Patents by Inventor Hua Bai

Hua Bai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150065699
    Abstract: Provided are several types of ginsenoside polymorphic substances and a method for preparing same. In particular, new crystal form A, crystal form B, crystal form C, crystal form E, crystal form F, crystal form I, crystal form K, crystal form L, crystal form M, crystal form N, and crystal form O are involved.
    Type: Application
    Filed: April 1, 2013
    Publication date: March 5, 2015
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Guobin Ren, Changliang Dai, Jinyao Chen, Feng Chen, Minghui Qi, Wenming Zhu, Minghuang Hong, Hua Bai
  • Publication number: 20150057440
    Abstract: Provided are ginsenoside C-K polymorphic forms and a method for preparing same. The ginsenoside C-K polymorphic forms are crystal form D and crystal form H.
    Type: Application
    Filed: April 1, 2013
    Publication date: February 26, 2015
    Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Guobin Ren, Changliang Dai, Jinyao Chen, Feng Chen, Minghui Qi, Wenming Zhu, Minghuang Hong, Hua Bai
  • Patent number: 8946478
    Abstract: Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula (I) are as set out in the description.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: February 3, 2015
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hua Bai, Xuyang Zhao, Yongxiang Gong, Jinqing Zhong, Qifeng Zhu, Xiaoyu Liu, Lifei Liu, Qixian Zhou
  • Patent number: 8940086
    Abstract: Process for making an antibacterial coating includes the following steps. A solution containing titanium dioxide particles and a dispersant is prepared. A mechanical stirring method is employed to prepare a preliminary titanium dioxide dispersed solution. An ultrasonic agitation method is employed to prepare a nanometer titanium dioxide dispersed solution, an average particle size of the titanium dioxide particles being less than or equal to 200 nanometers. Lastly, the nanometer titanium dioxide dispersed solution is mixed with a papermaking coating to prepare an antibacterial coating.
    Type: Grant
    Filed: November 28, 2013
    Date of Patent: January 27, 2015
    Assignee: Ningbo Asia Pulp & Paper Co., Ltd
    Inventors: Shu-Hua Bai, Jun-Ming Wang, Ji-Ping Quan, Meng-Huai Ran, Wei He
  • Publication number: 20150019055
    Abstract: Techniques are presented for synchronous rectification control (SRC) of a DC-DC converter in an electrified vehicle (EV) can include determining a required output current for the DC-DC converter based on a secondary voltage of a secondary battery system of the EV, the DC-DC converter being configured to convert a primary voltage from a primary battery system of the EV to the secondary voltage. The techniques can include determining, at the controller, a switching frequency for the DC-DC converter that causes the DC-DC converter to output the required output current. The techniques can include determining turn-on and turn-off delays of the DC-DC converter based on the required output current and the switching frequency using one or more look-up tables. The techniques can also include controlling the DC-DC converter efficiency based on the turn-on and turn-off delays.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 15, 2015
    Inventors: Zhong Nie, Mengyang Zhang, Dennis Krozek, Fred A. Householder, Hua Bai, Wei Guo, Chen Duan
  • Patent number: 8926918
    Abstract: The present invention provides isothermal multitube reactors suitable for the production of chlorinated and/or fluorinated propene and higher alkenes from the reaction of chlorinated and/or fluorinated alkanes and chlorinated and/or fluorinated alkenes. The reactors utilize a feed mixture inlet temperature at least 20° C. different from a desired reaction temperature.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: January 6, 2015
    Assignee: Dow Global Technologies LLC
    Inventors: Max Markus Tirtowidjojo, Hua Bai, Debashis Chakraborty, Juergen Eiffler, Heinz Groenewald, Kurt Frederick Hirsekorn, Manfred Kokott, William J. Kruper, Jr., Thomas Ulrich Luebbe, Avani Maulik Patel, Shirley Shaw Sexton, Peter Wenzel, Marcus Wobser
  • Publication number: 20140378488
    Abstract: Provided are derivatives substituted by urea associated with 4-substituted-(3-substituted-1H-pyrazole-5-amino)-pyrimidine-2-amino of formula (I), wherein these compounds may selectively regulate or inhibit an information transmission process controlled by natural or variant tyrosine kinase. Also provided are preparation methods and uses of the compounds.
    Type: Application
    Filed: September 5, 2011
    Publication date: December 25, 2014
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Yili Ding, Xuan Yang, Qingyan Yan, Hua Bai, Lifeng Cai, Kenneth Smith, Jian Chai
  • Patent number: 8906947
    Abstract: The invention discloses a method for the separation and purification of epothilones, especially discloses a method for the separation and purification of epothilones B and A using normal phase silica gel chromatography, which comprises loading the sample after dissolving the sample containing epothilones B and A with C1-C7 alkyl halide compounds or mixing the sample with silica gel, then gradient eluting silica gel column by an elution solvent of normal phase silica gel column, and finally obtaining products.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: December 9, 2014
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Jidong Wang, Hui Zhang, Haibin Wang, Lingping Ying, Sheng Wang, Xufang Guan, Hua Bai
  • Publication number: 20140308424
    Abstract: Disclosed is dried fruit or vegetable pulp preparation comprising dried fruit or vegetable pulp and at least one density modifying ingredient. The density modifying ingredient may be selected from the group consisting of complex carbohydrates or humectants.
