Patents by Inventor Hyeon Jin Kim
Hyeon Jin Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220409678Abstract: Microorganisms for lowering blood ammonia level and composition for protecting neuronal cells containing the same, particularly relates to microbes or a symbiotic pair that has a neuroprotective function by lowering blood ammonia levels or reducing ammonia levels in the body and composition for protecting neuronal cells comprising the microbes. The microorganisms having a neuroprotective function by lowering the blood ammonia level can be selected from the group that include, but not limited to, a Lactobacillus sp. strain and a Streptococcus sp. strain. The ammonia removal strains and the composition have a neuroprotective effect by their excellent ability to remove neurotoxic ammonia, and thus can be widely used as a preventive or therapeutic agent for hyperammonemia and neurological diseases caused thereby.Type: ApplicationFiled: November 19, 2020Publication date: December 29, 2022Inventors: Hyeon Jin KIM, Sang Woo KIM, Seong Tshool HONG
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Patent number: 11531866Abstract: A clustering method includes configuring a network with clustering target objects; collecting significance of the clustering target objects; performing network embedding for outputting a set of vectors representing neighboring objects of the clustering target objects constituting the network using a neural network; and performing clustering on the clustering target objects using the set of vectors and information on each of the clustering target objects, wherein the neural network is trained so that neighboring objects having high significance are output with higher probability.Type: GrantFiled: October 22, 2019Date of Patent: December 20, 2022Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Yeo Chan Yoon, Hyeon Jin Kim, Soo Myung Park, Hyung Keun Jee
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Patent number: 11512126Abstract: A non-naturally occurring chimeric polypeptide having an activity provided by a TGF-beta family member is disclosed. The chimeric polypeptide of an embodiment comprises two or more domains or fragments from parental TGF-beta proteins operably linked such that the resulting polypeptide is capable of modulating a pathway associated with a TGF-beta family member. In one embodiment, the pathway is a SMAD or DAXX pathway.Type: GrantFiled: May 31, 2017Date of Patent: November 29, 2022Assignees: MOGAM INSTITUTE FOR BIOMEDICAK RESEARCH, JOINT CENTER FOR BIOSCIENCESInventors: Sen Yon Choe, Chi Hoon Ahn, Ho Cheol Kim, Hyeon Jin Kim
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Publication number: 20220362355Abstract: Provided is a thrombolytic agent for ‘intravascular thrombus’, and more particularly, to a thrombolytic agent having a thrombo-recognition domain and a thrombolytic domain. It also relates to a polypeptide for thrombolysis of an intravascular thrombus, a gene for that polypeptide, and a pharmaceutical composition containing the same. The polypeptide that recognizes ‘intravascular thrombus’ and dissolves thrombus of the present invention is characterized in that it consists of a thrombolytic domain comprising the amino acid sequence set forth in SEQ ID NO: 1 or SEQ ID NO: 2 and a thrombo-recognition domain comprising the amino acid sequence set forth in SEQ ID NO: 3 or SEQ ID NO: 4. According to the present invention, the polypeptide for dissolving thrombus by recognizing ‘intravascular thrombus’ dissolves thrombus in the blood of a mammal without serious bleeding side effects has a preventive and therapeutic effect on thrombosis, thus preventing thrombosis and related diseases.Type: ApplicationFiled: October 19, 2020Publication date: November 17, 2022Inventors: Seong Tshool HONG, Hyeon Jin KIM, Mdmehedi HASSAN
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Publication number: 20220310332Abstract: Disclosed herein is an electrochemical device forming a chip-capacitor or a super-capacitor. The electrochemical device includes: a ceramic substrate having a nonconductive ceramic layer, a current collecting layer disposed on a nonconductive ceramic layer and made of ceramic or cermet, and a metal layer arranged on outer surfaces of the nonconductive ceramic layer and the current collecting layer; an electrode having a positive electrode and a negative electrode and formed on the current collecting layer; and a nonconductive ceramic packaging module located on the ceramic substrate to accommodate electrolyte therein, wherein the metal layer is exposed to the outside of the nonconductive ceramic packaging module.Type: ApplicationFiled: May 10, 2021Publication date: September 29, 2022Applicant: KOREA INSTITUTE OF ENERGY RESEARCHInventors: Jung Joon YOO, Ji Haeng YU, Kyong Sik YUN, Jeong Hun BAEK, Hyeon Jin KIM
