Abstract: Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula (I) are as set out in the description.

Abstract: A method of continuously manufacturing organometallic compounds is provided where two or more reactants are conveyed to a reactor having a laminar flow contacting zone, a heat transfer zone, and a mixing zone having a turbulence-promoting device; and causing the reactants to form the organometallic compound.

Abstract: The present invention relates generally to the field of food and beverages. In particular, the present invention relates to a powdered beverage comprising fruit or vegetable pulp. Embodiments of the present invention relate to compositions comprising dry fruit or vegetable pulp and sugar powder wherein the sugar is at least partially embedded in the pores of the pulp cell structure and wherein the size of the pulp particles is selected in a way that, e.g., segregation of low density pulp particles is avoided during transportation and storage time.

Abstract: A device comprising an electrostatic discharge protection structure (8), an ion sensitive field effect transistor (ISFET) having a floating gate (5,6,7,9,10), and a sensing layer (12) located above the floating gate. The device is configured such that the electrical impedance from the sensing layer to the electrostatic discharge protection structure is less than the electrical impedance from the sensing layer to the floating gate. The device can be fabricated in a standard CMOS process.

Abstract: Phenyl propanoic acid compounds having activating effect on peroxisome proliferator-activated receptors (PPAR?,?,?) and a preparation method and uses thereof are provided in the present invention. The compounds can be used for treating or preventing diseases associated with peroxisome proliferator-activated receptors (PPAR?,?,?).

Abstract: The present invention relates generally to the field of food and beverages. In particular, the present invention relates to a powdered beverage comprising fruit or vegetable pulp. Embodiments of the present invention relate to compositions comprising dry fruit or vegetable pulp and sugar powder, wherein the size of the sugar powder particles and pulp particles is selected in a way that, e.g., segregation of low density pulp particles is avoided during transportation and storage time.

Abstract: This disclosure relates to a static mixer (1) with a plurality of nozzles, and more generally, to a mixer and method of use thereof for mixing phosgene and amine with shaped jets or at least two rows of nozzles (15,16)where the second row (16) is used to enrich an area of deficit of the phosgene flow within the static reactive jet mixer (1). Configurations of enriching secondary flow include the use of concentric, eccentric, or offset jets of amine/phosgene, and the use of nozzles with different and regular geometries to help focus amine/phosgene to a specific area of the principal phosgene flow.

Abstract: The present invention provides N-methylethylcarbamino-3-[(S)-1-(methyl-[(S)-1-phenylethyl]amino)ethyl]phenyl ester represented by formula (II) and its preparation method. The present invention also provides (S)-1-(3-methoxyphenyl)-N-methyl-N—[(S)-1-phenylethyl]ethylamine and 3-[(S)-1-(methyl-[(S)-1-phenylethyl]amino)ethyl]phenol as intermediates of the compound represented by formula (II), and the use of the compound represented by formula (II) for preparing rivastigmine used for treating Alzheimer disease.

Abstract: Processes for producing a suitable purity grade of L-Citrulline are disclosed. The processes can include contacting crude L-Citrulline in an aqueous solution with an adsorptive medium at a temperature above approximately 50° C. and below the temperature of denaturement for the L-Citrulline for an interval sufficient to remove at least one contaminant from the L-Citrulline. The processes can also include concentrating the dissolved L-Citrulline relative to the aqueous solution.

Abstract: A stream data processing method is provided, which includes the steps as follows: obtaining from data a program pointer indicating a task to which the pointer belongs, and configures a thread processing engine according to the program pointer; processing simultaneously the data of the different durations of the task or the data of different tasks by a plurality of thread engines; decides whether there is data still not processed, and if yes, returns to the first step; and if no, exits this data processing. A processor for processing a stream data is also provided.

Abstract: Preparation of azetidinone compounds and medical use thereof are provided by the present invention. More particularly, azetidionne compounds, shown as formula (I), wherein R1, R2, R3, R4, R5 and R6 are defined in description, and preparation methods thereof are provided by the present invention. The compounds of the present invention can reduce the levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) in plasma, and can be used as medicaments for reducing cholesterol in blood. Therefore the compounds of the present invention can be used to treat or prevent diseases of atherosclerosis, cacergasia of blood vessel, cardiac failure, coronary artery disease, angiocardiopathy, myocardial, angina, hyperlipoidemia and hypercholesteremia and the like. Preparation method of compounds of formula (I) and intermediate compounds are also provided by the present invention.

