Abstract: The present invention relates to 4,5-dihydropyrazole derivatives of the formula (I) and physiologically tolerated salts thereof which are GlyT1 inhibitors. The invention further relates to pharmaceutical compositions comprising such 4,5-dihydropyrazole derivatives, and the use of such 4,5-dihydropyrazole derivatives for therapeutic purposes.

Abstract: The present invention provides a touch system and a display device, belongs to the technical field of display, and can solve the problem that misoperation is caused as an existing touch screen has a narrow frame and the edge area of the screen is easy to touch mistakenly. The touch system comprises a touch screen, a touch position analysis unit and a switch unit, wherein the touch screen comprises a center touch area and an edge touch area, and the touch position analysis unit is used for analyzing a position of a touch on the touch screen; and the switch unit is used for controlling whether a touch on the edge touch area is effective.

Abstract: The present invention provides a backlight and a display device. The backlight includes a frame and an optical film set including a plurality of optical films that are successively stacked. Each optical film in the optical film set includes a film body and an ear part. In any two adjacent optical films, the boundary of at least one side of the ear part of the lower optical film extends beyond the boundary of the same side of the ear part of the upper optical film. A fixing member covers the ear parts of the plurality of optical films, such that the optical film set is fixed on the frame, and the fixing member can fix the relative positions among the plurality of optical films in the optical film set. In the backlight, the optical film set is reliably fixed without affecting the normal display on the display device.

Abstract: The present invention discloses a display device with multiple display surfaces, including: a multi-surface display structure including at least two display panels; a light source provided under the middle part of the display structure; and a reflective surface including at least two reflectors having inclination angles is arranged on the top of the multi-surface display structure. The light source is provided under the multi-surface display structure, such that the bottom space of the display device is efficiently utilized, and the light shadow is eliminated. Therefore, the display performance is improved. The curved reflective surface provided on the top of the multi-surface display structure can reflect the light emitted from the light source, such that the light emergent from each display panel is uniform. The light energy is efficiently utilized (i.e., the utilization of the light source is increased). Thus, the purpose of energy-saving is achieved.

Abstract: The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I) wherein R1, R2, R3, R4, R5, A, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.

Abstract: A dimming unit, a backlight module group and a display device are disclosed in the disclosure. The dimming unit according to the disclosure includes a dimming body and a light source, a groove is provided on the dimming body, a cavity is provided on a first sidewall of the groove for accommodating the light source, and the cavity has a light outlet facing a second sidewall of the groove which is opposite to the first sidewall, so that a light ray is reflected by the second sidewall towards an opening of the groove. A backlight module group includes an optical film layer and a light source device provided on a side of a light incident surface of the optical film layer, the light source device includes the dimming unit according to the disclosure, and a light ray emitted by the dimming unit is emitted to the optical film layer.

Abstract: The present invention relates to aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives of the formula (I) or a physiologically tolerated salt thereof The invention relates to pharmaceutical compositions comprising such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, and the use of such aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquin oline derivatives for therapeutic purposes. The aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives are GlyT1 inhibitors.

Abstract: The present invention relates to aminotetraline and aminoindane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline and aminoindane derivatives, and the use of such aminotetraline and aminoindane derivatives for therapeutic purposes. The aminotetraline and aminoindane derivatives are GlyT1 inhibitors.

Abstract: The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I) wherein R1, R2, R3, R4, R5, A, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.

Abstract: The present invention provides an apparatus for manufacturing semiconductor wafer comprising at least two manipulators, at least one set of chemical gas/liquid distribution unit and an air circulating and filtering unit. The air circulating and filtering unit is separated into three regions, including the front region, the middle region, and the side region, which are controlled by respective control electric motors to achieve uniform air flow and uniform pressure in the respective regions. The cleaning degree in the internal of the apparatus can be improved by the regional control of the air circulating and filtering unit; the wafer transport efficiency can be enhanced by the double-armed manipulators having multiple degrees of freedom; and the product yield per unit area can be increased by the chemical gas/liquid distribution unit providing stable and uniform gas/liquid flow and pressure.

Abstract: The present invention provides an apparatus for manufacturing semiconductor wafer comprising at least two manipulators, at least one set of chemical gas/liquid distribution unit and an air circulating and filtering unit. The air circulating and filtering unit is separated into three regions, including the front region, the middle region, and the side region, which are controlled by respective control electric motors to achieve uniform air flow and uniform pressure in the respective regions. The cleaning degree in the internal of the apparatus can be improved by the regional control of the air circulating and filtering unit; the wafer transport efficiency can be enhanced by the double-armed manipulators having multiple degrees of freedom; and the product yield per unit area can be increased by the chemical gas/liquid distribution unit providing stable and uniform gas/liquid flow and pressure.

