Patents by Inventor Huan Qi

Huan Qi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11709123
    Abstract: A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: July 25, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Guanzhen Wang, Bo Ye, Huan Qi
  • Publication number: 20230071301
    Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
    Type: Application
    Filed: November 14, 2022
    Publication date: March 9, 2023
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Bo YE, Changsong HU, Huan QI, Wenbo ZHENG
  • Patent number: 11585040
    Abstract: The present application relates to washing machine assembly. The described washing machine assembly comprises a body, an outer drum, an inner drum, a door assembly and an ultrasound apparatus; the outer drum is connected to the body, and an accommodating container and an open groove that communicate with each other are formed inside of the outer drum; the inner drum is located inside of the accommodating container and a washing tank is formed in the inner drum; the door assembly is rotatingly connected on the outer drum, the door assembly covers the outer drum so as to block the open groove, and an mounting hole is formed inside of the door assembly; the ultrasound apparatus is located inside of the mounting hole and is connected to the door assembly, and the ultrasound apparatus is at least partially located inside of the washing tank.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: February 21, 2023
    Assignee: TCL Home Appliances (Hefei) Co., Ltd.
    Inventors: Wengen Xu, Benyang Bian, Wenjie Zhang, Huan Qi
  • Patent number: 11501852
    Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: November 15, 2022
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Bo Ye, Changsong Hu, Huan Qi, Wenbo Zheng
  • Publication number: 20220334046
    Abstract: Provided are a sample analyzer and a sample analysis method. The sample analyzer includes: a sampling apparatus configured to collect a blood sample; a sample preparation apparatus configured to mix the blood sample with a hemolytic agent and a dye to prepare a test sample liquid; an optical detection apparatus configured to detect side-scattered light signals and fluorescence signals generated by particles in the test sample liquid; and a processor configured to: generate a scatter diagram based on at least the side-scattered light signals and the fluorescence signals, and obtain a predetermined feature region, wherein an intensity of side-scattered light corresponding to a central position of the predetermined feature region is greater than an intensity of side-scattered light corresponding to a central position of a region containing neutrophil granulocyte population; and obtain a blast cell parameter based on the predetermined feature region.
    Type: Application
    Filed: April 7, 2022
    Publication date: October 20, 2022
    Inventors: Wenbo ZHENG, Bo YE, Mingjin GUO, Chuanjian WU, Huan QI
  • Publication number: 20220334100
    Abstract: A sample analysis system, method and a cell image analysis device. The sample analysis system includes a blood cell analyzer, a smear preparation apparatus, a cell image analysis apparatus, and a controller. The controller obtains a test result of at least one sample from the blood cell analyzer. When one sample needs to be analyzed by the cell image analysis device, the controller can further control an imaging condition used by the cell image analysis device according to a value of at least one type of cells in the test result of the sample, such that the cell image analysis device can automatically selects an imaging condition matching the test result for imaging according to different test results of the sample. Therefore, a matching imaging condition is used to specifically capture and analyze cell images of a smear of the sample, thereby improving processing efficiency and accuracy.
    Type: Application
    Filed: June 29, 2022
    Publication date: October 20, 2022
    Inventors: Huan QI, Chaoyang LI, Yi YE, Bo YE, Shan YU, Jin LI, Xuerong LI
  • Publication number: 20220334099
    Abstract: Blood analysis apparatus, method, and storage medium are provided, including: obtaining optical signals of a first test sample; determining a first test result of a blood sample from the optical signals of the first test sample; determining whether any one or a combination of reticulocytes, immature platelets and large-volume platelets in the blood sample is abnormal from the optical signals of the first test sample; outputting the first test result if it is determined that reticulocytes, immature platelets and large-volume platelets in the blood sample are normal; if it is determined that any one or a combination of reticulocytes, immature platelets and large-volume platelets in the blood sample is abnormal, preparing a second test sample and obtaining optical signals of the second test sample; and obtaining a second test result of the blood sample from the optical signals of the second test sample and outputting the first test result.
    Type: Application
    Filed: April 13, 2022
    Publication date: October 20, 2022
    Inventors: Wenbo ZHENG, Bo YE, Donglan YAO, Yi YE, Huan QI
  • Publication number: 20220326140
    Abstract: Provided are cell image analysis devices and sample analysis methods. A sample smear of a test sample is imaged by an imaging device in an assigned analysis mode to obtain first cell images of the test sample, which are identified and analyzed by a control device. If it is identified that there is preset abnormality in the sample smear, an analysis mode different from the assigned analysis mode and corresponding to the present abnormality is determined as an additional analysis mode, and the imaging device is controlled to image the sample smear in the additional analysis mode. The additional analysis mode matches with the preset abnormality, so that the imaging device is allowed to obtain cell images in the additional analysis mode, to identify and analyze the cell images matching the preset abnormality, thereby increasing processing efficiency and accuracy of processing result.
