Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: A detection device includes a frame, a transport mechanism, detection mechanisms, and a grasping mechanism. The transport mechanism includes a feeding line, a first flow line, and a second flow line arranged in parallel on the frame. The detection mechanisms are arranged on the frame and located on two sides of the transport mechanism. The grasping mechanism is arranged on the frame and used to transport workpieces on the feeding line to the detection mechanisms, transport qualified workpieces to the first flow line, and transport unqualified workpieces to the second flow line.

Abstract: A method of making photolithography mask plate is provided. The method includes: providing a carbon nanotube composite structure, wherein the carbon nanotube composite structure comprises a carbon nanotube layer and a chrome layer coated on the carbon nanotube layer; locating the carbon nanotube composite structure on a substrate to expose partial surfaces of the substrate; and depositing a cover layer on the carbon nanotube composite structure.

Abstract: A method of making photolithography mask plate is provided. The method includes: providing a carbon nanotube layer on a substrate; depositing a chrome layer on the carbon nanotube layer, wherein the chrome layer includes a first patterned chrome layer and a second patterned chrome layer, the first patterned chrome layer is located on the carbon nanotube layer, and the second patterned chrome layer is deposited on the substrate corresponding to holes of the carbon nanotube layer; transferring the carbon nanotube layer with the first patterned chrome layer thereon from the substrate to a base, and the carbon nanotube layer being in contact with the base; and depositing a cover layer on the first patterned chrome layer.

Abstract: A method for making a field effect transistor includes providing a graphene nanoribbon composite structure. The graphene nanoribbon composite structure includes a substrate and a plurality of graphene nanoribbons spaced apart from each other. The substrate includes a plurality of protrusions spaced apart from each other, and one of the plurality of graphene nanoribbons is on the substrate and between two adjacent protrusions. An interdigital electrode is placed on the graphene nanoribbon composite structure, and the interdigital electrode covers the plurality of protrusions and is electrically connected to the plurality of graphene nanoribbons.

Abstract: The present disclosure is directed to a semiconductor device. The semiconductor device includes a substrate, an insulating layer disposed on the substrate, a first conductive feature disposed in the insulating layer, and a capacitor structure disposed on the insulating layer. The capacitor structure includes a first electrode, a first dielectric layer, a second electrode, a second dielectric layer, and a third electrode sequentially stacked. The semiconductor device also includes a first via connected to the first electrode and the third electrode, a second via connected to the second electrode, and a third via connected to the first conductive feature. A part of the first via is disposed in the insulating layer. A portion of the first conductive feature is directly under the capacitor structure.

Abstract: A method includes forming isolation regions extending into a semiconductor substrate. A semiconductor strip is between the isolation regions. The method further includes recessing the isolation regions so that a top portion of the semiconductor strip protrudes higher than top surfaces of the isolation regions to form a semiconductor fin, measuring a fin width of the semiconductor fin, generating an etch recipe based on the fin width, and performing a thinning process on the semiconductor fin using the etching recipe.

Abstract: A full-automatic detection apparatus and system for important zoonotic pathogen, and a control method therefor. The full-automatic detection apparatus for important zoonotic pathogen includes: a base capable of moving; an air collection device, configured to collect a to-be-detected sample in air along with the movement of the base; a nucleic acid detection and analysis device, configured to detect the to-be-detected sample collected by the air collection device to determine whether an infectious pathogen exists in the to-be-detected sample; an intelligent mobile device, configured to plan and control a moving path of the base; and a control device, configured to control the intelligent mobile device to plan and control the moving path of the base and to control a sampling period of the air collection device according to a control instruction of the terminal, and transmit a detection result from the nucleic acid detection and analysis device to the terminal.

Abstract: Provided is a high-stability T cell receptor (TCR). The TCR comprises (i) the whole or a part of TCR? chain except a transmembrane domain thereof, and (ii) the whole or a part of TCR? chain except a transmembrane domain thereof, both the (i) and the (ii) comprising a functional variable domain and at least a part of a constant domain of a TCR chain. An artificial interchain disulfide bond links the constant domains of the TCR? and ? chains, and a Tm value of the T cell receptor is greater than or equal to 45° C.

Abstract: This application relates to a chip-to-module cable assembly, includes a first joint, a second joint and a first flexible PCB cable, the flexible PCB cable, including flexible material parts located on upper and lower layers and a connection portion located on a middle layer, wherein the connection portion comprises two rigid material portions respectively located at end portions of the flexible material parts on the upper and lower layers and a hollow portion between the two rigid material portions, the flexible material parts each comprises at least one conducting wire, one end of each of the at least one conducting wire is connected to a first interface terminal of the first joint, and another end of the conducting wire is connected to a second interface terminal of a second joint.

Abstract: Aspects of the invention include a computer-implemented method by executing, via a processor, a bottleneck model training process for microservices in a microservice system, wherein for each of the microservices the bottleneck model training process filters out a subset of training data based at least in part on a current situation setting. Building, via the processor, a bottleneck indicator model for each of the microservices using information from the bottleneck model training process, convergence points for an expected response time. Executing, via the processor, a bottleneck identification process for providing system alerts when a bottleneck is identified, wherein the bottleneck identification process uses analysis to monitor a data stream according to the bottleneck indicator model which uses the convergence points for response times.

