portion includes a ball portion and a joint portion. The ball portion and the joint portion have an inner surface that links the two portions together in an axial direction and an outer surface opposite to the inner surface. The outer surface of the ball portion includes a spherical surface. The body portion further includes a first section and a second section. Each of the first section and the second section intersects with the inner surface and the outer surface such that the two sections together define a gap. The blocking portion is detachably connected to the body portion and shaped to match the gap, so that the blocking portion blocks the gap to form a hollow spherical joint structure. Further disclosed in the present application are a spherical joint assembly and an ultrasonic imaging device.

Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.

Abstract: Antibodies binding to human claudin 18.2 (CLDN 18.2) and bispecific antibodies binding to both human CLDN 18.2 and PD-L1, pharmaceutical compositions comprising such, and methods of using such for treating target diseases such as cancer.

Abstract: A dimming assembly includes a first prism having a first surface and a second surface opposite to each other, and a second prism disposed on a side where the second surface of the first prism is located. The first surface includes first dimming portions, each of which includes two first side surfaces. Edges of the two first side surfaces away from the second surface intersect at a first intersection line. A surface of the second prism proximate to the second surface includes second dimming portions, each of which includes two second side surfaces. Edges of the two second side surfaces proximate to the second surface intersect at a second intersection line. A distance between orthographic projections of two adjacent first intersection lines on the second surface is less than a distance between orthographic projections of two adjacent second intersection lines on the second surface.

Abstract: A quick-release assembly includes an installation main body and a quick-release clamping plate, the installation main body is provided with a groove structure, the groove structure is provided with a first clamping hole and a second clamping hole that are oppositely arranged, and a portion of the second clamping hole is located on a side wall of the groove structure; the quick-release clamping plate matches the groove structure, and a first clamping hook and a second clamping hook are provided on the quick-release clamping plate; the installation main body is provided with a sliding block installed on the installation main body in a sliding manner; an elastic member for providing a driving force for the sliding block is also arranged in the installation main body; and a quick-release button for releasing a locking state of the sliding block is also arranged in the installation main body.

Abstract: Provided are an ultrasonic scanning control device and method, and an ultrasonic imaging system. According to an embodiment, the method includes: controlling a scanning assembly to apply an initial pressure to a tissue to be scanned of an subject; obtaining first ultrasonic images at different initial pressures; determining a pressure range on the basis of the first ultrasonic images obtained at the different initial pressures; determining, within the pressure range, a pressure applied by the scanning assembly to the tissue to be scanned during ultrasonic diagnostic scanning; and performing ultrasonic diagnostic scanning on the tissue at the determined pressure within the pressure range.

Abstract: A scanning assembly for an ultrasonic imaging device and the ultrasonic imaging device are provided in the present disclosure. The scanning assembly comprises: an ultrasonic transducer configured to send/receive an ultrasonic signal; a frame connected to an ultrasonic imaging device body; a lower housing comprising a hollow cavity having an upper open end and a lower open end, wherein the upper open end is detachably connected to the bottom of the frame, and the ultrasonic transducer is at least partially accommodated in the hollow cavity; and a film assembly detachably connected to the lower open end. The ultrasonic imaging device comprises the ultrasonic imaging device body. The ultrasonic imaging device body comprises a main device, a display, an adjustable arm, and the above scanning assembly connected to one end of the adjustable arm.

Abstract: A light guide structure and a display device are provided. The light guide structure includes: a first substrate including at least one first through hole; a second substrate arranged opposite to the first substrate and including at least one second through hole; and at least one fiber bundle including a first end and a second end, the first end of each of the fiber bundle fixed in one of the first through holes, and the second end of the fiber bundle is a free end; wherein a distance between the first substrate and the second substrate is adjustable; and an orthogonal projection of at least part of the first through hole on the second substrate coincides with the second through hole.

Abstract: A light guide structure and a display device are provided. The light guide structure includes: a first substrate including at least one first through hole; a second substrate arranged opposite to the first substrate and including at least one second through hole; and at least one fiber bundle including a first end and a second end, the first end of each of the fiber bundle fixed in one of the first through holes, and the second end of the fiber bundle is a free end; wherein a distance between the first substrate and the second substrate is adjustable; and an orthogonal projection of at least part of the first through hole on the second substrate coincides with the second through hole.