    Type: Application
    Filed: June 22, 2022
    Publication date: October 13, 2022
    Inventors: Bo YE, Bin JIANG, Wei LUO, Yuan XING, Huan QI, Qiaoni CHEN, Shan YU, Yi YE
  • Publication number: 20220327848
    Abstract: A device for analyzing cell morphology and a method for identifying cells are provided. A digital camera photographs a cell image of a blood sample under a low-magnification objective lens. A processor identifies and positions suspected cells of preset type in the cell image to obtain an identification result. Based on the identification result and a target number, the processor determines a number of suspected cells of preset type to be identified and positioned under the low-magnification objective lens. The digital camera further photographs, under a high-magnification objective lens, the suspected cells of preset type identified and positioned, and then the processor identifies whether the suspected cells of preset type photographed are cells of preset type, to count the number of cells of preset type photographed under the high-magnification objective lens and obtain a statistical value. If the statistical value?the target number, photographing is stopped.
    Type: Application
    Filed: May 31, 2022
    Publication date: October 13, 2022
    Inventors: Bo YE, Qiyao WANG, Yuan XING, Huan QI, Shan YU, Qiaoni CHEN
  • Patent number: 11402370
    Abstract: An alarming method for a platelet aggregation sample can include providing a blood sample, preparing a first test sample from the blood sample under a first reaction condition, acquiring a test signal of the first test sample, and obtaining first platelet test data. The method can also include preparing a second test sample from the blood sample under a second reaction condition, acquiring a test signal of the second test sample, and obtaining second platelet test data. The method can further include obtaining an evaluation result based on the first platelet test data and the second platelet test data, determining whether the evaluation result meets a predetermined condition, and alarming that the blood sample may be the platelet aggregation sample if the evaluation result meets the predetermined condition. The second reaction condition may include a reaction condition for reducing the platelet aggregation degree of the blood sample.
    Type: Grant
    Filed: March 4, 2020
    Date of Patent: August 2, 2022
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Bo Ye, Wenbo Zheng, Huan Qi, Xuerong Li
  • Publication number: 20210318223
    Abstract: A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
    Type: Application
    Filed: June 21, 2021
    Publication date: October 14, 2021
    Inventors: Guanzhen WANG, Bo YE, Huan QI
  • Publication number: 20210310178
    Abstract: The present application relates to washing machine assembly. The described washing machine assembly comprises a body, an outer drum, an inner drum, a door assembly and an ultrasound apparatus; the outer drum is connected to the body, and an accommodating container and an open groove that communicate with each other are formed inside of the outer drum; the inner drum is located inside of the accommodating container and a washing tank is formed in the inner drum; the door assembly is rotatingly connected on the outer drum, the door assembly covers the outer drum so as to block the open groove, and an mounting hole is formed inside of the door assembly; the ultrasound apparatus is located inside of the mounting hole and is connected to the door assembly, and the ultrasound apparatus is at least partially located inside of the washing tank.
