Abstract: A three-dimensional printing build material composition includes a polymer particle, and a radiation absorbing additive mixed with the polymer particle. The radiation absorbing additive has a particle size ranging from about 1 ?m to about 100 ?m, and the radiation absorbing additive is to absorb incident radiation having wavelengths ranging from 700 nm to 10 ?m.

Abstract: Compounds represented by Formula (I) or (II): are provided herein, or a pharmaceutically acceptable salt, or a prodrug or bioisostere thereof; wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R2a?, R2b?, R2c?, R3?, R4?, R5?, R6a?, Y, Y?, and the subscripts m and n are as defined herein.

Abstract: The present disclosure is drawn material sets, coalescent fluids, and 3-dimensional printing systems. An example material set can include an amorphous polymer powder having an average particle size from 1 micron to 300 microns, and a coalescent fluid including a viscosity reducing agent.

Abstract: The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.

Abstract: Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R3a, R4, R5, R6, R7, R8 and the subscript n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: A multi-layer device comprising a first substrate and a first electrically conductive layer on a surface thereof, the first electrically conductive layer having a sheet resistance to the flow of electrical current through the first electrically conductive layer that varies as a function of position.

Abstract: In an example of a three-dimensional (3D) printing method, a polymeric or polymeric composite build material is applied. A fusing agent is selectively applied on at least a portion of the polymeric or polymeric composite build material. The fusing agent includes a discolorable near-infrared absorbing dye, a thiol surfactant, a reducing agent, and a balance of water. Near-infrared radiation is applied to the polymeric or polymeric composite build material at a condition that maintains a temperature of the selectively applied fusing agent below a decomposition temperature of the fusing agent and that allows the discolorable near-infrared absorbing dye to harvest near-infrared radiation energy, in order to fuse the portion of the polymeric or polymeric composite build material in contact with the fusing agent to form a layer and to initiate discoloration of the discolorable near-infrared absorbing dye in the layer.

Abstract: The invention provides coated substrates comprising a substrate and a barrier coating on at least one surface of the substrate. The barrier coating comprises (i) vermiculite, (ii) polymer capable of forming a film, (iii) chemical stabilizing agent selected from materials that contain cationic functionality selected from lithium, alkyl C2-C6 ammonium, allyl ammonium, heterocylclic ammonium, morpholonium, ammonium and amino C3-C6 alkyl carboxylic acids; lithium cations in combination with anions selected from carboxylic, phosphoric, phosphonic, sulfonic and fatty acids, lithium chelating agents, and lithium salts, ammonia, C3-C6 amine, heterocyclic amines, lithium hydroxide, morpholine, and morpholine oleate; and (iv) cross-linking agent. The invention also provides articles coated with such coatings, methods and mixtures for making such coated substrates and articles.

Abstract: An ophthalmic technician is present with a patient in an exam room to operate eye examination equipment and transmit patient information to remote location. At that remote location, a skilled technician is present to provide the necessary optical care, and may operate the phoropter from the remote location. Using video and/or teleconferencing equipment and a phoropter located in the patient examination room along with management software, the system works to determine the final optical prescription for the patient. That information, coupled with findings from other devices which are integrated with the management software, and that the patient uses locally, are reviewed by a remote-based optometrist or ophthalmologist.

Abstract: A multi-layer device comprising a first substrate, a first electrically conductive layer on a surface thereof, and a first current modulating layer, the first electrically conductive layer having a sheet resistance to the flow of electrical current through the first electrically conductive layer that varies as a function of position.

Abstract: The present disclosure is drawn to material sets for 3D printing and methods of 3D printing. The material set can include a coalescent an organic-soluble near-infrared dye having a peak absorption wavelength from 800 nm to 1400 nm. The coalescent ink can also include water and an organic co-solvent. The material set can also include a particulate polymer formulated to coalesce when contacted by the coalescent ink and irradiated by a near-infrared energy having the peak absorption wavelength.

Abstract: An ophthalmic technician is present with a patient in an exam room to operate eye examination equipment and transmit patient information to remote location. At that remote location, a skilled technician is present to provide the necessary optical care, and may operate the phoropter from the remote location. Using video and/or teleconferencing equipment and a phoropter located in the patient examination room along with management software, the system works to determine the final optical prescription for the patient. That information, coupled with findings from other devices which are integrated with the management software, and that the patient uses locally, are reviewed by a remote-based optometrist or ophthalmologist.

Abstract: A method for controlling an electrochromic device is provided. The method includes applying a constant supply current to the electrochromic device and determining an amount of charge transferred to the electrochromic device, as a function of time and current supplied to the electrochromic device. The method includes ceasing the applying the constant supply current, responsive to a sense voltage reaching a sense voltage limit and applying one of a variable voltage or a variable current to the electrochromic device to maintain the sense voltage at the sense voltage limit, responsive to the sense voltage reaching the sense voltage limit. The method includes terminating the applying the variable voltage or the variable current to the electrochromic device, responsive to the determined amount of charge reaching a target amount of charge.

Abstract: Embodiments of the present disclosure include a system for anchoring implantable medical devices to bones. It includes an implantable medical device such as an inflatable penile prosthesis, a sliding edge clamp for anchoring at least partially around a bone, and a prosthesis receptacle coupled to the sliding edge clamp and extending outwardly and positioned to receive the prosthesis.

Abstract: An example of a fusing agent includes a metal bis(dithiolene) complex, a thiol surfactant, a polar aprotic solvent, and a balance of water. In an example of a method of making the fusing agent, the metal bis(dithiolene) complex is exposed to an aqueous solution including a reducing agent and a thiol surfactant to form a reduced metal bis(dithiolene) complex and to dissolve the reduced metal bis(dithiolene) complex in the aqueous solution. The aqueous solution is incorporated into a vehicle including a water soluble organic solvent and an additive selected from the group consisting of an emulsifier, a surface tension reduction agent, a wetting agent, a scale inhibitor, an anti-deceleration agent, a chelating agent, an antimicrobial agent, and a combination thereof. The fusing agent may be utilized in a three-dimensional printing method and/or incorporated into a three-dimensional printing system.

Abstract: The present disclosure is drawn to coalescent inks and material sets for 3D printing. The coalescent ink can include an organic-soluble near-infrared dye having a peak absorption wavelength from 800 nm to 1400 nm. The coalescent ink can also include water and an organic co-solvent.

Abstract: In one example, a non-transitory processor readable medium with instructions thereon that when executed cause an additive manufacturing machine to partially or completely bury a part in layers of molten build material.

Abstract: An earplug for blocking sound and method of making the same, which includes a planar insert within an earplug of compressible slow recovery foam. A method of attenuating sound by inserting the earplug at an ear canal entry so that the planar insert is tactilely vertical, and pushing the earplug into the ear canal allowing the earplug to flex perpendicular to plana surfaces of the planar insert.

Abstract: A hand-held spreader is provided having a housing with a compartment for particulate material, a chamber below the compartment having a bottom wall with a circular aperture, an impeller mounted for rotation in the chamber along such bottom wall responsive to a hand crank, a discharge opening, and a path along which the particulate material passes into the chamber for discharge via the discharge opening. The impeller has an outer circular periphery proximal to and extending over an outer edge of the aperture to form a gap between the impeller and the bottom wall of the chamber that seals the gap from the particulate material larger than the gap from entering under the impeller and risking obstruction of impeller rotation. Any particulate material that enters the gap passes downward through the aperture to enable self-cleaning of particulate material that would otherwise collect under the impeller in the chamber.