Abstract: The present invention relates to efficient synthetic method of 1,3,5-tris (N-Phenylbenzimidazole) Benzene and pertains to the field of synthesis of organic light-emitting materials. The method and process of the patent are as following: 1,3,5-tris (N-Phenyl-N Phenylammonium) Benzamide is treated by shrinking agent but no high temperature required, and then high purity product can be reached after raw material dissolved. The reaction only takes a few minutes and through recrystallization the purity can be over 99%, and then the material with stable crystal phase reached after sublimation step. The method introduced by the present patent is easy to operate, and with high in yield and purity, which adapt industrial production and has important significance for the industrialization.

Abstract: A synthetic method for preparing organometallic iridium compounds is provided and includes the two steps of (1) synthesizing a di-iridium compound with a halogenated bridge: L2Ir(??X)2IrL2, L; and (2) reacting L2Ir(??X)2IrL2 with a ligand to give the product [C?]N]2Ir (LX). The invention is an improvement over the traditional method for preparing such compounds and has the advantages of shortened reaction time, increased yield, and products of over 99% purity obtained without chromatography.

Abstract: The present invention relates to Aromatic ring substituted dianthracene compounds and pertains to the field of synthesis of organic light-emitting materials. Aromatic ring substituted dianthracene compounds in the formula (I) present high glass transition temperature and solution efficiency, which can be used as effective blue-light emitting host materials.

Abstract: This invention, which belongs to the field of organic synthesis, involves “One-step synthetic method of 2,9-dimethyl-1,7-diphenyl-1,10-phenanthroline”. This method uses O-phenylenediamine and formula III to react under the condition of mixed-shrinking agent, the synthesis can be completed in one step, the stated mixed-shrinking agent is mixture of hydrochloric acid and organic acid. The organic acid serves as phase transfer catalyst and shrinking agent, meanwhile, as buffer reagent, organic acid reduces polymerization of III, and side products as well. The products gained are of high purity and the reaction is mild and easy to control. Since there is no polluting material added and generated, the waste is safe to discharge. In the after treatment of reaction, ketone solvent is used to reduce separation step and product lost, thus improving yield.

Abstract: Disclosed are methods and compositions of assessing one or more statuses of a subject. Also disclosed are methods and compositions of identifying status biomarkers associated with a status of a subject. Also disclosed are sets of one or more status biomarkers. Also disclosed are methods and compositions of producing status biomarker capture probes.

Abstract: This invention, which involves “the preparation method of 8-hydroxyquinoline metallic compound”, is a synthetic method of organic electroluminescent materials. The preparation method of compound Mqnqm? is to add solution prepared by Zengshui solvent and industrial ligand into reaction vessel, stir it at a certain temperature, and then achieve high-purity product, as for the Mqnqm?, M stands for Al, Li, n stands for 1-3, m is 0-2, q is 8-hydroxyquinoline and its derivatives, and q? is ligand different from q. Zengshui solvent is adopted in this invention which can react effectively and thus reducing reaction time and avoiding cumbersome operation and the refining process; this invention also increases total yield and purity, the mother liquor obtained can be recycled, which reduces environment pollution and cost as well.

Abstract: This invention, which involves synthetic method of 5, 5- dimethyl-2, 4-adipaldehyde-0, 0-Boron difluoride, belongs to the field of organic synthesis. Synthetic method of 5, 5-dimethyl-2, 4-adipaldehyde-0, 0-Boron difluoride is to react pinacolone and boron trifluoride diethyl ether at low temperature, and then add aqueous alkaline solution in after treatment to extract product from ether, after that, separate fluid, condense organic phase and final product is obtained. Yield of this method is 2 to 3 times higher than that in literature, and apart from that, mild reaction condition, simple procedures, easy operation, and low cost make it easy for industrial production. The product can be used directly in next step reaction without any special purification.

Abstract: This invention, which belongs to the field of organic electroluminesent materials synthetic technology, involves synthetic method of 10,10?-Dibromo-9,9?-bianthryl. The synthetic method is to use 9,9?-bianthryl as raw material, chlorinated hydrocarbon as solvent, bromide as bromine agent and react. This method not only produces no environmental pollution, but also enjoys high yield, therefore, it is suitable for industrial production.

Abstract: This invention, which involves “the synthetic method of 9, 9?-biantnthracine”, belongs to the field of synthetic technology of organic electroluminesent materials. Synthetic method of 9, 9?-bianthracine is to add anthraquinone as raw material and zinc as reducing agent in glacial acetic acid solution, then batch addition of hydrochloric acid at 70-120°, maintain the temperature unchanged and react, then 9, 9?-bianthracine is achieved. This invention uses one-step method to synthesize 9, 9?-bianthracine, which reduces not only cost but also generation of side products, in addition, the products obtained need no purification and can be directly used to synthesize related similar compounds, therefore, it is very suitable for large-scale industrial production.