    Type: Application
    Filed: November 5, 2019
    Publication date: October 7, 2021
    Inventors: Wengen XU, Benyang BIAN, Wenjie ZHANG, Huan QI
  • Patent number: 11125687
    Abstract: A method for identifying fragmented red blood cells comprising: acquiring side scatter light signals and fluorescence signals of cell particles in a sample liquid; and distinguishing and identifying a fragmented red blood cell population from the cell particles according to the side scatter light signals and the fluorescence signals of the cell particles. The fragmented red blood cell population can be identified from the cell particles by processing and analyzing the side scatter light signals and fluorescence signals of the sample liquid. The present application further provides a device for identifying fragmented red blood cells, a blood cell analyzer and an analysis method. Fragmented red blood cells can be identified according to the fluorescence that characterizes a nucleic acid content in a cell particle and the side scatter light, thus reducing errors in identification and counting.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: September 21, 2021
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Wenbo Zheng, Bo Ye, Huan Qi, Shan Yu, Xiujuan Li, Zhaoyang Li
  • Patent number: 11105742
    Abstract: Disclosed are nucleated red blood cell warning devices and methods, and flow cytometers using the same. The devices, methods and flow cytometers can warn whether nucleated red blood cells exist in a blood sample. The warning device may obtain forward-scattered light information, side-scattered light information and fluorescence information when cells in the blood sample pass through a detection region of the flow cytometer. The warning device may generate a side-scattered light-fluorescence dot plot, so as to classify leucocytes into four groups, and may generate a forward-scattered light-fluorescence dot plot, where the forward-scattered light-fluorescence dot plot can include a leucocyte group region. The warning device may obtain a predetermined feature region located at the left side of the leucocyte group region, perform statistics on the amount of characterization cells in the predetermined feature region, and provide a warning when the number of the characterization cells exceeds a threshold value.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: August 31, 2021
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Huan Qi, Cheng Qian
  • Publication number: 20210164885
    Abstract: Disclosed are a method for detecting a blood sample, a blood cell analyzer, and a storage medium. The method includes: acquiring at least two types of optical signal values of cells in a sample from a target detection channel, and generating a scattergram or a data array according to the at least two types of optical signal values of the cells; detecting cell distribution information of an aging characteristic region in the scattergram or data array; and outputting a detection result according to the cell distribution information.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 3, 2021
    Inventors: Bo YE, Wenbo ZHENG, Jin LI, Huan QI, Ruiteng TANG
  • Patent number: 10983042
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: April 20, 2021
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd
    Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
  • Publication number: 20210041344
    Abstract: Disclosed are a blood analysis system, a blood analyzer, a blood analysis method and a storage medium. The blood analysis method includes: acquiring at least two types of optical signals of a test sample derived from a blood sample, wherein red blood cells in the test sample are lysed, blood cells in the test sample are stained by a fluorescence dye, and the at least two types of optical signals include scattered light signals and/or fluorescent signals; generating a scattergram based on the at least two types of optical signals; identifying a preset region in the scattergram based on the at least two types of optical signals; and acquiring detection data of a platelet subpopulation based on the preset region.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 11, 2021
    Inventors: Bo YE, Huan QI, Wenbo ZHENG, Yi YE
  • Publication number: 20210041361
    Abstract: A method, system and storage medium for providing an alarm for indicating that an abnormality is present in a sample analyzer are provided. The method includes: mixing a first aliquot of a blood sample with a diluent agent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample; detecting at least two types of optical signals of the second test sample; acquiring first platelet detection data based on the electrical impedance signals; acquiring second platelet detection data based on the at least two types of optical signals; acquiring an evaluation result based on a difference between the first platelet detection data and the second platelet detection data; determining whether the evaluation result meets a preset condition to provide an alarm.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 11, 2021
    Inventors: Huan QI, Wenbo ZHENG, Bo YE, Zhaoyang LI, Yi YE
  • Publication number: 20210041343
    Abstract: A blood analysis method, a blood analysis system, and a storage medium are provided. The blood analysis method includes: providing a blood sample; mixing a first aliquot of the blood sample with a diluent to prepare a first test sample; mixing a second aliquot of the blood sample with a lytic reagent to prepare a second test sample; detecting electrical impedance signals of the first test sample to obtain first volume distribution data; detecting at least two types of optical signals of the second test sample to obtain second volume distribution data; acquiring red blood cell test data of the blood sample; determining, based on the first volume distribution data, the second volume distribution data, and the red blood cell test data, whether the blood sample contains schistocytes; and if the determination result is yes, providing a warning that the blood sample may contain schistocytes.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 11, 2021
    Inventors: Bo YE, Wenbo ZHENG, Huan QI, Zhaoyang LI
  • Publication number: 20210033592
    Abstract: A blood analyzer and a blood analysis method thereof are provided. The blood analyzer includes a test sample preparation apparatus, a flow chamber, a measurement apparatus and a data processor. The method adopts a white blood cell measurement channel to detect a test blood sample subjected to hemolysis and fluorescence staining and utilizes data in a blood ghost region to identify reticulocyte particles, thereby realizing differentiation of reticulocytes and large platelets and realizing finer classification and count of reticulocytes without separately designing an optical detection channel in the blood analyzer. A computer readable storage medium is also disclosed, in which a program is stored, and the program can be executed by the data processor to implement the above method.
    Type: Application
    Filed: October 20, 2020
    Publication date: February 4, 2021
    Inventors: Bo YE, Huan QI, Wenbo ZHENG, Yi YE