Abstract: The fully-automatic closed-loop detection method includes: comparing a SCD file of a to-be-tested substation with a device-type data template file, so as to determine whether configuration information about the to-be-tested substation is correct; when the configuration information about the to-be-tested substation is correct, parsing the SCD file of the to-be-tested substation and generating a SSD topological diagram of the to-be-tested substation; and acquiring a testing item from a predetermined testing item library in accordance with the SSD topological diagram of the to-be-tested substation, generating a testing scheme for the to-be-tested substation, performing a testing operation and outputting a testing result.

Abstract: An adjusting method for a terminal includes obtaining at least one channel parameter of a wireless fidelity (WIFI) channel within a first preset time period; and shortening a scan time period of the WIFI channel from a preset scan time period to a value smaller than a second preset time period in response to the at least one channel parameter of the WIFI channel representing that a channel environment type of the WIFI channel is simple. A terminal and a non-transitory computer-storage are also provided.

Abstract: A detection device includes a frame, a transport mechanism, detection mechanisms, and a grasping mechanism. The transport mechanism includes a feeding line, a first flow line, and a second flow line arranged in parallel on the frame. The detection mechanisms are arranged on the frame and located on two sides of the transport mechanism. The grasping mechanism is arranged on the frame and used to transport workpieces on the feeding line to the detection mechanisms, transport qualified workpieces to the first flow line, and transport unqualified workpieces to the second flow line.

Abstract: A method for evaluating the mechanical state of a high-voltage shunt reactor based on vibration characteristics is disclosed, relating to the technical field of electrical equipment fault diagnosis. The method includes: based on historical state data and real-time vibration and noise signal data of the high-voltage shunt reactor and through an LSTM neural network time series prediction method, comparing deviation between predicted characteristic value and actual characteristic value, and determining whether the high-voltage shunt reactor has mechanical defects or failures. By using the historical state data and the real-time vibration and noise signal data of the high-voltage shunt reactor, an LSTM neural network time series prediction method, as well as comparison of the deviation between the predicted characteristic value and the actual characteristic value, etc., the evaluation of the mechanical state of the high-voltage shunt reactor is realized.

Abstract: Aspects of the invention include a computer-implemented method by executing, via a processor, a bottleneck model training process for microservices in a microservice system, wherein for each of the microservices the bottleneck model training process filters out a subset of training data based at least in part on a current situation setting. Building, via the processor, a bottleneck indicator model for each of the microservices using information from the bottleneck model training process, convergence points for an expected response time. Executing, via the processor, a bottleneck identification process for providing system alerts when a bottleneck is identified, wherein the bottleneck identification process uses analysis to monitor a data stream according to the bottleneck indicator model which uses the convergence points for response times.

Abstract: The present invention discloses a method for preparing a halogen-free low-smoke intrinsic flame-retardant nylon 66 composite material, which is implemented according to a conventional preparation process by taking an organic acid-modified metal hydroxide as a flame retardant. According to the present invention, an organic acid containing flame-retardant elements such as P, N and S is used for carrying out reactive modification on the metal hydroxide, so that the agglomeration behavior of the metal hydroxide in a polymer is effectively reduced, the compatibility between the flame retardant and nylon 66 is improved. Meanwhile, a series of flame-retardant functional groups such as P, N and S are introduced, so that the flame retardancy of the nylon 66 is greatly improved, the smoke suppression effect is achieved to a certain extent. Therefore, the prepared intrinsic nylon 66 composite material has desirable flame retardancy (an oxygen index can reach 25.8) and low smoke effect.

Abstract: A system for in-situ testing of mechanical properties of materials in static and dynamic load spectra, that includes: an Arcan biaxial clamping subsystem, a press-in test subsystem, a biaxial fatigue test subsystem, a biaxial pre-tension loading subsystem, a signal detection subsystem, and a support and adjustment subsystem. A combined guide mechanism in the Arcan biaxial clamping subsystem is rigidly connected to a guide mechanism support block, an x-direction three sensor base and a y-direction force sensor base in the support and adjustment subsystem by threaded connections, respectively. A laser transmitter, a voice coil motor and a laser receiver in the press-in test subsystem are rigidly connected to a two-degree-of-freedom electric moving platform for the laser transmitter, a two-degree-of-freedom electric moving platform for the voice coil motor and a two-degree-of-freedom electric moving platform for the laser receiver in the support and adjustment subsystem by threaded connections, respectively.

Abstract: The invention discloses a reservoir tail reverse regulation method for native fish protection, comprising the steps that firstly, a breeding habitat of native fishes at reservoir tail of a cascade hydroelectric dam is determined; secondly, breeding characteristics of migration native fishes are determined, and an ecological conservation project of a reach of the breeding habitat at reservoir tail is carried out; thirdly, the length of the reservoir tail of a downstream hydropower station of a cascade hydroelectric project in March to May is determined through a field investigation, and the maximum range of a natural river channel downstream of the upstream cascade power station is judged and finally, the flow state of the reach at reservoir tail is reversely regulated to achieve the goal of discharging water of the natural river channel at the reservoir tail and ensuring the natural flow state of the natural river channel.

Abstract: Automatically reserving a requested resource in real-time is provided. In response to posting a resource request message that includes a set of resource request criteria on a network, a set of resource availability options is received from a set of resource service providers via the network using a negotiation communication channel. The set of resource availability options received from the set of resource service providers is ranked based on an amount of matching between constraints of each respective resource availability option and the set of resource request criteria. The set of resource availability options is displayed by rank from a greatest amount to a least amount of matching in a resource negotiation table.