Patents by Inventor Huan Qi

Huan Qi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12216040
    Abstract: Provided are a sample analyzer and a sample analysis method. The sample analyzer includes: a sampling apparatus configured to collect a blood sample; a sample preparation apparatus configured to mix the blood sample with a hemolytic agent and a dye to prepare a test sample liquid; an optical detection apparatus configured to detect side-scattered light signals and fluorescence signals generated by particles in the test sample liquid; and a processor configured to: generate a scatter diagram based on at least the side-scattered light signals and the fluorescence signals, and obtain a predetermined feature region, wherein an intensity of side-scattered light corresponding to a central position of the predetermined feature region is greater than an intensity of side-scattered light corresponding to a central position of a region containing neutrophil granulocyte population; and obtain a blast cell parameter based on the predetermined feature region.
    Type: Grant
    Filed: April 7, 2022
    Date of Patent: February 4, 2025
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Wenbo Zheng, Bo Ye, Mingjin Guo, Chuanjian Wu, Huan Qi
  • Publication number: 20240426763
    Abstract: Embodiments of the present invention relate to a sample image photographing method and a corresponding sample image photographing apparatus.
    Type: Application
    Filed: September 9, 2024
    Publication date: December 26, 2024
    Inventors: Huan QI, Wei LUO, Yuan XING, Bo YE, Yi YE, Shan YU
  • Patent number: 12158409
    Abstract: Disclosed are a blood analysis system, a blood analyzer, a blood analysis method and a storage medium. The blood analysis method includes: acquiring at least two types of optical signals of a test sample derived from a blood sample, wherein red blood cells in the test sample are lysed, blood cells in the test sample are stained by a fluorescence dye, and the at least two types of optical signals include scattered light signals and/or fluorescent signals; generating a scattergram based on the at least two types of optical signals; identifying a preset region in the scattergram based on the at least two types of optical signals; and acquiring detection data of a platelet subpopulation based on the preset region.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: December 3, 2024
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Huan Qi, Wenbo Zheng, Yi Ye
  • Patent number: 12142065
    Abstract: A device for analyzing cell morphology and a method for identifying cells are provided. A digital camera photographs a cell image of a blood sample under a low-magnification objective lens. A processor identifies and positions suspected cells of preset type in the cell image to obtain an identification result. Based on the identification result and a target number, the processor determines a number of suspected cells of preset type to be identified and positioned under the low-magnification objective lens. The digital camera further photographs, under a high-magnification objective lens, the suspected cells of preset type identified and positioned, and then the processor identifies whether the suspected cells of preset type photographed are cells of preset type, to count the number of cells of preset type photographed under the high-magnification objective lens and obtain a statistical value. If the statistical value?the target number, photographing is stopped.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: November 12, 2024
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Qiyao Wang, Yuan Xing, Huan Qi, Shan Yu, Qiaoni Chen
  • Patent number: 12135287
    Abstract: A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
    Type: Grant
    Filed: October 9, 2023
    Date of Patent: November 5, 2024
    Inventors: Huan Qi, Wenbo Zheng, Bo Ye, Zhaoyang Li, Yi Ye
  • Publication number: 20240361231
    Abstract: The present invention relates to a blood cell analyzer, which includes a sample aspiration device used for aspirating a blood sample of a subject to be tested, a sample preparation device used for preparing a test sample, an optical detection device used for testing the test sample to obtain optical information, and a processor. The processor obtains from first optical information of a first test sample a first leukocyte parameter of a first target particle population in the first test sample; obtains from second optical information of a second test sample a second leukocyte parameter of a second target particle population in the second test sample, the first or second leukocyte parameters including a cell characteristic parameter; and on the basis of the first leukocyte parameter and the second leukocyte parameter, obtains an infection marker parameter for evaluating an infection state of the subject, and outputs the infection marker parameter.
    Type: Application
    Filed: June 29, 2024
    Publication date: October 31, 2024
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan QI, Xiaomei ZHANG, Shiyao PAN, Jin LI, Chuanjian WU, Yi YE
  • Publication number: 20240353311
    Abstract: A blood cell analyzer, a method, and a use of an infection marker parameter. The blood cell analyzer includes: a sample aspiration device for aspirating a blood sample of a subject to be tested, a sample preparation device for preparing a test sample, an optical detection device for detecting the test sample to obtain optical information, and a processor. The processor obtains at least one leukocyte parameter of at least one leukocyte particle population in the test sample from the optical information, obtains an infection marker parameter on the basis of the at least one leukocyte parameter, and outputs the infection marker parameter, the infection marker parameter being used for predicting whether the subject is likely to progress to sepsis within a certain time period starting from when the blood sample to be tested is collected. Therefore, risk of sepsis can be quickly and accurately predicted in advance.