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Patent number: 11364789Abstract: A hybrid powertrain may include a first shifting module including a motor input shaft having a motor directly connected to the motor shaft and provided to form two shifting stages having the largest gear ratios in sequence among a series of shifting stages; a second shifting module including an engine input shaft concentrically mounted with the motor input shaft and connected to an engine through a main clutch, and provided to form the remaining shifting stages of the series of shifting stages; a center synchro mounted to intermit the motor input shaft and the engine input shaft; and a continuous variable device provided to implement a state in which the first shifting module forms a gear ratio smaller than a shifting stage having a small gear ratio among the shifting stages of the first shifting module by a continuously controlled friction force.Type: GrantFiled: January 16, 2020Date of Patent: June 21, 2022Assignees: Hyundai Motor Company, Kia Motors CorporationInventors: Jong Yun Park, Dong Woo Gwak, Seong Eun Yun, Sung Wha Hong, Hyeon Jin Kim, Jin Seung Lim
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Publication number: 20220163513Abstract: The disclosure provides methods, systems and related software, for automated or semi-automated sorting and/or isolating cells with visually distinguishable phenotypes. In some embodiments, the methods comprise providing a plurality cells with a photo-activatable detectable marker in their respective nuclei. The plurality of cells are imaged and, based on the image, the status for one or more visually identifiable phenotypes are determined. Cells determined to have the desired phenotype status are specifically exposed to a light wavelength for a time sufficient to uniquely activate the photo-activatable detectable marker in the individual cells with the desired phenotype status. The cells are then sorted on the basis of the activated detectable marker. The disclosure also provides methods for preparation and isolation of nuclei from fixed, adherent cells for analysis.Type: ApplicationFiled: November 22, 2021Publication date: May 26, 2022Applicant: University of WashingtonInventors: Douglas Fowler, Nicholas Hasle, Sriram Pendyala, Hyeon-Jin Kim
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Patent number: 11273188Abstract: Provided are gut microbes or cultures having anti-obesity efficacy and a pharmaceutical composition containing them. The gut microbes or cultures have anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in a mammalian gastrointestinal tract for the prevention and treatment of obesity and obesity related diseases. This invention demonstrated that said gut microbes having anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in the gastrointestinal tract of mammals have the anti-obesity efficacy as much as that of the representative anti-obesity drug, orlistat, without any side effects in animal experiments and clinical trials. Therefore, the gut microbes h can be used to develop universal anti-obesity drugs for obese patients, contributing greatly to the health of mankind.Type: GrantFiled: November 8, 2016Date of Patent: March 15, 2022Assignee: MICROBIOTICA GMBHInventors: Hyeon Jin Kim, Seong Tshool Hong, Jae Gak Yu
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Patent number: 11247555Abstract: A power train for an electric vehicle may include an input shaft to which a motor is fixedly connected; a driving gear rotatably mounted on the input shaft; an output shaft disposed in parallel to the input shaft; a driven gear fixed to the output shaft and gear-engaged with the driving gear; a planetary gear set including first, second and third rotation elements wherein the first rotation element is fixedly connected to the input shaft and the second rotation element is fixedly connected to the driving gear, and the third rotation element is restrained from rotating; a friction clutch configured for selectively connecting the input shaft to the driving gear and configured for selectively connecting the input shaft to the driving gear; and a restraining device provided to the third rotation element to implement two states so that only one-way rotation of the third rotation element of the planetary gear set is restrained or two-way rotation thereof is restrained.Type: GrantFiled: September 4, 2020Date of Patent: February 15, 2022Assignees: Hyundai Motor Company, Kia Motors CorporationInventors: Jong Yun Park, Jin Seung Lim, Byung Dae Choi, Sung Wha Hong, Dong Woo Gwak, Hyeon Jin Kim, Seong Eun Yun
