Abstract: A side-firing laser system with a standoff catheter includes an optical fiber configured to emit therapeutic laser radiation in a direction generally transverse to an axis of the fiber; and a catheter through which the optical fiber is inserted during a surgical procedure. The catheter includes a transparent end section through which the therapeutic laser radiation passes to vaporize tissue outside the catheter, an open distal end to permit exit of irrigation fluid from the catheter, and an opening in a side of the end section, the opening having dimensions that are approximately equal to or less than cross-sectional dimensions of the therapeutic laser radiation. When the fiber is moved to a position at which the therapeutic laser radiation passes through the opening, the laser radiation causes coagulation or vaporization of tissues.

Abstract: A turbocharger shaft includes a connection portion at a connection with a wheel of the turbocharger. The shaft includes a stainless steel cladding at least along one or more grooves of the connection portion to reduce the risk of cold cracking and bending fatigue.

Abstract: A multi-layer device comprising a first substrate and a first electrically conductive layer on a surface thereof, the first electrically conductive layer having a sheet resistance to the flow of electrical current through the first electrically conductive layer that varies as a function of position.

Abstract: A system and method for manufacturing a space-based component in space. The method includes collecting and capturing space debris directly from and suspended in space, heating the collected space debris using solar radiation in a manner that separately and independently melts different constituent elements and compounds in the space debris, collecting the different constituent elements and compounds as they are being separately melted, storing the elements and compounds in a molten, solid or vapor form, and fabricating the space-based component using the stored elements and compounds.

Abstract: A wirelessly powered inflatable medical implant system includes a medical provider software application, a patient external controller and a MR-Conditional, nonferrous pump in reservoir implant. The medical provider software application programs the patient external controller for the patient to transmit wireless power and control signals to circuitry in a pump in reservoir implant. In response, the pump in reservoir implant, containing a fluid reservoir and pump package submerged therein, transfers fluid from the reservoir through tubing, and into one or more inflatable medical implants. Submerging the pump package within the reservoir simplifies surgery in males and pump placement in females and provides pump package heatsinking to limit implant overheating.

Abstract: A multi-layer device comprising a first substrate, a first electrically conductive layer and a first current modulating structure on a surface thereof, the first current modulating structure comprising a composite of a resistive material and a patterned insulating material, the first current modulating structure having a cross-layer resistance to the flow of electrical current through the first current modulating structure that varies as a function of position.

Abstract: An ophthalmic technician is present with a patient in an exam room to operate eye examination equipment and transmit patient information to remote location. At that remote location, a skilled technician is present to provide the necessary optical care, and may operate the phoropter from the remote location. Using video and/or teleconferencing equipment and a phoropter located in the patient examination room along with management software, the system works to determine the final optical prescription for the patient. That information, coupled with findings from other devices which are integrated with the management software, and that the patient uses locally, are reviewed by a remote-based optometrist or ophthalmologist.

Abstract: A device includes a carriage movable relative to a build pad along a bi-directional travel path and supporting at least a radiation source and an applicator to selectively apply a plurality of fluid agents, including first fluid agents to affect a first material property. A timing and order of operation of the radiation source and the applicator, with the carriage, is to maintain first and second portions of a 3D object under formation within at least one selectable temperature range despite a first total volume of the first fluid agents for application onto the first portion of the 3D object being substantially greater than a second total volume of second fluid agents for application onto the second portion of the 3D object.

Abstract: An example of a fusing agent includes a metal bis(dithiolene) salt, a polar aprotic solvent, and a balance of water. An example of a method for making an example of the fusing agent includes adding a metal bis(dithiolene) salt into a liquid vehicle including at least a polar aprotic solvent and water.

Abstract: In one example, a lighting device for an additive manufacturing machine includes first light sources each to emit monochromatic light within a first band of wavelengths that includes a peak light absorption of a liquid coalescing agent and second light sources each to emit monochromatic light within a second band of wavelengths different from the first band of wavelengths. Each of the first light sources or each of multiple groups of the first light sources is individually addressable to emit monochromatic light independent of any other of the first light sources or of any other group of the first light sources and each of the second light sources or each of multiple groups of the second light sources is individually addressable to emit monochromatic light independent of any other of the second light sources or of any other group of the second light sources.

Abstract: A system and method for vaporizing space debris in space. The system includes a spacecraft body, a primary solar concentrator mounted to the spacecraft body that collects and focuses solar flux from the sun, and a secondary solar concentrator positioned at a focal point of the primary solar concentrator that refocuses the focused solar flux. A manipulator arm coupled to the spacecraft body grabs the space debris in space and positions it at a location where the refocused solar flux vaporizes the debris. The secondary solar concentrator can be a point-source concentrator, the primary solar concentrator can be a parabolic mirror, a Fresnel lens or a light focusing element or assembly, and the space debris can be a retired spacecraft or launch vehicle upper stage or component.

Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R3a, R4, R5, R6, R7, R8 and the subscript n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: In one example, a lighting device for an additive manufacturing machine includes an array of light sources each to emit monochromatic light within a band of wavelengths that includes a peak light absorption of a liquid coalescing agent to be dispensed on to a build material.

Abstract: The present application pertains to family of new crystalline molecular sieves designated SSZ-92. Molecular sieve SSZ-92 is structurally similar to sieves falling within the ZSM-48 family of molecular sieves and is characterized as having magnesium.

Abstract: Provided herein are salt forms of a complement component 5a receptor having the formula of Compound 1 Also provided herein are pharmaceutical compositions and methods of treatment using the salt forms of Compound 1, described herein.

Abstract: An example of a fusing agent includes a metal bis(dithiolene) salt, a polar aprotic solvent, and a balance of water. An example of a method for making an example of the fusing agent includes adding a metal bis(dithiolene) salt into a liquid vehicle including at least a polar aprotic solvent and water.

Abstract: A protective structure for the distal treatment end of a surgical laser fiber inserted into a patient through a scope includes uniformly-spaced ruler or scale markings that are visible through the scope and that enable the size of an object within the field of view of the scope to be precisely determined.

Abstract: Apparatus and methods for making metal-connected particle articles. A metal containing fluid is selectively applied to a layer of particles. The metal in the fluid is used to form metal connections between particles. The metal connections are formed at temperatures below the sintering temperature of the particles in the layer of particles.