    Type: Application
    Filed: July 22, 2011
    Publication date: October 16, 2014
    Applicant: NESTEC S.A.
    Inventors: Hua Bai, Yong-Cheng Liao, Zhong-wei Sun, Olivier Ballevre, Qingzhu Zhao
  • Publication number: 20140083635
    Abstract: Process for making an antibacterial coating includes the following steps. A solution containing titanium dioxide particles and a dispersant is prepared. A mechanical stirring method is employed to prepare a preliminary titanium dioxide dispersed solution. An ultrasonic agitation method is employed to prepare a nanometer titanium dioxide dispersed solution, an average particle size of the titanium dioxide particles being less than or equal to 200 nanometers. Lastly, the nanometer titanium dioxide dispersed solution is mixed with a papermaking coating to prepare an antibacterial coating.
    Type: Application
    Filed: November 28, 2013
    Publication date: March 27, 2014
    Applicant: Ningbo Asia Pulp & Paper Co., Ltd.
    Inventors: SHU-HUA BAI, JUN-MING WANG, JI-PING QUAN, MENG-HUAI RAN, WEI HE
  • Publication number: 20140073809
    Abstract: The present invention provides the preparation method for (S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (formula X compound), the preparation methods for its intermediates (S)-1-(3-methoxyphenyl)-N,N-dimethyl-N—((S)-1-phenylethyl)ethanaminium (formula VI compound), (S)-1-(3-hydroxyphenyl)-N,N-dimethyl-N—((S)-1-phenylethyl)ethanaminium (formula VIII compound) and (S)-1-(3-(ethyl(methyl)carbamoyloxy)phenyl)-N,N-dimethyl-N—((S)-1-phenylethyl)ethanaminium (formula IX compound), as well as the method for using above mentioned formula IX compound to prepare rivastigmine which can be used for the treatment of Alzheimer's disease. The preparation method for rivastigmine has a reasonable synthetic design with convenient source of raw materials and high total yield, and the product resulted has high chemical and optical purity, which makes it easy for large-scale. industrial production.
    Type: Application
    Filed: May 16, 2012
    Publication date: March 13, 2014
    Applicants: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Fuli Zhang, Zhezhou Yang, Chunbo Yang, Daoxin Chen, Zhiqing Yang, Rentong Sun, Hua Bai
  • Patent number: 8633000
    Abstract: Processes for producing a suitable purity grade of L-Citrulline are disclosed. The processes can include contacting crude L-Citrulline in an aqueous solution with an adsorptive medium at a temperature above approximately 50° C. and below the temperature of denaturement for the L-Citrulline for an interval sufficient to remove at least one contaminant from the L-Citrulline. The processes can also include concentrating the dissolved L-Citrulline relative to the aqueous solution.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: January 21, 2014
    Assignee: Global Strategic Connections, LLC
    Inventors: Hua Bai, Peijie Yang, Zhengjie Chen, Chongyang Xu, Zhaorui Li, Zigang Zhao, Luyan Jiang, Zongyi Yang, Jiang Li
  • Publication number: 20140011867
    Abstract: The present invention discloses use of borrelidin for preventing and controlling phytophthora root rot of soybean. The present invention also discloses formulations of borrelidin seed coating agents and wettable powders and preparation methods thereof. Borrelidin exhibits significant effects on Phytophthora sojae. As compared with the conventional fungicide metalaxyl which is used for preventing and controlling phytophthora root rot of soybean, the mycelial growth inhibition assay indicates that the IC50 and IC95 values of borrelidin are 1/62 and 1/263, respectively, of those of metalaxyl. In the indoor pot-culture experiment, the seed coating agent and wettable powder exhibit significant controlling effects on phytophthora root rot of soybean.
    Type: Application
    Filed: March 25, 2011
    Publication date: January 9, 2014
    Applicant: ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
    Inventors: Wensheng Xiang, Jidong Wang, Xiangjing Wang, Chongxi Liu, Dianliang Gong, Hua Bai
  • Publication number: 20140010741
    Abstract: The present invention provides isothermal multitube reactors suitable for the production of chlorinated and/or fluorinated propene and higher alkenes from the reaction of chlorinated and/or fluorinated alkanes and chlorinated and/or fluorinated alkenes. The reactors utilize a feed mixture inlet temperature at least 20° C. different from a desired reaction temperature.