Abstract: The invention provides novel neuroactive steroids and pharmaceutical compositions thereof, as well as methods of their preparation and use, in therapy of various diseases and conditions, for example, various neurological or brain diseases.

Abstract: A light guide plate, a manufacturing method thereof, and a display device are provided. The light guide plate includes a glass substrate, an adhesive layer arranged at a surface of the glass substrate, a reflector arranged at a surface of the adhesive layer away from the glass substrate, and a total reflection structure distributed in the adhesive layer.

Abstract: A backlight module comprising a light source and a light guide plate. The light guide plate comprises a transparent substrate and a plurality of dimming units having a reflecting function. The light source is disposed on at least one side of said transparent substrate, and the plurality of dimming units is disposed on a lower surface of the transparent substrate for adjusting an emergent intensity of light, which is incident from the light source into the light guide plate, on an upper surface of said transparent substrate facing away from said dimming units. A method for controlling a backlight module and a display screen and wear device including the backlight module are also disclosed.

Abstract: A light guide plate, a manufacturing method thereof, and a display device are provided. The light guide plate includes a glass substrate, an adhesive layer arranged at a surface of the glass substrate, a reflector arranged at a surface of the adhesive layer away from the glass substrate, and a total reflection structure distributed in the adhesive layer.

Abstract: The present disclosure provides a light homogenizing structure, a front light source and a display device. The light homogenizing structure comprises a transparent substrate and a plurality of light homogenizing units arranged on a surface of the transparent substrate facing the display panel; wherein a surface of each of the light homogenizing units away from the transparent substrate is a reflective surface tilted relative to the transparent substrate, light rays emitted from the light-emitting unit facing a light entry surface of the light homogenizing structure are incident into the display panel after being reflected on the reflective surface, the light entry surface is other than a surface of the light homogenizing structure facing the display panel and its opposite surface, and an orthographic projection of one of the light homogenizing units on the display panel is located on a border between pixels of the display panel.

Abstract: A hollow fabric is obtained by providing cotton blended yarns and alkali-soluble polyester yarns which are arranged in a ratio of 10:2 as warp yarns, and providing cotton blended elastic yarns and alkali-soluble polyester filaments which are arranged in a ratio of 6:2 as weft yarns. The warp yarns and weft yarns are interwoven into plain weaves, and the plain weaves are subjected to alkali solution to remove the alkali-soluble polyester filaments, thereby obtaining greige cloth having meshes. The greige is subjected to boiled bleaching, softening and drying to obtain the hollow fabric. By optimizing the ratio of yarns and using a boiled bleaching, softening and drying process, a soft, smooth and fluffy product is produced with humidity-absorbing and breathability characteristics.

Abstract: The present disclosure relates to the field of display technology, particularly, discloses a backlight assembly and a display device. The backlight assembly includes a light guide plate and a light source. The light guide plate has a first light exiting surface and a second light exiting surface opposite to each other, and a light incident side intersecting with the first light exiting surface and the second light exiting surface. The light source is located at the light incident side of the light guide plate. The light guide plate has a refractive index which decreases first and then increases in a vertical direction from the first light exiting surface to the second light exiting surface.

Abstract: The embodiments of the present disclosure provide an optical assembly and a liquid crystal display device using the optical assembly. The optical assembly has a simple structure and low cost, and can realize a high color gamut display. The optical assembly comprises a first substrate layer, a second substrate layer, and an optical fiber layer arranged between the first substrate layer and the second substrate layer. The optical fiber layer is composed of a plurality of optical fibers arranged closely in a single layer. A plurality of adhesive blocks in contact with the plurality of optical fibers are arranged on a surface of at least one of the first substrate layer and the second substrate layer. At the contact regions between the adhesive blocks and the plurality of optical fibers, total internal reflection in the optical fibers is inhibited by the adhesive blocks.

Abstract: This disclosure provides methods for generating functionalized nanoswitches, as well as the functionalized nanoswitches themselves, and methods of use thereof.

Abstract: The present invention relates to aminotetraline and aminoindane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline and aminoindane derivatives, and the use of such aminotetraline and aminoindane derivatives for therapeutic purposes. The aminotetraline and aminoindane derivatives are GlyT1 inhibitors.

Abstract: The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.