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Publication number: 20210370764Abstract: A power train for an electric vehicle may include an input shaft to which a motor is fixedly connected; a driving gear rotatably mounted on the input shaft; an output shaft disposed in parallel to the input shaft; a driven gear fixed to the output shaft and gear-engaged with the driving gear; a planetary gear set including first, second and third rotation elements wherein the first rotation element is fixedly connected to the input shaft and the second rotation element is fixedly connected to the driving gear, and the third rotation element is restrained from rotating; a friction clutch configured for selectively connecting the input shaft to the driving gear and configured for selectively connecting the input shaft to the driving gear; and a restraining device provided to the third rotation element to implement two states so that only one-way rotation of the third rotation element of the planetary gear set is restrained or two-way rotation thereof is restrained.Type: ApplicationFiled: September 4, 2020Publication date: December 2, 2021Applicants: Hyundai Motor Company, Kia Motors CorporationInventors: Jong Yun PARK, Jin Seung Lim, Byung Dae Choi, Sung Wha Hong, Dong Woo Gwak, Hyeon Jin Kim, Seong Eun Yun
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Patent number: 11181173Abstract: A powertrain for an electric vehicle, may include: an input shaft and an output shaft mounted in parallel to each other; first and second power transmission mechanisms provided to transmit power from the input shaft to the output shaft at two gear ratios different from each other; a one-way clutch included in the first power transmission mechanism; a friction clutch included in the second power transmission mechanism; and a bypass mechanism provided to form a power transmission path that bypasses the one-way clutch and a power transmission path that bypasses the friction clutch.Type: GrantFiled: September 30, 2020Date of Patent: November 23, 2021Assignees: Hyundai Motor Company, Kia Motors CorporationInventors: Jong Yun Park, Hang Chul Cho, Sang Bum Baek, Byung Dae Choi, Seong Eun Yun, Joon Lee, Sung Wha Hong, Hyeon Jin Kim
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Publication number: 20210236637Abstract: Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, “metal ion-noncovalently bound apotransferrin” (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer.Type: ApplicationFiled: March 31, 2021Publication date: August 5, 2021Applicant: JINIS CO., LTD.Inventors: Hyeon Jin KIM, Seong Tshool Hong, Hea Jong Chung, Heui Kwan Lee, Hea Guk Cho, Jae Gak Yu
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Patent number: 10991103Abstract: A method for extracting a person region includes detecting a face from a raw image input in real time; configuring a search range based on the detected face; extracting an outline of a person region by performing preprocessing on an image within the search range; configuring watershed markers on a background and a foreground of the image within the search range based on the extracted outline; performing a watershed transform based on the configured watershed markers; and separating the person region from the raw image using a result of the watershed transform.Type: GrantFiled: October 18, 2019Date of Patent: April 27, 2021Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Won Seok Chae, Hyeon Jin Kim, Soo Myung Park, Ah Reum Oh, Ha Lim Choi
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Publication number: 20210081768Abstract: A clustering method includes configuring a network with clustering target objects; collecting significance of the clustering target objects; performing network embedding for outputting a set of vectors representing neighboring objects of the clustering target objects constituting the network using a neural network; and performing clustering on the clustering target objects using the set of vectors and information on each of the clustering target objects, wherein the neural network is trained so that neighboring objects having high significance are output with higher probability.Type: ApplicationFiled: October 22, 2019Publication date: March 18, 2021Inventors: Yeo Chan YOON, Hyeon Jin KIM, Soo Myung PARK, Hyung Keun JEE
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Publication number: 20210070162Abstract: A hybrid powertrain may include a first shifting module including a motor input shaft having a motor directly connected to the motor shaft and provided to form two shifting stages having the largest gear ratios in sequence among a series of shifting stages; a second shifting module including an engine input shaft concentrically mounted with the motor input shaft and connected to an engine through a main clutch, and provided to form the remaining shifting stages of the series of shifting stages; a center synchro mounted to intermit the motor input shaft and the engine input shaft; and a continuous variable device provided to implement a state in which the first shifting module forms a gear ratio smaller than a shifting stage having a small gear ratio among the shifting stages of the first shifting module by a continuously controlled friction force.Type: ApplicationFiled: January 16, 2020Publication date: March 11, 2021Applicants: Hyundai Motor Company, Kia Motors CorporationInventors: Jong Yun PARK, Dong Woo Gwak, Seong Eun Yun, Sung Wha Hong, Hyeon Jin Kim, Jin Seung Lim