    Type: Application
    Filed: September 11, 2013
    Publication date: January 9, 2014
    Applicant: DOW GLOBAL TECHNOLOGIES, LLC
    Inventors: Max Markus Tirtowidjojo, Hua Bai, Debashis Chakraborty, Juergen Eiffler, Heinz Groenewald, Kurt Frederick Hirsekorn, Manfred Kokott, William J. Kruper, Thomas Ulrich Luebbe, Avani Maulik Patel, Shirley Shaw Sexton, Peter Wenzel, Marcus Wobser
  • Patent number: 8623855
    Abstract: Preparation of azetidinone compounds and medical use thereof are provided by the present invention. More particularly, azetidionne compounds, shown as formula (I), wherein R1, R2, R3, R4, R5 and R6 are defined in description, and preparation methods thereof are provided by the present invention. The compounds of the present invention can reduce the levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) in plasma, and can be used as medicaments for reducing cholesterol in blood. Therefore the compounds of the present invention can be used to treat or prevent diseases of atherosclerosis, cacergasia of blood vessel, cardiac failure, coronary artery disease, angiocardiopathy, myocardial, angina, hyperlipoidemia and hypercholesteremia and the like. Preparation method of compounds of formula (I) and intermediate compounds are also provided by the present invention.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: January 7, 2014
    Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
    Inventors: Hua Bai, Xuyang Zhao, Xiaojie Xu, Xiaoyu Liu, Yuncai Zhang, Ying Chen, Xiaohe Zheng, Maojian Gu, Qifeng Zhu, Yong Zhang, Hairong Luo
  • Patent number: 8613899
    Abstract: An apparatus includes a manifold with a chamber for mixing multiple reactants. Gases are jetted into the manifold by a plurality of inlet injectors. The inlet injectors are arranged such that the gases passing into the manifold impinge on each other at a common point to form a mixture. The mixture passes through a plurality of holes in one side of the manifold into a deposition chamber where the mixture of gases impinges on additional gases at a common point to provide a reaction resulting in deposition of solid materials in the deposition chamber. The solid materials are free-standing.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: December 24, 2013
    Assignees: Rohm and Haas Electronic Materials LLC, Dow Global Technologies LLC
    Inventors: Heather A. G. Stern, Vincent DiFilippo, Jitendra S. Goela, Michael A. Pickering, Hua Bai, Debashis Chakraborty, Hangyao Wang
  • Patent number: 8608386
    Abstract: The present disclosure relates to bearings, for example, an improved journal bearing. A bushing (44) for use with a journal bearing (40) includes: a cylindricarinterior defining an interior bearing surface (46); a longitudinal axis (45) and an internal diameter (ID); a groove region of the interior bearing surface (46) having a length H along the longitudinal axis; and a set of grooves (48) in the grooved region of the interior bearing surface (46), where N is the number of grooves in the set of grooves (48). Each groove is disposed at a helix angle (?) offset from the longitudinal axis (45) of the bushing (44). The helix angle is approximately equivalent to the following equation: tangent (?)=(?×ID)/(N×H).
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: December 17, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: Curtis Modtland, Hua Bai
  • Patent number: 8567099
    Abstract: A system and process for removing an inorganic salt from a catalyst roaster belt is disclosed. The system includes an apparatus with a drying vessel having a catalyst roaster belt inlet, a catalyst roaster belt outlet, a heating medium inlet, and a heating medium outlet, wherein the catalyst roaster belt inlet and the catalyst roaster belt outlet are spaced apart along a first direction, the heating medium inlet and the heating medium outlet are spaced apart along a second direction, the heating medium inlet is spaced apart from the catalyst roaster belt inlet in the second direction, and the catalyst roaster belt inlet is between the heating medium inlet and the heating medium outlet along the second direction. The system includes an acid bath and a moveable catalyst roaster belt extending from the acid bath through the catalyst roaster belt inlet and through the catalyst roaster belt outlet.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: October 29, 2013
    Assignee: Dow Technology Investments LLC
    Inventors: Hua Bai, Ralph S. Kruska
  • Publication number: 20130270356
    Abstract: An apparatus includes a manifold with a chamber for mixing multiple reactants. Gases are jetted into the manifold by a plurality of inlet injectors. The inlet injectors are arranged such that the gases passing into the manifold impinge on each other at a common point to form a mixture. The mixture passes through a plurality of holes in one side of the manifold into a deposition chamber where the mixture of gases impinges on additional gases at a common point to provide a reaction resulting in deposition of solid materials in the deposition chamber. The solid materials are free-standing.
    Type: Application
    Filed: April 17, 2012
    Publication date: October 17, 2013
    Applicants: Dow Globel Technologies LLC, Rohm and Haas Electronic Materials LLC
    Inventors: Heather A. G. Stern, Vincent DiFilippo, Jitendra S. Goela, Michael A. Pickering, Hua Bai, Debashis Chakraborty, Hangyao Wang
  • Patent number: 8558041
    Abstract: The present invention provides isothermal multitube reactors suitable for the production of chlorinated and/or fluorinated propene and higher alkenes from the reaction of chlorinated and/or fluorinated alkanes and chlorinated and/or fluorinated alkenes. The reactors utilize a feed mixture inlet temperature at least 20° C. different from a desired reaction temperature.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: October 15, 2013
    Assignee: Dow Global Technologies, LLC
    Inventors: Max M. Tirtowidjojo, Hua Bai, Debashis Chakraborty, Juergen Eiffler, Heinz Groenewald, Kurt F. Hirsekorn, Manfred Kokott, William J. Kruper, Jr., Thomas U. Luebbe, Avani M. Patel, Shirley S. Sexton, Peter Wenzel, Marcus Wobser