Abstract: An apparatus for driving a light emitting diode (LED). A rising edge of a pulse width modulation (PWM) signal is first sensed. Upon sensing the rising edge, a threshold pulse (TP) signal is initiated that has a configured width started when the rising edge is sensed, an LED current with an amplitude at a previously set level is generated, and starting to charge a capacitor which yields a voltage Vcap. Subsequently, a falling edge of either the PWM signal or the TP signal is detected. Upon detecting the failing edge, the circuit stops charging the capacitor, samples, after a first delay from the detected falling edge, the voltage Vcap, and adjusts a level of the amplitude of the LED current based on the sampled voltage Vcap. When the falling edges of both the PWM and TP signal are detected, the LED current is terminated.

Abstract: Processes for producing a suitable purity grade of L-Citrulline are disclosed. The processes can include contacting crude L-Citrulline in an aqueous solution with an adsorptive medium at a temperature above approximately 50° C. and below the temperature of denaturement for the L-Citrulline for an interval sufficient to remove at least one contaminant from the L-Citrulline. The processes can also include concentrating the dissolved L-Citrulline relative to the aqueous solution.

Abstract: An apparatus for driving a light emitting diode (LED). A rising edge of a pulse width modulation (PWM) signal is first sensed. Upon sensing the rising edge, a threshold pulse (TP) signal is initiated that has a configured width started when the rising edge is sensed, an LED current with an amplitude at a previously set level is generated, and starting to charge a capacitor which yields a voltage Vcap. Subsequently, a falling edge of either the PWM signal or the TP signal is detected. Upon detecting the failing edge, the circuit stops charging the capacitor, samples, after a first delay from the detected falling edge, the voltage Vcap, and adjusts a level of the amplitude of the LED current based on the sampled voltage Vcap. When the falling edges of both the PWM and TP signal are detected, the LED current is terminated.

Abstract: The present disclosure relates to bearings, for example, an improved journal bearing. A bushing (44) for use with a journal bearing (40) includes: a cylindricarinterior defining an interior bearing surface (46); a longitudinal axis (45) and an internal diameter (ID); a groove region of the interior bearing surface (46) having a length H along the longitudinal axis; and a set of grooves (48) in the grooved region of the interior bearing surface (46), where N is the number of grooves in the set of grooves (48). Each groove is disposed at a helix angle (?) offset from the longitudinal axis (45) of the bushing (44). The helix angle is approximately equivalent to the following equation: tangent (?)=(?×ID)/(N×H).

Abstract: Excessive residence time in the conduits located between the outlet of a static mixer and a reactor/separator reservoir can lead to undesired by-products, formation of solids, and conduit fouling. This disclosure relates to an improved configuration for a static mixer with reduced transitory time to help reduce the creation of undesired by-products and fouling during the process of mixing, and more particularly to a phosgene reactor comprising a short or very short conduit for reducing the transit time from the static mixer to a reactor/separator reservoir to one second or less.

Abstract: A system and process for removing an inorganic salt from a catalyst roaster belt is disclosed. The system includes an apparatus with a drying vessel having a catalyst roaster belt inlet, a catalyst roaster belt outlet, a heating medium inlet, and a heating medium outlet, wherein the catalyst roaster belt inlet and the catalyst roaster belt outlet are spaced apart along a first direction, the heating medium inlet and the heating medium outlet are spaced apart along a second direction, the heating medium inlet is spaced apart from the catalyst roaster belt inlet in the second direction, and the catalyst roaster belt inlet is between the heating medium inlet and the heating medium outlet along the second direction. The system includes an acid bath and a moveable catalyst roaster belt extending from the acid bath through the catalyst roaster belt inlet and through the catalyst roaster belt outlet.

Abstract: The present invention provides isothermal multitube reactors suitable for the production of chlorinated and/or fluorinated propene and higher alkenes from the reaction of chlorinated and/or fluorinated alkanes and chlorinated and/or fluorinated alkenes. The reactors utilize a feed mixture inlet temperature at least 20° C. different from a desired reaction temperature.

Abstract: The present invention provides adiabatic plug flow reactors suitable for the production of chlorinated and/or fluorinated propene and higher alkenes from the reaction of chlorinated and/or fluorinated alkanes and chlorinated and/or fluorinated alkenes. The reactors comprise one or more designs that minimize the production of by-products at a desired conversion.

Abstract: An apparatus and a method for mixing at least two fluid substances and carrying out or initiating a reaction between them, wherein the apparatus is a static mixer are described. The static mixer includes a fluid receiving chamber, a first conduit passing through the fluid receiving chamber and having at least one tapered aperture therethrough, and a second conduit operatively connected to the fluid receiving chamber.