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Patent number: 10858006Abstract: A backward driving control method for a hybrid vehicle may include a condition determination operation of, when the driver performs a shifting to a reverse gear stage, determining whether the rotation speed of a motor in the forward direction exceeds a reference speed and whether the torque of the motor exceeds a reference torque, a first backward driving operation of, when the rotation speed of the motor exceeds the predetermined reference speed and when the torque of the motor exceeds the predetermined reference torque, implementing the reverse gear stage using a backward driving implementation device of the transmission, a zero-torque control operation of decreasing the torque of the motor to zero, a forward driving conversion operation of shifting the transmission to a forward gear stage, and a second backward driving operation of driving the motor in the reverse direction to implement the reverse gear stage.Type: GrantFiled: August 13, 2019Date of Patent: December 8, 2020Assignees: Hyundai Motor Company, Kia Motors CorporationInventors: June Ho Lee, Hyeon Jin Kim
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Publication number: 20200325216Abstract: A non-naturally occurring chimeric polypeptide having an activity provided by a TGF-beta family member is disclosed. The chimeric polypeptide of an embodiment comprises two or more domains or fragments from parental TGF-beta proteins operably linked such that the resulting polypeptide is capable of modulating a pathway associated with a TGF-beta family member. In one embodiment, the pathway is a SMAD or DAXX pathway.Type: ApplicationFiled: May 31, 2017Publication date: October 15, 2020Applicants: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, JOINT CENTER FOR BIOSCIENCEInventors: Sen Yon CHOE, Chi Hoon AHN, Ho Cheoi KIM, Hyeon Jin KIM
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Publication number: 20200307587Abstract: A backward driving control method for a hybrid vehicle may include a condition determination operation of, when the driver performs a shifting to a reverse gear stage, determining whether the rotation speed of a motor in the forward direction exceeds a reference speed and whether the torque of the motor exceeds a reference torque, a first backward driving operation of, when the rotation speed of the motor exceeds the predetermined reference speed and when the torque of the motor exceeds the predetermined reference torque, implementing the reverse gear stage using a backward driving implementation device of the transmission, a zero-torque control operation of decreasing the torque of the motor to zero, a forward driving conversion operation of shifting the transmission to a forward gear stage, and a second backward driving operation of driving the motor in the reverse direction to implement the reverse gear stage.Type: ApplicationFiled: August 13, 2019Publication date: October 1, 2020Applicants: Hyundai Motor Company, Kia Motors CorporationInventors: June Ho LEE, Hyeon Jin KIM
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Publication number: 20200250830Abstract: A method for extracting a person region includes detecting a face from a raw image input in real time; configuring a search range based on the detected face; extracting an outline of a person region by performing preprocessing on an image within the search range; configuring watershed markers on a background and a foreground of the image within the search range based on the extracted outline; performing a watershed transform based on the configured watershed markers; and separating the person region from the raw image using a result of the watershed transform.Type: ApplicationFiled: October 18, 2019Publication date: August 6, 2020Inventors: Won Seok CHAE, Hyeon Jin KIM, Soo Myung PARK, Ah Reum OH, Ha Lim CHOI
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Publication number: 20200061132Abstract: Provided are gut microbes or cultures having anti-obesity efficacy and a pharmaceutical composition containing them. The gut microbes or cultures have anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in a mammalian gastrointestinal tract for the prevention and treatment of obesity and obesity related diseases. This invention demonstrated that said gut microbes having anti-obesity efficacy by lowering fatty acid concentration of the gut fluid contents in the gastrointestinal tract of mammals have the anti-obesity efficacy as much as that of the representative anti-obesity drug, orlistat, without any side effects in animal experiments and clinical trials. Therefore, the gut microbes h can be used to develop universal anti-obesity drugs for obese patients, contributing greatly to the health of mankind.Type: ApplicationFiled: November 8, 2016Publication date: February 27, 2020Applicant: JINIS CO., LTD.Inventors: Hyeon Jin KIM, Seong Tshool HONG, Jae Gak YU