    Type: Application
    Filed: June 29, 2024
    Publication date: October 24, 2024
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Jin LI, Xiaomei ZHANG, Shiyao PAN, Yushuai MA, Huan QI, Yi YE
  • Patent number: 12085513
    Abstract: Embodiments of the present invention relate to a sample image photographing method and a corresponding sample image photographing apparatus.
    Type: Grant
    Filed: February 28, 2023
    Date of Patent: September 10, 2024
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan Qi, Wei Luo, Yuan Xing, Bo Ye, Yi Ye, Shan Yu
  • Patent number: 12046333
    Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: July 23, 2024
    Assignee: SHENZHEN MINDRAY BIO- MEDICAL ELECTRONICS CO., LTD.
    Inventors: Bo Ye, Changsong Hu, Huan Qi, Wenbo Zheng
  • Publication number: 20240230621
    Abstract: Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system and a storage medium.
    Type: Application
    Filed: December 11, 2023
    Publication date: July 11, 2024
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan QI, Bo YE, Wenbo ZHENG, Changsong HU, Qi YU
  • Publication number: 20240133864
    Abstract: Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system and a storage medium.
    Type: Application
    Filed: December 11, 2023
    Publication date: April 25, 2024
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan QI, Bo YE, Wenbo ZHENG, Changsong HU, Qi YU
  • Publication number: 20240044793
    Abstract: A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
    Type: Application
    Filed: October 9, 2023
    Publication date: February 8, 2024
    Inventors: Huan QI, Wenbo ZHENG, Bo YE, Zhaoyang LI, Yi YE
  • Patent number: 11874212
    Abstract: A blood analysis method, a blood analysis system, and a storage medium are provided. The blood analysis method includes: providing a blood sample; mixing a first aliquot of the blood sample with a diluent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample to obtain first volume distribution data; detecting at least two types of optical signals of the second test sample to obtain second volume distribution data; acquiring red blood cell test data of the blood sample; determining, based on the first volume distribution data, the second volume distribution data, and the red blood cell test data, whether the blood sample contains schistocytes; and if the determination result is yes, providing a warning that the blood sample may contain schistocytes.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: January 16, 2024
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Wenbo Zheng, Huan Qi, Zhaoyang Li
  • Patent number: 11841358
    Abstract: Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system (100) and a storage medium.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: December 12, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Huan Qi, Bo Ye, Wenbo Zheng, Changsong Hu, Qi Yu
  • Publication number: 20230333093
    Abstract: A sample analyzer includes a sample preparation device, an impedance testing device, an optical testing device, and a controller. The controller is configured to control the impedance testing device to test a first test sample to obtain a first platelet counting result for a test blood sample based on electronic information of the first test sample; control the optical testing device to test a second test sample to obtain a second platelet counting result for the test blood sample based only on optical information of the second test sample or based on both the electronic information of the first test sample and the optical information of the second test sample; determine whether the first platelet counting result is unreliable due to abnormality of the test blood sample; and output the first and/or the second platelet counting result according to the result of the determination.
    Type: Application
    Filed: April 14, 2023
    Publication date: October 19, 2023
    Inventors: Wenbo ZHENG, Bo YE, Donglan YAO, Huan QI, Yi YE
  • Patent number: 11781983
    Abstract: A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: October 10, 2023
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan Qi, Wenbo Zheng, Bo Ye, Zhaoyang Li, Yi Ye
  • Publication number: 20230314296
    Abstract: A sample analysis system and method, a sample image analysis system, and a hematology analyzer, the sample analysis system including at least one hematology analyzer, a controller, a first transport device, a sample slide preparation device and a sample image capturing device, wherein one of the hematology analyzers is configured to analyze a first test blood sample of a subject so as to obtain a sample analysis result; the controller is configured to control the first transport device to transport the first blood sample to the sample slide preparation device when the sample analysis result meets a preset condition; the sample slide preparation device is configured to prepare a sample slide of the first blood sample; the sample image capturing device is configured to image a sample region in the sample slide so as to obtain a sample image; and the controller is further configured to generate a retest instruction when the sample image includes information indicating that the first blood sample is an abnormal s
    Type: Application
    Filed: June 5, 2023
    Publication date: October 5, 2023
    Inventors: Yi YE, Bo YE, Yuan XING, Huan QI, Shan YU
  • Publication number: 20230251205
    Abstract: Embodiments of the present invention relate to a sample image photographing method and a corresponding sample image photographing apparatus.
    Type: Application
    Filed: February 28, 2023
    Publication date: August 10, 2023
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Huan QI, Wei LUO, Yuan XING, Bo YE, Yi YE, Shan YU
  • Patent number: 11709123
    Abstract: A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: July 25, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Guanzhen Wang, Bo Ye, Huan Qi
  • Publication number: 20230071301
    Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
    Type: Application
    Filed: November 14, 2022
    Publication date: March 9, 2023
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Bo YE, Changsong HU, Huan QI, Wenbo ZHENG